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Hotspots and trends of risk factors in gastric cancer: A visualization and bibliometric analysis

World Journal of Gastrointestinal Oncology 2024年第5期16卷 2200-2218页

作者： Meng Li Ning Gao Shao-Li Wang Yu-Feng Guo Zhen Liu department of Gastroenterology Guang'anmen HospitalChina Academy of Chinese Medical SciencesBeijing 100053China department of Acupuncture and Moxibustion Guang'anmen HospitalChina Academy of Chinese Medical SciencesBeijing 100053China

BACKGROUND The lack of specific symptoms of gastric cancer(GC)causes great challenges in its early *** it is essential to identify the risk factors for early diagnosis and treatment of GC and to improve the survival *** To assist physicians in identifying changes in the output of publications and research hotspots related to risk factors for GC,constructing a list of key risk factors,and providing a reference for early identification of patients at high risk for *** Research articles on risk factors for GC were searched in the Web of Science core collection,and relevant information was extracted after *** literature was analyzed using Microsoft Excel 2019,CiteSpace V,and VOSviewer *** A total of 2514 papers from 72 countries and 2507 research institutions were ***(n=1061),National Cancer Center(n=138),and Shoichiro Tsugane(n=36)were the most productive country,institution,or author,*** research hotspots in the study of risk factors for GC are summarized in four areas,namely:Helicobacter pylori(***)infection,single nucleotide polymorphism,bio-diagnostic markers,and GC risk prediction *** In this study,we found that *** infection is the most significant risk factor for GC;single-nucleotide polymorphism(SNP)is the most dominant genetic factor for GC;bio-diagnostic markers are the most promising diagnostic modality for *** risk prediction models are the latest current research *** conclude that the most important risk factors for the development of GC are *** infection,SNP,smoking,diet,and alcohol.

关键词： Gastric cancer Risk factor Bibliometric Research hotspots VOSviewer

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Structural engineering of BaWO_(4)/CsPbX_(3)/CsPb_(2)X_(5)(X=Cl,Br,I)heterostructures towards ultrastable and tunable photoluminescence

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Nano Research 2024年第3期17卷 1636-1645页

作者： Peng Liu Yan Xu Bohan Li Yuchi Zhang Hongzhou Lian Jun Lin department of Chemistry College of SciencesNortheastern UniversityShenyang 110819China State Key Laboratory of Rare Earth Resource Utilization Chang Chun Institute of Applied ChemistryChinese Academy of SciencesChangchun 130022China

Construction of lead halide perovskite nanocrystals(LHP NCs)heterostructures is essential to obtain highly stable photoluminescence and expand their ***,a novel self-assembly strategy combining with a solvent-free thermal-assisted synthesis and a water-triggered reaction is developed to subsequently grow BaWO_(4)/CsPbX_(3)/CsPb_(2)X_(5)(X=Cl,Br,I)heterostructures at low nucleation temperature with high *** as-obtained ternary BaWO_(4)/CsPbX_(3)/CsPb_(2)X_(5)(X=Cl,Br,I)heterostructures exhibit remarkably enhanced panchromatic emission and ultrastable luminescence ascribing to the low-defect growth based on lattice *** white light-emitting diodes(WLEDs)have been constructed with a high correlated color temperature(CCT)of 7225 K and luminous efficiency of 74.4 lm·***^(3+)-doped BaWO_(4)/CsPbX_(3)/CsPb_(2)X_(5)(Ln^(3+)=Eu^(3+),Tb^(3+),Dy^(3+),Sm^(3+),Yb^(3+)/Er^(3+))nanocomposites are further designed with excitation-dependent photoluminescence and thermochromic properties,making them excellent candidates for high-level anti-counterfeiting and *** work offers a green and universal approach in assembling CsPbX_(3)(X=Cl,Br,I)on lattice-matched tungstate with adjustable panchromatic emission for versatile optical applications.

关键词： inorganic lead halide perovskites solvent-free synthesis panchromatic emission anti-counterfeiting and encryption application

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Sulfation of chondroitin and bile acids converges to antagonize Wnt/β-catenin signaling and inhibit APC deficiency-induced gut tumorigenesis

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Acta Pharmaceutica Sinica B 2024年第3期14卷 1241-1256页

作者： Pengfei Xu Yue Xi Jong-Won Kim Junjie Zhu Min Zhang Meishu Xu Songrong Ren Da Yang Xiaochao Ma Wen Xie Center for Pharmacogenetics and department of Pharmaceutical sciences University of PittsburghPittsburghPA 15261USA department of Hepatobiliary and Pancreatic Surgery Zhongnan Hospital of Wuhan UniversitySchool of Pharmaceutical SciencesWuhan UniversityWuhan 430071China department of Pharmacology&Chemical Biology University of PittsburghPittsburghPA 15261USA

Sulfation is a crucial and prevalent conjugation reaction involved in cellular processes and mammalian physiology.3’-Phosphoadenosine 5’-phosphosulfate(PAPS)synthase 2(PAPSS2)is the primary enzyme to generate the universal sulfonate donor *** involvement of PAPSS2-mediated sulfation in adenomatous polyposis coli(APC)mutation-promoted colonic carcinogenesis has not been ***,we showed that the expression of PAPSS2 was decreased in human colon tumors along with cancer stages,and the lower expression of PAPSS2 was correlated with poor prognosis in advanced colon *** epithelial-specific heterozygous Apc deficient and Papss2-knockout(Apc^(Δgut-Het)Papss2^(Δgut))mice were created,and the phenotypes were compared to the spontaneous intestinal tumorigenesis of Apc^(Δgut-Het)***^(Δgut-Het)Papss2^(Δgutmice) were more sensitive to gut tumorigenesis,which was mechanistically accounted for by the activation of Wnt/β-catenin signaling pathway due to the suppression of chondroitin sulfation and inhibition of the farnesoid X receptor(FXR)-transducin-like enhancer of split 3(TLE3)gene regulatory *** sulfate supplementation in Apc^(Δgut-Het)Papss2^(Δgutmice) alleviated intestinal *** summary,we have uncovered the protective role of PAPSS2-mediated chondroitin sulfation and bile acids-FXR-TLE3 activation in the prevention of gut carcinogenesis via the antagonization of Wnt/β-catenin *** sulfate may be explored as a therapeutic agent for Papss2 deficiency-associated colonic carcinogenesis.

关键词： Colon cancer APC Wnt/b-catenin PAPSS2 Chondroitin sulfate Sulfation Bile acids FXR

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Dilation,discrimination and Uhlmann's theorem of link products of quantum channels

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Chinese Physics B 2024年第3期33卷 201-206页

作者：雷强操刘桁 Asutosh Kumar 武俊德 School of Mathematical sciences Harbin Institute of TechnologyHarbin 150001China department of Physics Gaya CollegeMagadh UniversityRampurGaya 823001India School of Mathematical sciences Zhejiang UniversityHangzhou 310027China

We establish the Stinespring dilation theorem of the link product of quantum channels in two different ways,discuss the discrimination of quantum channels,and show that the distinguishability can be improved by self-linking each quantum channel n times as n *** also find that the maximum value of Uhlmann's theorem can be achieved for diagonal channels.

关键词： quantum channels link products Stinespring dilation theorem Uhlmann's theorem

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Mutations in wheat TaAPA2 gene result in pleiotropic effects on plant architecture

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Science China(Life sciences) 2024年第9期67卷 2039-2042页

作者： Shengsheng Bai Guiping Wang Rui Song Yanna Liu Lei Hua Jinwei Yang Lijun Zhang Shams ur Rehman Xiaohua Hao Lifeng Hou Chaozhong Zhang Hongna Li Yanyan Liang Lihua Zhao Yan Xue Zheng Wang Shisheng Chen National Key Laboratory of Wheat Improvement Peking University Institute of Advanced Agricultural SciencesShandong Laboratory of Advanced Agriculture Sciences in WeifangWeifang 261325China department of Plant sciences University of CaliforniaDavisCA 95616USA

Dear Editor,Bread wheat(Triticum aestivum L.)is a globally important cereal providing~20% of the calories and proteins for>4.5billion *** architecture,including morphologies of leaves,spikes,stems,and roots,has great impact on plant development and productivity,and thus has been extensively investigated in various plant species(Jiang et al.,2023;Zhang et al.,2017).

关键词： cereal globally roots

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Decoupling of temporal/spatial broadening effects in Doppler wind LiDAR by 2D spectral analysis

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Chinese Physics B 2024年第3期33卷 447-452页

作者：刘珍张云鹏竹孝鹏刘继桥毕德仓陈卫标 Space Laser Engineering department Shanghai Institute of Optics and Fine MechanicsChinese Academy of SciencesShanghai 201800China Center of Materials Science and Optoelectronics Engineering University of Chinese Academy of SciencesBeijing 100049China

Pulse echo accumulation is commonly employed in coherent Doppler wind LiDAR(light detection and ranging)under the assumption of steady ***,the measured spectral data are analyzed in the time dimension and frequency dimension to cope with the temporal wind shear and achieve the optimal accumulation time.A hardware-efficient algorithm combining the interpolation and cross-correlation is used to enhance the wind retrieval accuracy by reducing the frequency sampling interval and then reduce the spectral width calculation ***,the temporal broadening effect and spatial broadening effect are decoupled according to the strategy we developed.

关键词： Doppler wind LiDAR spectral analysis hardware efficiency spectrum broadening effects

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The TaGW2‐TaSPL14 module regulates the trade‐off between tiller number and grain weight in wheat

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Journal of Integrative Plant Biology 2024年第9期66卷 1953-1965页

作者： Chao Jian Yuxue Pan Shujuan Liu Mengjiao Guo Yilin Huang Lina Cao Weijun Zhang Liuling Yan Xueyong Zhang Jian Hou Chenyang Hao Tian Li State Key Laboratory of Crop Gene Resources and Breeding Institute of Crop SciencesChinese Academy of Agricultural SciencesBeijing 100081China Crop Research Institute Ningxia Academy of Agriculture and Forestry SciencesYinchuan 750002China department of Plant and Soil sciences Oklahoma State UniversityStillwaterOklahoma 74078USA

IDEAL PLANT ARCHITECTURE1(IPA1)is a pivotal gene controlling plant architecture and grain ***,little is known about the effects of Triticum aestivum SQUAMOSA PROMOTER‐BINDING‐LIKE 14(TaSPL14),an IPA1 ortholog in wheat,on balancing yield traits and its regulatory mechanism in wheat(*** L.).Here,we determined that the *** GRAIN WIDTH2(TaGW2)‐TaSPL14 module influences the balance between tiller number and grain weight in *** of TaSPL14 resulted in a reduced tiller number and increased grain weight,whereas its knockout had the opposite effect,indicating that TaSPL14 negatively regulates tillering while positively regulating grain *** further identified TaGW2 as a novel interacting protein of TaSPL14 and confirmed its ability to mediate the ubiquitination and degradation of *** on our genetic evidence,TaGW2 acts as a positive regulator of tiller number,in addition to its known role as a negative regulator of grain weight,which is opposite to ***,combinations of TaSPL14‐7A and TaGW2‐6A haplotypes exhibit significantly additive effects on tiller number and grain weight in wheat *** findings provide insight into how the TaGW2‐TaSPL14 module regulates the trade‐off between tiller number and grain weight and its potential application in improving wheat yield.

关键词： grain weight TaGW2 TaSPL14 tiller number wheat

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Novel Framework for an Intrusion Detection System Using Multiple Feature Selection Methods Based on Deep Learning

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Tsinghua Science and Technology 2024年第4期29卷 948-958页

作者： A.E.M.Eljialy Mohammed Yousuf Uddin Sultan Ahmad department of Information Systems College of Computer Engineering and SciencesPrince Sattam Bin Abdulaziz UniversityAlkharjSaudi Arabia department of Computer Science College of Computer Engineering and SciencesPrince Sattam Bin Abdulaziz UniversityAlkharjSaudi Arabiaand also with University Center for Research and Development(UCRD)Department of Computer Science and EngineeringChandigarh UniversityPunjabIndia

Intrusion detection systems (IDSs) are deployed to detect anomalies in real time. They classify a network’s incoming traffic as benign or anomalous (attack). An efficient and robust IDS in software-defined networks is an inevitable component of network security. The main challenges of such an IDS are achieving zero or extremely low false positive rates and high detection rates. Internet of Things (IoT) networks run by using devices with minimal resources. This situation makes deploying traditional IDSs in IoT networks unfeasible. Machine learning (ML) techniques are extensively applied to build robust IDSs. Many researchers have utilized different ML methods and techniques to address the above challenges. The development of an efficient IDS starts with a good feature selection process to avoid overfitting the ML model. This work proposes a multiple feature selection process followed by classification. In this study, the Software-defined networking (SDN) dataset is used to train and test the proposed model. This model applies multiple feature selection techniques to select high-scoring features from a set of features. Highly relevant features for anomaly detection are selected on the basis of their scores to generate the candidate dataset. Multiple classification algorithms are applied to the candidate dataset to build models. The proposed model exhibits considerable improvement in the detection of attacks with high accuracy and low false positive rates, even with a few features selected.

关键词： random forest feature selection decision tree software-defined network logistic regression intrusion detection system XGB classifier AdaBoost

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Synthesis of hierarchically porous carbon materials by zinc salts-assisted carbonization of biomass and organic solid wastes

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Particuology 2024年第1期84卷 45-52页

作者： Le-Le Zhang Lei Tong Yanwei Ding Wanqun Zhang Hai-Wei Liang Hefei National Research Center for Physical sciences at the Microscale Department of ChemistryUniversity of Science and Technology of ChinaHefei230026China

Hierarchically porous carbons(HPCs)with multimodal pores have attracted considerable attention due to their unique physical and chemical properties and various application potentials in heterogeneous catalysis,environmental treatment,and energy storage and ***,we report a general and simple zinc salts-assisted method for the synthesis of HPCs with varied porosity and chemical func-tionalities by the direct carbonization of diverse biomass and *** the carbonization,zinc salts are thermally decomposed into nanoparticles that serve as in-situ templates to introduce nanopores in *** prepared HPCs exhibit high specific surface areas(up to 2432 m2 g-1),large pore volumes(up to 4.30 cm^(3)g^(-1)),and broad pore size ***,the zinc salts can be recovered and recycled,supporting the sustainable production of HPCs on large *** prepared HPCs-supported catalysts with atomically dispersed metal sites exhibit promising electrocatalytic performance for the oxygen reduction reaction.

关键词： Hierarchical porous carbon Zinc salts Biomass Wastes Electrocatalysis

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High-Temperature Superconductivity in La_(3)Ni_(2)O_(7)

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Chinese Physics Letters 2024年第1期41卷 85-91页

作者：蒋坤汪自强张富春 Beijing National Laboratory for Condensed Matter Physics and Institute of PhysicsChinese Academy of SciencesBeijing 100190China School of Physical sciences University of Chinese Academy of SciencesBeijing 100190China department of Physics Boston CollegeChestnut HillMA 02467USA Kavli Institute of Theoretical sciences University of Chinese Academy of SciencesBeijing 100190China Collaborative Innovation Center of Advanced Microstructures Nanjing UniversityNanjing 210093China

Motivated by the recent discovery of high-temperature superconductivity in bilayer La_(3)Ni_(2)O_(7) under pressure,we study its electronic properties and superconductivity due to strong electron *** the inversion symmetry,we decouple the low-energy electronic structure into block-diagonal symmetric and antisymmetric *** is found that the antisymmetric sector can be reduced to a one-band system near half filling,while the symmetric bands occupied by about two electrons are heavily overdoped *** the strong coupling mean field theory,we obtain strong superconducting pairing with B_(1g)symmetry in the antisymmetric *** propose that due to the spin-orbital exchange coupling between the two sectors,B_(1g)pairing is induced in the symmetric bands,which in turn boosts the pairing gap in the antisymmetric band and enhances the high-temperature superconductivity with a congruent d-wave symmetry in pressurized La_(3)Ni_(2)O_(7).

关键词： symmetry superconductivity symmetric

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