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Population-based X-ray gastric cancer screening in hiroshima prefecture, Japan

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World Journal of Clinical Oncology 2024年第2期15卷 271-281页

作者： Nhu Thi Hanh Vu Yuji Urabe Duc Trong Quach Shiro Oka Toru Hiyama Department of Internal Medicine University of Medicine and Pharmacy at Ho Chi Minh CityHo Chi Minh 700000Viet Nam Department of Endoscopy Hiroshima University HospitalHiroshima 734-8551Japan Department of Gastrointestinal Endoscopy and Medicine Hiroshima University HospitalHiroshima 734-8551Japan Department of Gastroenterology Hiroshima University HospitalHiroshima 734-8551Japan Health Service Center Hiroshima UniversityHigashihiroshima 739-8514Japan

BACKGROUND X-ray gastric cancer(GC)screening has been shown to decrease ***-based X-ray GC screening has been performed in hiroshima Prefe-cture,Japan,since 1983 but time trends and the efficacy of the method over 39 years have not been *** This was a population-based retrospective *** data were derived from aggregated data of the hiroshima Regional Health Medical Promotion Organization,including the number and rate of participants and those requiring esophagogastroduodenoscopies(EGDs),the number and rate of participants diagnosed as having GC,and the positive predictive value of the abnormal findings detected by X-ray and confirmed by *** number and rate of esophageal cancers were also ***,the cost of detecting one GC was *** The number of participants has decreased during the last four decades,from 39925 in 1983 to 12923 in *** rate of those requiring EGDs decreased significantly in recent years(Phiroshima has been efficient,but one challenge is the *** cancers may also need to be considered because they have gradually increased in recent years.

关键词： Population Retrospective studies X-ray Gastric cancer Screening

Do changes in intracoronary pressure aid coronary spasm diagnosis using the spasm provocation test?

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World Journal of Cardiology 2024年第1期16卷 16-26页

作者： Hiroki Teragawa Chikage Oshita Yuko Uchimura Department of Cardiovascular Medicine JR Hiroshima HospitalHiroshima 732-0057Japan

BACKGROUND Although the spasm provocation test(SPT)can diagnose coronary spasms,it would be helpful if it could also predict their *** To investigate whether coronary spasms can be predicted using changes in intracoronary artery pressure measured using a pressure wire during the *** Seventy patients underwent SPTs with pressure-wire measurement of intracoronary artery *** each SPT,the pressure wire was advanced into the distal portion of the right coronary artery(RCA)and left anterior descending coronary artery,and the ratio of intracoronary pressure to aortic pressure(Pd/Pa)was *** spasm was defined as an arterial narrowing of>90%in response to the administration of acetylcholine(ACh),with chest symptoms and/or ischemic electrocardiographic *** was administered to the RCA at low,moderate,or high doses of 20,50,or 80μg,respectively,and to the left coronary artery(LCA)at low,moderate,or high doses of 50,100,or 200μg,*** arteries with coronary spasms at low doses of ACh were defined as group L,and those with coronary spasms at moderate or high doses were defined as group *** who did not occur coronary spasms at any ACh dose were designated as group *** Among the 132 coronary arteries assessed using a pressure wire,there were 49 in group N,25 in group L,and 58 in group *** Pd/Pa was the lowest in group L(P=0.001).The decrease in the Pd/Pa between baseline to low doses of ACh was lower in group MH than in group N(P<0.001).A receiver-operating characteristics analysis showed that the cutoff baseline Pd/Pa value for predicting group L was 0.95,with a sensitivity of 0.600(15/25)and a specificity of 0.713(76/107)and that the cutoff value of Pd/Pa from baseline to low doses of ACh for predicting group MH was−0.04,with a sensitivity of 0.741(43/58)and a specificity of 0.694(34/49).CONCLUSION These findings suggest that indices of intracoronary pressure during SPT may be useful means for

关键词： Acetylcholine Coronary spasm Intracoronary pressure Pressure wire Spasm provocation test Vasospastic angina

High-grade pancreatic intraepithelial neoplasia diagnosed based on changes in magnetic resonance cholangiopancreatography findings:A case report

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World Journal of Clinical Cases 2024年第8期12卷 1487-1496页

作者： Nao Furuya Atsushi Yamaguchi Naohiro Kato Syuhei Sugata Takuro Hamada Takeshi Mizumoto Yuzuru Tamaru Ryusaku Kusunoki Toshio Kuwai Hirotaka Kouno Kazuya Kuraoka Yoshiyuki Shibata Sho Tazuma Takeshi Sudo Hiroshi Kohno Shiro Oka Department of Gastroenterology National Hospital Organization Kure Medical Center and Chugoku Cancer CenterKure 737-0023HiroshimaJapan Department of Gastroenterology Hiroshima University HospitalHiroshima 734-8551HiroshimaJapan Department of Pathology National Hospital Organization Kure Medical Center and Chugoku Cancer CenterKure 737-0023HiroshimaJapan Department of Surgery National Hospital Organization Kure Medical Center and Chugoku Cancer CenterKure 737-0023HiroshimaJapan

BACKGROUND High-grade pancreatic intraepithelial neoplasia(PanIN)exhibits no mass and is not detected by any examination ***,it can be diagnosed by pancreatic juice cytology from indirect *** previous cases were diagnosed based on findings of a focal stricture of the main pancreatic duct(MPD)and caudal MPD dilatation and subsequent pancreatic juice cytology using endoscopic retrograde cholangiopancreatography(ERCP).We experienced a case of high-grade PanIN with an unclear MPD over a 20-mm range,but without caudal MPD dilatation on magnetic resonance cholangiopancreatography(MRCP).CASE SUMMARY A 60-year-old female patient underwent computed tomography for a follow-up of uterine cancer post-excision,which revealed pancreatic *** revealed an unclear MPD of the pancreatic body at a 20-mm length without caudal MPD ***,course observation was *** 24 mo,MRCP revealed an increased caudal MPD caliber and a larger pancreatic *** performed ERCP and detected atypical cells suspected of adenocarcinoma by serial pancreatic juice aspiration cytology *** performed a distal pancreatectomy and obtained a histopathological diagnosis of high-grade *** parenchyma invasion was not observed,and curative resection was *** High-grade Pan-IN may cause MPD narrowing in a long range without caudal MPD dilatation.

关键词： Pancreatic cancer Pancreatic intraepithelial neoplasm High-grade pancreatic intraepithelial neoplasm Magnetic resonance cholangiopancreatography Carcinoma in situ Case report

High critical current density in Li_(6.4)La_(3)Zr_(1.4)Ta_(0.6)O_(12) electrolyte via interfacial engineering with complex hydride

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Rare Metals 2024年第2期43卷 692-701页

作者： Ying-Tong Lv Teng-Fei Zhang Zhao-Tong Hu Guang-Lin Xia Ze-Ya Huang Zhen-Hua Liu Li-Hua Que Cai-Ting Yuan Fang-Qin Guo Takayuki Ichikawa Xue-Bin Yu College of Materials Science and Technology Nanjing University of Aeronautics and AstronauticsNanjing210016China Centre for Hydrogenergy College of Materials Science and TechnologyNanjing University of Aeronautics and AstronauticsNanjing210016China Department of Materials Science Fudan UniversityShanghai200433China Graduate School of Advanced Science and Engineering Hiroshima University1-4-1 KagamiyamaHigashi-Hiroshima739-8527Japan

Garnet-type solid-state batteries(SSBs)are considered to be one of the most promising candidates to realize next-generation lithium metal batteries with high energy density and ***,the dendrite-induced short-circuit and the poor interfacial contact impeded the practical ***,interface engineering to achieve low interfacial resistance without high temperature calcination was developed,which Li_(6.4)La_(3)Zr_(1.4)Ta_(0.6)O_(12)(LLZTO)was simply coated with complex hydride(Li_(4)(BH_(4))_(3)I(3L1L))in various mass ratios n(Li_(4)(BH_(4))_(3)I)-(100−n)LLZTO(10≤n≤40).The interfacial conductivity increases by more than three orders of magnitude from 8.29×10^(−6)S·cm^(−1)to 1.10×10^(−2)S·cm^(−1).Symmetric Li cells exhibit a high critical current density(CCD)of 4.0 mA·cm^(−2) and an excellent cycling stability for 200 h at 4.0 mA·cm^(−2).SSBs with polymeric sulfur-polyacrylonitrile(SPAN)cathode achieve a high discharge capacity of 1149 mAh·g^(−1) with a capacity retention of 91%after 100 cycles(0.2 C).This attempt guides a simple yet efficient strategy for obtaining a stable Li/LLZTO interface,which would promote the development of solid-state batteries.

关键词： Hydrides Li_(6.4)La_(3)Zr_(1.4)Ta_(0.6)O_(12)(LLZTO) Critical current density Solid-state electrolytes(SSEs) Lithium-sulfur batteries

Ripple Knowledge Graph Convolutional Networks for Recommendation Systems

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Machine Intelligence Research 2024年第3期21卷 481-494页

作者： Chen Li Yang Cao Ye Zhu Debo Cheng Chengyuan Li Yasuhiko Morimoto Graduate School of Informatics Nagoya UniversityChikusaNagoya 464-8602Japan Centre for Cyber Resilience and Trust Deakin UniversityBurwood 3125Australia Science TechnologyEngineering and Mathematics(STEM)University of South AustraliaAdelaide 5000Australia Graduate School of Engineering Hiroshima UniversityHigashi-hiroshima 10587Japan

Using knowledge graphs to assist deep learning models in making recommendation decisions has recently been proven to effectively improve the model′s interpretability and *** paper introduces an end-to-end deep learning model,named representation-enhanced knowledge graph convolutional networks(RKGCN),which dynamically analyses each user′s preferences and makes a recommendation of suitable *** combines knowledge graphs on both the item side and user side to enrich their representations to maximize the utilization of the abundant information in knowledge *** is able to offer more personalized and relevant recommendations in three different *** experimental results show the superior effectiveness of our model over 5 baseline models on three real-world datasets including movies,books,and music.

关键词： Deep learning recommendation systems knowledge graph graph convolutional networks(GCNs) graph neural networks(GNNs)

A dynamic speed guidance method at on-ramp merging areas of urban expressway considering driving styles

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Frontiers of Engineering Management 2024年第1期11卷 92-106页

作者： Haoran LI Yunpeng LU Yaqiu LI Junyi ZHANG School of Automobile and Traffic Engineering Wuhan University of Science and TechnologyWuhan 430065China Suzhou Automotive Research Institute Tsinghua UniversitySuzhou 215134China School of Transportation Southeast UniversityNanjing 211189China Graduate School of Advanced Science and Engineering Hiroshima UniversityHigashi Hiroshima 739-8529Japan

Dynamic speed guidance for vehicles in on-ramp merging zones is instrumental in alleviating traffic congestion on urban *** enhance compliance with recommended speeds,the development of a dynamic speed-guidance mechanism that accounts for heterogeneity in human driving styles is *** intelligent connected technologies that provide real-time vehicular data in these merging locales,this study proposes such a guidance ***,we integrate a multi-agent consensus algorithm into a multi-vehicle framework operating on both the mainline and the ramp,thereby facilitating harmonized speed and spacing ***,we conduct an analysis of the behavioral traits inherent to drivers of varied styles to refine speed planning in a more efficient and reliable ***,we investigate a closed-loop feedback approach for speed guidance that incorporates the driver’s execution rate,thereby enabling dynamic recalibration of advised speeds and ensuring fluid vehicular integration into the *** results substantiate that a dynamic speed guidance system incorporating driving styles offers effective support for human drivers in seamless mainline merging.

关键词： driving styles speed guidance driving safety assistance on-ramp merging

综合医院认知障碍患者护理困难量表的编制和信效度检验

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International Journal of Nursing Sciences 2024年第3期11卷 357-365,I0003,I0004页

作者：刘婷中谷久惠陈卉芳高囡 Graduate School of Biomedical and Health Sciences Hiroshima UniversityHiroshimaJapan School of Nursing Guangzhou Medical UniversityGuangzhouGuangdongChina Operating Room Hangzhou Hospital of Traditional Chinese MedicineHangzhouZhejiangChina hiroshima Red Cross Hospital&Atomic-bomb Survivors Hospital HiroshimaJapan

目的随着中国老龄化速度的加快,患有认知障碍的患者住院率逐渐上升。目前,针对中国综合医院认知障碍患者护理困难的研究相对有限。该研究编制了针对综合医院护士的认知障碍患者护理困难量表,并验证其效度和信度。方法以生物-心理-社会... 详细信息

目的随着中国老龄化速度的加快,患有认知障碍的患者住院率逐渐上升。目前,针对中国综合医院认知障碍患者护理困难的研究相对有限。该研究编制了针对综合医院护士的认知障碍患者护理困难量表,并验证其效度和信度。方法以生物-心理-社会医学理论模型为指导,通过文献查阅、定性访谈、专家咨询拟订初始量表。2021年9月至11月,对11所综合性医院的313名护士进行调查。采用项目分析、探索性因子分析、已知组别法和并存效度,验证量表的效度。采用Cronbach'sα系数和分半可靠性评估量表的信度。结果各条目内容效度指数(I-CVI)为0.833~1.00,总内容效度指数(S-CVI)为0.929。通过项目分析和探索性因子分析提取了21个项目,涉及4个因子。根据已知组别法,认知障碍护理经验丰富组和有认知障碍护理培训经历组的护理困难程度,显著低于经验较少组和未接受过培训组。综合医院认知障碍患者护理困难量表与护士工作压力源量表的相关系数为0.387,与认知障碍护理态度量表的相关系数为-0.239。各维度的Cronbach'sα系数为0.889~0.905,总的Cronbach'sα系数为0.959。各维度的折半系数为0.814~0.894,总体为0.911。结论该研究制订了综合医院认知障碍患者护理困难量表,并提取了4个因子,验证了该量表的信度和效度。该量表可用于评估综合医院认知障碍患者护理实践的难度,并可用于未来的研究以改善认知障碍患者的护理实践。

关键词：认知障碍综合医院护理实践难度老年人心理测试

The Effect of Umami Stimulation on Salivary Secretion Rate and Duration

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Health 2024年第1期16卷 52-59页

作者： Eri Sambuichi Rumi Nishimura Shiho Morishita Shigeru Watanabe Department of Oral Health Sciences School of Health Sciences Meikai University Urayasu Japan Department of Oral Epidemiology Graduate School of Biomedical and Health Sciences Hiroshima University Hiroshima Japan

Purpose: Umami reportedly promotes salivation. We aimed to investigate the effects of taste stimuli on slow and fast salivary secretion in humans using umami, sweet, and sour stimuli. Methods: Eight healthy women participated between 14:00 and 15:00, taking the circadian rhythm of salivary secretion into account. The types and concentrations of the taste solutions were glutamic acid (1.7 × 10−3 M), inosinic acid (9.8 × 10−3 M), and guanylic acid (9.8 × 10−3 M) for umami stimulation, citric acid (6.5 × 10−3 M) for acidity stimulation, and sucrose (1.6 × 10−2 M) for sweetness stimulation. First, the unstimulated salivary flow rate was measured. Then, 3 ml of a flavor solution was dropped under the tongue using a syringe. The saliva was expelled into an aluminum cup every minute and weighed. The first minute’s value minus 3 ml flavor solution was the stimulated salivary secretion rate produced by each flavor. The time-to-return to the initial unstimulated salivary flow rate was the duration of the stimulated saliva secretion rate. Results: The mean unstimulated salivary flow rate across participants was 0.64 ± 0.25 ml/min (range: 0.23 - 1.03 ml/min). The highest amount of saliva was induced by citric acid. There were significant differences between citric acid and the other flavor solutions (p < 0.05 for glutamic acid, inosinic acid, and sucrose;p < 0.01 for guanylic acid). There were no significant differences in duration of salivation between the flavor solutions. When the participants were divided into slow (0.45 ± 0.16 ml/min) and fast groups (0.83 ± 0.15 ml/min) based on their median resting salivary secretion rate, there were no significant differences between the two groups in the amount of saliva secreted at 1 minute after stimulation and the duration of the salivary secretion rate. Conclusion: Umami stimulation was effective in slowing salivary secretion and sustaining salivary secretion after stimulation.

关键词： Salivary Secretion Umami Flavor Oral Health Stimulated Salivary Secretion

Experimental study on slender buckling-restrained knee braces with round steel bar cores

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Frontiers of Structural and Civil Engineering 2023年第1期17卷 99-121页

作者： Togtokhbuyan MUNKHUNUR Hiroshi TAGAWA Xingchen CHEN Graduate School of Engineering Hiroshima UniversityHigashi-Hiroshima 739-8527Japan Graduate School of Advanced Science and Engineering Hiroshima UniversityHigashi-Hiroshima 739-8527Japan

This study aimed to investigate a novel slender buckling-restrained knee brace damper (BRKB) for welded and weld-free steel framing systems. The proposed BRKB adopts steel bar cores connected by a central coupler and restrained by tube buckling restrainers with a cover tube supporter. The advantages of the proposed damper include easy assembly compared to conventional buckling restrained braces, and high architectural flexibility for the retrofitting of large-span weld-free or welded steel moment-resisting systems. Specifically, by increasing the number of contraction allowances, undesirable failure mechanisms that are global instability and local buckling of the restrainer ends can be effectively suppressed because the more uniform plastic deformation of the core bar can be achieved longitudinally. In this study, displacement-controlled compression and cyclic loading tests were carried out to investigate the deformation capacities of the proposed BRKBs. Structural performance metrics associated with both loading tests, such as strength capacities, strains at the cover tubes and buckling restrainers, and hysteretic behaviors of the proposed damper under cyclic loads, were measured and discussed. Test results revealed that the geometrical characteristics of the cover tubes and adopted contraction allowances at the dampers play essential roles in their load-bearing capacities.

关键词： weld-free beam-to-column connections moment-resisting frame cyclic and compression loading tests buckling-restrained knee brace cover tube