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华东地区睡眠医学新进展高级研修班

作者： Edward J.Morgan hawaii school of sleep medicine and technology september 2002

＜正＞Evidence-Based medicine Residents are not correct unless there is evidence Attendings are not correct unless there is evidence Professors are not correct unless there iS evidence

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Neuroimaging perspective in targeted treatment for type 2 diabetes melitus and sleep disorders

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Intelligent medicine 2022年第4期2卷 209-220页

作者： Karen M.von Deneen Malgorzata A.Garstka Center for Brain Imaging School of Life Science and TechnologyXidian UniversityXi’anShaanxi 710126China International Joint Research Center for Advanced Medical Imaging and Intelligent Diagnosis and Treatment&Xi’an Key Laboratory of Intelligent Sensing and Regulation of trans-Scale Life Information School of Life Science and TechnologyXidian UniversityXi’anShaanxi 710126China Core Research Laboratory Department of Endocrinologythe Second Affiliated Hospital of Xi’an Jiaotong UniversityXi’anShaanxi 710004China Department of Tumor and Immunology Precision Medical InstituteWestern China Science and Technology Innovation PortSchool of Medicinethe Second Affiliated Hospital of Xi’an Jiaotong UniversityXi’anShaanxi 710004China

Type 2 diabetes mellitus(T2DM)and sleep disorders(SD)have become important and costly health issues world-wide,particularly in *** are common diseases related to brain functional and structural abnormalities involving the hypothalamic-pituitary-adrenal(HPA)*** brains of individuals who suffer from both diseases simultaneously might be different compared to healthy *** review assessed current neuroimaging findings to develop alternative targeted treatments for T2DM and *** articles published between Jan-uary 2002 and september 2021 were searched in PubMed and Web of Science *** treatment methods for T2DM include dietary/weight-loss management,metformin or a combination of two non-insulin drugs,and melatonin for SD,though alternative therapies including electroacupuncture(EA)have been utilized in treating both of these diseases separately because they are convenient,affordable,and *** and al-ternative treatments for T2DM were somehow effective in treating *** studies of these disorders can achieve higher treatment efficacy by targeting brain areas,such as the hypothalamus(HYP),as visualized via diffusion tensor imaging(DTI),and functional magnetic resonance imaging(fMRI).DTI and fMRI can map the human brain and are utilized in many ***,we propose that neuroimaging studies could be used in treatment of SD in T2DM.

关键词： Neuroimaging Diabetes mellitus sleep disorders Alternative medicine Electroacupuncture Hypothalamic-pituitary-adrenal axis

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