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Fault Detection of Networked Control Systems Based on Optimal Robust Fault Detection Filter

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自动化学报 2008年第12期34卷 1534-1539页

作者： WANG Yong-Qiang YE Hao DING X. Steven WANG Gui-Zeng Department of Automation Tsinghua University Beijing 100084 P. R. China Institute for Automatic Control and Complex Systems University of Duisburg-Essen Duisburg 47057 Germany

有可能比一个采样时期大的随机、未知的导致网络的延期的联网的控制系统(NCS ) 的差错察觉在这份报纸被学习。首先，导致网络的延期引起的影响被转变成为错误建模组织，然后存在连续时间域基于引用，模型被扩大到分离时间领域并且适用... 详细信息

有可能比一个采样时期大的随机、未知的导致网络的延期的联网的控制系统(NCS ) 的差错察觉在这份报纸被学习。首先，导致网络的延期引起的影响被转变成为错误建模组织，然后存在连续时间域基于引用，模型被扩大到分离时间领域并且适用指责联网的控制系统的察觉的柔韧的差错察觉方法。建议方法能被 Matlab LMI 工具箱容易实现，并且它的表演被一个模拟例子最后评估。

关键词：检测方法网络控制系统最优鲁棒故障检测系统滤波器

Focus on LPA signaling:a promising therapeutic target to foster regeneration in immune-mediated neuropathies

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Neural Regeneration Research 2023年第12期18卷 2651-2652页

作者： Fabian Szepanowski Mark Stettner Department of Neurology and Center for Translational and Behavioral Neurosciences(C-TNBS) University Medicine EssenUniversity Duisburg EssenEssenGermany

Lysophospholipids are metabolites of glycerophospholipids and sphingolipids that are commonly found as lipid constituents of cell *** addition to their function as structural membrane components,certain members of the lysophospholipid family have considera ble cell signaling pro ***-1-phosphate(S1P) and lysophosphatidic acid(LPA)represent the two major bioactive members of the lysophospholipid family that address specific G-protein cou pled receptors.

关键词： lipids therapeutic Focus

Controversial: Early Innate Responses to Hepatitis B Virus Infection,an Explanation for Viral Persistence?

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Virologica Sinica 2021年第1期36卷 163-166页

作者： Ruth Broering Xufeng Luo Jia Liu Mengji Lu Department of Gastroenterology and Hepatology University Hospital EssenUniversity of Duisburg-Essen45147 EssenGermany Department of Infectious Diseases Union HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhan 430022China Institute of Virology University Hospital EssenUniversity of Duisburg-Essen45147 EssenGermany

Hepatitis B virus(HBV)infection is one of the most common causes for liver related morbidity and mortality *** fibrosis and cirrhosis occur in the course of chronic HBV infection,with the increasing risk to develop hepatocellular *** about 95%of adults’acute hepatitis B virus infection is self-limited,whereas in 90%of young children HBV infection leads to chronic *** is likely that a fully developed immune system contributes to HBV clearance(Dandri and Locarnini 2012;Bertoletti and Kennedy 2015).

关键词： infection mortality acute

SURFACE MODIFICATION OF POLYPROPYLENE MICROPOROUS MEMBRANE BY TETHERING POLYPEPTIDES

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Chinese Journal of Polymer Science 2006年第5期24卷 529-538页

作者：徐志康 Mathias Ulbricht Institute of Polymer Science Department of Polymer Science & Engineering Zhejiang University Hangzhou 310027 China Institut für Technische Chemie Universit t Duisburg-Essen45117 EssenGermany

Two kinds of polypeptides were tethered onto the surface of polypropylene microporous membrane （PPMM） through a ring opening polymerization of L-glutamate N-carboxyanhydride initiated by amino groups which were introduced by ammonia plasma and y-aminopropyl triethanoxysilane treatments. X-ray photoelectron spectroscopy （XPS）, attenuated total reflectance Fourier transform infrared spectroscopy （FT-IR/ATR）, scanning electron microscopy （SEM）, together with water contact angle measurements were used to characterize the modified membranes. XPS analyses and FT-IR/ATR spectra demonstrated that polypeptides are actually grafted onto the membrane surface. The wettability of the membrane surface increases at first and then decreases with the increase in grafting degrees of polypeptide. Platelet adhesion and murine macrophage attachment experiments reveal an enhanced hemocompatibility for the polypeptide modified PPMMs. All these results give evidence that polypeptide grafting can simultaneously improve the hemocompatibility as well as reserve the hydrophobicity for the membrane, which will provide a potential approach to improve the performance of polypropylene hollow fiber microporous membrane used in artificial oxygenator.

关键词： Polypropylene microporous membrane Graft polymerization Polypeptide Surface modification Biocompatibility.

A Multipathogen Bile Sample-based PCR Assay Can Guide Empirical Antimicrobial Strategies in Cholestatic Liver Diseases

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Journal of Clinical and Translational Hepatology 2022年第5期10卷 788-795页

作者： Michael Jahn Mustafa KÖzçürümez Sebastian Dolff Hana Rohn Dominik Heider Alexander Dechêne Ali Canbay Peter M.Rath Antonios Katsounas Department of Nephrology University Hospital EssenUniversity of Duisburg-EssenEssenGermany Department of Medicine Universitätsklinikum Knappschaftskrankenhaus BochumRuhr-University BochumBochumGermany Department of Infectious Diseases University Hospital EssenUniversity of Duisburg-EssenEssenGermany Department of Mathematics and Computer Science University of MarburgMarburgGermany Department for Internal Medicine Nuremberg Hospital NorthParacelsus Private Medical University NurembergNurembergGermany Institute of Medical Microbiology University Hospital EssenUniversity of Duisburg-EssenEssenGermany

Background and objectives:Polymerase chain reaction(PCR)techniques provide rapid detection of *** pilot study evaluated the diagnostic utility and clinical impact of multiplex real-time PCR(mRT-PCR,SeptiFast)*** microbial culture(CMC)in bile samples of patients with chronic cholestatic liver diseases(cCLDs),endoscopic retrograde cholangio-pancreatography(ERCP),and peri-interventional-antimicrobial-prophylaxis(pAP).Methods:We prospectively collected bile samples from 26 patients for microbiological analysis by CMC and *** of the results of both methods was determined by Krippendorff's alpha(α)for inter-rater reliability and the Jaccard index of ***:mRT-PCR_(bile)and CMC_(bile)results were concordant for only Candida albicans(α=0.8406;Jaccard index=0.8181).mRT-PCR_(bile)detected pathogens in 8/8 cases(100%),CMC_(bile)in 7/8(87.5%),and CMCblood in 5/8(62.5%)with clinical signs of ***_(bile),CMC_(bile),and CMCblood had identical detection results in 3/8(37.5%)with clinical signs of infection(two Klebsiella *** one Enterococcus faecium).The total pathogen count was significantly higher with mRT-PCR_(bile)than with CMC_(bile)(62 vs.31;χ^(2)=30.031,p<0.001).However,pathogens detected by mRT-PCR_(bile)were more often susceptible to pAP according to the patient infection/colonization history(PI/CH)and surveillance data for antibiotic resistance in our clinic(DARC).Pathogens identified by mRT-PC_(Rbile)and resistant to pAP by PI/CH and DARC were likely to be clinically ***:mRT-PCR in conjunction with CMCs for bile analysis increased diagnostic sensitivity and may benefit infection management in patients with cholestatic *** of mRT-PCR in a bile sample-based diagnostic routine can support more rapid and targeted use of antimicrobial agents in cCLD-patients undergoing ERCP and reduce the rate/length of unnecessary administration of broad-spectrum antibiotics.

关键词： ERCP PCR Antibiotic prophylaxis Cholestasis Cholangitis

Low-temperature catalytic methane deep oxidation over sol-gel derived mesoporous hausmannite (Mn_(3)O_(4)) spherical particles

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ChemPhysMater

ChemPhysMater 2024年第3期3卷 329-340页

作者： Patrick Ndouka Ndouka Stephane Kenmoe Jacques Richard Mache Elie Acayanka Dick Hartmann Douma Ralph Gebauer Patrick Mountapmbeme Kouotou Department of Chemistry Faculty of SciencesUniversity of MarouaP.O.Box 814 MarouaCameroon Department of Theoretical Chemistry University of Duisburg-EssenD-45141 EssenGermany Department of Mining Engineering School of Geology and Mining EngineeringUniversity of NgaoundéréP.O.Box 115 MeigangaCameroon Department of Inorganic Chemistry Faculty of ScienceUniversity of YaoundéIP.O.Box 812 YaoundéCameroon Groupe de Simulations Numériques en Magnétisme et Catalyse Facultédes Sciences et TechniquesUniversitéMarien NgouabiB.P.69 BrazzavilleCongo The Abdus Salam International Centre for Theoretical Physics(ICTP) 34151 TriesteItaly National Advanced School of Engineering of Maroua University of MarouaP.O.Box 46 MarouaCameroon Higher Institute of Agriculture WoodWater and EnvironmentUniversity of EbolowaP.O.Box 118 EbolowaCameroon

In this study,Mn_(3)O_(4) spherical particles(SPs)were synthesized by the sol-gel process,after which they were thermally annealed at 400℃,and comprehensively characterized.X-ray Diffraction(XRD)revealed that Mn_(3)O_(4) exhibited a tetragonal spinel structure,and Fourier transformed infrared(FTIR)spectroscopy identified surfaceadsorbed functional *** electron microscopy(SEM)and the specific surface area analyses by Brunauer−Emmett−Teller(BET)revealed a porous,homogeneous surface composed of strongly agglomerated spherical grains with an estimated average particle size of∼35 nm,which corresponded to a large specific surface area of∼81.5 m^(2)/g.X-ray photoelectron spectroscopy(XPS)analysis indicated that Mn_(3)O_(4) was composed of metallic cations(Mn^(4+),Mn_(3)+,and Mn^(2+))and oxygen species(O_(2)−,OH−and CO_(3)2−).The optical bandgap energy is∼2.55 *** of the catalytic performance of the Mn_(3)O_(4) SPs indicated T90 conversion of CH4 to CO_(2) and H2O at 398℃ for gas hourly space velocity(GHSV)of 72000 mL^(3) g^(−1) h^(−1).This observed performance can be attributed to the cooperative effects of the smallest spherical grain size with a mesoporous structure,which is responsible for the larger specific surface area and available surface-active oxygenated *** cooperative effect of the good reducibility,higher ratio of active species(OLat/OAds),and results of density functional theory(DFT)calculations suggested that the total oxidation of CH4 over the mesoporous Mn_(3)O_(4) SPs might take place via a two-term process in which both the Langmuir−Hinshelwood and Mars−van Krevelen mechanisms are cooperatively involved.

关键词： Sol-gel Manganese oxide Catalytic oxidation Methane Langmuir−Hinshelwood mechanism Mars−van Krevelen route Two−term process

High-dose biotin neither fosters remyelination nor stimulates malonyl coenzyme A synthesis in the regenerating nerve

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Neural Regeneration Research 2023年第7期18卷 1623-1624页

作者： Fabian Szepanowski Rebecca D.Steubing Cansu Güngör Jaqueline Zipfel Anne K.Mausberg Christoph Kleinschnitz Mark Stettner Department of Neurology and Center for Translational Neuro-and Behavioral Sciences(C-TNBS) University Medicine EssenUniversity Duisburg-EssenEssenGermany

Dear editor,Dysregulated inflammatory responses primarily account for damage to the central nervous system,however,neurodegenerative processes likely contribute to the pathophysiology of progressive forms of multiple sclerosis(MS).These pathophysiological aspects include axonal energy depletion and impaired remyelination capacity(Levin et al.,2014).The clinical efficacy of most disease-modifying therapies in MS to date has been achieved by targeting functions of the adaptive immune system(Cree et al.,2019;Szepanowski et al.,2021).

关键词： system synthesis neither

Calibrating SECCM measurements by means of a nanoelectrode *** intrinsic oxygen reduction activity of PtNi catalyst nanoparticles

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Nano Research 2022年第2期15卷 1564-1569页

作者： Emmanuel Batsa Tetteh Tobias Loffler Tsvetan Tarnev Thomas Quast Patrick Wilde Harshitha Barike Aiyappa Simon Schumacher Corina Andronescu Richard D.Tilley Xingxing Chen Wolfgang Schuhmann Analytical Chemistry-Center for Electrochemical Sciences Faculty of Chemistry and BiochemistryRuhr University BochumUniversitatsstr.150D-44780 BochumGermany Chemical Technology III Faculty of Chemistry and CENIDE-Center for NanointegrationUniversity Duisburg EssenCarl Benz Str.199D-47057 DuisburgGermany School of Chemistry and Australian Centre for NanoMedicine University of New South WalesSydney 2052Australia Research Group of Functional Materials for El

Scanning electrochemical cell microscopy(SECCM)is increasingly applied to determine the intrinsic catalytic activity of single electrocatalyst *** is especially feasible if the catalyst nanoparticles are large enough that they can be found and counted in post-SECCM scanning electron microscopy ***,this becomes impossible for very small nanoparticles and hence,a catalytic current measured in one landing zone of the SECCM droplet cannot be correlated to the exact number of catalyst *** show,that by introducing a ruler method employing a carbon nanoelectrode decorated with a countable number of the same catalyst particles from which the catalytic activity can be determined,the activity determined using SECCM from many spots can be converted in the intrinsic catalytic activity of a certain number of catalyst nanoparticles.

关键词： intrinsic electrocatalytic activity nanoelectrochemistry scanning electrochemical cell microscopy(SECCM) PtNi nanoparticles single entity electrochemistry alkaline medium

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采样数据系统的故障检测

自动化学报 2003年第2期29卷 306-311页

作者：张萍 DING Steven X 王桂增周东华清华大学自动化系北京100084 University of duisburg Duisburg

研究了采样数据系统的故障检测问题 .关键在于通过引入算子来分别描述连续时间的未知输入信号和故障信号对离散时间的残差信号的影响 ,从而把鲁棒性和灵敏度问题定义为一个优化问题 ,并给出了相应的解 .仿真例子验证了该方法的有效性 .

关键词：采样数据系统故障检测鲁棒性灵敏度故障诊断