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Periodic Layered Structure Formed during Interfacial Reaction

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Journal of Iron and Steel Research International 2016年第11期23卷 1127-1133页

作者： Xian-man ZHANG Hong-feng LUO Liu-yong SHI institute of Electrical and Mechanical Engineering Hainan University

A review of the periodic layered structure （PLS） formed during reactive diffusion was presented. The formation of PLS is a very interesting and complex phenomenon during the reactive diffusion process. It was firstly discovered occasionally. The formation of PLS has been reported in various solid state diffusion couples such as Zn/ Ni3 Si, Mg/SiO2, Zn/Cux Tiy and so on, and some controversial theoretical models and formation mechanism of PLS were put forward. However, there have been few reports about the PLS formed during hot dip. The development of PLS was reviewed, and the recent progress referring to the formation of PLS during the hot dip aluminizing of a no- vel Fe-Cr-B cast steel was especially introduced. However, not all of the borides could form PLS in their interracial reaction with molten Al. PLS only formed at the Cr-rich Fe2B/Al interface, while Mo-rich Fe2B fractured. A general qualitative description for the interracial reaction of Fe-Cr-B cast steel with molten Al was represented. Further inves- tigation on the constituents of the alternating phases and formation mechanism of PLS needs to be done. At last, the development trends of PLS were proposed.

关键词： periodic layered structure interfacial reaction reactive diffusion formation mechanism Fe-Cr-B cast steel

Storage time affects the level and diagnostic efficacy of plasma biomarkers for neurodegenerative diseases

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Neural Regeneration Research 2025年第8期20卷 2373-2381页

作者： Lifang Zhao Mingkai Zhang Qimeng Li Xuemin Wang Jie Lu Ying Han Yanning Cai Department of Clinical Biobank Xuanwu HospitalCapital Medical UniversityBeijingChina Beijing Geriatric Medical Research Center BeijingChina Department of Neurology Xuanwu HospitalCapital Medical UniversityBeijingChina Department of Radiology and Nuclear Medicine Xuanwu HospitalCapital Medical UniversityBeijingChina Beijing Key Laboratory of Magnetic Resonance Imaging and Brain Informatics BeijingChina Key Laboratory of Neurodegenerative diseases Ministry of EducationBeijingChina School of Biomedical Engineering Hainan UniversityHaikouHainan ProvinceChina Center of Alzheimer’s Disease Beijing Institute for Brain DisordersBeijingChina National Clinical Research Center for Geriatric Diseases BeijingChina institute of Biomedical Engineering Shenzhen Bay LaboratoryGaoke Innovation CenterShenzhenGuangdong ProvinceChina Department of Neurobiology Xuanwu HospitalCapital Medical UniversityBeijingChina

Several promising plasma biomarker proteins,such as amyloid-β(Aβ),tau,neurofilament light chain,and glial fibrillary acidic protein,are widely used for the diagnosis of neurodegenerative ***,little is known about the long-term stability of these biomarker proteins in plasma samples stored at-80°*** aimed to explore how storage time would affect the diagnostic accuracy of these biomarkers using a large *** samples from 229 cognitively unimpaired individuals,encompassing healthy controls and those experiencing subjective cognitive decline,as well as 99 patients with cognitive impairment,comprising those with mild cognitive impairment and dementia,were acquired from the Sino Longitudinal Study on Cognitive Decline *** samples were stored at-80°C for up to 6 years before being used in this *** results showed that plasma levels of Aβ42,Aβ40,neurofilament light chain,and glial fibrillary acidic protein were not significantly correlated with sample storage ***,the level of total tau showed a negative correlation with sample storage ***,in individuals without cognitive impairment,plasma levels of total protein and tau phosphorylated protein threonine 181(p-tau181)also showed a negative correlation with sample storage *** was not observed in individuals with cognitive ***,we speculate that the diagnostic accuracy of plasma p-tau181 and the p-tau181 to total tau ratio may be influenced by sample storage ***,caution is advised when using these plasma biomarkers for the identification of neurodegenerative diseases,such as Alzheimer's ***,in cohort studies,it is important to consider the impact of storage time on the overall results.

关键词： Alzheimer’s disease amyloid-β diagnostic ability glial fibrillary acidic protein neurodegeneration neurofilament light chain plasma biomarkers single molecule array storage time tau

EVALUATION OF TEMPERATURE RECORDS OBTAINED BY AWS IN hainan PROVINCE AND ADJUSTMENT OF CLIMATOLOGICAL TIME SERIES

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Journal of Tropical Meteorology 2008年第2期14卷 117-120页

作者：辛吉武许向春邢旭煌严经敏 hainan institute of Meteorological Science hainan Climate Center of Information Technology hainan meteorological information center

Based on the parallel air temperature data of automatic sounding and manual observations at 16 weather stations in hainan province from 2004 to 2005, a comparative analysis and evaluation is made for validity according to relevant standards. The results indicate that there are daily and seasonal differences between temperature observations recorded by automatic weather stations (AWSs) and with conventional methods. The reasons for the differences are the systematic error, the sensitivity of the two types of instruments to the environmental temperature change, the difference of the observation time and the effect of solar radiation. Because the long-range data were obtained from manual observation, an empirical conversion formula between the temperature records obtained by the instruments is provided for continuous use of the climate data after the changes in instruments.

关键词： automatic weather station temperature evaluation adjustment

OBSERVATION AND ANALYSIS OF SEA SURFACE WIND OVER THE QIONGZHOU STRAIT

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Journal of Tropical Meteorology 2010年第4期16卷 402-408页

作者：许向春辛吉武梁国锋邢绪煌陈有龙谢寒生 hainan institute of Meteorological Science Yangjiang Meteorological Bureau Guangdong Province hainan Climate Center hainan Meteorological Observatory hainan Meteorological Information Center

The spatial variation and diurnal fluctuation of sea surface wind over the Qiongzhou Strait were described using verified datasets from automatic weather stations on board a ferry, buoys, and on the coast. Results are as follows：（1） On average, sea surface wind speed is 34 m/s larger over the Qiongzhou Strait than in the coastal area. Sea surface wind speeds of 8.0 rrds or above （on Beaufort scale five） in the coastal area are associated with speeds 5-6 m/s greater over the surface of the Qiongzhou Strait. （2） Gust coefficients for the Qiongzhou Strait decrease along with increasing wind speeds. When coastal wind speed is less than scale five, the average gust coefficient over the sea surface is between 1.4 and 1.5; when wind speed is equal to scale five or above, the average gust coefficient is about 1.35. （3） In autumn and winter, the diurnal differences of average wind speed and wind consistency over the strait are less than those in the coastal area; when wind speed is 10.8 m/s （scale six） or above, the diurnal difference of average wind speed decreases while wind consistency increases for both the strait and the coast.

关键词： Qiongzhou Strait sea surface wind observational analysis statistical characteristics

The protective effect and underlying mechanism of hainan papaya water extract against neuronal apoptosis induced by A β 40

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Asian Pacific Journal of Tropical Medicine 2016年第7期9卷 653-658页

作者： Jiu-Hong Zhao Hai-Ying Zhang Xian-Fang Zhang Xu Dong Qi-Bing Liu Yue-Li Liu Yi-Di Huang Quan-Peng Zhang Gang Luo Zhi-Jian Ma Xi-Nan Yi Department of Anatomy Hainan Medical College Neuroscience Research institute Hainan Medical College School of Pharmacy Hainan Medical College

Objective:To investigate whether hainan papayas has protective effects in an Aimary neuron injury model and elucidate the underlying molecular mecha β 40-induced ***:Cultured primary neurons from the dorsal root ganglia(DRG) of Sprague-Dawley(SD) rats were treated with 20 μM A culture medium β 40 peptide,100 μg/L hainan papaya water extract,peptide plus extract,or for 24 *** viability was measured by MTT assay,and neuronal apoptosis was evaluated by DAPI *** signaling pathway-associated molecule activation and changes in Bax expression were analyzed by Western blotting and ***:A cell viability rate of(44.11±6.59)% in the Ading different concentrations of the extract β 40 group was rescued to(79.13±6.64)% by *** showed pyknotic nuclei in 39.5% of A β 40-treated cells;the fraction dropped to 17.4% in the 100 μg/L extract *** phosphorylation was observed in the Aent with 100 μg/L *** papaya water ex β 40 group but was ameliorated by pretreatmtract also prevented Ation of MEK,RSK1 and CREB associated with ERK signaling and d β 40-induced phosphorylaownregulated Bax expression in the ***:The resultss suggest that hainan papaya water extract has protective effects on neurons;the mechanism may be related to suppression of ERK signaling activation.

关键词： A β peptide Neuron protection ERK signaling pathway

Melatonin mitigates cold-induced damage to pepper seedlings by promoting redox homeostasis and regulating antioxidant profiling

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Horticultural Plant Journal 2024年第2期10卷 532-544页

作者： Muhammad Ahsan Altaf Yuanyuan Hao Huangying Shu Weiheng Jin Chuhao Chen Lin Li Yu Zhang Muhammad Ali Mumtaz Huizhen Fu Shanhan Cheng Guopeng Zhu Zhiwei Wang Key Laboratory for Quality Regulation of Tropical Horticultural Crops of hainan Province Sanya Nanfan Research InstituteHainan UniversitySanyaHainan 572025China Key Laboratory for Quality Regulation of Tropical Horticultural Crops of hainan Province School of HorticultureHainan UniversityHaikouHainan 570228China hainan Yazhou Bay Seed Laboratory SanyaHainan 572025China

This study assessed the influence of exogenous ME in the mitigation of cold damage in pepper seedlings. Melatonin(ME) is a dynamic molecule that helps plants cope with stress in several ways. Cold stress(CS) is one of the most important environmental factors that restrict plant growth and yield. Pepper(Capsicum annuum L.) is a valuable commercial crop, highly sensitive to CS. Thus, identifying an efficient strategy to mitigate cold damage is critical for long-term pepper production. For this purpose, the roots of pepper seedlings were pretreated with ME(5 μmol · L^(-1)) and exposed to CS for 7 d. The results indicated that CS suppressed pepper growth, hampered photosynthetic capacity, and damaged root architecture in pepper plants. In contrast, the production of reactive oxygen species(ROS), malondialdehyde(MDA), electrolyte leakage(EL), proline, and soluble sugars were enhanced in plants under CS. ME(5 μmol · L^(-1)) pretreatment reduced the negative effects of CS by recovering plant growth, root traits, gas exchange elements, and pigment molecules compared to CS control treatment. Furthermore, ME application efficiently reduced oxidative stress markers [hydrogen peroxide(H_(2)O_(2)), superoxide ion(O_(2)^(·-)), EL, and MDA] while increasing proline and soluble sugar content in pepper leaves. ME application combined with CS further increased antioxidant enzymes and related gene expression. Collectively, our results confirmed the mitigating potential of ME supplementation for CS by maintaining pepper seedling growth,improving the photosynthesis apparatus, regulating pigments, and osmolyte content.

关键词： Pepper Melatonin Cold stress Antioxidant enzyme Root trait

Multi-Trace Element and Rare Earth Element Composition of Coastal Casuarina Equisetifolia Ecosystem in hainan Island,China

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Journal of Rare Earths 2003年第S1期21卷 219-224页

作者：刘强毕华黄澜彭少麟 South China institute of Botany Chinese Academy of Sciences Geology Department Hainan Normal University Biology Department Hainan Normal University

46 trace elements including 14 rare earth elements (REEs) in coastal Casuarina equisetifolia plant-soil system from 9 sampling sites in hainan Island were detected by using ICP-MS. The aim is to explore the biogeochemical characteristics of migration and translocation of trace elements in soil-plant system and their function on the changes of environmental geochemistry. The results indicate that multi-trace elements in coastal sandy soil in hainan Island are at very low level. The multi-element patterns are quite similar among plant,sandy soil and upper continental crust (UCC),and the magnitudes of trace element concentrations among them are different in the general order of plant

关键词： trace elements Casuarina equisetifolia coastal ecosystem rare earths

srGAP3 promotes neurite outgrowth of dorsal root ganglion neurons by inactivating RAC1

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Asian Pacific Journal of Tropical Medicine 2014年第8期7卷 630-638页

作者： Quan-Peng Zhang Hai-Ying Zhang Xian-Fang Zhang Jiu-Hong Zhao Zhi-Jian Ma Dan Zhao Xi-Nan Yi Department of Anatomy Hainan Medical College Neuroscience Research institute Hainan Medical College

Objective:To explore effect of srGAP3 promotes neurite outgrowth of dorsal root ganglion ***:In this study,expression of Slit1 was observed predominantly in the *** expression of Robo2 and srCAP3 was detected in sensory neurons of postnatal rat cultured dorsal root ganglion(DRG).Furthermore,upregulation of srGAP3 following sciatic nerve transection was detected by immunohistochemistry and Western ***:It was observed that inhibition of nenrite outgrowth in cultured adult DRG neurons following treatment with anti-srGAP3 or anti-Robo2 was more effectively(1.5-fold higher) than that following treatment with an anti-BDNF positive control *** demonstrated that srGAP3 interacted with Robo2 and Slit1 protein to decrease Rac1-CTP activity in cultured adult rat DRG neurons and the opposite effect on Rac1-GTP activity was detected by co-immunoprecipitation and immunoblotting analyses following treatment with anti-Robo2 or *** data demonstrated a role for srGAP3 in nenrite outgrowth ol DRG sensory ***:Our observations suggest that srGAP3 promotes neurile outgrowth and filopodial growth cones by interacting with Robo2 to inactivate Rac1 in mammalian DRG neurons.

关键词： Rats Dorsal root ganglion Slit-Robo GTPase activating protein 3

Insight Into the Separation-of-Variable Methods for the Closed-Form Solutions of Free Vibration of Rectangular Thin Plates

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Computer Modeling in Engineering & Sciences 2025年第1期142卷 329-355页

作者： Yufeng Xing Ye Yuan Gen Li institute of Solid Mechanics Beihang University(BUAA)Beijing100191China

The separation-of-variable(SOV)methods,such as the improved SOV method,the variational SOV method,and the extended SOV method,have been proposed by the present authors and coworkers to obtain the closed-form analytical solutions for free vibration and eigenbuckling of rectangular plates and circular cylindrical *** taking the free vibration of rectangular thin plates as an example,this work presents the theoretical framework of the SOV methods in an instructive way,and the bisection–based solution procedures for a group of nonlinear eigenvalue ***,the explicit equations of nodal lines of the SOV methods are presented,and the relations of nodal line patterns and frequency orders are *** is concluded that the highly accurate SOV methods have the same accuracy for all frequencies,the mode shapes about repeated frequencies can also be precisely captured,and the SOV methods do not have the problem of missing roots as well.

关键词： Separation-of-variable method Rayleigh quotient nodal line eigenvalue equation bisection method