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Examining the Effect of Hydroalcoholic Extract of Dracaena cinnabari on Sex Hormones and Ovarian and Uterine Tissues of Rats

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World Journal of Traditional Chinese Medicine 2024年第2期10卷 213-219页

作者： Elham Najafi Bahareh Babaei Hoolari Akbar Karimi Aliasghar Pilehvarian Department of Cellular biology Genesis Evolution-Develoment Isfahan Payame Noor University IsfahanIran Department of Anatomy School of MedicineTehran University of Medical SciencesTehranIran Department of biology Group Faculty Member of Isfahan Payame Noor UniversityIsfahanIran

Introduction: Dracaena cinnabari is considered a rich source of phytochemicals used widely in traditional medicine. In the present study, the effect of D. cinnabari hydraulic extract on the reproductive system of female rats was investigated. Methods: The samples were randomly divided into four groups(six samples in each group), including three treatment groups and one control group, and all samples were kept at the same conditions. Hydraulic extract of D. cinnabari and injected intraperitoneally daily for 10 days, while physiological serum was used for injection in to the control group. After 10 days of injection, estrogen and progesterone levels were measured by enzyme immunoassay technique. After dissection, the ovaries and uterine tissues were isolated for histological examination, and tissue changes were carefully examined. Results: The results revealed that the levels of estrogen and progesterone in experimental Groups 2 and 3 had a significant increase(P < 0.001). Regarding tissue changes, a significant increase was observed in epithelial thickness(P < 0.001), number of corpus luteum(P < 0.01), and Graafian follicle(P < 0.01) in doses of 100 and 150 mg/kg. Conclusions: Based on the results, it seems that D. cinnabari extract has an effect on the ovarian follicles.

关键词： Dracaena cinnabari herbal medicine ovarian tissues reproductive sex hormones

Artificial intelligence is transforming the research paradigm of environmental science and engineering

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Environmental Science and Ecotechnology 2024年第3期19卷 1-3页

作者： Xu Wang Guangtao Fu Nan-Qi Ren State Key Laboratory of Urban Water Resource and Environment School of Civil and Environmental EngineeringHarbin Institute of TechnologyShenzhenShenzhen518055China Centre for Water Systems College of EngineeringMathematics and Physical SciencesUniversity of ExeterExeterEX44QFUnited Kingdom

Artificial intelligence(AI),particularly through its datacrunching powerhouse,machine learning(ML),is revolutionizing the way we approach high-throughput data to obtain underlying mechanisms,characterizing,forecasting,and making evidencebased decisions in many fundamental science ***,a pressing question has emerged in the scientific community in recent years:How can we effectively interpret AI algorithms and gauge their contributions to fundamental research?

关键词： has gauge forecasting

Mobility of Major and Trace Elements during the Bauxitization Processes in Ngaoundal Area (Adamawa Cameroon): Implication on Mining Perspectives

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Open Journal of Geology 2024年第1期14卷 81-100页

作者： André Sini Harouna Boukari Ondoa Augustin Désiré Balla Djetenbe Beral Salomon Wangmené Awé Simon Djakba Basga Jean Pierre Nguetnkam Department of Mining Engineering School of Geology and Mining Engineering University of Ngaoundere Ngaoundere Cameroon Department of Mining Engineering and Environment School of Mining Industry and Geology University of Abdou-Moumouni Niamey Niger Department of Earth sciences Faculty of Science University of Ngaoundere Ngaoundere Cameroon Department of Mining Engineering Saint Jerome Polytechnic Saint Jerome Catholic University Institute of Douala Douala Cameroon Institute of agricultural Research for Development (IRAD) Garoua Cameroon

This study was focused to assess major and trace elements in bauxitic duricrusts from Ngaoundal and its surroundings in order to establish their mining interest. To this end, fieldworks, mineralogical and geochemical analyses were carried out. Four facies of duricrust were identified and characterized from the summit to the top of the slope of the Ngaoundal mountain: scoriaceous, pisolitic, nodular and massive. Mineralogical and geochemical analyses performed on 16 samples, revealed a significant concentration of Al2O3 mainly in the scoriaceous facies (over 45% in grade), moderate in Fe2O3 (averaging 23.69%) and SiO2 (averaging 21.7%). Trace elements were generally low, excluding Cr (421 ppm on average), Zr (327 ppm on average and V (213 ppm on average). In addition, the limited quantities of alkalis (Na2O, K2O) and alkaline earths metals (MgO, CaO) coupled with the very high values of Chemical Index of Alteration (CIA) and Mineralogical Index of Alteration (MIA), (more than 99%) attest to the intense weathering of the studied materials. Allitization and monosiallitization constituted the crystallochemical phenomena that have led to the development of bauxitic minerals. More than 90% of gibbsite in scoriaceous facies, 52.21% - 76.01% of kaolinite in pisolitic facies and more than 40% of hematite in nodular facies were quantified. The relationships between the constitutive components indicated their interdependency during the bauxitization phenomenon. The mineralogical and geochemical properties highlighted the mining interest of the studied duricrusts to be valorized.

关键词： Duricrust Bauxitization Phenomenon Mineralogical and Geochemical Characterization Major and Trace Elements Mining Potential

ENSO impacts on litter stocks and water holding capacity in secondary forests in eastern Amazonia

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Journal of Forestry Research 2024年第1期35卷 83-89页

作者： Julia Isabella de Matos Rodrigues Walmer Bruno Rocha Martins Victor Pereira de Oliveira Myriam Suelen da Silva Wanzerley Hélio Brito dos Santos Júnior Francisco de Assis Oliveira graduate Program in Forestry sciences Av.Presidente Tancredo Neves2501BelémPará66077-530Brazil Federal Rural University of Amazonia Av.Presidente Tancredo Neves2501BelémPará66077-530Brazil Federal Rural University of Amazonia Tv.Pau-AmareloCapitão PoçoPará68650-000Brazil National Institute of Amazonia Research Av.Constelação Cruzeiro do SulManausAmazonas 69060-062Brazil

Among the impacts of climate change,there is the intensification of phenomena such as the El Niño South-ern Oscillation(ENSO)responsible for El Niño and La Niñ***,understanding their effects on the functional pro-cesses of forests is ***,this study evaluated the effects of ENSO on litter stock and water holding capac-ity(WHC)in a successional forest in eastern *** occurred in periods with the most rainfall in El Niño(2019)and least in La Niña(2021)*** permanent plots were used to sample *** effects were evident for WHC,higher during El Niñ***,this influence was not clear for litter,as only in the rainy season effects were *** was a positive correlation of WHC with precipitation and humidity,while litter stocks were negatively correlated with temperature and wind *** the subject of this study requires long-term assessments,preliminary results suggests that,depending on the intensity of ENSO,forest functional processes can be strongly impacted and *** conclusion reinforces warnings by the scientific community about the impacts of climate change on the maintenance of litter stocks,decomposition and,consequently,the biogeochemical cycle and essential ecosystem services for the maintenance of Amazonia *** need to develop long-term research to understand the effects of climatic change on litter stocks and water holding capacity is highlighted,especially in Amazonia.

关键词： Seasonality Climate change Succession ecosystem biogeochemical cycle Amazonia biodiversity

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海水对下寒武统黑色页岩V矿化/富集的贡献

Science Bulletin 2024年第8期69卷 1006-1010页

作者：董琳慧卫炜徐林刚吝祎勃刘泽瑞潘松圻荆振华黄方 CAS Key Laboratory of Crust–Mantle Materials and Environments School of Earth and Space SciencesUniversity of Science and Technology of ChinaHefei 230026China CAS Center for Excellence in Comparative Planetology University of Science and Technology of ChinaHefei 230026China school of Earth sciences and Resources China University of GeosciencesBeijing 100083China State Key Laboratory for Mineral Deposits Research School of Earth Sciences and EngineeringNanjing UniversityNanjing 210023China Frontiers Science Center for Critical Earth Materials Cycling Nanjing UniversityNanjing 210023China school of Earth Resources China University of GeosciencesWuhan 430074China Research Institute of Petroleum Exploration and Development China National Petroleum CorporationBeijing 100083China

Early Cambrian black shales along the southern margin of the Yangtze Block are characterized by polymetallic mineralization in the lower part,including Ni-Mo sulfide ore,V ore,barite ore,phosphate ore,and"stone coal"(Fig.1a)[1,2],which were likely related to or at least coincident with the global ocean oxygenation event[3]and the radiation of early animals[4].The source of oreforming elements and the metallogenic mechanism of these polymetallic mineralization layers are highly *** models proposed include hydrothermal venting,seawater scavenging,and a combination of key mineralization factors such as terrigenous input,hydrothermal supply,seawater contribution,and impacts of clay mineral and organic matter(Fig.S1 online)[1].

关键词： mineralization hydrothermal shale

Microfluidic bubble-generator enables digital light processing 3D printing of porous structures

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Aggregate

Aggregate 2024年第1期5卷 280-291页

作者： Philipp Weber Ling Cai Francisco Javier Aguilar Rojas Carlos Ezio Garciamendez-Mijares Maria Celeste Tirelli Francesco Nalin Jakub Jaroszewicz Wojciech Swi eszkowski Marco Costantini Yu Shrike Zhang Division of Engineering in Medicine Department of MedicineBrigham and Women’s HospitalHarvard Medical SchoolCambridgeMassachusettsUSA Institute of Physical Chemistry—Polish Academy of sciences KasprzakaPoland biomaterials Group Materials Design DivisionFaculty of Materials Science and EngineeringWarsaw University of TechnologyWoloskaPoland

Three-dimensional(3D)printing is an emerging technique that has shown promising success in engineering human tissues in recent *** development of vatphotopolymerization printing modalities has significantly enhanced the complexity level for 3D printing of various functional structures and ***,the development of microfluidic chip systems is an emerging research sector with promising medical *** work demonstrates the coupling of a digital light processing(DLP)printing procedure with a microfluidic chip system to produce size-tunable,3D-printable porosities with narrow pore size distributions within a gelatin methacryloyl(GelMA)hydrogel *** is found that the generation of size-tunable gas bubbles trapped within an aqueous GelMA hydrogel-precursor can be controlled with high ***,the porosities are printed in two-dimensional(2D)as well as in 3D using the DLP *** addition,the cytocompatibility of the printed porous scaffolds is investigated using fibroblasts,where high cell viabilities as well as cell proliferation,spreading,and migration are *** is anticipated that the strategy is widely applicable in a range of application areas such as tissue engineering and regenerative medicine,among others.

关键词： 3D printing biofabrication bubble digital light processing microfluidics porous

Influence of organic matter input and temperature change on soil aggregate-associated respiration and microbial carbon use efficiency in alpine agricultural soils

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Soil Ecology Letters 2024年第3期6卷 177-188页

作者： Shuaiwen Zhang Wei Gong Xin Wan Junya Li Zhiguo Li Peng Chen Shunlin Xing Ziyan Li Yi Liu school of Ecology and Environment Tibet UniversityLhasa 850000China Key Laboratory of Aquatic Botany and Watershed Ecology Wuhan Botanical GardenChinese Academy of SciencesWuhan 430074China College of Resources and Environment Northwest A&F UniversityYangling 712100China

Understanding the dynamics of soil respiration,microbial carbon use efficiency(CUE),and temperature sensitivity(Q_(10))in response to exogenous organic matter(EOM)input,soil aggregate size,and incubation temperature is crucial for predicting soil carbon cycling responses to environmental *** this study,these interactions were investigated by 180-day incubation of soil aggregates supplemented with EOM at various temperatures(5°C,15°C and 25°C).The results reveal an‘L-shaped’trend in soil respiration on the time scale across all treatments,characterized by initial rapid declines followed by *** input and higher temperatures significantly enhance respiration ***,the respiratory rates of soil aggregates of different sizes exhibit distinct patterns based on the presence or absence of *** conditions without the addition of EOM,larger aggregates show relatively lower respiration ***,in the presence of EOM,larger aggregates exhibit higher respiratory ***,Q_(10)decreases with increasing aggregate *** relationship between Q_(10)and the substrate quality index(SQI)supports the carbon quality temperature(CQT)hypothesis,highlighting SQI’s influence on Q_(10)values,particularly during later incubation *** CUE decreases with EOM input and rising ***,aggregate size plays a role in microbial CUE,with smaller aggregates exhibiting higher CUE due to enhanced nutrient *** conclusion,the intricate interplay of EOM input,aggregate size,and temperature significantly shapes soil respiration,microbial CUE,and Q_(10).These findings underscore the complexity of these interactions and their importance in modeling soil carbon dynamics under changing environmental conditions.

关键词： soil aggregates soil respiration temperature sensitivity Tibetan Plateau

Break of thermal equilibrium between optical and acoustic phonon branches of CsPbI_(3)under continuous-wave light excitation and cryogenic temperature

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Chinese Chemical Letters 2024年第7期35卷 534-537页

作者： Rongliang Deng Yihang Chen Xiaotong Fan Guolong Chen Shuli Wang Changzhi Yu Xiao Yang Tingzhu Wu Zhong Chen Yue Lin Department of Electronic Science Fujian Engineering Research Center for Solid-State LightingXiamen UniversityXiamen 361005China Innovation Laboratory for sciences and Technologies of Energy Materials of Fujian Province(IKKEM) Xiamen 361102China Institute of Electromagnetics and Acoustics School of Electronic Science and EngineeringXiamen UniversityXiamen 361005China

The kinetic of low-temperature carrier and lattice of lead-halide perovskite is yet to be fully *** this work,we investigate the steady-state photoluminescences(PLs)of CsPbI_(3)at the environmental temperature(Te)ranging from 20 K to 300 K,and observed anomalous behaviors at cryogenic temperatures:The carrier temperature(Tc)of pure CsPbI_(3)exhibits a negative correlation with Te,accompanied by an expansion in Urbach tails of absorption spectra(Abs.)and excessive red-shifts at peak energy of *** phenomena are also observed in those samples containing a certain amount of Cs_(4)PbI_(6),but to a lesser extent and occurs at lower *** is attributed to the intensified hot phonon bottleneck effect(HPB)in CsPbI_(3)at cryogenic Te,which hinders the energy transfer from hot carriers,via longitudinal optics(LO)phonons to longitudinal acoustic(LA)phonons,to the *** samples under continuous-wave laser excitation,in specific,the barrier induced by the enhanced HPB at low Teprevents the effective thermalization among carriers,LO and LA phonons,which,therefore,form thermally isolated ensembles with different *** cryogenic Terange,the elevated temperatures of carrier and LO phonon expand the high-energy side of PLs and the low-energy tail of Abs.,*** those samples in which the CsPbI_(3)is mixed with Cs_(4)PbI_(6),the interfacial LO-LO interaction across them provides a bypass for heat dissipation,mitigating the heat accumulation in LO-phonons of CsPbI_(3).The results suggest that a strong HPB effect may break the thermal equilibrium among different branches of phonons in the lattice under certain extreme conditions.

关键词： CsPbI_(3) Cs_(4)PbI_(6) Low-temperature carrier Lattice kinetic Hot phonon bottleneck effect Interfacial LO-LO interaction

Pectolinarin inhibited LPS-stimulated inflammation in microglial BV_(2) cells via NF-κB signaling pathway

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Traditional Medicine Research 2024年第6期9卷 12-18页

作者： Bin-Feng Cheng Xiao Feng Yu-Qian Dong Shao-Qin Jian Hao-Heng Yu Jing-Jing Li Ting Ma Jun Zhang Yao-Dong Zhang Hai-Jie Yang Lei Wang Xinxiang Key Laboratory of Stress Cell biology School of Life Sciences and TechnologyXinxiang Medical UniversityXinxiang 453003China Henan Neural Development Engineering Research Center Henan Children’s HospitalZhengzhou 410000China

Background:Neuro-inflammation is regarded as one of the critical pathogenesis in neurodegenerative diseases,which is characterized by the activated microglial ***(Pec),a natural flavonoid that exists in many Chinese herbal medicines,has been reported to have various biological ***,the effects and mechanisms on neuro-inflammation are not ***:In this study,the inhibitory effects and mechanisms of Pec on neuro-inflammation were investigated in the LPS-stimulated microglial BV_(2) ***_(2) microglial cells were treated with Pec or vehicle,followed by ***-linked immunosorbent assay,real-time quantitative PCR,nitric oxide and reactive oxygen species assay,and western blot were performed to examine the effects of Pec on neuro-inflammatory ***:We showed that Pec significantly inhibited the expression of tumor necrosis factorαand interleukin 6 in mRNA and protein levels induced by ***,the production of nitric oxide,iNOS,reactive oxygen species,and COX-2 were suppressed by Pec in LPS-stimulated microglial BV_(2) *** addition,Pec inhibited LPS-induced inflammation via nuclear factor kappa B signaling pathway,as evidenced by the reduction of the phosphorylation of inhibitor of nuclear factor kappa-B kinase,the degradation of IκBα,and the nuclear translocation of ***:Taken together,Pec exhibited anti-inflammatory effects in LPS-stimulated microglial BV_(2) cells via nuclear factor kappa B signaling pathway,which might provide therapeutic potential for neuro-inflammation and neurodegenerative diseases.

关键词： neuroinflammation microglial cells pectolinarin NF-κB