检索结果-南通市图书馆

Sulforaphane Attenuates CD36-mediated Platelet Hyperreactivity through Modulating cAMP/PKA/NOX2 Signaling in Hyperlipidemic Conditions

引用

Food Science and Human Wellness 2024年

作者： Weiqi Li Chunting Wu Xinyu Zhou Xinhui Huang Chunmei Zhang Yongjie Ma Jinqiu Hu Xiaoyan Bi Junyu Ma Mengyao Li Dong Lu Liang Hu Jiahua Fan Fuli Ya department of Nutrition School of Public Health Dali University department of Laboratory Teaching Center School of Public Health Dali University department of Health Management Gem Flower Xi'an Changqing Staff Hospital Shanghai Frontiers Science Center of tcm Chemical Biology Institute of Interdisciplinary Integrative Medicine Research Shanghai University of Traditional Chinese Medicine School of Integrative Medicine Shanghai University of Traditional Chinese Medicine School of Public Health Sun Yat-sen University Institute of Translational Medicine for Metabolic Diseases Dali University

Hyperlipidemia is a risk factor for clinically significant thrombotic events in cardiovascular diseases. Platelet reactivity in hyperlipidemic conditions is enhanced when platelet scavenger receptor CD36 recognizes oxidized lipids in oxidized low-density lipoprotein (ox-LDL) particles， a process that induces atherothrombosis. Sulforaphane (SFN) is a dietary isothiocyanate enriched in cruciferous vegetables and exerts multiple biological activities. The current study sought to investigate the efficacy of SFN on platelet hyperreactivity under hyperlipidemic conditions in vitro and in vivo. Using a series of platelet functional assays in human platelets in vitro， we demonstrated that SFN attenuated ox-LDL-increased platelet aggregation and activation (surface CD62P expression). Mechanistically， studies using pharmacological inhibitors clarified that these inhibitory effects of SFN were mainly modulated by down-regulating CD36-mediated activation of Src kinases， leading to enhanced activation of cAMP/PKA signaling， and resultant inhibition of NAD phosphate oxidase 2 (NOX2)-dependent generation of reactive oxygen species (ROS). Moreover， 12-week supplementation of SFN-enriched broccoli sprout extract (BSE， 0.06% diet) in hyperlipidemic C57BL/6J mice also decreased platelet hyperreactivity. Studies using pharmacological inhibitors of CD36， PKA and NOX2 showed that the efficacy of BSE supplementation was mainly through modulating CD36-mediated the cAMP/PKA/NOX2 signaling. Thus， through modulating the cAMP/PKA/NOX2 pathway and attenuating CD36-mediated platelet hyperreactivity， SFN may play important protective roles in atherothrombosis under hyperlipidemic conditions.

关键词：

来源：

同方期刊数据库评论

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Efficacy and Safety of Chinese Herbal Medicines Combined with Chemical Drugs for Alzheimer's Disease:A Systematic Review and Meta-Analysis

引用

World Journal of Traditional Chinese Medicine 2024年第1期10卷 1-13页

作者： Li Xu Wen-Jun Chen Cai-Jun Tian Yan Zhang Yan Ma Tian-Hao Li Hong-Jie Liu Zhe Zhang department of the First College English College of Foreign LanguageShandong University of Traditional Chinese MedicineJinanChina department of Oncology Linyi People's HospitalLinyiChina department of Internal Medicine of Traditional Chinese Medicine The First Clinical CollegeShandong University of Traditional Chinese MedicineJinanChina department of Chinese Materia Medica College of Traditional Chinese MedicineShandong University of Traditional Chinese MedicineJinanChina department of Medicinal Chemistry College of PharmacyShandong University of Traditional Chinese MedicineJinanChina Community Healthcare Center Shenzhen Traditional Chinese Medicine HospitalShenzhenChina department of Fundamentals of Traditional Chinese Medicine School of Traditional Chinese MedicineJinan UniversityGuangzhouChina Shandong Co-Innovation Center of Classic tcm Formula College of Traditional Chinese MedicineShandong University of Traditional Chinese MedicineJinanChina

Objective:To evaluate the efficacy and safety of Chinese herbal medicines(CHMs)combined with chemical drugs for the treatment of Alzheimer's disease(AD).Materials and Methods:Databases were searched to retrieve randomized controlled trials(RCTs)of CHMs combined with tacrine,galantamine,rivastigmine,donepezil,or memantine,following strict inclusion and exclusion *** research papers published in English,Chinese,and Japanese were *** primary outcome was the mini-mental state examination(MMSE)score and the secondary outcomes were AD assessment scale cognitive subscale(ADAS-Cog)score and safety ***-analysis was carried out using Rev Man 5.3 and subgroup analysis was conducted to identify the sources of ***:A total of 15 RCTs with 1386 participants were included in this *** donepezil was used in the retrieved ***-analyses showed that the combination of CHMs with donepezil led to significant improvement in the MMSE score(Z=9.45;P<0.00001;weighted mean difference[WMD]=2.68,95%confidence interval[CI]:2.12-3.24)and a significant decrease in the ADAS-Cog score(Z=5.53;P<0.00001;WMD=-3.79;95%CI:-5.13--2.44).Safety evaluation demonstrated that these combination treatments relieved adverse events such as insomnia(risk ratio[RR]=0.20,95%CI:0.06-0.68;P=0.01)and hive(RR=0.10;95%CI:0.01-0.73;P=0.02).Conclusions:The combination of CHMs with a chemical drug like donepezil led to significant improvements in patient cognition as well as a better safety profile when compared to the application of a chemical drug alone.

关键词： Alzheimer's disease Chinese herbal medicine donepezil memantine meta-analysis randomized controlled trials rivastigmine

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Global status and trends of metabolomics in diabetes: A literature visualization knowledge graph study

引用

World Journal of Diabetes 2024年第5期15卷 1021-1044页

作者： Hong Li Liu Li Qiu-Qing Huang Si-Yao Yang Jun-Ju Zou Fan Xiao Qin Xiang Xiu Liu Rong Yu College of Chinese Medicine Hunan University of Chinese MedicineChangsha 410208Hunan ProvinceChina College of International Education Hunan University of Chinese MedicineChangsha 410208Hunan ProvinceChina department of Science and Technology Hunan University of Chinese MedicineChangsha 410208Hunan ProvinceChina Hunan Key Laboratory of tcm Prescription and Syndromes Translational Medicine Hunan University of Chinese MedicineChangsha 410208Hunan ProvinceChina College of Graduate Hunan University of Chinese MedicineHunan ChangshaHunan ProvinceChina

BACKGROUND Diabetes is a metabolic disease characterized by hyperglycemia,which has increased the global medical burden and is also the main cause of death in most *** To understand the knowledge structure of global development status,research focus,and future trend of the relationship between diabetes and metabolomics in the past 20 *** The articles about the relationship between diabetes and metabolomics in the Web of Science Core Collection were retrieved from 2002 to October 23,2023,and the relevant information was analyzed using CiteSpace6.2.2R(CiteSpace),VOSviewer6.1.18(VOSviewer),and Bibliometrix software under R *** A total of 3123 publications were included from 2002 to *** the past two decades,the number of publications and citations in this field has continued to *** United States,China,Germany,the United Kingdom,and other relevant funds,institutions,and authors have significantly contributed to this *** Reports and PLoS One are the journals with the most publications and the most *** keyword co-occurrence and cluster analysis,the closely related keywords are"insulin resistance","risk","obesity","oxidative stress","metabolomics","metabolites"and"biomarkers".Keyword clustering included cardiovascular disease,gut microbiota,metabonomics,diabetic nephropathy,molecular docking,gestational diabetes mellitus,oxidative stress,and insulin *** detection analysis of keyword depicted that"Gene","microbiota","validation","kidney disease","antioxidant activity","untargeted metabolomics","management",and"accumulation"are knowledge frontiers in recent *** The relationship between metabolomics and diabetes is receiving extensive *** nephropathy,diabetic cardiovascular disease,and kidney disease are key diseases for future research in this *** microbiota,molecular docking,and untargeted metabolomics are key research directions in the *** a

关键词： Diabetes Metabolomics Bibliometric CiteSpace VOSviewer

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Guided bone regeneration in long-bone defect with a bilayer mineralized collagen membrane

引用

Collagen and Leather 2024年第1期5卷 85-100页

作者： Fuli Peng Xuelei Zhang Yilei Wang Rui Zhao Zhiwei Cao Siyu Chen Yunxuan Ruan Jingjing Wu Tianxi Song Zhiye Qiu Xiao Yang Yi Zeng Xiangdong Zhu Jian Pan Xingdong Zhang department of Orthopedics West China HospitalOrthopedic Research InstituteSichuan UniversityChengdu 610041SichuanChina National Engineering Research Center for Biomaterials Sichuan UniversityChengdu 610064SichuanChina Chengdu Integrated tcm and Western Medicine Hospital Chengdu First People's HospitalChengdu 610041SichuanChina department of Inspection School of MedicineJiangsu UniversityZhenjiang 212013China State Key Laboratory of Oral Diseases and National Center for Stomatology and National Clinical Research Center for Oral Diseases Department of Oral and Maxillofacial SurgeryWest China Hospital of StomatologySichuan UniversityChengdu 610041SichuanChina State Key Laboratory of New Ceramics and Fine Processing Key Laboratory of Advanced Materials of Min-istry of EducationSchool of Materials Science and EngineeringTsinghua UniversityBeijing 100084China

Bone regeneration for large,critical-sized bone defects remains a clinical challenge *** bone regeneration(GBR)is a promising technique for the repair of multiple bone defects,which is widely used in oral and maxillofacial bone defects but is still unsatisfied in the treatment of long bone ***,we successfully fabricated a bilayer mineralized collagen/collagen(MC/Col)-GBR membrane with excellent osteoinductive and barrier function by coating the MC particles prepared via in situ biomimetic mineralization process on one side of a sheet-like pure collagen *** aim of the present study was to investigate the physicochemical properties and biological functions of the MC/Col film,and to further evaluate its bone regeneration efficiency in large bone defect *** infrared spectra and X-ray diffraction patterns confirmed the presence of both hydroxyapatite and collagen phase in the MC/Col film,as well as the chemical interaction between *** microscope,scanning electron microscopy and atomic force microscope showed the uniform distribution of MC particles in the MC/Col film,resulting in a rougher surface compared to the pure Col *** quantitative analysis of surface contact angle,light transmittance and tensile strength demonstrated that the MC/Col film have better hydrophilicity,mechanical properties,light-barrier properties,*** vitro macrophage co-culture experiments showed that the MC/Col film can effectively inhibit macrophage proliferation and fusion,reducing fibrous capsule *** vivo bone repair assessment of a rabbit critical segmental radial defect proved that the MC/Col film performed better than other groups in promoting bone repair and regeneration due to their unique dual osteoinductive/barrier *** findings provided evidence that MC/Col film has a great clinical potential for effective bone defect repair.

关键词： Mineralized collagen Collagen Guided bone regeneration Artificial periosteum Bone defect repair

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

The chromosome-scale assembly of the Notopterygium incisum genome provides insight into the structural diversity of coumarins

引用

Acta Pharmaceutica Sinica B 2024年第8期14卷 3760-3773页

作者： Qien Li Yiqun Dai Xin-Cheng Huang Lanlan Sun Kaixuan Wang Xiao Guo Dingqiao Xu Digao Wan Latai An Zixuan Wang Huanying Tang Qi Qi Huihui Zeng Minjian Qin Jia-Yu Xue Yucheng Zhao Tibetan Medicine Research Center of Qinghai University Tibetan Medical CollegeQinghai UniversityXining 810016China School of Pharmacy Bengbu Medical UniversityBengbu 233030China department of Resources Science of Traditional Chinese Medicines School of Traditional Chinese PharmacyChina Pharmaceutical UniversityNanjing 210009China College of Horticulture Bioinformatics CenterAcademy for Advanced Interdisciplinary StudiesNanjing Agricultural UniversityNanjing 210095China Key Laboratory of Shaanxi Administration of Traditional Chinese Medicine for tcm Compatibility Shaanxi University of Chinese MedicineXi’an 712046China

Coumarins,derived from the phenylpropanoid pathway,represent one of the primary metabolites found in *** alignment of the tetrahydropyran(THP)and tetrahydrofuran(THF)rings with the lactone structure results in the formation of at least four types of complex ***,the mechanisms underlying the structural diversity of coumarin remain poorly ***,we report the chromosome-level genome assembly of Notopterygium incisum,spanning 1.64 Gb,with a contig N50 value of 22.7 Mb and 60,021 annotated protein-coding ***,we identified the key enzymes responsible for shaping the structural diversity of coumarins,including two p-coumaroyl CoA 2′-hydroxylases crucial for simple coumarins basic skeleton architecture,two UbiA prenyltransferases responsible for angular or linear coumarins biosynthesis,and five CYP736 cyclases involved in THP and THF ring ***,two bifunctional enzymes capable of catalyzing both demethylsuberosin and osthenol were identified for the first *** analysis implies that tandem and ectopic duplications of the CYP736 subfamily,specifically arising in the Apiaceae,contributed to the structural diversity of coumarins in ***,this study proposes a parallel evolution scenario for the complex coumarin biosynthetic pathway among different angiosperms and provides essential synthetic biology elements for the heterologous industrial production of coumarins.

关键词： Notopterygium incisum Parallel evolution Biosynthesis Pyranocoumarins Furanocoumarins

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

A comprehensive review of heart rate variability as an indicator in the regulation of the autonomic nervous system by acupuncture:a bibliometric analysis

引用

Integrative Medicine Discovery 2024年第14期8卷 1-14页

作者： Yi-Feng Shen Kun Zhu Jun-Long Zhu Xiao-Peng Huang De-Gui Chang Yao-Dong You Dong-Dong Yang tcm Regulating Metabolic Diseases Key Laboratory of Sichuan Province Hospital of Chengdu University of Traditional Chinese MedicineChengdu 610075China Clinical Medicine School Chengdu University of Traditional Chinese MedicineChengdu 610075China department of Neurology Hospital of Chengdu University of Traditional Chinese MedicineChengdu 610075China.

This study sought to conduct a bibliometric analysis of acupuncture studies focusing on heart rate variability(HRV)and to investigate the correlation between various acupoints and their effects on HRV by utilizing association rule mining and network analysis.A total of 536 publications on the topic of acupuncture studies based on *** disease keyword analysis revealed that HRV-related acupuncture studies were mainly related to pain,inflammation,emotional disorders,gastrointestinal function,and hypertension.A separate analysis was conducted on acupuncture prescriptions,and Neiguan(PC6)and Zusanli(ST36)were the most frequently used *** core acupoints for HRV regulation were identified as PC6,ST36,Shenmen(HT7),Hegu(LI4),Sanyinjiao(SP6),Jianshi(PC5),Taichong(LR3),Quchi(LI11),Guanyuan(CV4),Baihui(GV20),and Taixi(KI3).Additionally,the research encompassed 46 reports on acupuncture animal experiments conducted on HRV,with ST36 being the most frequently utilized *** research presented in this study offers valuable insights into the global research trend and hotspots in acupuncture-based HRV studies,as well as identifying frequently used combinations of *** findings may be helpful for further research in this field and provide valuable information about the potential use of acupuncture for improving HRV in both humans and animals.

关键词： heart rate variability acupuncture autonomous nerves system bibliometric analysis data mining

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Multi-omics Approach Reveals Influenza-A Virus Target Genes Associated Genomic,Clinical and Immunological Characteristics in Cancers

引用

Biomedical and Environmental Sciences 2024年第7期37卷 698-715页

作者： Jiaojiao Wang Yong Liao Pinglian Yang Weile Ye Yong Liu Chunxia Xiao Weixiong Liao Chunbo Chen Zhiping Liu Zunnan Huang Center of Scientific Research Department of CardiologyMaoming People’s HospitalMaoming 525000GuangdongChina department of Pharmacy Maoming People’s HospitalMaoming 525000GuangdongChina State Key Laboratory of Bioactive Molecules and Druggability Assessment Jinan UniversityGuangzhou 510632GuangdongChina Guangdong Province Key Laboratory of Pharmacodynamic Constituents of tcm and New Drugs Research College of PharmacyJinan UniversityGuangzhou 510632GuangdongChina Key Laboratory of Big Data Mining and Precision Drug Design of Guangdong Medical University Key Laboratory of Computer-Aided Drug Design of Dongguan CityKey Laboratory for Research and Development of Natural Drugs of Guangdong ProvinceSchool of PharmacyGuangdong Medical UniversityDongguan 523808GuangdongChina department of Critical Care Medicine Maoming People’s HospitalMaoming 525000GuangdongChina

Objective To examine the precise function of influenza A virus target genes(IATGs)in *** Using multi-omics data from the TCGA and TCPA datasets,33 tumor types were evaluated for *** expression in cancer cells was analyzed using transcriptome *** number variation(CNV)was assessed using GISTICS ***’s analysis was used to correlate mRNA expression with methylation *** was used for the enrichment ***’s correlation analysis was used to examine the association between IATG mRNA expression and *** ImmuCellAI algorithm was used to calculate the infiltration scores of 24 immune cell *** In 13 solid tumors,IATG mRNA levels were atypically *** for UCS,UVM,KICH,PCPG,THCA,CHOL,LAMI,and MESO,most cancers contained somatic IATG *** main types of CNVs in IATGs are heterozygous amplifications and *** most tumors,IATG mRNA expression is adversely associated with ***-PCR demonstrated that EGFR,ANXA5,CACNA1C,CD209,UVRAG were upregulated and CLEC4M was downregulated in KIRC cell lines,consistent with the TCGA and GTEx *** Genomic changes and clinical characteristics of IATGs were identified,which may offer fresh perspectives linking the influenza A virus to cancer.

关键词： Genomic changes Immune microenvironment Prognosis Drug resistance Experimental validation

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Activation of autophagy by Citri Reticulatae Semen extract ameliorates amyloid-beta-induced cell death and cognition deficits in Alzheimer’s disease

引用

Neural Regeneration Research 2024年第11期19卷 2467-2479页

作者： Yong Tang Jing Wei Xiao-Fang Wang Tao Long Xiaohong Xiang Liqun Qu Xingxia Wang Chonglin Yu Xingli Xiao Xueyuan Hu Jing Zeng Qin Xu Anguo Wu Jianming Wu Dalian Qin Xiaogang Zhou Betty Yuen-Kwan Law Dr.Neher’s Biophysics Laboratory for Innovative Drug Discovery State Key Laboratory of Quality Research in Chinese MedicineMacao University of Science and TechnologyMacao Special Administrative RegionChina Sichuan Key Medical Laboratory of New Drug Discovery and Druggability Evaluation Luzhou Key Laboratory of Activity Screening and Druggability Evaluation for Chinese Materia Medica Southwest Medical UniversityLuzhouSichuan ProvinceChina Eye School and Key Laboratory of Sichuan Province Ophthalmopathy Prevention&Cure and Visual Function Protection of Chengdu University of tcm ChengduSichuan ProvinceChina School of Basic Medical Sciences Southwest Medical UniversityLuzhouSichuan ProvinceChina department of Ophthalmology The Affiliated Hospital of Southwest Medical UniversityLuzhouSichuan ProvinceChina department of Neurology The First People’s Hospital of NeijiangNeijiangSichuan ProvinceChina

Amyloid-beta-induced neuronal cell death contributes to cognitive decline in Alzheimer’s *** Reticulatae Semen has diverse beneficial effects on neurodegenerative diseases,including Parkinson’s and Huntington’s diseases,however,the effect of Citri Reticulatae Semen on Alzheimer’s disease remains *** the current study,the anti-apoptotic and autophagic roles of Citri Reticulatae Semen extract on amyloid-beta-induced apoptosis in PC12 cells were first *** Reticulatae Semen extract protected PC12 cells from amyloid-beta-induced apoptosis by attenuating the Bax/Bcl-2 ratio via activation of *** addition,Citri Reticulatae Semen extract was confirmed to bind amyloid-beta as revealed by biolayer interferometry in vitro,and suppress amyloid-beta-induced pathology such as paralysis,in a transgenic Caenorhabditis elegans in vivo ***,genetically defective Caenorhabditis elegans further confirmed that the neuroprotective effect of Citri Reticulatae Semen extract was *** importantly,Citri Reticulatae Semen extract was confirmed to improve cognitive impairment,neuronal injury and amyloid-beta burden in 3×Tg Alzheimer’s disease *** revealed by both in vitro and in vivo models,these results suggest that Citri Reticulatae Semen extract is a potential natural therapeutic agent for Alzheimer’s disease via its neuroprotective autophagic effects.

关键词： Alzheimer’s disease amyloid-beta apoptosis autophagy Caenorhabditis elegans Citri Reticulatae Semen

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Goji berry-derived phenylpropionyl phenylethylamine derivatives protect against ethanol-induced hepatic damage

引用

Food Science and Human Wellness 2024年

作者： Zhengqun Zhou Zhaodi Che Jiancong Mai Rui Zhang Zhihui Luo Yifang Li Kwokfai So Jia Xiao Xinsheng Yao Hao Gao GMH Institute of CNS Regeneration Guangdong Medical Key Laboratory of Brain Function and Diseases Jinan University Clinical Medicine Research Institute and department of Metabolic and Bariatric Surgery the First Affiliated Hospital of Jinan University Institute of Traditional Chinese Medicine and Natural Products College of Pharmacy/Guangdong Province Key Laboratory of Pharmacodynamic Constituents of tcm and New Drugs Research/International Cooperative Laboratory of Traditional Chinese Medicine Modernization and Innovative Drug Development of Ministry of Education (MOE) of China Jinan University

Goji berry is a famous edible and medicinal substance around the world. In this research， 15 phenylpropionyl phenylethylamine derivatives (1-15)， including one new compound (1)， were separated and identified from goji berry. All isolates were elucidated via extensive NMR spectral analyses and chemical techniques. Six known isolates were first obtained from Lycium genus. Six isolates were effectively split into double chromatographic peaks accompanied by the basically identical areas， indicating they belong to racemates. The ORAC experiment indicated that all isolates displayed a capacity of scavenging free radicals， and most of them exhibited higher ORAC values than EGCG. In ethanol/palmitic acid (PA)-established in vitro hepatocyte injury model， four phenylpropionyl phenylethylamine derivatives (1， 2， 9， and 15) significantly alleviated hepatocyte injury， among which compound 1 exerted the strongest protective activity. Notably， the hepatoprotective effect of compound 1 was further confirmed in ethanol-established liver damage mouse model， reflected by the reduction of lipid accumulation and the attenuation of pathological alteration. Combined with the in vitro results， the in vivo observations suggested that compound 1 suppressed cell apoptosis and the outburst of inflammation. Our findings provided first-hand evidence proving that goji berry-derived phenylpropionyl phenylethylamine derivatives hold a potential in treating alcoholic liver disease.

关键词：

来源：

同方期刊数据库评论

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Efficacy of Qiancao(Radix Rubiae Cordifoliae) and Haipiaoxiao(Endoconcha Sepiellae), a traditional Chinese herb pair, on abnormal uterine bleeding in rats with incomplete abortion

引用

Journal of Traditional Chinese Medicine 2022年第5期42卷 758-763页

作者： ZHANG Tiantian LI Guowen CHU Zhifeng LI Jie YU Lijun GAO Yuan WANG Huifeng department of Pharmacy Shanghai Songjiang Fangta Hospital of TCMShanghai 201600China department of Pharmacy Shanghai TCM-Integrated HospitalShanghai 200080China department of Traditional Chinese Medicine Shanghai Songjiang Fangta Hospital of TCMShanghai 201600China

OBJECTIVE: To investigate the most effective weight ratio of Qiancao(Radix Rubiae Cordifoliae) and Haipiaoxiao(Endoconcha Sepiellae) used to produce decoction for the treatment of abnormal uterine bleeding(AUB) in rats with incomplete abortion, and to study the possible mechanism. METHODS: The models of AUB were established by incomplete drug abortion with mifepristone and misoprostol in pregnant rats. The therapeutic effects of decoctions made by eight different weight ratios of Qiancao(Radix Rubiae Cordifoliae) and Haipiaoxiao(Endoconcha Sepiellae) were observed. RESULTS: Statistical analysis revealed that the most effective weight ratio of Qiancao(Radix Rubiae Cordifoliae) and Haipiaoxiao(Endoconcha Sepiellae) to treat AUB in this study was 2∶1. CONCLUSION: The insights gained from this study would improve understanding of the mechanisms involved in the effect of Qiancao(Radix Rubiae Cordifoliae) and Haipiaoxiao(Endoconcha Sepiellae) on AUB.

关键词： uterine hemorrhage Qiancao(Radix Rubiae Cordifoliae) Haipiaoxiao(Endoconcha Sepiellae) herb pair weight ratio

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：