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The study on the bottom friction and the breaking coefficient for typhoon waves in radial sand ridges—the Lanshayang Channel as an example

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Acta Oceanologica Sinica 2015年第3期34卷 99-107页

作者： XU Zhuo ZHANG Wei LU Peidong CHEN Kefeng College of Harbor Coastal and Offshore Engineering Hohai University The development Office of Yangtze River in Tongzhou district River and Harbor Department Nanjing Hydraulic Research Institute

Owing to the interactions among the complex terrain, bottom materials, and the complicate hydrodynam-ics, typhoon waves show special characteristics as big waves appeared at the high water level （HWL） and small waves emerged at low and middle water levels （LWL and MWL） in radial sand ridges （RSR）. It is as-sumed that the mud damping, sandy bed friction and wave breaking effects have a great influence on the typhoon wave propagation in this area. Under the low wave energy, a mud layer will form and transport into the shallow area, thus the mud damping effects dominate at the LWL and the MWL. And high Collins coef-ficient （c around 1） can be applied to computing the damping effects at the LWL and the MWL. But under the high wave energy, the bottom sediment will be stirred and suspended, and then the damping effects disappear at the HWL. Thus the varying Collins coefficient with the water level method （VCWL） is imple-mented into the SWAN to model the typhoon wave process in the Lanshayang Channel （LSYC） of the RSR, the observed wave data under “Winnie” （“9711”） typhoon was used as validation. The results show that the typhoon wave in the RSR area is able to be simulated by the VCWL method concisely, and a constant wave breaking coefficient （γ） equaling 0.78 is better for the RSR where wide tidal flats and gentle bed slopes exist.

关键词： typhoon wave radial sand ridges RSR mud damping effects varying Collins coefficient with the water level method wave breaking coefficient

Insoluble carbonaceous materials as electron shuttles enhance the anaerobic/anoxic bioremediation of redox pollutants:Recent advances

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Chinese Chemical Letters 2022年第1期33卷 71-79页

作者： Ning Li Jin Jiang Yanbin Xu Hanping Pan Xiaonan Luo Yingbin Hu Jie Cao Key Laboratory for City Cluster Environmental Safety and Green development of the Ministry of Education Institute of Environmental and Ecological EngineeringGuangdong University of TechnologyGuangzhou 510006China Southern Marine Science and Engineering Guangdong Laboratory(guangzhou) Guangzhou 511458China School of Environmental Science and Engineering Guangdong University of TechnologyGuangzhou 510006China

Carbonaceous materials can accelerate extracellular electron transfer for the biotransformation of many recalcitrant,redox-sensitive contaminants and have received considerable attention in fields related to anaerobic *** important electron shuttles(ESs),carbonaceous materials effectively participate in redox biotransformation processes,especially microbially-driven Fe reduction or oxidation coupled with pollutions transformation and anaerobic fermentation for energy and by-product *** related bioprocesses are reviewed here to show that carbonaceous ESs can facilitate electron transfer between microbes and extracellular *** classification and characteristics of carbon-containing ESs are summarized,with an emphasis on activated carbon,graphene,carbon nanotubes and carbonbased immobilized *** influencing factors,including carbon material properties(redox potential,electron transfer capability and solubility)and environmental factors(temperature,p H,substrate concentration and microbial species),on pollution catalytic efficiency are ***,we briefly describe the prospects of carbonaceous ESs in the field of microbial-driven environmental remediation.

关键词： Carbonaceous materials Electron shuttle Redox mediator Extracellular electron transfer Anaerobic bioremediation

Total glucosides of Rhizoma Smilacis Glabrae:a therapeutic approach for psoriasis by regulating Th17/Treg balance

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Chinese Journal of Natural Medicines 2023年第8期21卷 589-598页

作者： TANG Yingzhan YU Jingyi ZHAO Wen LIU Juyan PENG Hongying ZHANG Haoran JIANG Zhenzhou YU Qinwei ZHANG Luyong New drug screening center Jiangsu Center for Pharmacodynamics Research and EvaluationChina Pharmaceutical UniversityNanjing 210009China guangzhou Baiyunshan Jingxiutang Pharmaceutical Co. Ltd.Guangzhou 510130China guangzhou Pharmaceutical Holdings Co. Ltd.Guangzhou 510103China Center for Drug Research and development Guangdong Pharmaceutical UniversityGuangzhou 510006China

Total glucosides of Rhizoma Smilacis Glabrae(RSG)are selective immunosuppressants that exhibit primary efficacy in the treatment of rheumatoid arthritis through targeted inhibition of activated T *** this study,we aimed to investigate the potential application of RSG in the treatment of psoriasis and elucidate its mechanism of action and material *** findings revealed significant improvements upon administration of RSG in an imiquimod(IMQ)-induced psoriasis *** improvements were characterized by a remarkable increase in the number of tail scales in mice and a substantial amelioration of skin erythema,ulceration,and *** transcriptome sequencing and T-cell flow sorting assay,we identified notable effects of RSG on the modulation of various cellular ***,RSG prominently down-regulated the Th17/Treg ratio in damaged skin tissues and reduced the proportion of G2 phase ***,RSG exhibited a stimulatory effect on the proliferation and differentiation of epithelial *** particular interest,we discovered thatβ-sitosterol,sitostenone,stigmasterol,smiglanin,and cinchonain Ib displayed potent inhibitory effects on the IL-17-mediated inflammatory response in HaCaT *** summary,our study highlights the therapeutic potential of RSG in the treatment of psoriasis,attributed to its ability to regulate the Th17/Treg *** findings contribute to the development of new indications for RSG and provide a solid theoretical foundation for further exploration in this field.

关键词： Psoriasis Rhizoma Smilacis Glabrae Th17/Treg balance Inflammation Epithelium development

Effect of the biosynthesis of the volatile compound phenylacetaldehyde on chloroplast modifications in tea (Camellia sinensis) plants

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Horticulture Research 2023年第3期10卷 98-109页

作者： Lanting Zeng Xiaochen Zhou Xiumin Fu Yilong Hu Dachuan Gu Xingliang Hou Fang Dong Ziyin Yang Guangdong Provincial Key Laboratory of Applied Botany&Key Laboratory of South China Agricultural Plant Molecular Analysis and Genetic Improvement South China Botanical GardenChinese Academy of SciencesNo.723 Xingke RoadTianhe DistrictGuangzhou 510650China South China National Botanical Garden No.723 Xingke RoadTianhe DistrictGuangzhou 510650China University of Chinese Academy of Sciences No.19A Yuquan RoadBeijing 100049China Guangdong Food and Drug Vocational College No.321 Longdongbei RoadTianhe DistrictGuangzhou 510520China

Plant volatile compounds have important physiological and ecological ***(PAld),a volatile phenylpropanoid/benzenoid,accumulates in the leaves of tea(Camellia sinensis)plants grown under continuous *** study was conducted to determine whether PAld production is correlated with light and to elucidate the physiological functions of PAld in tea ***,the upstream mechanism modulating PAld biosynthesis in tea plants under different light conditions as well as the effects of PAld on chloroplast/chlorophyll were *** biosynthesis of PAld was inhibited under light,whereas it was induced in *** structural gene encoding aromatic amino acid aminotransferase 1(CsAAAT1)was expressed at a high level in darkness,consistent with its importance for PAld ***,the results of a transcriptional activation assay and an electrophoretic mobility shift assay indicated CsAAAT1 expression was slightly activated by phytochrome-interacting factor 3-2(CsPIF3-2),which is a light-responsive transcription ***,PAld might promote the excitation of chlorophyll in dark-treated chloroplasts and mediate electron energy transfer in ***,the accumulated PAld can degrade chloroplasts and chlorophyll,with potentially detrimental effects on ***,PAld biosynthesis is inhibited in tea leaves by red and blue light,thereby decreasing the adverse effects of PAld on chloroplasts during *** conclusion,the regulated biosynthesis of PAld in tea plants under light and in darkness leads to chloroplast *** results of this study have expanded our understanding of the biosynthesis and functions of volatile phenylpropanoids/benzenoids in tea leaves.

关键词： volatile inhibited thereby

Applications of lignin-derived catalysts for green synthesis

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Green Energy & Environment 2019年第3期4卷 210-244页

作者： Yuting Zhu Zhijing Li Jinzhu Chen Key Laboratory of Renewable Energy Guangzhou Institute of Energy ConversionChinese Academy of SciencesNo.2 Nengyuan RoadWushanTianhe DistrictGuangzhou 510640GuangdongChina Guangdong Engineering and Technology Research Centre of Graphene-Based Materials and Products Department of ChemistryCollege of Chemistry and Materials ScienceJinan UniversityNo.601 Huangpu Avenue WestTianhe DistrictGuangzhou 510632GuangdongChina University of Chinese Academy of Sciences No.19 Yuquan RoadShijingshan DistrictBeijing 100049China Key Laboratory of Biomass Chemical Engineering of Ministry of Education Department of Chemical and Biological EngineeringZhejiang UniversityHangzhou 310027ZhejiangChina

This review intends to introduce the application of lignin-derived catalyst for green organic synthesis over latest two decades and aims to present a renewable alternative for conventional catalyst for future industry application. The structure of lignin is initially introduced in this review. Then, various pretreatment and activation technologies of lignin are systematically presented, which includes physical activation for the formation of well-developed porosity and chemical activation to introduce catalytic active sites. Finally, the catalytic performances of various lignin-derived catalysts are rationally assessed and compared with conventional catalysts, which involves lignin-derived solid acids for hydrolysis, hydration, dehydration(trans)esterification, multi-component reaction and condensation, lignin-derived solid base for Knoevenagel reaction, lignin-derived electro-catalysts for electro-oxidation, oxygen reduction reaction, and lignin-derived supported transition metal catalysts for hydrogenation, oxidation, coupling reaction, tandem reaction, condensation reaction, ring-opening reaction, Friedel-Crafts-type reaction,Fischer–Tropsch synthesis, click reaction, Glaser reaction, cycloaddition and(trans)esterification. The above lignin-derived catalysts thus successfully promote the transformations of organic compounds, carbon dioxide, biomass-based cellulose, saccharide and vegetable oil into valuable chemicals and fuels. At the end of this review, some perspectives are given on the current issues and tendency on the lignin-derived catalysts for green chemistry.

关键词： Catalyst Green chemistry Lignin Pretreatment Synthesis

Structural characteristics of the SARS-CoV-2 Omicron lineages BA.1 and BA.2 virions

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Signal Transduction and Targeted Therapy 2023年第4期8卷 1381-1383页

作者： Xiaoyu Ma Yanqun Wang Yuanzhu Gao Yiliang Wang An Yan Jiantao Chen Lu Zhang Peiyi Wang Jincun Zhao Zheng Liu Cryo-electron Microscopy Center Southern University of Science and TechnologyShenzhenGuangdongChina State Key Laboratory of Respiratory Disease National Clinical Research Center for Respiratory DiseaseGuangzhou Institute of Respiratory Healththe First Affiliated Hospital of Guangzhou Medical UniversityGuangzhouGuangdongChina Health and Quarantine Laboratory Guangzhou Customs District Technology CentreGuangzhouChina guangzhou Laboratory Bio-IslandGuangzhouChina Institute of Infectious disease Guangzhou Eighth People’s Hospital of Guangzhou Medical UniversityGuangzhouGuangdongChina

Dear Editor,Variants of concern(VOCs)of SARS-CoV-2 have increased transmissibility,virulence,and *** emergence of new VOCs continues to pose great challenges to public *** detailed structures of the intact Omicron viruses remain *** this study,we report the architecture of both Omicron BA.1 and BA.2 lineages using cryo-electron tomography(cryo-ET).The subtomogram averaging of viral spikes,in both pre-fusion and postfusion conformations are also investigated.

关键词： characteristics Omi resistance.

Mixing states and secondary formation processes of organic nitrogen-containing single particles in guangzhou,China

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Journal of Environmental Sciences 2024年第4期138卷 62-73页

作者： Lijun Yun Chunlei Cheng Suxia Yang Zaihua Wang Mei Li Qi En Zhong LiyuanMao Sulin Liu Xiaoya Cheng Duanying Chen Fan Yang Zhen Zhou Institute of Mass Spectrometry and Atmospheric Environment Guangdong Provincial Engineering Research Center for on-line source apportionment system of air pollutionJinan UniversityGuangzhou 510632China Guangdong-Hongkong-Macao Joint Laboratory of Collaborative Innovation for Environmental Quality Guangzhou 510632China State Key Laboratory of Loess and Quaternary Geology Institute of Earth EnvironmentChinese Academy ScienceXi’an 710061China Institute for Environment and Climate Research Jinan UniversityGuangzhou 510632China Guangdong Academy of Sciences Institute of Resources Utilization and Rare Earth DevelopmentGuangzhou 510650China Environmental Monitoring Station of Pudong New district Shanghai 201200China

Organic nitrogen(ON)compounds play a significant role in the light absorption of brown carbon and the formation of organic aerosols,however,the mixing state,secondary formation processes,and influencing factors of ON compounds are still *** paper reports on the mixing state of ON-containing particles based on measurements obtained using a highperformance single particle aerosol mass spectrometer in January 2020 in *** ON-containing particles accounted for 21% of the total detected single particles,and the particle count and number fraction of the ON-containing particles were two times higher at night than during the *** prominent increase in the content of ON-containing particles with the enhancement of NO_xmainly occurred at night,and accompanied by high relative humidity and nitrate,which were associated with heterogeneous reactions between organics and gaseous NO_(x)and/or NO_(3)*** synchronous decreases in ON-containing particles and the mass absorption coefficient of water-soluble extracts at 365 nm in the afternoon may be associated with photo-bleaching of the ON species in the *** addition,the positive matrix factorization analysis found five factors dominated the formation processes of ON particles,and the nitrate factor(33%)mainly contributed to the production of ON particles at *** results of this study provide unique insights into the mixing states and secondary formation processes of the ON-containing particles.

关键词： Organic nitrogen compounds Single particles Mixing state Secondary formation Nighttime chemistry

Carbon isotopic fractionation during vaporization of low molecular weight hydrocarbons(C6–C12)

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Petroleum Science 2017年第2期14卷 302-314页

作者： Qian-Yong Liang Yong-Qiang Xiong Jing Zhao Chen-Chen Fang Yun Li Key Laboratory of Marine Mineral Resources Guangzhou Marine Geological Survey Ministry of Land and Resources Guangzhou 510760 Guangdong China State Key Laboratory of Organic Geochemistry Guangzhou Institute of Geochemistry Chinese Academy of Sciences Guangzhou 510640 Guangdong China PetroChina Research Institute of Petroleum Exploration and development Beijing 100083 China

Three series of laboratory vaporization experiments were conducted to investigate the carbon isotope fractionation of low molecular weight hydrocarbons（LMWHs）during their progressive *** addition to the analysis of a synthetic oil mixture,individual compounds were also studied either as pure single phases or mixed with *** allowed influences of mixing effects and diffusion though soil on the fractionation to be *** LMWHs volatilized in two broad behavior patterns that depended on their molecular weight and boiling *** significantly enriched the ^13C present in the remaining components of the C6–C9 fraction,indicating that the vaporization is mainly kinetically controlled;the observed variations could be described with a Rayleigh fractionation *** contrast,the heavier compounds（n-C10–n-C12）showed less mass loss and almost no significant isotopic fractionation during vaporization,indicating that the isotope characteristics remained sufficiently constant for these hydrocarbons to be used to identify the source of an oil sample,e.g.,the specific oil field or the origin of a ***,comparative studies suggested that matrix effects should be considered when the carbon isotope ratios of hydrocarbons are applied in the field.

关键词： Low molecular weight hydrocarbons Gas chromatography-isotope ratio mass spectrometry Isotope fractionation Vaporization

Vibration-reduced anxiety-like behavior relies on ameliorating abnormalities of the somatosensory cortex and medial prefrontal cortex

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Neural Regeneration Research 2024年第6期19卷 1351-1359页

作者： Afzal Misrani Sidra Tabassum Tintin Wang Huixian Huang Jinxiang Jiang Hongjun Diao Yanping Zhao Zhen Huang Shaohua Tan Cheng Long Li Yang South China Normal University-Panyu Central Hospital Joint Laboratory of Translational Medical Research Panyu Central HospitalGuangzhouGuangdong ProvinceChina School of Life Sciences Guangzhou UniversityGuangzhouGuangdong ProvinceChina School of Life Sciences South China Normal UniversityGuangzhouGuangdong ProvinceChina guangzhou Hongai Cultural development Inc.GuangzhouGuangdong ProvinceChina Yinguo Health Management Team GuangzhouGuangdong ProvinceChina College of Biophotonics South China Normal UniversityGuangzhouGuangdong ProvinceChina

Tibetan singing bowls emit low-frequency sounds and produce perceptible harmonic tones and vibrations through manual *** sounds the singing bowls produce have been shown to enhance relaxation and reduce ***,the underlying mechanism remains *** this study,we used chronic restraint stress or sleep deprivation to establish mouse models of anxiety that exhibit anxiety-like *** then supplied treatment with singing bowls in a bottomless cage placed on the top of a *** found that unlike in humans,the combination of harmonic tones and vibrations did not improve anxietylike behaviors in mice,while individual vibration components ***,the vibration of singing bowls increased the level of N-methyl-D-aspartate receptor 1 in the somatosensory cortex and prefrontal cortex of the mice,decreased the level ofγ-aminobutyric acid A(GABA)receptorα1 subtype,reduced the level of CaMKII in the prefrontal cortex,and increased the number of GABAergic *** the same time,electrophysiological tests showed that the vibration of singing bowls significantly reduced the abnormal low-frequency gamma oscillation peak frequency in the medial prefrontal cortex caused by stress restraint pressure and sleep *** from this study indicate that the vibration of singing bowls can alleviate anxiety-like behaviors by reducing abnormal molecular and electrophysiological events in somatosensory and medial prefrontal cortex.

关键词： anxiety medial prefrontal cortex parvalbumin interneuron pressure somatosensory cortex Tibetan singing bowl vibration