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Awareness, Knowledge, Perception and Attitude towards Prescription medicines Abuse among medicines Prescribers and Dispensers in Nnewi Nigeria

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Pharmacology & Pharmacy 2015年第5期6卷 254-266页

作者： Prosper Obunikem Uchechukwu Adogu Ifeoma A. Njelita Nonye Bibiana Egenti Chika Florence Ubajaka Ifeoma A. Modebe consultant Public Health physician (MBBS FWACP FMCPH) Department of Community Medicine NAU/NAUTH Nnewi Nigeria consultant Public Health physician (MBBS MPH FWACP) Department of Community Medicine NAUTH Nnewi Nigeria consultant Public Health physician (MBBS MPH FMCPH) Department of Community Medicine University of Abuja Abuja Nigeria consultant Public Health physician (MBBS FMCPH) Department of Community Medicine NAU/NAUTH Nnewi Nigeria consultant Public Health physician (MBBS FWACP) Department of Community Medicine NAU/NAUTH Nnewi Nigeria

Background: Abuse of medicines is becoming a serious problem in many parts of the world, with negative consequences ranging from addiction, psychosis, cardiovascular complications, and premature deaths from unintentional overdose. Objectives: The objective of this study is to assess awareness, knowledge, perception and attitudes toward the abuse of prescription medicines (PM) among medicines prescribers and dispensers in Nigeria. Design and Participants: A descriptive cross-sectional study was carried out among pharmacists, other pharmacy staff in retail pharmacies, licensed patent medicines vendors (chemical sellers), and medical doctors in Nnewi, Nigeria. Data were collected through self-completed questionnaire supervised by trained research assistants, between December 2013 and April 2014. Three hundred and seventy-five participants were recruited for this study. Data Analysis: The Statistical Package for the Social Sciences (SPSS) version 17 for windows was used for data analysis. Bivariate and multivariate analyses were carried out to evaluate differences and associations based on selected variables. Results: The perception was high 294 (78.4%) among respondents that PM abuse was a problem in the community. Knowledge of health problems associated with PM abuse was also high at 226 (60.3%). However the attitude of the respondents towards early detection of PM abuse among their patients/clients was discouraging. Education, educational status, work status and gender significantly predict good knowledge and positive attitude about PM abuse. Conclusion: Findings from this study will assist health authorities to formulate appropriate health promotion interventions to control and prevent abuse of prescription medicines. Actions directed at early intervention, capacity building, education, public health initiatives and law enforcements will hopefully curb the menace of PM abuse in Nnewi, Nigeria.

关键词： Prescription medicine Abuse Knowledge Attitude Nnewi Nigeria

Secondary damage in trauma and limited access dressing: a review

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Plastic and Aesthetic Research 2020年第6期7卷 1-11页

作者： Pramod Kumar Akriti Gupta Apoorva Gupta consultant Plastic Surgeon King Fahd Central HospitalJazan 82666Saudi Arabia Resident physician(Pathology) University of VirginiaCharlottesvilleVA 22903USA physician(Internal medicine) Asante Rogue Regional Medical CenterMedfordOR 97504USA

Secondary damage in trauma may increase morbidity,mortality and the cost of treatment *** article reviews the literature of 46 relevant articles on this *** hope to provide a better understanding of the various mechanisms that can lead to secondary damage following major trauma and aim to improve the management of such in trauma *** also explore the utility of limited access dressing and its ability to minimize and treat secondary musculoskeletal *** interdependent cellular mechanisms have been described that contribute and perpetuate secondary tissue damage-lysosomal,protein/enzyme denaturation,membrane permeability and *** changes are mainly due to systemic hypoxia and the systemic inflammatory response *** access dressing appears to be an efficient and cost-effective method for the management of secondary damage,as evidenced by the reduced number of debridements,shorter wound coverage time,and reduction in total length of hospital stay while lowering treatment costs and improving quality of care.

关键词： Trauma secondary damage limited access dressing

Detection of alcoholic liver disease

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World Journal of Gastroenterology 2001年第3期7卷 297-302页

作者： Harriet Gordon consultant physician and Gastroenterologist The Royal Hampshire County HospitalWinchesterHampshireUK

INTRODUCTIONAlcohol has been used in society over centuries and all over the world for its mood-lifting properties and taste. It is probably ,however ,the commonest drug of abuse world-wide and unfortunately causes considerable morbidity, mortality and social disruption .In 1990 the cost tl the USA was more than $ 100 billion and 100 000 lives.The relationship between alcohol and mankind is well documented from the earliest tines .

关键词： Biological Markers Humans Liver Diseases, Alcoholic

Esophageal ulceration complicating doxycycline therapy

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World Journal of Gastroenterology 2003年第3期9卷 609-611页

作者： Mohammad A.Al-Mofarreh Ibrahim A.Al Mofleh consultant physician & Gastroenterologist Poly ClinicCollege of MedicineKing Saud UniversityRiyadhSaudi Arabia Professor of medicine College of MedicineKing Saud UniversityRiyadh

AIM;TO report present state of iatrogenic drug-induced esophageal injury(DIEI)induced by medications in a private clinic. METHODS:Iatrogenic drug-induced esophageal injury (DIEI)induced by medications has been more frequently *** a private clinic we encountered 36 cases of esophageal ulcerations complicating doxycycline therapy in a mainly younger Saudi population(median age 29 years). RESULTS:The most frequent presenting symptoms were odynophagia,retrosternal burning pain and dysphagia(94 %, 75 % and 56 %,respectively).The diagnosis was according to medical history and confirmed by endoscopy in all patients. Beside withdrawal of doxycycline,when feasible,all patients were treated with a proton-pump inhibitor(PPI)and a *** patients who reported to the clinic after treatment were improved within 1-7(median 1.7)days. CONCLUSION:Esophageal ulceration has to be suspected in younger patients with odynophagia,retrosternal burning pain and/or dysphagia during the treatment with doxycycline.

关键词： Adolescent Adult Aged Child Doxycycline Esophageal Diseases Female Humans Iatrogenic Disease Male Middle Aged Retrospective Studies Ulcer

Atrial fibrillation in older patients reducing stroke risk is not only about anticoagulation

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Journal of Geriatric Cardiology 2016年第10期13卷 880-882页

作者： Nay Thu Win Shyh Poh Teo Medical Officer Department of Internal Medicine RIPAS Hospital Brunei Darussalam consultant Geriatrician and physician Department of Internal Medicine RIPAS Hospital Brunei Darussalam

Atrial fibrillation （AF） is associated with a five-fold increased risk of ischaemic stroke, stroke recurrence and mortality. Anticoagulant therapy may reduce the risk of recurrent stroke by approximately 60% and is ... 详细信息

关键词： Atrial fibrillation Bleeding Hypertension Stroke Warfarin

Defining an evidence base for treatment and treatment modalities in patients with Acromegaly

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Defining an evidence base for treatment and treatment modali...

Electrodiagnosis in Radiculopathy

2008内分泌代谢性疾病系列研讨会暨中青年英文论坛

作者： Paul M Stewart University of Birmingham and consultant physician Queen Elizabeth HospitalBirminghamUK MD FRCP FMedSci Professor of Medicine

Acromegaly is invariably caused by a GH secreting pituitary tumour and results in significant patient morbidity and premature cardiovascular *** options first and foremost should reverse the disabling symptoms(headache,sweating,tiredness,paraesthesia,arthralgia, snoring)and address the pituitary tumour itself,ideally with total excision and prevention of *** last 10 years has also seen an evidence base for the biochemical follow-up and"cure"of patients with Acromegaly,with a series of retrospective follow-up studies showing normalization of mortality rates if GH can be reduced to<5 mU/L(2.5 ?g/L).

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Electrodiagnosis in Radiculopathy

Acute ascites as a clinical manifestation of dengue: A case report

中国康复医学会电诊断专业委员会换届暨学术研讨会

作者：李常威 consultant physician in Rehabilitation medicine Tung Wah Hospital ＆ Hon.Clinical Associate Professor Department of MedicineThe University of Hong Kong

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Journal of Acute Disease 2020年第6期9卷 270-271页

作者： Beuy Joob Viroj Wiwanitkit Private Academic consultant Bangkok Thailand honorary professor dr DY Patil UniversityPuneIndia

Rationale:Dengue is an important tropical disease that can cause acute hemorrhagic *** atypical clinical presentations of dengue also can occur,and acute ascites is one of ***'concern:A 47-year-old male patient was referred to the physician with acute abdominal extension for 2 *** revealed a history of fatigue and right upper abdominal pain in the past 4 ***:Dengue-induced acute ***:Standard fluid replacement ***:The clinical finding of the patient returned to normal within 5 ***:Since dengue has been expanding its endemic area at present,an atypical clinical presentation is possible and should not be ignored in the process of *** addition,the clinical presentation of acute distention of abdomen with abnormal petechiae is a good diagnostic implication for dengue-induced ascites.

关键词： Dengue Ascites Acute Manifestation

Fertility and pregnancy in inflammatory bowel disease

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World Journal of Gastroenterology 2001年第4期7卷 455-459页

作者： Elspeth Alstead Senior Lecturer and consultant physician Department of Adult and Paediatric GastroenterologySt.Bartholomew's and the Royal London School of Medicine and DentistryTurner StreetLondon El 2ADUK.

INTRODUCTIONInflammatory bowel disease(IBD)is a chronic disorder affecting young adults in the reproductive *** is comon for both female and male patients with IBD to ask questions about IBD's effect on their relationships,sexual and reproductive function,in particular fertility,the outcome of pregnancy and its possible effets on the *** open discussion of the social situation and education targeted at these issues therefore forms an essential part of the management of any young person with *** questions that are most commonly asked are summarised in Table *** order to answer these questions we need *** are few large prospective case controlled studies to provide the information which is required but the available data,some of it from small observational studies,will be summarised in this chapter.

关键词： Fertility Female Humans Immunosuppressive Agents Inflammatory Bowel Diseases Pregnancy Pregnancy Complications Pregnancy Outcome