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Serious Burn by Sulfuric Acid: Case Report of Particular Therapeutic Strategy in a Non-Specialized ICU at Hôpital Principal de Dakar (hpd) Sénégal

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Open Journal of Emergency Medicine 2016年第3期4卷 62-68页

作者： M. M. Fall E. H. M. Niang C. D. Niang B. Niang A. K. Toure B. Diatta Department of Emergency Care and Anesthesiology H?pital Principal de Dakar (HPD) Dakar Sénégal Department of Orthopaedic Surgery and Traumatology H?pital Principal de Dakar (HPD) Dakar Sénégal Medical Service Chemical Industries of Senegal (ICS) Dakar Sénégal

Managing severe burns remains problematic due to the lack of specialized units, but also because of the delay in implementing emergency care. The aim is to show that an adapted strategy, can lead to satisfying management of chemical burns. The authors report retrospectively the case of a patient admitted for chemical burns, and treated in a non-specialized intensive care unit;a 38 years old male, referred for burns by sulfuric acid at his workplace. On admission to H15, the clinic did not reveal any vital organs failure. Burns were localized on two legs and soles of the two feet (18% TBSA). Treatment combined daily dressings with silver sulfadiazine. On day 14, the wound healing associated occlusive gauze dressing, iodine cream application, and mechanical debridement. On day 47, a 5% dermal autograft performed on right foot favored with good attachment grafts. On day 58, the patient was released after complete skin recovery. Then, in a non-specialized burn unit and without early surgery access, our wound healing adapted strategy was successful. In Senegal, chemical burns represent about 2.5% of burn cases. They are often from accidents on occupation job, while generally in Africa chemical burns result from criminal attacks. Patients with severe lesions are admitted in non-specialized environments after an extended time of transfer, and don’t have efficient initial care. This may explain the high morbidity and mortality after burns in our country. The lack of surgical facilities such as skin substitutes, in non-specialized unit on low or median income countries (LMICs), explains this long period of wound healing. The treatment of severe burn in LMICs is hazardous.

关键词： Chemical Burns Sulfuric Acid Adapted Strategy Senegal

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A COMPARATIVE STUDY OF CYTOTOXIC EFFECT OF VARIOUS HEMATOPORPHYRIN DERIVATIVES (hpd) BY LASER MICROIRRADIATION

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Chinese Science Bulletin 1987年第12期32卷 836-840页

作者：梁宏王兰岚陆仲康宋桂英邓燕华欧笑兰 Institute of Genetics Academia Sinica Beijing Institute of Genetics Academia Sinica Beijingince HPD in combination with light for treatment of malignancy was used by Dougherty et al. (1978) recent progress of photodynamic therapy using laser as light source to excite HPD both in diagnosis and therapy of cancer is currently receiving consid-

Since hpd in combination with light for treatment of malignancy was used by Dougherty et al. (1978), recent progress of photodynamic therapy using laser as light source to excite hpd both in diagnosis and therapy of c... 详细信息

关键词： LASER currently malignancy photodynamic killing earlier basically receiving manufactured visible

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FREE RADICALS GENERATED BY SPIN TRAPPING OF hpd-PHOTOSENTITIZATION

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Chinese Science Bulletin 1986年第1期31卷 57-61页

作者：张清刚黄宁娜蔡同茂刘芳吴正贵 Institute of Biophysics Academia Sinica Beijing Pharmaceutical Factory of Biochemicals Yangzhouematoporphyrin derivative (HPD) photosensitization therapy both for diagnosis and cure of solid neoplasms has been shown to be hopeful. So far some molecular mechanisms of HPD-photosensitization have been reported. A single oxygen (~1O_2) mechanism is generally thought to be predominar but contributions from a free radical

Hematoporphyrin derivative （hpd） photosensitization therapy both for diagnosis and cure of solid neoplasms has been shown to be hopeful. So far some molecular mechanisms of hpd-photosensitization have been reported.... 详细信息

关键词： neoplasms contributions derivative SPIN butane preparing substan illumination advice singlet

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From Myeloma to Plasma Cell Leukemia, Persistent Inequalities

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Open Journal of Blood Diseases 2023年第4期13卷 133-140页

作者： Mamadou Wague Gueye Nata Dieng Maguette Ndoye Mor Ngom Sokhna Moumi Mbacké Daffé Papa Silman Diawara Macoura Gadji Ndèye Marième Diagne Bécaye Fall Laboratory Federation H&#244pital Principal de Dakar (HPD) Dakar Senegal Onco-Hematology H&#244pital Principal de Dakar (HPD) Dakar Sénégal Biological and Oncological Hematology Department (BOHD) Centre National de Transfusion Sanguine (CNTS)/FMPOS-UCAD Dakar Sénégal

Multiple myeloma (MM) is both a complex and heterogeneous disease. Cytogenetic and molecular abnormalities lead to resistance to treatment and transformation to plasma cell leukemia, which is defined by the presence in circulating blood of plasma cells over 2 G/L, or more than 20% of leukocytes. It is an uncommon hematological malignancy with a poor prognosis. Against this backdrop, we report an observation of multiple myeloma transformed into plasma cell leukemia diagnosed at the Hôpital Principal de Dakar (hpd) that occurred on a 64-year-old man with a history of thyroidectomy followed for multiple myeloma presenting with Salmon et Durie stage IIIA and ISS stage I. Despite a marked improvement in management strategy, myeloma remains an almost invariably incurable disease. However, the development of genetic and molecular biomarkers is necessary to improve its prognosis.

关键词： Multiple Myeloma Plasma Cells Leukemia Personalized Medicine Risk Stratification

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Cardiovascular and Cerebrovascular Prognosis at 5 Years of Patients Who Presented with an Ischemic Stroke at Principal Hospital of Dakar

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World Journal of Cardiovascular Diseases 2022年第1期12卷 77-86页

作者： Waly Niang Mboup Mame Madjiguène Ka Serigne Cheikh Tidiane Ndao Demba Ware Balde Djibril Mari Ba Khadidiatou Dia Pape Diadji Fall Mouhamed Cherif Mboup Department of Cardiology Principal Hospital/Dakar (hpd) Dakar Senegal Department of Cardiology Military Hospital of Ouakam/Dakar (HMO) Dakar Senegal

Aims: To determine the cardiovascular and cerebrovascular prognosis at 5 years of patients who underwent an ischemic stroke in Senegal. Methods: We performed a descriptive, retrospective and exhaustive study conducted at Principal Hospital of Dakar. We included all patients hospitalized at Principal Hospital of Dakar from 2013 to 2019 for an ischemic stroke confirmed by a cerebral CT-Scanner or by magnetic resonance imaging, and who survived the acute phase. Results: Overall, one hundred and seventy-one (171) patients were gathered. Ninety-six (96) male patients account for 56.14% and seventy-five (75) female patients account for 43.86%, with a sex ratio of 1.28. Patients’mean age was 66.33 ±13.99 years. Twenty-one (21) young patients (12.35%), aged less than 50 years, presented with an ischemic stroke. Myocardial infarction was found in a female patient (0.6%) 3 months after she experienced an ischemic stroke, nine (9) patients (5.29%) underwent a recurrence of the ischemic stroke

关键词： Cardiovascular Cerebrovascular Prognosis Ischemic Stroke Dakar

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Macrophage Activation Syndrome in a Context of Pre-B Type Lymphoblastic Acute Leucemia: A Case Report

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Open Journal of Blood Diseases 2023年第4期13卷 141-147页

作者： Mamadou Wagué Gueye Sokhna Moumi Mbacké Daffé Mor Ngom Maguette Ndoye Papa Silman Diawara Nata Dieng Demba Makalou Macoura Gadji Macoura Gadji Awa Oumar Touré/Fall Bécaye Fall Laboratory Federation H&#244pital Principal de Dakar (HPD) Dakar Senegal Onco-Hematology H&#244pital Principal de Dakar (HPD) Dakar Senegal Laboratory CHR Saint-Louis Saint Louis Senegal Biological Hematology and Oncological Hematology Department (BOHD) Centre National de Transfusion Sanguine (CNTS)/FMPOS-UCAD Dakar Senegal Biology H&#244pital Aristide Le Dantec (HALD) Dakar Senegal

Macrophage activation syndrome (MAS) is linked to inappropriate stimulation of macrophage cells in the bone marrow and lymphoid system, resulting in abnormal phagocytosis of figurative blood elements and the release of pro-inflammatory cytokines. It is a rare and serious hyper-inflammatory condition of diagnostic and therapeutic emergency. MAS is characterized by non-specific clinical and laboratory signs associated with images of hemophagocytosis. MAS is either “primary” (familial or pediatric forms), or “secondary/reactive” to infection, neoplasia, or autoimmune disease. Hemopathies dominate MAS secondary to neoplasia. B-type acute lymphoblastic leukemia (ALL) is a hematological malignancy characterized by the proliferation and accumulation of B lymphoid progenitors, blocked at an early stage of differentiation, leading to suppression of polyclonal hematopoiesis and subsequent development of signs associated with bone marrow failure. In this context, we report the observation of a macrophage activation syndrome (MAS) associated with ALL, diagnosed at Hôpital Principal de Dakar/Senegal, in a 69-year-old patient with a well-controlled type 2 diabetes under oral antidiabetic therapy (OAD) and good general condition.

关键词： Macrophage Activation Syndrome Acute Lymphoblastic Leukemia Adult

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Atrial Fibrillation in Wolff Parkinson White Syndrome: About a Case in Senegal

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World Journal of Cardiovascular Diseases 2023年第1期13卷 1-6页

作者： Waly Niang Mboup Khadidiatou Dia Mame Madjiguène Ka Serigne Cheikh Tidiane Ndao Demba Ware Balde Djibril Mari Ba Mouhamed Cherif Mboup Adama Kane Department of Cardiology Principal Hospital of Dakar (HPD) Dakar Senegal Department of Cardiology Military Hospital of Ouakam (HMO) Dakar Senegal Department of Cardiology Aristide Le Dantec University Hospital Center Dakar Senegal

WOLFF PARKINSON and WHITE (WPW) syndrome is the most common form of pre-excitation. It is associated in some cases with atrial fibrillation with a high risk of sudden death. We report the case of a 64-year-old hypertensive woman with a history of ischemic stroke. She presented with hyperkinetic palpitations without hemodynamics instability on admission. The electrocardiogram recorded a complete tachyarrhythmia by pre-excitation atrial fibrillation, with a mean rate of 300 beats per minute. Electrophysiological investigation revealed an accessory pathway located at the ostium of the coronary sinus, which was successfully ablated by radiofrequency. A drug treatment based on flecaine 100 mg was introduced. The patient was asymptomatic after one month of outpatient follow-up.

关键词： Wolff Parkinson and White Atrial Fibrillation Senegal

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Etch Induction Time in CR-39 Detectors Etched in Na2CO3 Mixed NaOH Solution

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Chinese Physics Letters 2009年第9期26卷 105-107页

作者： N. Ali E. U. Khan K. Khan DPAM PLEAS P.O. Nilore Islamabad Pakistan P.D PINSTECH P.O. Nilore Islamabad Pakistan Department of Physics CIIT Islamabad Pakistan hpd PINSTECH P.O. Nilore Islamabad Pakistan

Six different solutions of 6M NaOH, containing different amounts of Na2CO3 at 70℃ were used for the revelation of latent damage trails in CR-39 plastic track detectors. These detectors were earlier exposed to fission fragments from ^252 Cf source for 30 min in vacuum and were then etched in the respective solutions for different etching time intervals of 5-20 min starting from 5min up to 160min. The etch induction time in each detector was obtained by extrapolating the intersection of resulting curves of track lengths and track diameters with the time axis.

关键词： No English Keyword

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钙型卤水不净化MVR制高纯盐案例分析

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中国井矿盐 2015年第2期46卷 1-4页

作者：冯金海夏洛特.贝瑟尔美国hpd公司

文章提供了一个在美国的钙型卤水生产氯化钠结晶系统案例,料液卤水来自一个即将作为天然气储存洞穴。主要工艺技术是利用一个单级hpd MVR制盐结晶器,未经卤水净化,生产纯度99.85%且粒径分布窄的盐。该系统设计独特,不需要卤水净化。取... 详细信息

文章提供了一个在美国的钙型卤水生产氯化钠结晶系统案例,料液卤水来自一个即将作为天然气储存洞穴。主要工艺技术是利用一个单级hpd MVR制盐结晶器,未经卤水净化,生产纯度99.85%且粒径分布窄的盐。该系统设计独特,不需要卤水净化。取消卤水净化环节可以降低系统的投资和运行成本。该系统不仅成本低,而且在线率高。

关键词： MVR 卤水净化钙型卤水制盐

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让脱硫废水实现零排放

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流程工业 2009年第10期 35-38页

作者： William A.Shaw hpd水务解决方案公司

在美国和欧盟地区，所有新建燃煤电厂都安装了涤气器，因为涤气器技术是被公认为最适合用于清除SO2的技术。而处理湿式涤气器废水的最好技术，就是一种零液体排放系统（ZLD）。由于未来很有可能会对发电厂用水施以更加严格的限制，能够... 详细信息

在美国和欧盟地区，所有新建燃煤电厂都安装了涤气器，因为涤气器技术是被公认为最适合用于清除SO2的技术。而处理湿式涤气器废水的最好技术，就是一种零液体排放系统（ZLD）。由于未来很有可能会对发电厂用水施以更加严格的限制，能够浓缩涤气器冲洗水流的零液体排放系统，必将像ZLD冷却塔排污系统一样成为常用配置。

关键词：脱硫废水零排放排放系统涤气器燃煤电厂电厂用水技术 SO2

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