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Effectiveness of mindfulness-based interventions on the well-being of healthcare workers:a systematic review and meta-analysis

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General Psychiatry 2024年第3期37卷 335-344页

作者： Natasha Yixuan Ong Finn Jing Jie Teo Jane Zi Ying Ee Chun En Yau Julian Thumboo Hiang Khoon Tan Qin Xiang Ng NUS Yong Loo Lin School of Medicine National University of SingaporeSingapore Health Services Research Unit Singapore General HospitalSingapore SingHealth Duke-NUS Medicine Academic Clinical programme Duke-NUS Medical SchoolSingapore Singhealth Duke-NUS global Health Institute Singapore Duke global Health Institute Duke UniversityDurhamNorth CarolinaUSA Division of Surgery and Surgical Oncology Singapore General HospitalSingapore Saw Swee Hock School of Public Health National University of Singapore and National University Health SystemSingapore

Background Growing evidence attests to the efficacy of mindfulness-based interventions(MBIs),but their effectiveness for healthcare workers remains *** To evaluate the evidence for MBIs in improving healthcare workers’psychological *** A systematic literature search was conducted on Medline,Embase,Cumulative Index for Nursing and Allied Health Literature,PsycINFO and Cochrane Central Register of Controlled Trials up to 31 August 2022 using the keywords‘healthcare worker’,‘doctor’,‘nurse’,‘allied health’,‘mindfulness’,‘wellness’,‘workshop’and‘program’.Randomised controlled trials with a defined MBI focusing on healthcare workers and quantitative outcome measures related to subjective or psychological well-being were eligible for inclusion.R V.4.0.3 was used for data analysis,with the standardised mean difference as the primary outcome,employing DerSimonian and Laird’s random effects *** of Recommendations,Assessment,Development and Evaluation framework was used to evaluate the quality of ***’s Risk of Bias 2 tool was used to assess the risk of bias in the included *** A total of 27 studies with 2506 participants were included,mostly from the USA,involving various healthcare *** such as stress reduction programmes,apps,meditation and training showed small to large effects on anxiety,burnout,stress,depression,psychological distress and job strain outcomes of the *** effects were also seen in self-compassion,empathy,mindfulness and ***,long-term outcomes(1 month or longer postintervention)varied,and the effects were not consistently *** MBIs offer short-term benefits in reducing stress-related symptoms in healthcare *** review also highlights limitations such as intervention heterogeneity,reduced power in specific subgroup analyses and variable study quality.

关键词： nurse sustained workers

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Computed tomography imaging and clinical significance of bacterium-positive pulmonary tuberculosis complicated with diabetes

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World Journal of Clinical Cases 2024年第20期12卷 4230-4238页

作者： Xue-Song Rong Chao Yao Section 6 Department of TuberculosisAnhui Chest HospitalHefei 230022Anhui ProvinceChina

BACKGROUND The increasing prevalence of tuberculosis(TB)and diabetes on a global scale poses a significant health challenge,particularly due to their co-occurrence,which amplifies the severity,recurrence and mortality rates associated with both *** highlights the need for further investigation into their *** To explore the computed tomography(CT)imaging and clinical significance of bacterium-positive pulmonary TB(PTB)combined with *** There were 50 patients with bacterium-positive PTB and diabetes,and 50 with only bacterium-positive *** latter were designated as the control *** CT imaging of the two groups of patients was compared,including lesion range,shape,density and *** No significant differences were observed in age,gender,smoking and drinking history,high blood pressure,hyperlipidemia and family genetic factors between the ***,compared to the patients diagnosed solely with simple bacterium-positive PTB,those with concurrent diabetes showed a wider range of lesions and more complex and diverse morphology on CT *** them,intrapulmonary tuberculosis lesions were often accompanied by manifestations of pulmonary infection,such as cavity formation and *** the same time,diabetes-related signs were often seen on CT images,such as pulmonary infection combined with diabetic pulmonary *** regression analysis identified age and medical history as significant factors influencing the degree of pulmonary infection and CT imaging outcomes in patients with both TB and *** suggests that older age and specific medical histories may increase the risk or severity of pulmonary damage in these *** CT imaging reveals more complex lesions in PTB patients with diabetes,emphasizing the need for careful evaluation and comprehensive analysis to enhance diagnostic accuracy.

关键词： Bacteria-positive pulmonary tuberculosis Diabetes Computed tomography Bronchiectasis

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Is convenience really king? Comparative evaluation of catastrophic costs due to tuberculosis in the public and private healthcare sectors of Viet Nam: a longitudinal patient cost study

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贫困所致传染病(英文) 2024年第2期13卷 1-12页

作者： Nguyen Hoa Binh Quang Vo Luan Nguyen Forse Rachel Jeanette Wiemers Anja Maria Christine Huynh Huy Ba Dong Thuy Thi Thu Phan Yen Thi Hoang Creswell Jacob Dang Thi Minh Ha Nguyen Lan Huu Shedrawy Jad L?nnroth Knut Nguyen Tuan Dinh Van Dinh Luong Annerstedt Kristi Sidney Codlin Andrew James National Lung Hospital Ha Noi Viet Nam Friends for International TB Relief Ha Noi Viet Nam Department of global Public Health WHO Collaboration Centre On Tuberculosis and Social Medicine Karolinska Institute Stockholm Sweden Stop TB Partnership Geneva Switzerland Pham Ngoc Thach Hospital Ho Chi Minh City Viet Nam

Background In Viet Nam, tuberculosis (TB) represents a devastating life-event with an exorbitant price tag, partly due to lost income from daily directly observed therapy in public sector care. Thus, persons with TB may seek care in the private sector for its flexibility, convenience, and privacy. Our study aimed to measure income changes, costs and catastrophic cost incurrence among TB-affected households in the public and private *** Between October 2020 and March 2022, we conducted 110 longitudinal patient cost interviews, among 50 patients privately treated for TB and 60 TB patients treated by the National TB Program (NTP) in Ha Noi, Hai Phong and Ho Chi Minh City, Viet Nam. Using a local adaptation of the WHO TB patient cost survey tool, participants were interviewed during the intensive phase, continuation phase and post-treatment. We compared income levels, direct and indirect treatment costs, catastrophic costs using Wilcoxon rank-sum and chi-squared tests and associated risk factors between the two cohorts using multivariate *** The pre-treatment median monthly household income was significantly higher in the private sector versus NTP cohort (USD 868 vs USD 578;P=0.010). However, private sector treatment was also significantly costlier (USD 2075 vs USD 1313;P=0.005), driven by direct medical costs which were 4.6 times higher than costs reported by NTP participants (USD 754 vs USD 164;P<0.001). This resulted in no significant difference in catastrophic costs between the two cohorts (Private: 55% vs NTP: 52%;P=0.675). Factors associated with catastrophic cost included being a single-person household [adjusted odds ratio [(aOR=13.71; 95% confidence interval (CI): 1.36–138.14;P=0.026], unemployment during treatment (aOR=10.86; 95%CI: 2.64–44.60;P<0.001) and experiencing TB-related stigma (aOR=37.90; 95%CI: 1.72–831.73;P=0.021).Conclusions Persons with TB in Viet Nam face similarly high risk of catastrophic costs whether treated in the

关键词： tuberculosis Patient cost Catastrophic cost Private sector Comparative analysis Viet Nam

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A cross-sectional analysis of the effectiveness of a nutritional support programme for people with tuberculosis in Southern Madagascar using secondary data from a non-governmental organisation

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Infectious Diseases of Poverty 2024年第1期13卷 101-102页

作者： Mara Anna Franke Julius Valentin Emmrich Fierenantsoa Ranjaharinony Onja GbrilleRavololohanitra Harizaka Emmanuel Andriamasy Samuel Knauss Nadine Muller global Digital Health Lab at Charité Center for global Health Charité – Universitätsmedizin Berlin Berlin Germany London School of Hygiene and Tropical Medicine London UK Ärzte Für Madagaskar E.V. Leipzig Germany Heidelberg Institute of global Health Heidelberg University Heidelberg Germany Berlin Institute of Health at Charité - Universitätsmedizin Berlin Berlin Germany Doctors for Madagascar Antananarivo Madagascar Speciality Network: Infectious Diseases and Respiratory Medicine Charité - Universitätsmedizin Berlin Berlin Germany

Background There is a strong,bi-directional link between tuberculosis(TB)and undernutrition:TB often causes undernutrition,and undernourished people are more likely to contract TB and experience worse ***,several TB nutritional support programmes exist;however,evidence on their effectiveness is limited and *** study evaluates the effect of a nutritional support programme implemented for people with TB in the Atsimo-Andrefana region,Madagascar in *** this programme,undernourished people with TB[with a body mass index(BMI)ofprogramme falls short of sufficiently increasing the BM

关键词： tuberculosis Sub-Saharan Africa Undernutrition Nutritional support

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The importance of post-COVID condition phenotypes characterization to decipher the mechanisms underlying this post-viral syndrome

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World Journal of Pediatrics 2024年第6期20卷 633-634页

作者： Jon Izquierdo-Pujol Sara Moron-Lopez IrsiCaixa and Institute for Health Science Research Germans Trias i Pujol(IGTP) Can Ruti CampusBadalonaSpain Biomedicine doctoral programme Faculty of BiologyUniversity of BarcelonaBarcelonaSpain CIBERINFEC MadridSpain

The coronavirus disease-19(COVID-19)outbreak,caused by the severe acute respiratory syndrome coronavirus 2(SARS-CoV-2),was declared a global pandemic in March *** has affected over 700 million people worldwide and resulted in almost 7 million deaths,equating to a 1%mortality *** present,the majority of COVID-19 cases are either asymptomatic or mild,typically resolving within two ***,between 1%and 10%of COVID-19 survivors do not fully recover and experience a post-viral syndrome referred to as"long COVID","post-acute COVID-19 syndrome"(PASC),or"post-COVID condition"(PCC).This post-viral syndrome affects both adult and pediatric ***,most of the studies published to date evaluate the adult population,leaving a gap in our understanding of its impact on children and adolescents.

关键词： acute mortality respiratory

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Patient Delay in the Diagnosis of Pulmonary tuberculosis in the Elderly—China,2015-2023

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China CDC weekly 2024年第42期6卷 1075-1079页

作者： Yushu Liu Mingkuan Fan Yuhong Li Jiaojie Kang Ybryim A Tianxin Yan Jun Cheng Hui Zhang National Center for tuberculosis Control and Prevention ChineseCenter for Disease Control and PreventionBeijingChina Medical College of Xiangyang Polytechnic Xiangyang CityHubei ProvinceChina National Key Laboratory of Intelligent Tracking and Forecasting for Infectious Diseases Chinese Center for Disease Control and PreventionBeijingChina

What is already known about this topic?Patient delay in seeking medical care for pulmonary tuberculosis(PTB),especially among elderly individuals with weakened immune systems and mild symptoms,not only slows their recovery but also increases the risk of tuberculosis spread because cases are not identified *** is added by this report?In China,patient delays experienced by elderly PTB patients showed a modest decrease from 2015 to ***,longer patient delays were observed among agricultural workers and those identified through passive case-finding ***,the patient delay in the western regions was longer than in the eastern and central *** are the implications for public health practice?The study underscores the imperative of accessible healthcare for the elderly to minimize patient delay in pulmonary tuberculosis diagnosis and treatment.

关键词： tuberculosis diagnosis prompt

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Ki-67 Change in Anthracyline-containing Neoadjuvant Chemotherapy Response in Breast Cancer

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Current Medical Science 2024年第1期44卷 156-167页

作者： Zi-guo YANG Le-hao REN Feng WANG Pi-lin WANG Wen-yan WANG Shu-ye LIN Department of General Surgery Beijing Tiantan HospitalCapital Medical UniversityBeijing 100070China Department of Critical Care Medicine Union HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhan 430022China Cancer Research Center Beijing Chest HospitalCapital Medical University/Beijing Tuberculosis and Thoracic Tumor Research InstituteBeijing 101149China

Objective Anthracycline-containing regimens are irreplaceable in neoadjuvant chemotherapy(NAC)for breast cancer(BC)at ***,30% of early breast cancer(EBC)patients are resistant to anthracycline-containing chemotherapy,leading to poor prognosis and higher ***-67 is associated with the prognosis and response to therapy,and it changes after *** A total of 105 BC patients who received anthracycline-containing NAC were ***,the optimal model of Ki-67 was selected,and its predictive efficacy was ***(IHC)was used to determine the estrogen receptor(ER),progesterone receptor(PR),and human epidermal growth factor receptor 2(HER-2)status and Ki-67 *** in situ hybridization(FISH)was used to verify the HER-2 when the IHC score was 2+.Results The post-NAC Ki67 level after treatment with anthracycline drugs was lower than pre-NAC Ki-67(19.6%±23.3%vs.45.6%±23.1%,P<0.001).Furthermore,patients with the Ki-67 decrease had a border line higher pathological complete response(pCR)rate(17.2%vs.0.0%,P=0.068),and a higher overall response rate(ORR)(73.6%vs.27.8%,P<0.001),when compared to patients without the Ki-67 *** ΔKi-67 and ΔKi-67%were valuable markers for the prediction of both the pCR rate and *** area under the curve(AUC)for ΔKi-67 on pCR and ORR was 0.809(0.698-0.921)and 0.755(0.655-0.855),respectively,while the AUC for ΔKi-67% on pCR and ORR was 0.857(0.742-0.972)and 0.720(0.618-0.822),*** logistic regression model 1 revealed thatΔKi-67 was an independent predictor for both pCR[odds ratio(OR)=61.030,95% confidence interval(CI)=4.709-790.965;P=0.002]and ORR(OR=10.001,95%CI:3.044-32.858;P<0.001).Multivariate logistic regression model 2 revealed thatΔKi-67%was also an independent predictor for both pCR(OR=408.922,95%CI=8.908-18771.224;P=0.002)and ORR(OR=5.419,95%CI=1.842-15.943;P=0.002).Conclusions The present study results suggest thatΔKi67 andΔKi67%are candidate predictor

关键词： breast cancer change in Ki-67 neoadjuvant chemotherapy anthracycline,response

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Regional Climate Damage Quantification and Its Impacts on Future Emission Pathways Using the RICE Model

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Advances in Atmospheric Sciences 2024年第9期41卷 1843-1852页

作者： Shili YANG Wenjie DONG Jieming CHOU Yong ZHANG Weixing ZHAO Beijing Meteorological Observation Centre Beijing Meteorological BureauBeijing 100089China School of Atmospheric Sciences Sun Yat-sen UniversityZhuhai 519082China Southern Marine Science and Engineering Guangdong Laboratory Zhuhai 519082China Beijing Normal University Beijing 100101China CMA Institute for Development and programme Design Beijing 100081China

This study quantified the regional damages resulting from temperature and sea level changes using the Regional Integrated of Climate and Economy(RICE)model,as well as the effects of enabling and disabling the climate impact module on future emission *** highlight varied damages depending on regional economic development and ***,China and Africa could suffer the most serious comprehensive damages caused by temperature change and sea level rise,followed by India,other developing Asian countries(OthAsia),and other high-income countries(OHI).The comprehensive damage fractions for China and Africa are projected to be 15.1%and 12.5%of gross domestic product(GDP)in 2195,with corresponding cumulative damages of 124.0 trillion and 87.3 trillion United States dollars(USD)from 2005 to 2195,***,the comprehensive damage fractions in Japan,Eurasia,and Russia are smaller and projected to be lower than 5.6%of GDP in 2195,with cumulative damages of 6.8 trillion,4.2 trillion,and 3.3 trillion USD,***,coastal regions like Africa,the European Union(EU),and OHI show comparable damages for sea level rise and temperature *** China,however,sea level-induced damages are projected to exceed those from temperature ***,this study indicates that switching the damage modules on or off affects the regional and global emission trajectories,but the magnitude is relatively *** 2195,global emissions under the experiments with all of the damage modules switched off,only the sea level damage module switched on,and only the temperature damage module switched on,were 3.5%,2.3%and 1.2%higher than those with all of the damage modules switched on,respectively.

关键词： climate damage integrated assessment model carbon emissions sea level rise temperature change

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Need for operational simplicity and timely disbursal of benefits—a qualitative exploration of the implementation of a direct benefit transfer scheme for persons with tuberculosis in India

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Infectious Diseases of Poverty 2024年第3期13卷 58-72页

作者： Malu Mohan Jeromie W.V.Thangaraj Sumit Pandey G.Sri Lakshmi Priya Sivavallinathan Arunachalam Rahul Sharma Hemant Deepak Shewade B.Aishwarya K.Afeeq Afsana Khatoon B.Gokulvijay Gude Sireesha Kavita Chandra S.Nandhakumar Prince Samuel C.Nanditha Viswanathan Devika Shanmugasundaram Raghuram Rao Manoj V.Murhekar Kathiresan Jeyashree Indian Council of Medical Research-National Institute of Epidemiology R-127TNHBAyapakkamChennaiTamil Nadu 600077India TB Support Network WHO Country Office for IndiaNew DelhiIndia Central tuberculosis Division Government of IndiaNew DelhiIndia

Background Ni-kshay Poshan Yojana(NPY)is a direct benefit transfer scheme of the Government of India introduced in 2018 to support the additional nutritional requirements of persons with TB(PwTB).Our recent nationwide evaluation of implementation and utilization of NPY using programmatic data of PwTB from nine randomly selected Indian states,reported a 70%coverage and high median delay in benefit *** undertook a qualitative study between January and July 2023,to understand the detailed implementation process of NPY and explore the enablers and barriers to effective implementation and utilization of the NPY *** We followed a grounded theory approach to inductively develop theoretical explanations for social phenomena through data generated from multiple *** conducted 36 in-depth interviews of national,district and field-level staff of the National tuberculosis Elimination programme(NTEP)and NPY beneficiaries from 30 districts across nine states of India,selected using theoretical *** analytical framework developed through inductive coding of a set of six interviews,guided the coding of the subsequent *** and themes emerged through constant comparison and the data collection continued until theoretical *** Stakeholders perceived NPY as a beneficial *** political commitment from the state administration,mainstreaming of NTEP work with the district public healthcare delivery system,availability of good geographic and internet connectivity and state-specific grievance redressal mechanisms and innovations were identified as enablers of ***,the complex,multi-level benefit approval process,difficulties in accessing banking services,perceived inadequacy of benefits and overworked human resources in the NTEP were identified as barriers to implementation and *** The optimal utilization of NPY is enabled by strong political commitment and challenged by its length

关键词： National tuberculosis Elimination programme Nutritional status Direct benefit transfer Implementation Cash transfer scheme Grounded theory India

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Reply to “Beyond microbial carbon use efficiency”

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National Science Review 2024年第4期11卷 35-37页

作者： Feng Tao Johannes Lehmann Ying-Ping Wang Lifen Jiang Bernhard Ahrens Kostiantyn Viatkin Stefano Manzoni Benjamin Z.Houlton Yuanyuan Huang Xiaomeng Huang Yiqi Luo Department of Ecology and Evolutionary Biology Cornell University Soil and Crop Sciences Section School of Integrative Plant ScienceCornell University CSIRO Environment Max Planck Institute for Biogeochemistry Department of Physical Geography and Bolin Centre for Climate Research Stockholm University Department of global Development Cornell University Key Laboratory of Ecosystem Network Observation and Modeling Institute of Geographic Sciences and Natural Resources Research Chinese Academy of Sciences Department of Earth System Science Ministry of Education Key Laboratory for Earth System Modelling Institute for Global Change Studies Tsinghua University

In their commentary, Xiao et al.[1]cautioned that the conclusions on the critical role of microbial carbon use efficiency (CUE) in global soil organic carbon (SOC) storage in the paper by Tao et al.[2] might be too *** claimed that Tao et al.’s study lacked mechanistic consideration of SOC formation and excluded important data *** et al. brought up important points,which can be largely reconciled with our findings by understanding the differences in expressing processes in empirical studies and in models.

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