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Isoscaling properties for neutron-rich fragments in highly asymmetric heavy ion collision systems

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Chinese Physics C 2024年第6期48卷 136-144页

作者：彭丹马春旺乔春源刘星泉魏慧玲 institute of Particle and Nuclear Physics College of PhysicsHenan Normal UniversityXinxiang 453007China institute of Nuclear Science and Technology Henan Academy of SciencesZhengzhou 450046China Key Laboratory of Radiation Physics and Technology of the Ministry of Education Sichuan UniversityChengdu 610064China

Traditionally,isoscaling has been interpreted and applied within the framework of the grand canonical ensemble,based on the assumption that fragment production occurs following the attainment of a statistical equilibrium ***,the influence of the symmetry energy can lead to differences in the neutron and density distribution in neutron-rich *** in turn may impact the iso scaling parameters(usually denoted byαandβ).We examine the isoscaling properties for neutron-rich fragments produced in highly asymmetric systems on inverse kinematics,namely^(40,48)Ca and ^(58,64)Ni+^(9)Be at 140 MeV per *** evaluate α and β values and sort them as a function of the neutron excess I≡*** significant differences in a extracted from fragments within different ranges of I emphasize the importance of understanding the dependence of isoscaling parameters on fragments generated in various collision ***,the|β(N)|/α(Z)value for a specific fragment in small size and highly iso spin asymmetry systems can serve as a probe to detect the variations in neutron density and proton density in different regions of the nucleus and indicate the limitations of theoretical models in investigating these issues.

关键词： isoscaling symmetry energy nuclear density neutron-rich fragment heavy ion collision

Molecular insights of exercise therapy in disease prevention and treatment

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Signal Transduction and Targeted Therapy 2024年第6期9卷 2564-2597页

作者： David Walzik Tiffany YWences Chirino Philipp Zimmer Niklas Joisten Division of Performance and Health(Sports Medicine) Institute for Sport and Sport ScienceTU Dortmund University44227 DortmundNorth Rhine-WestphaliaGermany Division of Exercise and Movement Science Institute for Sport ScienceUniversity of Göttingen37075 GöttingenLower SaxonyGermany

Despite substantial evidence emphasizing the pleiotropic benefits of exercise for the prevention and treatment of various diseases,the underlying biological mechanisms have not been fully *** exercise benefits have been attributed to signaling molecules that are released in response to exercise by different tissues such as skeletal muscle,cardiac muscle,adipose,and liver *** signaling molecules,which are collectively termed exerkines,form a heterogenous group of bioactive substances,mediating inter-organ crosstalk as well as structural and functional tissue *** scientific endeavors have focused on identifying and characterizing new biological mediators with such ***,some investigations have focused on the molecular targets of exerkines and the cellular signaling cascades that trigger adaption processes.A detailed understanding of the tissue-specific downstream effects of exerkines is crucial to harness the health-related benefits mediated by exercise and improve targeted exercise programs in health and ***,we review the current in vivo evidence on exerkine-induced signal transduction across multiple target tissues and highlight the preventive and therapeutic value of exerkine signaling in various *** emphasizing different aspects of exerkine research,we provide a comprehensive overview of(i)the molecular underpinnings of exerkine secretion,(ii)the receptor-dependent and receptor-independent signaling cascades mediating tissue adaption,and(iii)the clinical implications of these mechanisms in disease prevention and treatment.

关键词： prevention treatment collective

Polyhydroxyurethanes from Biobased Monomers and CO_(2):A Bridge between Sustainable Chemistry and CO_(2) Utilization

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Chinese Journal of Chemistry 2024年第6期42卷 652-685页

作者： Tharinee Theerathanagorn Tanika Kessaratikoon Hafeez Ur Rehman Valerio D'Elia Daniel Crespy VISTEC Advanced Laboratory for Environment-Related Inorganic and Organic Syntheses Department of Materials Science and EngineeringVidyasirimedhi Institute of Science and Technology21210Wang ChanRayongThailand Department of Materials Science and Engineering Vidyasirimedhi Institute of Science and Technology21210Wang ChanRayongThailand

Polyhydroxyurethanes(PHUs)have received considerable attention in the last decade as potential alternatives to traditional phosgene-based polyurethanes(PUs).The development of suitable 5CC(five membered-ring cyclic carbonate)precursors bearing multiple carbonate moieties(multi-5CCs)is a key requisite for preparing PHUs by polyaddition reaction with bis-or *** sustainable PHUs from CO_(2)-based five-membered cyclic carbonates(5CCs)obtained from biobased epoxides is a valuable strategy to bridge CO_(2) utilization and the upcycling of renewable *** this context,while many multi-5CC monomers reported in the literature are oil-based,recent efforts have led to the development of a large variety of multifunctional 5CCs that are produced by the combination of CO_(2) and renewable resources such as fatty acids and vegetable oils,lignin,terpenes,and *** this work,recent crucial advances(2019—2023)on PHUs prepared from bis-and multi-5CCs produced from CO_(2) and(partially/potentially)biobased substrates are reviewed with respect to their synthesis,thermal and mechanical properties,and their recent,emerging applications.

关键词： CO_(2) conversion Polyhydroxyurethanes Cyclic carbonates Biobased compounds Fatty acids Functional polymers Monomers Renewable resources

Tuning the Surface Field by Embedding Cations into Metals to Direct the Reaction Pathway of CO_(2) Electroreduction

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CCS Chemistry 2024年第3期6卷 631-640页

作者： Pei Zhang Meng Zhou Shiqiang Liu Xueqing Xing Jiahao Yang Peng Chen Yaoyu Yin Yingying Cheng Xing Tong Jun Ma Qinggong Zhu Xiaofu Sun ZhongJun Chen Xinchen Kang Buxing Han Beijing National Laboratory for Molecular Sciences CAS Laboratory of Colloid and Interface and ThermodynamicsCAS Research/Education Center for Excellence in Molecular SciencesCenter for Carbon Neutral ChemistryInstitute of ChemistryChinese Academy of SciencesBeijing 100190 Beijing Synchrotron Radiation Facility Institute of High Energy PhysicsChinese Academy of SciencesBeijing 100049 Shanghai Key Laboratory of Green Chemistry and Chemical Processes School of Chemistry and Molecular EngineeringEast China Normal UniversityShanghai 200062 School of Chemistry University of Chinese Academy of SciencesBeijing 100049

The creation of universal strategies to affect the reaction route of the electroreduction of CO_(2) is ***,we report the first work to introduce cations into diverse metals such as Cu,Bi,In,and Sn via the electroreduction of related metallic oxides in quaternary ammonium surfactant *** to their physical adsorption,cations embedded into the electrodes have a more pronounced impact on the electrical field,which effectively influences the adsorption state of *** the increase of surface field,the hydrogen evolution reaction and*COOH route are significantly reduced,favouring the*OCHO pathway *** a result,hydrogen,CO,and C_(2+)products almost completely vanish at−0.5 V versus RHE in 0.1 M Na_(2)SO_(4)in an H-type cell after enough cations are embedded into the Cu electrode,and the faradaic efficiency of formate rises from 18.0%to 99.5%simultaneously.

关键词： CO_(2)electroreduction tuneable products electrical field reaction pathway cations embedding

Multi-objective method of selecting performance-based local climatic zones using binomial logistic regression in warm and humid climate

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Frontiers of Architectural research 2024年第1期13卷 184-200页

作者： G.R.Madhavan Dorairaj Kannamma Department of Architecture National Institute of TechnologyTiruchirappalliTamil Nadu 620015India

Urban agglomeration is a serious concern due to its high energy usage and impact on the local *** countries strive to determine the development path to optimize energy *** present study aims to examine the local climatic zones(LCZs)performance in warm and humid climate through a multi-objective approach for the residential *** performance is assessed by evaluating the urban microclimate and cooling load consumption for both summer and winter months using binomial logistic *** study concludes that LCZ 2_(3)(compact mid-rise with open low-rise)and LCZ 6_(B)(open low-rise with scattered trees)perform better for 80%and 50%of total hours in warm and humid *** also proves the presence of significant performance differences between mid-rise and low-rise *** intra-zonal differences between the climatic variables are higher than the inter-zonal differences due to the impact of land surface temperature(LST).The high aspect ratio and low sky view factor of LCZ 2_(3) help the residents in that morphology in enhancing better thermal comfort and reducing cooling load *** present study contributes to building regulation policymakers by providing information on the suitable morphology for warm and humid climate.

关键词： LCZ Outdoor thermal comfort Cooling load LST and urban morphology indicators

Quality assessment of surgery for colorectal cancer:Where do we stand?

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World Journal of Gastrointestinal Surgery 2024年第4期16卷 982-987页

作者： Stefan Morarasu Cristian Livadaru Gabriel-Mihail Dimofte The Second Department of Surgical Oncology Regional Institute of OncologyIasi 707483Romania

Quality assurance in surgery has been one of the most important topics of debate among colorectal surgeons in the past *** has produced new surgical standards that led in part to the impressive oncological outcomes we see in many units *** mesorectal excision,complete mesocolic excision(CME),and the Japanese D3 lymphadenectomy are now benchmark techniques embraced by many surgeons and widely recommended by surgical ***,there are still ongoing discrepancies in outcomes largely based on surgeon *** is one of the main reasons why many countries have shifted colorectal cancer surgery only to high volume *** markers of surgical quality is thus a perquisite to ensure that standards and oncological outcomes are met at an institutional *** the evolution of CME surgery,various quality markers have been described,mostly based on measurements on the surgical specimen and lymph node yield,while others have proposed radiological markers(*** stumps)measured on postoperative scans as part of the routine cancer *** is no ideal marker;however,taken together and assembled into a new score or set of criteria may become a future point of reference for reporting outcomes of colorectal cancer surgery in research studies and defining subspecialization requirements both at an individual and hospital level.

关键词： Colorectal cancer Colon surgery Arterial stump Complete mesocolic excision Surgical quality

Genetically modified pigs with CD163 point mutation are resistant to HP-PRRSV infection

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Zoological research 2024年第4期45卷 833-844页

作者： Ying Liu Lin Yang Hong-Yong Xiang Ming Niu Jia-Cheng Deng Xue-Yuan Li Wen-Jie Hao Hong-Sheng Ou-Yang Tong-Yu Liu Xiao-Chun Tang Da-Xin Pang Hong-Ming Yuan State Key Laboratory for Diagnosis and Treatment of Severe Zoonotic Infectious Diseases Animal Genome Editing Technology Innovation CenterCollege of Animal SciencesJilin UniversityChangchunJilin 130062China Chifeng Best Genetics Technology Co. Ltd.ChifengNei Mongol 024000China Chongqing Jitang Biotechnology research institute Co. Ltd.Chongqing 400015China

Porcine reproductive and respiratory syndrome(PRRS)is a globally prevalent contagious disease caused by the positive-strand RNA PRRS virus(PRRSV),resulting in substantial economic losses in the swine *** the CD163 SRCR5 domain,either through deletion or substitution,can eff1ectively confer resistance to PRRSV infection in ***,large fragment modifications in pigs inevitably raise concerns about potential adverse effects on growth *** the impact of genetic modifications on normal physiological functions is a promising direction for developing PRRSV-resistant *** the current study,we identified a specific functional amino acid in CD163 that influences PRRSV *** infection experiments conducted on Marc145 and PK-15CD163 cells illustrated that the mE535G or corresponding pE529G mutations markedly inhibited highly pathogenic PRRSV(HP-PRRSV)proliferation by preventing viral binding and ***,individual viral challenge tests revealed that pigs with the E529G mutation had viral loads two orders of magnitude lower than wild-type(WT)pigs,confirming effective resistance to *** of the physiological indicators and scavenger function of CD163 verified no significant differences between the WT and E529G *** findings suggest that E529G pigs can be used for breeding PRRSV-resistant pigs,providing novel insights into controlling future PRRSV outbreaks.

关键词： PRRSV CD163 Point mutation E529G Pigs

Concerns Arise:Wheat Allergy Risk in Pre-packaged Food Products from China

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Food Science and Human Wellness 2024年

作者： Wenfeng Liu Jian Wang Zhongliang Wang Fangfang Min Yong Wu Juanli Yuan Jinyan Gao Hongbing Chen State Key Laboratory of Food Science and Resources Nanchang University School of Food Science and Technology Nanchang University Sino-German Joint research institute Nanchang University Jiangxi Province Key Laboratory of Food Allergy Nanchang University School of Pharmaceutical Sciences Nanchang University

Understanding and monitoring the cross-contamination of food allergens is crucial for safeguarding public health and ensuring food safety. Food allergen risk assessment， derived from classical toxicological principles， can identify and quantify the risk of allergies. This study aimed to investigate the risk of wheat allergic reactions to prepackaged foods from China through the utilization of food allergen risk assessment. A total of 575 products have been surveyed， wheat/gluten， milk and egg were major allergens labelled on products. According to voluntary incidental trace allergen labelling 3.0 (VITAL? 3.0) program， the number of products belonged to Action Level 2 were 303. Integration of PAL analysis indicated that 9.57% products would pose a potential risk to wheat allergic individuals. The probabilistic risk assessment results suggest that 7984 allergic reactions may arise among wheat-allergic consumers during 10，000 eating occasions due to the consumption of pre-packaged food products with incorrect wheat-related allergen labelling. This study demonstrated that a risk assessment-based approach can support the guidance of allergen labelling and management of food allergen for pre-packaged food products， providing protection for allergic individuals in food consumption and for food manufacturers in food production and trade.

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Application of deep learning methods combined with physical background in wide field of view imaging atmospheric Cherenkov telescopes

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Nuclear Science and Techniques 2024年第4期35卷 208-220页

作者： Ao-Yan Cheng Hao Cai Shi Chen Tian-Lu Chen Xiang Dong You-Liang Feng Qi Gao Quan-Bu Gou Yi-Qing Guo Hong-Bo Hu Ming-Ming Kang Hai-Jin Li Chen Liu Mao-Yuan Liu Wei Liu Fang-Sheng Min Chu-Cheng Pan Bing-Qiang Qiao Xiang-Li Qian Hui-Ying Sun Yu-Chang Sun Ao-Bo Wang Xu Wang Zhen Wang Guang-Guang Xin Yu-Hua Yao Qiang Yuan Yi Zhang School of Physics and Technology Wuhan UniversityWuhan 430072China School of Physics and Astronomy Yunnan UniversityKunming 650091China Ministry of Education The Key Laboratory of Cosmic Rays(Tibet University)Lhasa 850000China Key Laboratory of Particle Astrophysics Institute of High Energy PhysicsChinese Academy of SciencesBeijing 100049China University of Chinese Academy of Sciences 19 A Yuquan RoadShijingshan DistrictBeijing 100049China College of Physics Sichuan UniversityChengdu 610064China School of Intelligent Engineering Shandong Management UniversityJinan 250357China Tsung‑Dao Lee institute Shanghai Jiao Tong UniversityShanghai 200240China Suzhou Aerospace Information research institute Suzhou 215123China College of Physics Chongqing UniversityNo.55 Daxuecheng South RoadHigh‑tech DistrictChongqing 401331China Key Laboratory of Dark Matter and Space Astronomy Purple Mountain ObservatoryChinese Academy of SciencesNanjing 210008China

The High Altitude Detection of Astronomical Radiation(HADAR)experiment,which was constructed in Tibet,China,combines the wide-angle advantages of traditional EAS array detectors with the high-sensitivity advantages of focused Cherenkov *** objective is to observe transient sources such as gamma-ray bursts and the counterparts of gravitational *** study aims to utilize the latest AI technology to enhance the sensitivity of HADAR *** datasets and models with distinctive creativity were constructed by incorporating the relevant physical theories for various *** models can determine the type,energy,and direction of the incident particles after careful *** obtained a background identification accuracy of 98.6%,a relative energy reconstruction error of 10.0%,and an angular resolution of 0.22°in a test dataset at 10 *** findings demonstrate the significant potential for enhancing the precision and dependability of detector data analysis in astrophysical *** using deep learning techniques,the HADAR experiment’s observational sensitivity to the Crab Nebula has surpassed that of MAGIC and *** energies below 0.5 TeV and remains competitive with conventional narrow-field Cherenkov telescopes at higher *** addition,our experiment offers a new approach for dealing with strongly connected,scattered data.

关键词： VHE gamma-ray astronomy HADAR Deep learning Convolutional neural networks