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Age-specific differences in the association between prediabetes and cardiovascular diseases in China:A national cross-sectional study

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World Journal of Diabetes 2024年第2期15卷 240-250页

作者： Shuo Xie Li-Ping Yu Fei Chen Yao Wang Rui-Fen Deng Xue-Lian Zhang Bo Zhang department of Endocrinology Chinese Academy of Medical SciencesPeking Union Medical CollegeBeijing 100730China department of Endocrinology China-Japan Friendship HospitalBeijing 100029China

BACKGROUND Cardiovascular disease(CVD)is a leading cause of morbidity and mortality worldwide,the global burden of which is *** is still unclear the extent to which prediabetes contributes to the risk of CVD in various age brackets among *** develop a focused screening plan and treatment for Chinese adults with prediabetes,it is crucial to identify variations in the connection between prediabetes and the risk of CVD based on *** To examine the clinical features of prediabetes and identify risk factors for CVD in different age groups in *** The cross-sectional study involved a total of 46239 participants from June 2007 through May 2008.A thorough evaluation was *** with prediabetes were categorized into two groups based on *** atherosclerotic CVD risk prediction model was employed to evaluate the risk of developing CVD over 10 *** forest was established in both age *** Additive exPlanation method prioritized the importance of features from the perspective of assessment *** In total,6948 people were diagnosed with prediabetes in this *** prediabetes,prevalences of CVD were 5(0.29%)in the younger group and 148(2.85%)in the older ***,11.11%of the younger group and 29.59% of the older group were intermediate/high-risk of CVD for prediabetes without CVD based on the Prediction for ASCVD Risk in China equation in ten *** the younger age group,the 10-year risk of CVD was found to be more closely linked to family history of CVD rather than lifestyle,whereas in the older age group,resident status was more closely *** The susceptibility to CVD is age-specific in newly diagnosed *** is necessary to develop targeted approaches for the prevention and management of CVD in adults across various age brackets.

关键词： Age Cardiovascular diseases Prediabetes Risk factors Differences

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Uncovering the functional basis of mantids that resemble plants

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Science China(Life Sciences) 2024年第1期67卷 215-216页

作者： Wei Zhang David JLohman State Key Laboratory of Protein and Plant Gene Research School of Life SciencesPeking UniversityBeijing 100871China Peking-Tsinghua Center for Life Sciences Academy for Advanced Interdisciplinary StudiesPeking UniversityBeijing 100871China Biology department City College of New YorkCity University of New YorkNew York 10031 USA PhD Program in Biology City University of New YorkNew York 10016 USA Entomology Section National Museum of Natural HistoryManila 1000Philippines

Convergent evolution frequently causes one species to look like another to increase its ***“adaptive resemblance”takes many forms:edible species mimic noxious ones to avoid predation;camouflaged patterns allow an organism to blend into its environment;and being mistaken for an inedible object allows a prey species to masquerade as a twig or dead *** resemblance is relatively common in insects,which comprise around 60%of known species.

关键词： species functional mimic

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Quantitative analysis of the morphing wing mechanism of raptors:IMMU-based motion capture system and its application on gestures of a Falco peregrinus

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Chinese Physics B 2024年第1期33卷 734-742页

作者：唐迪朱力文施文熙刘大伟杨茵姚国荣严森祥范忠勇陆祎玮王思宇 college of Mechanical Engineering Zhejiang University of TechnologyHangzhou 310014China High Speed Aerodynamic Institute China Aerodynamics Research and Development CenterMianyang 621000China department of Radiation Oncology The First Affiliated HospitalZhejiang UniversityHangzhou 310009China Zhejiang Museum of Natural history Hangzhou 310014China

This paper presented a novel tinny motion capture system for measuring bird posture based on inertial and magnetic measurement units that are made up of micromachined gyroscopes, accelerometers, and magnetometers. Multiple quaternion-based extended Kalman filters were implemented to estimate the absolute orientations to achieve high *** the guidance of ornithology experts, the extending/contracting motions and flapping cycles were recorded using the developed motion capture system, and the orientation of each bone was also analyzed. The captured flapping gesture of the Falco peregrinus is crucial to the motion database of raptors as well as the bionic design.

关键词： Falco peregrinus IMMU-based motion capture system flapping gesture

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Asexual Reproduction of Aurelia coerulea Polyps in situ on Settling Plates in Jiaozhou Bay,China

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Journal of Ocean University of China 2024年第5期23卷 1371-1380页

作者： MI Tiezhu ZHU Jianbin ZHEN Yu WANG Guoshan WANG Jianyan Key Laboratory of Marine Environment and Ecology Ministry of EducationCollege of Environmental Science and EngineeringOcean University of ChinaQingdao 266100China Laboratory for Marine Ecology and Environmental Science Qingdao Marine Science and Technology CenterQingdao 266237China Frontiers Science Center for Deep Ocean Multispheres and Earth System Ocean University of ChinaQingdao 266100China National Marine Hazard Mitigation Service Ministry of Natural ResourcesBeijing 100194China department of Life Sciences National Natural History Museum of ChinaBeijing 100050China

Jellyfish blooms are increasingly prevalent coastal phenomena,with Aurelia coerulea being a significant *** complex life history of jellyfish,featuring a sessile polyp stage,is a key factor in bloom formation,yet it is challenging to study in the *** study aimed to describe the asexual reproduction of *** polyps in Jiaozhou Bay,China,and to assess their ability to form sedentary colonies and their relationship with environmental *** settling plates,we observed polyps in situ and documented three asexual reproduction modes:budding,strobilation,and podocyst *** parameters including temperature,salinity,dissolved oxygen(DO),chlorophyll a(Chl a),and the biomass of phytoplankton and zooplankton were *** was the predominant reproductive method,featuring stolon budding in autumn and direct budding during the winter and spring *** took place in the colder months,releasing ephyrae between April and *** abundance was positively correlated with seawater temperature and negatively correlated with DO *** at 1.0 m depth showed higher survivorship and proliferation over 8 months,whereas those at 2.0 m depth experienced a steady decline and died within 4 *** study enhances our understanding of the life cycle and asexual reproduction strategies of *** polyps in the field,with implications for predicting and managing jellyfish *** findings underscore the importance of temperature and DO in polyp survival and suggest that initial polyp population proliferation is crucial for long-term survival.

关键词： jellyfish bloom polyps budding strobilation asexual reproduction

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An Integral Method for Solving Dynamic Equations with Fluid–Solid Coupling

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Acta Mechanica Solida Sinica 2024年第1期37卷 99-108页

作者： Xin Zhang Jie Liu Pu Xue Shuowen Yan Yahao Xu M.S.Zahran School of Aeronautics Northwestern Polytechnical UniversityXi'an 710072China School of Mechatronical Engineering Beijing Institute of TechnologyBeijing 100081China department of Civil Engineering Military Technical CollegeCairo 11435Egypt

In this work,a new methodology is presented to mainly solve the fluid–solid interaction(FSI)*** methodology combines the advantages of the Newmark precise integral method(NPIM)and the dual neural network(DNN)*** NPIM is employed to modify the exponential matrix and loading vector based on the DNN integral *** involves incorporating the basic assumption of the Newmark-βmethod into the dynamic equation and eliminating the acceleration term from the dynamic equilibrium *** a result,the equation is reduced to a first-order linear equation ***,the PIM is applied to integrate the system step by step within the *** DNN method is adopted to solve the inhomogeneous term through fitting the integrand and the original function with a pair of neural networks,and the integral term is solved using the Newton–Leibniz *** examples demonstrate that the proposed methodology significantly improves computing efficiency and provides sufficient precision compared to the DNN *** is particularly evident when analyzing large-scale structures under blast loading conditions.

关键词： Newmark precise integral method(NPIM) Dual neural networks(DNN) Fluid-solid interaction(FSI) Dynamic time-history analysis Blast loading

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The history of Controlling and Treating Infectious Diseases in Ancient China

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Current Medical Science 2024年第1期44卷 64-70页

作者： Cui-ling LIU Tao ZHOU Liang-bin CHENG David FISHER Khrystyna PRONYUK Erkin MUSABAEV Yi-ping DANG Lei ZHAO department of Infectious Diseases Union HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhan 430022China department of Gastroenterology and Hepatology Huanggang Hospital of Traditional Chinese MedicineHubei University of Chinese MedicineHuanggang 438000China Clinical college of Traditional Chinese Medicine Hubei University of Chinese MedicineWuhan 430065China department of Liver Diseases Hubei Hospital of Traditional Chinese MedicineWuhan 430061China department of Medical Biosciences Faculty of Natural SciencesUniversity of the Western CapeBellvilleCape Town 7535South Africa department of Infectious Diseases Bogomolets National Medical UniversityKyiv 02132Ukraine The Research Institute of Virology Ministry of HealthTashkent 100122Uzbekistan department of Vascular Surgery Union HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhan 430022China

Infectious diseases are the common enemies of *** the course of historical development,they persistently threaten human health and *** today,despite the developments in medical science,we cannot escape the fear and suffering caused by infectious *** in ancient or modern times,the source of infection,route of transmission,and a susceptible population are the three key conditions for the prevalence and spread of infectious *** factors closely related to these three conditions can affect the prevalence of infectious *** is one of the cradles of world *** ancient people accumulated a great deal of experience and lessons in the long struggle against infectious *** the face of the current threat posed by widespread infectious disease,it is imperative to review and summarize ancient Chinese ideas and health policies on epidemic prevention and control to inspire contemporary efforts in the prevention and control of infectious *** combination of prevention-oriented epidemic prevention ideology and traditional medicine provides valuable insights,especially for impoverished and medically underserved regions.

关键词： infectious diseases Chinese medicine public health historical review

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TGF-βsignaling in health,disease,and therapeutics

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Signal Transduction and Targeted Therapy 2024年第4期9卷 1466-1505页

作者： Ziqin Deng Tao Fan Chu Xiao He Tian Yujia Zheng Chunxiang Li Jie He department of Thoracic Surgery National Cancer Center/National Clinical Research Center for Cancer/Cancer HospitalChinese Academy of Medical Sciences and Peking Union Medical CollegeBeijing 100021China

ransforming growth factor(TGF)-βis a multifunctional cytokine expressed by almost every tissue and cell *** signal transduction of TGF-βcan stimulate diverse cellular responses and is particularly critical to embryonic development,wound healing,tissue homeostasis,and immune homeostasis in *** dysfunction of TGF-βcan play key roles in many diseases,and numerous targeted therapies have been developed to rectify its pathogenic *** the past decades,a large number of studies on TGF-βsignaling have been carried out,covering a broad spectrum of topics in health,disease,and ***,a comprehensive overview of TGF-βsignaling is required for a general picture of the studies in this *** this review,we retrace the research history of TGF-βand introduce the molecular mechanisms regarding its biosynthesis,activation,and signal *** also provide deep insights into the functions of TGF-βsignaling in physiological conditions as well as in pathological ***-β-targeting therapies which have brought fresh hope to the treatment of relevant diseases are *** the summary of previous knowledge and recent updates,this review aims to provide a systematic understanding of TGF-βsignaling and to attract more attention and interest to this research area.

关键词： homeostasis healing wound

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Interaction between systemic iron parameters and left ventricular structure and function in the preserved ejection fraction population:a two-sample bidirectional Mendelian randomization study

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Journal of Geriatric Cardiology 2024年第1期21卷 64-80页

作者： Xiong-Bin MA Yong-Ming LIU Yan-Lin LV Lin QIAN The First Clinical Medical college of Lanzhou University LanzhouGansuChina Geriatric Cardiovascular department and Gansu Clinical Research Center for Geriatric Diseases First Hospital of Lanzhou UniversityGansuChina

BACKGROUND Left ventricular(LV)remodeling and diastolic function in people with heart failure(HF)are correlated with iron status;however,the causality is *** Mendelian randomization(MR)study investigated the bidirectional causal relationship between systemic iron parameters and LV structure and function in a preserved ejection fraction *** Transferrin saturation(TSAT),total iron binding capacity(TIBC),and serum iron and ferritin levels were extracted as instrumental variables for iron parameters from meta-analyses of public genome-wide association *** without myocardial infarction history,HF,or LV ejection fraction(LVEF)<50%(n=16,923)in the UK Biobank Cardiovascular Magnetic Resonance Imaging Study constituted the outcome *** dataset included LV end-diastolic volume,LV endsystolic volume,LV mass(LVM),and LVM-to-end-diastolic volume ratio(LVMVR).We used a two-sample bidirectional MR study with inverse variance weighting(IVW)as the primary analysis method and estimation methods using different algorithms to improve the robustness of the *** In the IVW analysis,one standard deviation(SD)increased in TSAT significantly correlated with decreased LVMVR(β=-0.1365;95%confidence interval[CI]:-0.2092 to-0.0638;P=0.0002)after Bonferroni ***,no significant relationships were observed between other iron and LV *** Bonferroni correction,reverse MR analysis showed that one SD increase in LVEF significantly correlated with decreased TSAT(β=-0.0699;95%CI:-0.1087 to-0.0311;P=0.0004).No heterogeneity or pleiotropic effects evidence was observed in the *** We demonstrated a causal relationship between TSAT and LV remodeling and function in a preserved ejection fraction population.

关键词： fraction function parameters

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Writing the Taiping War into the history of the Southern Ming： Xu Zi, the Militia of Luhe, and the Annals of a Fallen State

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Frontiers of history in China 2018年第2期13卷 227-258页

作者： Chuck Wooldridge history department of lehman college 250 Bedford Park Blvd West Bronx NY 10468 USA

Between 1853 and 1858, the militia and hired braves of Luhe county, Jiangsu, distinguished themselves by successfully defending against Taiping attack when surrounding counties and cities all fell. The historian Xu Zi （1810-62） served as a militia leader, commanding a company of troops and working to raise funds to pay for provisions. At the same time, he was writing his history of the Southern Ming Courts： Annals of a Fallen State, With Appended Annotations （Xiaotian jinian fukao）. In his history, Xu Zi included anecdotes of his wartime experiences, writing the Taiping War into the history of the Southern Ming. What does history do？ Xu Zi hoped it could help establish and maintain the coherence of the forces fighting the Taiping. To that end, he presented exemplary figures from the past for people of his own time to emulate, and he narrated those stories to his fellow soldiers. At the same time, his work suggests that the practices of the historian--including investigation of sources, expressions of emotion, and evaluation of policy--could provide avenues for defeating the Taiping. By writing himself into his history of the Southern Ming, he showed how the past could become a tool of war.

关键词： Xu Zi Wen Shaoyuan Southern Ming militia Taiping lijin Luhe

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A new titanosaurian sauropod from the Upper Cretaceous of Jiangxi Province, southern China

自然遗产与文博研究

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自然遗产与文博研究 2024年 143-177页

作者： Mo Jinyou Fu Qiongyao Yu Yilun Xu Xing Geological department Natural history Museum of Guangxi Key Laboratory of Vertebrate Evolution and Human Origins of Chinese Academy of SciencesInstitute of Vertebrate Paleontology and Paleoanthropology Chinese Academy of Sciences Centre for Vertebrate Evolutionary Biology Yunnan University college of Paleontology Paleontological Museum of Liaoning Shenyang Normal University

Jiangxititan ganzhouensis gen. et sp. nov. is a new titanosaurian sauropod recovered from the Upper Cretaceous(Maastrichtian) Nanxiong Formation of Jiangxi Province, southern China. It is characterised by:(1) posterior cervical and anterior dorsal centra strongly compressed dorsoventrally;(2) accessory horizontal laminae present within the anterior dorsal pleurocoels;(3) posterior cervical and anterior dorsal neural arches low;(4) posterior cervical and anterior dorsal neural spines deeply bifurcated and widely separated;(5) inverted'V'lamina formed by the left and right medial spinoprezygapophyseal laminae present at the anterior margin of the bifid point in posteriormost cervical and anteriormost dorsal neural spines;(6) triangular fossa formed by the metapophysis, medial and lateral spinoprezygapophyseal laminae present at the anterior margins of the posteriormost cervical and anteriormost dorsal neural spines;(7) postzygapophyses in the posterior cervical vertebrae fan-shaped;(8) medial and lateral spinopostzygapophyseal laminae present in the anterior dorsal vertebrae and;(9) anterior dorsal rib short and gracile. Our phylogenetic analysis places Jiangxititan within the deeply-nested titanosauriform clade Lognkosauria and the sympatric Gannansaurus in a much earlier-diverging lineage. This new discovery thus demonstrates the presence of both early-diverging and late-diverging titanosauriform sauropods in the Late Cretaceous Ganzhou dinosaur fauna.

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