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Research Progress on Individualized Treatment of Splenic Aneurysm

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Expert Review of Chinese Medical

Expert Review of Chinese Medical 2024年第2期2卷 12-17页

作者： Shaodan Chen Jiayuan Chen Medical department of Qingdao University Wenzhou Medical college

Splenic artery aneurysm has a hidden onset and atypical *** are various diagnostic methods for splenic aneurysms,among which ultrasound is the first choice for aneurysm *** diagnostic rate of CTA and DSA reaches 100%.In clinical practice,it is necessary to integrate medical history,symptoms and signs,and multiple imaging results to improve the diagnostic *** terms of treatment plans,both intervention and surgical procedures have their strengths,and the application of intervention will be more *** need to adhere to the principle of individualization and choose a reasonable treatment plan for *** present,there are many reports on pregnant women with large splenic aneurysms both domestically and *** scholars believe that large splenic aneurysms may be related to hormonal imbalances during pregnancy,and the specific pathogenic mechanism will become a hot topic in future research.

关键词： splenic aneurysm diagnosis surgery interventional therapy individualized treatment plan

Accelerating snail vector genomics

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Infectious Diseases of Poverty 2024年第3期13卷 6-10页

作者： Tom Pennance David Rollinson college of Osteopathic Medicine of the Pacific-Northwest Western University of Health SciencesLebanonORUSA Global Schistosomiasis Alliance Ealing Cross85 Uxbridge RoadEalingLondon W55BWUK Science department Natural History MuseumCromwell RoadLondon SW75BDUK

The three most important genera of snails for the transmission of schistosomes are Bulinus,Biomphalaria and *** of these genera,found in two distantly related families,includes species that act as the intermediate host for one of the three most widespread schistosome species infecting humans,Schistosoma haematobium,*** and ***,*** important step in the fight against schistosomiasis in Asia has been taken with the publication of the article"Chromosome-level genome assembly of Oncomelania hupensis:the intermediate snail host of Schistosoma japonicum",which means that genomes for all three major genera,including species across three continents,are now available in the public *** includes the first genomes of African snail vectors,namely Biomphalaria sudanica,*** and Bulinus truncatus,as well as high-quality chromosome level assemblies for South American *** importantly,the wealth of new genomic and transcriptomic data is helping to establish the specific molecular mechanisms that underly compatibility between snails and their schistosomes,which although diverse and complex,may help to identify potential targets dictating host parasite interactions that can be utilised in future transmission control *** new work on Oncomelania hupensis and indeed studies on other snail vectors,which provide deep insights into the genome,will stimulate research that may well lead to new and much needed control interventions.

关键词： Snail vectors Genomics

A therapeutic potentiality and toxicity concern of nutrient plant Annona squamosa Linn.

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Traditional Medicine Research 2024年第3期9卷 52-65页

作者： Manisha Chandrakar Khomendra Kumar Sarwa Vijendra Kumar Suryawanshi Kumari Pramila University college of Pharmacy Raipur Chhattisgarh Swami Vivekanand Technical University BhilaiChhattisgarh 492001India department of Pharmacy Government Girls PolytechnicRaipurChhattisgarh 492001India Bharti college of Pharmacy Bharti UniversityDurgChhattisgarh 491001India Faculty of Pharmacy M J College BhilaiDurgChhattisgarh 490023India

Annona squamosa *** is famous for its nutritional value with a long history of medicinal benefits due to the presence of many phytochemicals,including alkaloids,diterpenes,essential oil,phytopeptides,*** studies envisaged that Annona squamosa possesses cytotoxic,diuretic,antiurolithiatic,antitumor,anti-psoriatic,antioxidant,and hepatoprotective *** plant is traditionally used for the treatment of wound infection,dysentery,seizure,tumors,fever,vomiting,parasitic infections,hypertension,thyroid,toothache,acne,heart disease,inflammation,diabetes,hair loss,dandruff,hemorrhage,maggot-infected sores,abortifacient,and ***,some chemical constituents isolated from the plant have shown specific toxic effects in human and animal models,such as acute oral toxic effects,genotoxic,neurotoxic,and ocular *** plant has diverse pharmacological actions,the seeds of this plant possess a genotoxic effect but on the contrary,the bark of the plant shows genoprotective activity.A large number of ethnobotanical studies reported the seed of this plant is used to induce abortion in humans,but a scientific study carried out in pregnant rats reported aqueous seed extract of the plant did not interfere with reproductive *** presented review summarized the traditional uses,pharmacological,and toxicological activities of the isolated compounds from this ***,some patents and commercial products related to Annona squamosa are also brought up in this article to explore its application which would attract the scientific community to search out its hidden side.

关键词： Annona squamosa cytotoxicity cancer abortifacient genotoxicity isosquamocin annonacin neurotoxicity ocular toxicity

Haplotype-resolved and chromosome-scale genomes provide insights into co-adaptation between the Amur tiger and Amur leopard

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Zoological Research 2024年第3期45卷 464-467页

作者： Hai-Meng Li Bo-Yang Liu Min-Hui Shi Le Zhang Shang-Chen Yang Sunil Kumar Sahu Liang-Yu Cui Shan-Lin Liu Nicolas Dussex Yue Ma Dan Liu Wei-Yao Kong Hao-Rong Lu Yue Zhao Love Dalén Huan Liu Tian-Ming Lan Guang-Shun Jiang Yan-Chun Xu college of Wildlife and Protected Area Northeast Forestry UniversityHarbinHeilongjiang 150040China State Key Laboratory of Agricultural Genomics BGI ResearchShenzhenGuangdong 518083China college of Life Sciences University of Chinese Academy of SciencesBeijing 100049China college of Life Sciences Zhejiang UniversityHangzhouZhejiang 310058China BGI Research WuhanHubei 430074China department of Entomology College of Plant ProtectionChina Agricultural UniversityBeijing 100193China Centre for Palaeogenetics Svante Arrhenius väg 20CStockholm 10691Sweden department of Zoology Stockholm UniversityStockholm 10691Sweden department of Bioinformatics and Genetics Swedish Museum of Natural HistoryStockholm 10691Sweden Heilongjiang Siberian Tiger Park HarbinHeilongjiang 150000China Jinlin Provincial Academy of Forestry Science ChangchunJilin 130033China China National GeneBank BGI ResearchShenzhenGuangdong 518120China Guangdong Provincial Key Laboratory of Genome Read and Write BGI ResearchShenzhenGuangdong 518083China BGI Life Science Joint Research Center Northeast Forestry UniversityHarbinHeilongjiang 150040China Feline Research Center of National Forestry and Grassland Administration College of Wildlife and Protected AreaNortheast Forestry UniversityHarbinHeilongjiang 150040China National Forestry and Grassland Administration Research Center of Engineering Technology for Wildlife Conservation and Utilization HarbinHeilongjiang 150040China

DEAR EDITOR,Big cats,such as Amur tigers(Panthera tigris altaica)and Amur leopards(*** orientalis),are apex predator and have evolved specialized traits for hunting and carnivory(Moya et al.,2022),thus playing a crucial role in maintaining biodiversity and ecosystem integrity by regulating prey-predator ***,human-induced pressures,habitat fragmentation,and environmental alterations have restricted these species in small and isolated ***,all extant big cats are categorized as endangered or threatened according to their conservation *** tigers and Amur leopards share overlapping geographic ranges,habitats,and certain prey species in the forests of Northeast Asia(Jiang et al.,2015).To reduce interspecies conflict,these carnivores exhibit differentiated dietary and temporal *** tigers predominantly prey on large ungulates,while Amur leopards hunt small to medium-sized animals(Sugimoto et al.,2016).Additionally,they occupy different temporal niches,with tigers being active at night and leopards more active during the *** spatial and temporal niche partitioning,interspecific competition between these two species is ***,benefiting from their greater size,have a competitive advantage over leopards,which can manifest in occasional leopard predation by tigers and declines in leopard populations with increasing tiger density(Jiang et al.,2015).Tigers also displace leopards from marginal habitats in nature reserves where they coexist.

关键词： habitat Panthera resolved

Jovian Planet Influence on the Forcing of Sunspot Cycles

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World Journal of Condensed Matter Physics 2024年第1期14卷 1-9页

作者： Fred J. Cadieu Physics department Queens College of CUNY New York USA

The history of our solar system has been greatly influenced by the fact that there is a large gas giant planet, Jupiter that has a nearly circular orbit. This has allowed relics of the early solar system formation to still be observable today. Since Jupiter orbits the Sun with a period of approximately 12 years, it has always been thought that this could be connected to the nearly 11-year periodic peak in the number of sunspots observed. In this paper, the Sun and planets are considered to be moving about a center of mass point as the different planets orbit the Sun. This is the action of gravity that holds the solar system together. The center of mass for the Jupiter-Sun system actually lies outside the Sun. The four gas giant planets dominate such effects and the four gas giant Jovian planets can be projected together to determine an effective distance from the Sun’s center. Taken together these effects do seem to function as a sunspot forcing factor with a periodicity very close to 11 years. These predictions are made without consideration of any details of what is happening in the interior of the Sun. From these estimates, sunspot cycle 25 will be expected to peak in about September-October of 2025. Sunspot cycle 26 should peak in the year March of 2037.

关键词： Sun Cycles Solar System Formation Jupiter

Multi-systemic melioidosis

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World Journal of Clinical Cases 2024年第28期12卷 6151-6154页

作者： Basavraj S Nagoba Shree V Dhotre Abhijit S Rayate Sachin S Mumbre Pradnya S Dhotre department of Microbiology Maharashtra Institute of Medical Sciences and Research(Medical College)Latur 413531India department of Microbiology Ashwini Rural Medical CollegeSolapur 413001India department of Surgery Maharashtra Institute of Medical Sciences and Research(Medical College)Latur 413531India department of Community Medicine Ashwini Rural Medical CollegeSolapur 413006India department of Biochemistry Ashwini Rural Medical CollegeSolapur 413001India

This editorial is a commentary on the article by Ni et al,which was published in the World Journal of Clinical *** article discusses the diagnostic and therapeutic challenges of melioidosis caused by Burkholderia *** case study highlights a rare instance of multisystemic melioidosis in a female patient who did not have a travel history,emphasizing the significance of recognizing this condition in non-endemic *** complexities and therapeutic strategies are addressed,emphasizing the need for heightened clinical suspicion,comprehensive evaluation,and multidisciplinary *** editorial delves into the clinical presentation,diagnostic dilemmas,therapeutic approaches,and their implications for patient care in managing multi-systemic melioidosis.

关键词： Melioidosis Burkholderia pseudomallei Multi-systemic Diagnosis Treatment

Heterogeneity in the risk of incident liver cirrhosis driven by PNPLA3 genotype and diabetes among different populations

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Hepatobiliary Surgery and Nutrition 2024年第1期13卷 115-118页

作者： Bo Kyung Koo Dong Hyeon Lee Jeong Hwan Park Won Kim Division of Endocrinology Department of Internal MedicineBoramae Medical CenterSeoulRepublic of Korea department of Internal Medicine Seoul National University College of MedicineSeoulRepublic of Korea Division of Gastroenterology and Hepatology Department of Internal MedicineBoramae Medical CenterSeoulRepublic of Korea department of Pathology Boramae Medical CenterSeoulRepublic of Korea

Advanced fibrosis determines the prognosis of nonalcoholic fatty liver disease(NAFLD);therefore,accurate risk-prediction for advanced fibrosis is fundamental in the management of NAFLD(1).Targeted screening for advanced fibrosis in high-risk populations,such as those with type 2 diabetes,obesity with metabolic complications,a family history of cirrhosis,or significant alcohol use is recommended for implementing early intervention to prevent future adverse hepatic outcomes of NAFLD(2,3).Non-invasive tests including fibrosis-4 index(FIB-4)and liver stiffness measurement(LSM)are recommended to identify individuals at a higher risk of liver-related events(1,2).In addition to clinical classifications,such as FIB-4;genetic information provides further stratification for liver-related outcomes(4).

关键词： Nonalcoholic fatty liver disease(NAFLD) cirrhosis PNPLA3-rs738409

Malignant triton tumor in the abdominal wall:A case report

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World Journal of Clinical Cases 2024年第8期12卷 1467-1473页

作者： Ho Jik Yang Donghyun Kim Won Suk Lee Sang-Ha Oh department of Plastic and Reconstructive Surgery Chungnam National University Sejong HospitalSejong 30099South Korea department of Plastic and Reconstructive Surgery Chungnam National University HospitalDaejeon 35015South Korea department of Emergency Eulji University HospitalDaejeon 35233South Korea department of Plastic and Reconstructive Surgery Chungnam National University College of MedicineDaejeon 35015South Korea

BACKGROUND Malignant triton tumors(MTTs)comprise a subgroup of malignant peripheral nerve sheath tumors(MPNSTs)that exhibits rhabdomyosarcomatous differen-tiation and follow an aggressive *** are primarily located along peripheral *** of MTTs in the abdominal wall have not been *** has a poorer prognosis than classic MPNSTs,and accurate diagnosis necessitates a keen understanding of the clinical history and knowledge of its differential diagnosis *** for MTTs mirrors that for MPNSTs and is predominantly *** SUMMARY A 49-year-old woman presented with a subcutaneous mass in her lower abdo-minal wall and a pre-existing surgical scar that had grown slowly over 3-4 months before the *** had previously undergone radical hysterectomy and concurrent chemo-radiotherapy for cervical cancer approximately 5 years prior to the *** computed tomography(CT)showed a 1.3 cm midline mass in the lower abdomen with infiltration into the rectus abdominis *** was no sign of metastasis(T1N0M0).An incisional biopsy identified sporadic MTT of the lower abdomen.A comprehensive surgical excision with a 3 cm margin inclusive of the peritoneum was ***-quently,the general surgeon utilized an approach akin to the open peritoneal onlay mesh *** patient underwent additional treatment with an excision shaped as a mini-abdominoplasty for the skin *** complications arose,and annual follow-up CTs did not show signs of recurrence or *** An abdominal MTT was efficaciously treated with extensive excision and abdominal wall reconstruction,eliminating the need for postoperative radiotherapy.

关键词： Malignant triton tumor Abdominal wall Surgical excision Reconstruction Case report

A CombustionModel for Explosive Charge Affected by a Bottom Gap in the Launch Environment

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Computer Modeling in Engineering & Sciences 2024年第2期138卷 1207-1236页

作者： ShiboWu Weidong Chen Jingxin Ma Lan Liu Shengzhuo Lu Honglin Meng Xiquan Song college of Aerospace and Civil Engineering Harbin Engineering UniversityHarbin150001China General department of Experimental Technology Beijing Institute of Structure and Environment EngineeringBeijing100076China department of Economics Kunlun Energy Holding Company LimitedBeijing100101China

Launch safety of explosive charges has become an urgent problem to be solved by all countries in the world aslaunch situation of ammunition becomes ***, the existing numericalmodels have differentdefects. This paper formulates an efficient computational model of the combustion of an explosive charge affectedby a bottom gap in the launch environment in the context of the material point method. The current temperatureis computed accurately from the heat balance equation, and different physical states of the explosive charges areconsidered through various equations of state. Microcracks in the explosive charges are described with respectto the viscoelastic statistical crackmechanics (Visco–SCRAM) model. Themethod for calculating the temperatureat the bottomof the explosive charge with respect to the bottomgap is described. Based on this combustionmodel,the temperature history of a Composition B (COMB) explosive charge in the presence of a bottom gap is obtainedduring the launch process of a 155-mm artillery. The simulation results show that the bottom gap thickness shouldbe no greater than 0.039 cm to ensure the safety of the COM B explosive charge in the launch environment. Thisconclusion is consistent with previous results and verifies the correctness of the proposed model. Ultimately, thispaper derives amathematical expression for themaximumtemperature of the COMB explosive chargewith respectto the bottomgap thickness (over the range of 0.00–0.039 cm), and establishes a quantitative evaluationmethod forthe launch safety of explosive *** research results provide some guidance for the assessment and detectionof explosive charge safety in complex launch environments.

关键词： Combustion model explosive charge safety launch environment bottom gap temperature