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Maternal Group B Streptococcus Infection Correlates Inversely With Preeclampsia in Pregnant African American Women

Maternal-Fetal Medicine 2024年第1期6卷 23-28页

作者： Keun Soo Kwon Tzu Hsuan Cheng Simone A。Reynolds Jordan Zhou Huchong Cai Sharon Lee Ivan Velickovic Mudar Dalloul David Wlody Ming Zhang department of Anesthesiology State University of New York-Downstate Health Sciences UniversityNew York 11203USA department of Epidemiology and Biostatistics School of Public HealthState University of New York-Downstate Health Sciences UniversityNew York 11203USA department of Obstetrics and Gynecology State University of New York-Downstate Health Sciences UniversityNew York 11203USA

Objective:To determine whether an association exists between group B Streptococcus(GBS)colonization and preeclampsia among pregnant Black ***:This retrospective cross-sectional study involved Black women who gave birth at State University of New York Downstate Hospital between January 2010 and December *** were collected from the Obstetric department,including delivery date,time,mode of delivery,age of the mother,weeks of gestation at delivery,and antepartum *** GBS test results were originally determined using the eSwab transport *** was defined based on the American College of Obstetricians and Gynecologists criteria for the periods 2010–2012 and 2013–*** primary outcome was whether GBS was associated with the outcome of preeclampsia in the population of Black ***,including smoking status,gestational age,parity,body mass index,maternal age,and presence of herpes simplex virus(HSV)and human immunodeficiency virus(HIV)were examined as potential ***-squared test and logistic regression model were used,presenting odds ratios with 95%confidence intervals(P<0.050),analyzed with SAS on Demand for Academics(SAS Institute,Inc.,NY).Results:Among the 8,019 Black women included in this study,GBS-positive women(n=977)had a 53%reduction in the likelihood of being diagnosed with preeclampsia compared to GBS-negative women(adjusted odds ratio,0.47;95%confidence interval,0.32–0.70).We did not find evidence of differences in the distribution of smoking habits(P=0.783)or maternal age(P=0.107)between GBS-positive and GBS-negative ***,the GBS-positive women tended to be less likely to have a preterm delivery(9.62%(94/977)vs.24.24%(1707/7042),P<0.001),less likely to be nulliparous(33.37%(326/977)vs.37.87%(2667/7042),P=0.006),and less likely to be obese(51.38%(502/977)vs.55.30%(3894/7042),P<0.001)compared with GBS-negative *** contrast,GBS-positive women were more likely to have a comorbid infecti

关键词： Pregnancy outcome Preeclampsia GBS colonization African American Afro-Caribbean

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Association of spiritual well-being with quality of life among undergraduate nursing students

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Journal of Integrative Nursing 2024年第1期6卷 49-54页

作者： Ahmad SHAHID Hina HUSSAIN Nazia SHUAIB Ahmad RASOOL Fatima YOUNIS Zoya NASAB department of Nursing Professional College of Nursing and Health SciencesIslamabadPakistan department of Nursing Rawal Institute of Health SciencesIslamabadPakistan department of Nursing Rawal College of NursingIslamabadPakistan School of Nursing and health Zhengzhou UniversityZhengzhouChina

Objective:The study was conducted with the aim of determining the spiritual well-being(SWB)of nursing students and its association with quality of life(QOL).Materials and Methods:A cross-sectional analytical study was conducted with a sample size of 504 nursing students collected from January 2023 to March 2023 in the nursing institutes of Khyber Pakhtunkhwa,Pakistan,using convenient sampling techniques.A Spiritual health and Life-Orientation Measure(SHALOM)questionnaire for SWB and K-27 QOL(K-27 QOL)instrument were used for data collection that contains three ***:The number of female participants was in the majority(50.4%)compared to male nurses(49.6%).The overall mean score of SWB of the students was 3.79±0.48,while the mean K-27 QOL score was 3.73±*** were significant differences between the groups of gender(P=0.001),while no significant difference within the groups of semester(P=0.061)and college status(0.285).In QOL,there were significant differences within the groups of semester(P=0.000)and college status(P=0.036)while no significant difference in gender category(P=0.480).SHALOM score is positively and moderately correlated with QOL score(r=0.597,P<0.05).Conclusion:Spiritual practices are one of the important factors that are associated positively with QOL,therefore to enhance the QOL,it will require spiritual practices.

关键词： Nursing education nursing student quality of life spiritual nursing care spirituality well‑being

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health-oriented strategies are needed to optimize China’s 2025 clean air action plan

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Science Bulletin 2024年第13期69卷 2007-2008页

作者： Tao Xue Ning Kang Wei Wan Tong Zhu Institute of Reproductive and Child health/National health Commission Key Laboratory of Reproductive health and department of Epidemiology and Biostatistics/Ministry of Education Key Laboratory of Epidemiology of Major Diseases(PKU) School of Public HealthPeking University Health Science CentreBeijing 100191China State Environmental Protection Key Laboratory of Atmospheric Exposure and health Risk Management Center for Environment and HealthPeking UniversityBeijing 100871China Advanced Institute of Information Technology Peking UniversityHangzhou 311215China Clean Air Asia Beijing 100600China College of Environmental Sciences and Engineering Peking UniversityBeijing 100871China

Recently,China’s State Council issued the Continuous Improvement of Air Quality Action Plan(hereafter,the third action plan),which follows the Air Pollution Prevention and Control Action Plan(2013–2017)(hereafter,the first action plan)and the Three-Year Action Plan for Winning the Blue Sky Defense Battle(2018–2020)(hereafter the second action plan).The first two action plans yielded nationwide health benefits[1–3],from improving lung function[4]to saving medical expenditures[5].Based on our previous estimates[6],due to reductions in the fine particulate matter(PM2.5)level,implementation of the first and second action plans was expected to increase life expectancy by 2.11 and 3.68 months.

关键词： action hereafter nationwide

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Approach to loss of response to advanced therapies in inflammatory bowel disease

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World Journal of Gastroenterology 2024年第22期30卷 2902-2919页

作者： Nikil Vootukuru Abhinav Vasudevan department of Gastroenterology and Hepatology Eastern HealthVictoriaBox Hill 3128Australia Eastern health Clinical School Monash UniversityVictoriaBox Hill 3128Australia

BACKGROUND Remarkable progress over the last decade has equipped clinicians with many options in the treatment of inflammatory bowel *** now have the unique opportunity to provide individualized treatment that can achieve and sustain remission in many ***,issues of primary non-response(PNR)and secondary loss of response(SLOR)to non-tumour necrosis factor inhibitor(TNFi)therapies remains a common *** issues include the choice of optimization of therapy,identifying when dose optimization will recapture response,establishing optimal dose for escalation and when to switch *** To explores the issues of PNR and SLOR to non-TNFi *** This review explores the current evidence and literature to elucidate management options in cases of PNR/*** will also explore potential predictors for response following SLOR/PNR to therapies including the role of therapeutic drug monitoring(TDM).RESULTS In the setting of PNR and loss of response to alpha-beta7-integrin inhibitors and interleukin(IL)-12 and IL-23 inhibitors dose optimization is a reasonable option to capture *** Janus kinase inhibitors dose optimization can be utilized to recapture response with loss of *** The role of TDM in the setting of advanced non-TNFi therapies to identify patients who require dose optimization and as a predictor for clinical remission is not yet established and this remains an area that should be addressed in the future.

关键词： Inflammatory bowel disease Ulcerative colitis Crohn Biologics Interleukin-12 and interleukin-23 inhibitors Alpha-beta7-integrin inhibitors Janus kinase inhibitors Sphingosine-1-phosphate receptor modulators

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Study on vibration reduction of two-scale system coupled with dynamic vibration absorber

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Applied Mathematics and Mechanics(English Edition) 2024年第8期45卷 1335-1352页

作者： Honglin WAN Xianghong LI Yongjun SHEN department of Mathematics and Physics Shijiazhuang Tiedao University State Key Laboratory of Mechanical Behavior and System safety of Traffic Engineering Structures Shijiazhuang Tiedao University School of Mechanical Engineering Shijiazhuang Tiedao University

The dynamic vibration absorber with inerter and grounded stiffness(IGDVA) is used to control a two-scale system subject to a weak periodic perturbation. The vibration suppression effect is remarkable. The amplitude of the main system coupled with absorber is significantly reduced, and the high frequency vibration completely ***, through the slow-fast analysis and stability theory, it is found that the stability of the autonomous system exerts a notable regulating effect on the vibration response of the non-autonomous system. After adding the dynamic vibrator absorber, the center in the autonomous system changes to an asymptotically stable focus, consequently suppressing the vibration in the non-autonomous system. Further research reveals that the parameters of the absorber affect the real parts of the eigenvalues of the autonomous system, thereby regulating the stability of the system. Transitioning from a qualitative standpoint to a quantitative approach, a comparison of the solutions before and after the introduction of the dynamic absorber reveals that, when the grounded stiffness ratio and the mass ratio of the dynamic absorber are not equal, the high-frequency part in the analytical solution disappears. As a result, this leads to a reduction in the amplitude of the trajectory,achieving a vibration reduction effect.

关键词： 34E13 dynamic vibration absorber inerter O323 O328 two-scale system vibration control

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Neural plasticity in Parkinson's disease: a neuroimaging perspective

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Neural Regeneration Research 2024年第6期19卷 1203-1205页

作者： Christina Andica Koji Kamagata department of Radiology Juntendo University Graduate School of Medicine Faculty of health Data Science Juntendo University

Parkinson’s disease(PD) is a progressive neurodegenerative disorder characterized primarily by classical motor signs of bradykinesia,rigidity,tremors,and postural instability usually manifesti ng unilate rally or at least *** disease involves a loss of dopaminergic neurons projecting from the substantia nigra pars compacta to the dorsal striatum,

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Pregnancy and the disease recurrence of patients previously treated for differentiated thyroid cancer:A systematic review and meta analysis

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Chinese Medical Journal 2024年第5期137卷 547-555页

作者： Rui Shan Xin Li Ming Tao Wucai Xiao Jing Chen Fang Mei Shibing Song Bangkai Sun Chunhui Yuan Zheng Liu department of Maternal and Child health School of Public HealthPeking UniversityBeijing 100191China department of General Surgery Peking University Third HospitalBeijing 100191China department of Pathology Peking University Third HospitalSchool of Basic Medical SciencesPeking University Health Science CenterBeijing 100191China Information Management and Big Data Center Peking University Third HospitalBeijing 100191China

Background:Differentiated thyroid cancer(DTC)is commonly diagnosed in women of child-bearing age,but whether pregnancy influences the prognosis of DTC remains *** study aimed to summarize existing evidence regarding the association of pregnancy with recurrence risk in patients previously treated for ***:We searched PubMed,Embase,Web of Science,Cochrane,and Scopus based on the prespecified protocol registered at PROSPERO(CRD42022367896).After study selection,two researchers independently extracted data from the included *** quantitative data synthesis,we used random-effects meta-analysis models to pool the proportion of recurrence(for pregnant women only)and odds ratio(OR;comparing the risk of recurrence between the pregnancy group and the nonpregnancy group),*** we conducted subgroup analyses to explore whether risk of recurrence differed by response to therapy status or duration of follow-up *** also assessed quality of the included ***:A total of ten studies were *** sample size ranged from 8 to 235,with participants’age at pregnancy or delivery ranging from 28 to 35 *** follow-up time varied from 0.1 to 36.0 *** pooled proportion of recurrence in all pregnant patients was 0.13(95%confidence intervals[CI]:0.06-0.25;I^(2):0.58).Among six included studies reporting response to therapy status before pregnancy,we observed a trend for increasingly higher risk of recurrence from excellent,indeterminate,and biochemically incomplete to structurally incomplete response to therapy(P trend0.05)or the OR of recurrence in studies with a comparison group(P>0.05).Two included studies t

关键词： Thyroid cancer Pregnancy Recurrence Women Systematic review Meta-analysis

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Soleus arthrogenic muscle inhibition following acute lateral ankle sprain correlates with symptoms and ankle disability but not with postural control

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Journal of Sport and health Science 2024年第4期13卷 559-568,F0003页

作者： Kyung-Min Kim Joo-Sung Kim Alan R.Needle department of Sport Science Sungkyunkwan UniversitySuwon-si 16419Republic of Korea department of health and Human Performance Texas State UniversitySan MarcosTX 78666USA department of Public health&Exercise Science Appalachian State UniversityBooneNC 28608USA department of Rehabilitation Science Appalachian State UniversityBooneNC 28608USA

Background:Acute lateral ankle sprains(ALAS)are associated with long-term impairments and instability tied to altered neural *** muscle inhibition(AMI)has been observed in this population;however,relationships with injury-related impairments are unclear,potentially due to the resting,prone position in which AMI is typically *** AMI during bipedal stance may provide a better understanding of this ***:AMI was assessed in 38 young adults(19 ALAS within 72 h of injury:10 males,21.4±2.7 years;19 healthy controls:10 males,21.9±2.2 years;mean±SD)using the Hoffmann reflex(H-reflex)during bipedal *** stimulation was administered to identify the _(max)imal H-reflex(H_(max))and _(max)imal motor response(M_(max))from the soleus,fibularis longus,and tibialis anterior *** primary outcome measure was the H_(max)/M_(max) *** outcomes included acute symptoms(pain and swelling),postural control during bipedal stance,and self-reported ***:No significant group-by-limb interactions were observed for any ***,a significant group main effect was observed in the soleus muscle(F(1,35)=6.82,p=0.013),indicating significantly lower H_(max)/M_(max) ratios following ALAS(0.38±0.20)compared to healthy controls(0.53±0.16).Furthermore,lower H_(max)/M_(max) ratios in the soleus significantly correlated with acute symptoms and self-reported function but not with postural ***:This study supports previous evidence of AMI in patients with ALAS,providing insight into neurophysiologic impacts of musculoskeletal *** results suggest that assessing AMI in a standing position following acute injury may provide valuable insight into how AMI develops and guide potential therapeutic options to curb and offset the formation of joint instability.

关键词： Acute injuries Balance Hoffmann reflex Neural excitability Patient-reported outcomes

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Fundamentals and progress of the manifold method based on independent covers

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Science China(Technological Sciences) 2024年第4期67卷 966-991页

作者： SU HaiDong LIN ShaoZhong XIE ZhiQiang GONG YaQi QI YongFeng Material and Engineering Structure department Yangtze River Scientific Research InstituteWuhan 430010China Research Center of Water Engineering safety and Disaster Prevention of Ministry of Water Resources Wuhan 430010China

Aiming to solve mesh generation,computational stability,accuracy control,and other problems encountered with existing numerical methods,such as the finite element method and the finite volume method,a new numerical computational method for continuum mechanics,namely the manifold method based on independent covers(MMIC),is proposed based on the concept of mathematical manifolds,to form partitioned series solutions of partial differential *** partitions,the cover meshes have the characteristics of arbitrary shape,arbitrary connection,and arbitrary *** are expected to fundamentally solve the mesh generation problem and can also simulate the precise geometric boundaries of the CAD model and strictly impose boundary *** the selection of series solutions,local analytical solutions(such as series solutions at crack tips and series solutions in infinite domains)or proper forms of complete series can be used to reflect the local or global characteristics of the physical field to accelerate *** applications are presented.A new method of beam,plate,and shell analysis is *** deformation characteristics of beams,plates,and shells are simulated with polynomial series of suitable forms,and the analysis of curved beams and shells with accurate geometric representation is *** the static elastic analysis of two-dimensional structures,a mesh splitting algorithm is proposed,and h-p version adaptive analysis is carried out with error ***,automatic computation integrated with CAD is *** analysis is also attempted for the solution of differential equations of *** the one-dimensional convection-diffusion equation and Burgers equation,calculation results with high precision are obtained in strong convection and shock wave simulations,avoiding nonphysical *** solving the two-dimensional incompressible Navier-Stokes equation is also *** series solution formula is used to o

关键词： series solutions mesh generation adaptive analysis fixed meshes numerical manifold method

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One-Step to Prepare Lignin Based Fluorescent Nanoparticles with Excellent Radical Scavenging Activity

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Journal of Renewable Materials 2024年第5期12卷 895-908页

作者： Xujing Zhang Hatem Abushammala Debora Puglia Binbao Lu Pengwu Xu Weijun Yang Piming Ma The Key Laboratory of Synthetic and Biological Colloids Ministry of EducationSchool of Chemical and Material EngineeringJiangnan UniversityWuxi214122China Environmental health and safety Program College of Health SciencesAbu Dhabi UniversityP.O.Box 59911Abu DhabiUnited Arab Emirates Civil and Environmental Engineering department Materials Engineering CenterPerugia UniversityUdR INSTMTerni05100Italy

Fluorescent nanomaterials have attracted much attention,due to their unique luminescent properties and promis-ing applications in biomedical *** this study,lignin basedﬂuorescent nanoparticles(LFNP)with high yield(up to 32.4%)were prepared from lignin nanoparticles(LNP)by one-pot hydrothermal method with ethylene-diamine(EDA)and citric *** and chemical structure of LFNP were investigated by SEM,FT-IR,and zeta potential,and it was found that the structure of LFNP changed with the increase of citric acid *** showed the highestﬂuorescence intensity under UV excitation at wavelengths of 375–385 nm,with emis-sion wavelengths between 454–465 nm,and exhibited strong photoluminescence ***,with the increase of citric acid content,the energy gap(ΔE)gradually decreased from 3.87 to 3.14 eV,which corresponds to the gradual enhancement ofﬂuorescence *** also exhibited excellent antioxidant activity,with DPPH free radical scavenging rate increased from 80.8%for LNP up to 96.7%for LFNP,conﬁrming the great potential of these materials for application in biomedicine and cosmetic health care.

关键词： Lignin ﬂuorescent nanoparticles bioactivity photoluminescence mechanism

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