检索结果-南通市图书馆

Ethnobotanical Study of Medicinal Plants Used for Treating Urinary Tract Infections in N’Djamena (Chad)

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

American Journal of Plant Sciences 2024年第1期15卷 46-55页

作者： Alhadj Djidda Mahamat Soudy Imar Djibrine Hamit Mht Alio Abakar Tadjadine Emmanuel Issa Issa Ramat Adam Abdel-Aziz Arada Baroua Abouna Elisabeth Ngo Bum laboratory of the Faculty of Human Health Sciences of the University of N’Djamena N’Djamena Chad Faculty of Sciences of the University of Maroua Maroua Cameroun Food Quality Control Centre (CECOQDA) N’Djamena Chad National Reference University Hospital of N’Djamena N’Djamena Chad Lute Sectorial Programme against aids and Hepatitis (PSLS) N’Djamena Chad Research and Livestock institute for Development (IRED) N’Djamena Chad

Introduction: Infection disease is a real publique health problem. The rise of resistance for modern antibiotic in infections treatment imposed us order alternatives. The study objective was to contribute in the knowledge of medicinal plants uses in urinary infections treatment in N’Djamena (Chad) in view for amelioration the traditional medicine in future. Methodology: The study was conducted in the city of N’Djamena in the Republic of Chad that interviewed 60 traditherapists on using 11 plants for urinary tract infections treatment. The methodology of this study consisted of the knowledge of medicinal plants that used by traditherapists, and the plants identification was done in the laboratory of IRED at Farcha. Results: A total of 60 traditherapists was interrogated on the plants used in the treatment of urinary tract infections among the population of N’Djamena. The majority of traditherapists interrogated in this study were male with the rate of 61.67% against female with the rate of 38.33%. The age range of traditherapists was between 20 to 80 years, 25 (41.67%) from the age range between 30 - 50 years and 35 (58.33%) in age range from 50 to 70 years. For the origin of their knowledge, the study showed that 72% of traditherapists inherited the knowledge from their family, while 15% inherited from the family and from training. The ethnic groups of the traditherapists were Sara (16%), Maraba (12%) and Massa (11%). According to the results, 18.33% were illiterates, 49% attended primary school and 33.34% the secondary school. Our study found that 11 species of plants belonging to 11 families were used in the treatment of urinary tract infection and the Ziziphus spina-christi was the most represented. According to traditherapists the Ziziphus spina-christi, Cassia obovata and Euphorbia hirta were the most frequent plants used in the urinary tract infections treatment. The parts of plants used in the treatment were leaves and bark, grained leaves and entire plants w

关键词： Urinary Infections Medicinal Plant and Traditherapists

Correlating phase transition with heat generation through calorimetric data

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

eScience 2024年第4期4卷 81-88页

作者： Kou Li Li Wang Yu Wang Xuning Feng Fachao Jiang Minggao Ouyang College of Engineering China Agricultural UniversityBeijing 100083China institute of Nuclear and New Energy Technology Tsinghua UniversityBeijing 100084China Beijing Key laboratory of Green Chemical Reaction Engineering and Technology Department of Chemical EngineeringTsinghua UniversityBeijing 100084China State Key laboratory of Intelligent Green Vehicle and Mobility Tsinghua UniversityBeijing 100084China

Despite the widespread utilization of Lithium-ion batteries(LIBs),concerns regarding safety during operation persist owing to accidents and potential risks of fires and *** comprehend the thermal dynamics that underlie severe LIB incidents,calorimetry tests have been prevalently employed for over three decades to examine the exothermic/endothermic behavior,reaction kinetics,and thermal interactions among LIB *** exists a substantial volume of calorimetry test results on various LIB electrodes,electrolytes,and other ***,this data showcases low consistency,yielding an unreliable database that obstructs a thorough understanding of LIB thermal *** this research,a comparative analysis of differential scanning calorimetry(DSC)results from materials utilized in the most commercialized LIB systems is *** analysis unveils notable discrepancies in DSC data amassed by different researchers,identifies five predominant causes of data inconsistency,proposes a standardized DSC operational procedure,and generates a set of self-consistent ***,an intrinsic safety spectrum is delineated and compared with X-ray diffraction(XRD)outcomes to elucidate the correlation between the crystal lattice structure and the thermal behavior of the *** work aids in the formation of a comparative DSC database,utilizing the vast but inconsistent literature ***,it clarifies the linkage between the material structure and thermal behavior,facilitating data-driven thermal analysis of LIBs.

关键词： Lithium-ion battery Differential scanning calorimetry Thermal behaviorData inconsistency Standardization operation procedure

Effects of organic acids on the leaching process of ion-adsorption type rare earth ore

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Rare Earths 2017年第12期35卷 1233-1238页

作者： Li Wang Chunfa Liao Youming Yang Haibo Xu Yanfei Xiao Chunhua Yan School of Metallurgy and Chemical Engineering Jiangxi University of Science and Technology Beijing National laboratory for Molecular Sciences State Key Laboratory of Rare Earth Materials Chemistry and Applications PKU-HKU Joint Laboratory in Rare Earth Materials and Bioinorganic Chemistry College of Chemistry and Molecular Engineering Peking University

To examine the activation of organic acids on the leaching process of ion-adsorption type rare earth ore（IRE-ore）, the leaching behavior of rare earth（RE） and zeta potential of IRE-ore were investigated in the absence and presence of carboxylic acids. The results show that all the tested organic acids（acetic acid,malonic acid, citric acid, tartaric acid, succinic acid, and malic acid） can promote RE extraction. At relatively high concentrations of organic acids, the activation efficiency of organic acids on RE extraction is generally consistent with their complexation ability; whereas at their low concentrations, the change of zeta potential on the IRE-ore surface with organic acid concentration and p H has a close association with RE extraction, which indicates that organic acids can impact the surface electrical property of IREore via their adsorption/desorption, and thereby increase/decrease the affinity of RE ions to *** the influence of organic acids on the IRE-ore surface electrical property also plays an important role in RE extraction in addition to their complexation with RE ions.

关键词： Ion-adsorption type rare earth ore Organic acid RE extraction Zeta potential Complexation

Dynamic and Temporal Transcriptomic Analysis Reveals Ferroptosis-Mediated Antileukemia Activity of S-DimethylarsinoGlutathione:Insights into Novel Therapeutic Strategy

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

CCS Chemistry 2022年第3期4卷 963-974页

作者： Xiaohan Xu Haibo Wang Hongyan Li Hongzhe Sun Department of Chemistry CAS-HKU Joint Laboratory of Metallomics on Health and EnvironmentThe University of Hong KongHong Kong 999077

S-dimethylarsino-glutathione(ZIO-101,darinaparsin®)exhibits broader antitumor activity and less toxicity than arsenic trioxide(ATO),a clinically used drug for acute promyelocytic leukemia(APL)***,the mechanisms of action underlying antileukemia activities of ZIO-101 remain largely ***,by integrating dynamic transcriptomic analysis and biochemical characterizations,we for the first time delineated that ZIO-101 exerted antiproliferative effects against leukemia cells via activating ferroptosis pathway,a newly discovered iron-dependent programmed cell death,at the early stage,as evidenced by abnormally elevated intracellular iron contents and lipid *** further demonstrated that silencing heme oxygenase 1(HMOX1),an important iron homeostasis-related gene,effectively attenuated ferroptosis induced by ZIO-101,with iron accumulation and lipid peroxidation being significantly ***,we discovered that ZIO-101 and kinase inhibitors(Dasatinib/Dactolisib)could synergistically kill leukemia cells,with a combination index of<1.0 under all the tested drug *** findings regarding the ferroptosis-mediated antileukemia activity of ZIO-101,based on the dynamic and temporal transcriptomic analysis,provide promising approaches to combat drug-resistant leukemia by combining ZIO-101 with kinase *** methodology may be further exploited for uncovering the modes of action of other drugs.

关键词： acute promyelocytic leukemia antileukemia arsenic darinaparsin® dynamic and temporal transcriptome ferroptosis mechanisms-driven development of new therapy

Prevalence and Factors Associated with Positivity of Antinuclear Antibodies (ANA) Patterns, Native Anti-DNA and Extractable Nuclear Antigens (ENA) Antibodies: Experience from a laboratory in Dakar

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Open Journal of Rheumatology and Autoimmune Diseases 2024年第1期14卷 26-36页

作者： Diop Abdou Diallo Thierno Abdoulaye Ndiaye Babacar Mahou Chantal Diop Marième Gaye Dubrous Phillippe Seck Abdoulaye Medical Biology laboratory Pasteur Institute of Dakar Dakar Senegal Cheikh Anta Diop University of Dakar Dakar Senegal

Background: Diagnosis of autoimmune diseases (AID) is challenging, due to overlapping features with other non-immune disorders. Anti-nuclear antibodies (ANA) are sensitive screening tests but anti-deoxyribonucleic acid-antibody (anti-DNA), and anti-extractable nuclear antigens (anti-ENA) are specific for aids. We aimed to look at ANA patterns in our patients and correlated them with anti-ENA for proper interpretation and better patient management cost-effectively. Methods: A retrospective study was conducted over 1 year from January to December 2022 who were tested for ANA at biology medical laboratory of Pasteur institute of Dakar. Anti-ENA and anti-DNA results were also analyzed for ANA-positive patients. Statistical analysis was performed using STATA 14.0, p Results: 216 patients were analyzed. Women predominated at 79.2% and mean age was 48 years [CI 95%, 46 - 50], with extremes of 10 and 89. Most represented age group was [41 - 60] with 38%. ANA was positive in 27 (12.5%) of patients, 59.2% of whom were strongly positive (titer of 1/1000, 1/3200 or 1/6400). The most common pattern was nuclear speckled, which was found in 77.8% of samples. Anti-ENA and anti-DNA positivity in ANA-positive patients was found respectively in 63% (17/27) and 1.4% (3/27) of the samples analyzed. Most commonly identified anti-ENA was anti-Sm 29.6%, anti-SSA 29.6%, anti-Ro-52 25.9%, anti-RNP 18.5% and anti-SSB 14.8% which was associated with speckled pattern. Association results indicated a significant relationship between both tests and between ANA titer in the anti-ENA- and ANA-positive patients (p 0.001). Conclusions: ANA, Anti-ENA and anti-DNA antibodies are essential for aids diagnosis. However, the testing repertoire should follow an algorithm comprising of clinical features, followed by ANA results with nuclear, mitotic, and cytoplasmic patterns, anti-ENA, and anti-DNA for a more meaningful, and cost-effective diagnostic approach.

关键词： Antinuclear Antibodies Extractable Nuclear antigen Autoimmune Disease Indirect Immunofluorescence

Composition-tuned oxidation levels of Pt-Re bimetallic nanoparticles for the etherification of allylic alcohols

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Nano Research 2018年第11期11卷 5902-5912页

作者： Yuhao Wang Lindong Li Ke Wu Rui Si Lingdong Sun Chunhua Yan Beijing National laboratory for Molecular Sciences State Key Laboratory of Rare Earth Materials Chemistry and Applications PKU-HKU Joint Laboratory in Rare Earth Materials and Bioinorganic Chemistry College of Chemistry and Molecular Engineering Peking University Beijing 100871 China Shanghai Synchrotron Radiation Facility Shanghai Institute of Applied Physics Chinese Academy of Sciences Shanghai 201204 China

The catalytic performance of metal nanoparticles is often affected by surface oxidation levels. Instead of post-synthesis oxidation/reduction, we propose an efficient method to modulate the oxidation levels by tuning the composition of bimetallic nanoparticles. Here we report a series of Pt–Re bimetallic nanoparticles synthesized via a facile thermal co-reduction process, with a uniform size of approximately 3 nm. The investigation of the growth of the Pt–Re nanoparticles suggests that the Re atoms were enriched on the surface, as confirmed by X-ray photoelectron spectroscopy. Furthermore, X-ray absorption spectroscopy showed that metallic Re was decreased and high-valency ReOx species were increased in particles with higher Re/Pt ratios. In the etherification of allylic alcohols catalyzed by Pt–Re nanoparticles of different compositions under ambient conditions, particles with higher Re/Pt ratios exhibited significantly better performances. The highest mass activity of Pt–Re bimetallic nanoparticles (127 μmol·g−1·s−1) was more than forty times that of the industrial catalyst CH3ReO3 (3 μmol·g−1·s−1). The catalytically active sites were associated with ReOx and could be tuned by adjusting the Pt ratio.

关键词： nanocatalysis Re Pt oxidation level composition allylic alcohol

Naturally occurring spike mutations influence the infectivity and immunogenicity of SARS-CoV-2

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Cellular & Molecular Immunology 2022年第11期19卷 1302-1310页

作者： Qiaoli Peng Runhong Zhou Na Liu Hui Wang Haoran Xu Meiqing Zhao Dawei Yang Ka-Kit Au Haode Huang Li Liu Zhiwei Chen aids institute Li Ka Shing Faculty of MedicineThe University of Hong KongHong Kong Special Administrative RegionPR China National Clinical Research Center for Infectious Diseases HKU AIDS Institute Shenzhen Research LaboratoryThe Third People’s Hospital of Shenzhen and The Second Affiliated Hospital of Southern University of Science and TechnologyShenzhenGuangdongPR China Department of Microbiology Li Ka Shing Faculty of MedicineThe University of Hong KongHong Kong Special Administrative RegionPR China Centre for Virology Vaccinology and Therapeutics LimitedThe University of Hong KongHong Kong Special Administrative RegionPR China hku aids institute joint laboratory Department of Clinical Microbiology and Infection ControlThe University of Hong Kong-Shenzhen HospitalShenzhenGuangdongPR China State Key laboratory of Emerging Infectious Disease The University of Hong KongHong Kong Special Administrative RegionPR China

Mutations in SARS-CoV-2 variants of concern(VOCs)have enhanced transmissibility and immune evasion with respect to current vaccines and neutralizing antibodies(NAbs).How naturally occurring spike mutations affect the infectivity and antigenicity of VOCs remains to be *** entry efficiency of individual spike mutations was determined in vitro using pseudotyped ***/c mice were immunized with 2-dose DNA vaccines encoding B.1.1.7,B.1.351,B.1.1.529 and their single *** and humoral immune responses were then compared to determine the impact of individual mutations on *** the B.1.1.7 lineage,Del69–70 and Del 144 in NTD,A570D and P681H in SD1 and S982A and D1118H in S2 significantly increased viral entry,whereas T716I resulted in a *** the B.1.351 lineage,L18F and Del 242–244 in the NTD,K417N in the RBD and A701V in S2 also increased viral entry.S982A weakened the generation of binding *** sera showed reduced cross-neutralization activity against B.1.351,B.1.617.2(Delta)and B.1.1.529(Omicron BA.1).S982A,L18F,and Del 242–244 hindered the induction of cross-NAbs,whereas Del 69–70,Del144,R246I,and K417N showed the opposite effects.B.1.351 elicited adequate broad cross-NAbs against both B.1.351 and *** immunogens tested,however,showed low neutralization against circulating *** addition,T-cell responses were unlikely affected by mutations tested in the *** conclude that individual spike mutations influence viral infectivity and vaccine *** VOC-targeted vaccines is likely necessary to overcome immune evasion from current vaccines and neutralizing antibodies.

关键词： SARS-CoV-2 Variants of Concern Single mutation neutralizing antibody T cell responses vaccine immunogenicity

Multi-twinned gold nanoparticles with tensile surface steps for efficient electrocatalytic CO_(2) reduction

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Science China Chemistry 2022年第11期65卷 2188-2196页

作者： Li-Wei Chen Yu-Chen Hao Jiani Li Linyu Hu Yu Guo Shuai Li Di Liu Zhejiaji Zhu Si-Qian Wu Hui-Zi Huang An-Xiang Yin Bo Wang Ya-Wen Zhang Ministry of Education Key laboratory of Cluster Science Beijing Key Laboratory of Photoelectronic/Electrophotonic Conversion MaterialsAdvanced Technology Research Institute(Jinan)School of Chemistry and Chemical EngineeringBeijing Institute of TechnologyBeijing 100081China Beijing National laboratory for Molecular Sciences State Key Laboratory of Rare Earth Materials Chemistry and ApplicationsPKU-HKU Joint Laboratory in Rare Earth Materials and Bioinorganic ChemistryCollege of Chemistry and Molecular EngineeringPeking UniversityBeijing 100871China

CO_(2) reduction reactions(CO_(2)RR) powered by renewable electricity can directly convert CO_(2) to hydrocarbons and fix the intermittent sustainable energy in portable chemical fuels. It is of great importance to develop advanced catalysts that can boost CO_(2)RR with high activity, selectivity, and efficiency at low overpotentials. Here, we report the solution synthesis using H_(2)O_(2) to modify the surface structures of gold multi-twinned nanoparticles(AuMPs) and create tensile surface steps. Calculations predicted significantly enhanced CO_(2) adsorption and boosted CO_(2)RR capabilities with inhibited hydrogen evolution reaction activity for the tensile surface steps with modified electronic structure. The H_(2)O_(2)-treated AuMPs with surface steps and 3.83% tensile lattices showed much higher activity and selectivity at lower overpotentials for CO_(2)RR than pristine gold *** CO-production current density reached about 98 mA cm^(-2) with a Faradaic efficiency of 95.7% at -0.30 V versus reversible hydrogen electrode in the flow cell, showing a half-cell energy efficiency as high as ~83%. Our strategy represents a rational catalyst design by engineering the surface structures of metal nanoparticles and may find more applicability in future electrocatalysis.

关键词： gold nanoparticles tensile lattice surface steps electrocatalysis CO_(2)reduction

Fabrication of gold nanoparticles with different morphologies in HEPES buffer

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Rare Metals 2010年第2期29卷 180-186页

作者： CHEN Rong WU Jiliang LI Hui CHENG Gang LU Zhong CHE Chi-Ming School of Chemical Engineering and Pharmacy Key Laboratory for Green Chemical Process(Ministry of Education) Hubei Key Lab of Novel Reactor and Green Chemical Technology Wuhan Institute of Technology Wuhan 430074 China Department of Chemistry and the hku-CAS joint laboratory on New Materials The University of Hong Kong Pokfulam Road Hong Kong China

Gold nanoparticles with different morphologies, such as spindle, octahedron, and decahedron were obtained by using different molar ratios of HAuCl4/HEPES in the presence and absence of surfactants at room *** nanoparticles were characterized by X-ray diffraction（XRD）, transmission electron microscopy（TEM）, high-resolution transmission electron microscopy（HRTEM）, scanning electron microcopy（SEM）, energy-dispersive X-rays analysis（EDX）, and selected area electron diffraction（SAED）.The kinetics of the formation of gold nanoparticles in HEPES buffer was studied by UV-visible *** formation of gold nanoparticles was strongly dependent on the concentration of HEPES and pH *** surfactants play a crucial role in the size and shape controlled synthesis of gold nanoparticles.

关键词： inorganic chemistry gold nanoparticle HEPES buffer surfactant