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Effectiveness of indoor residual spraying on malaria control: a systematic review and meta-analysis

Infectious Diseases of Poverty 2022年第4期11卷 29-42页

作者： Yiguo Zhou Wan-Xue Zhang Eljah Tembo Ming-Zhu Xie Shan-Shan Zhang Xin-Rui Wang Ting-Ting Wei Xin Feng Yi-Lin Zhang Juan Du Ya-Qiong Liu Xuan Zhang Fuqiang Cui Qing-Bin Lu Department of Laboratorial Science and Technology&Vaccine Research center School of Public HealthPeking UniversityNo.38Xueyuan RoadHaidian DistrictBeijing 100191People's Republic of China Department of Public Health Emergency Management School of Public HealthPeking UniversityBejing 100191People's Republic of China institute for Hospital Management Research Chinese PLA General HospitalBeijing 100039People's Republic of China Global center for Infectious Disease and Policy Research&Global Health and Infectious Diseases Group Peking UniversityBeijing 100191People's Republic of China

Background:Indoor residual spraying(IRS)is one of the key interventions recommended by World Health Organization in preventing malaria *** aimed to conduct a systematic review and meta-analysis of global studies about the impact of IRS on malaria ***:We searched PubMed,Web of Science,Embase,and Scopus for relevant studies published from database establishment to 31 December ***-effects models were used to perform meta-analysis and subgroup analysis to pool the odds ratio(OR)and 95%confidence interval(CI).Meta-regression was used to investigate potential factors of heterogeneity across ***:Thirty-eight articles including 81 reports and 1,174,970 individuals were included in the *** was associated with lower rates of malaria infection(OR=0.35,95%CI:0.27-0.44).The significantly higher effectiveness was observed in IRS coverage≥80%than in IRS coverage<80%.Pyrethroids was identified to show the greatest performance in malaria *** addition,higher effectiveness was associated with a lower gross domestic product as well as a higher coverage of IRS and bed net ***:IRS could induce a positive effect on malaria infection *** high IRS coverage and the use of pyrethroids are key measures to reduce malaria *** efforts should focus on increasing IRS coverage,developing more effective new insecticides against malaria,and using multiple interventions comprehensively to achieve malaria control goals.

关键词： Indoor residual spraying Malaria Meta-analysis Effectiveness evaluation

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Research progress on the development mechanism and exploratory protection of the scaling off on earthen sites in NW China

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Science China(technological Sciences) 2023年第8期66卷 2183-2196页

作者： DU YuMin DONG WenQiang CUI Kai CHEN WenWu YANG WeiLi Institute of Culture and Heritage Northwestern Polytechnical UniversityXi’an 710072China Western center for Disaster Mitigation in Civil Engineering of Ministry of Education of China School of Civil EngineeringLanzhou University of TechnologyLanzhou 730050China Key Scientific Research Base of the State Administration of Cultural Heritage for the Conservation and Restoration of Murals and Material Science Research Northwestern Polytechnical UniversityXi’an 710072China Key Laboratory of Mechanics on Disaster and Environment in Western China College of Civil Engineering and MechanicsLanzhou UniversityLanzhou 730000China School of Mechanics Civil Engineering and ArchitectureNorthwestern Polytechnical UniversityXi’an 710072China

The scaling off is among the most pervasive and severe deterioration *** scaling off developed on earthen sites in Northwest China has a special and complex binary structure composed of crusted and loose *** the synergistic functions of external environmental elements such as rainfall,temperature,and wind,and rammed earth properties,this deterioration has gradually created the crust on the site’s surface,and has then evolved into exfoliation and finally fallen off,leading to the reciprocating progressive destruction of earthen ***,determining the development mechanism of scaling off and implementing targeted protection measures for the scientific conservation of earthen sites has become *** this review study,the properties of the building material causing the binary structure and the coupling effects of water,temperature,salt,and wind on the development of scaling off were determined,and the quantitative evaluation system for this deterioration development was *** interpreting the reasons for the development of the scaling off,protective measures including chemical grouting,electro-osmosis grouting,and overlay applications were *** study also pointed out the research hotspots and shortage in the study process on the scaling *** hotspots generally focused on the development mechanism of binary structure,quantitative assessment of the degree of development,and related scientific consolidation *** shortcomings around the above directions include less attention to the development characteristics and mechanism of scaling off on earthen sites under special environment types,optimization and applicability of quantitative evaluation models,and the development and feasibility of reinforcement slurries and *** study can be beneficial in providing theoretical support for the scientific conservation and engineering practice of the scaling off on the earthen sites.

关键词： scaling off earthen sites binary structure development mechanism quantitative evaluation protection

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Motivations and Training Needs of General Practitioner Preceptors

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Chinese Medical Journal 2017年第14期130卷 1689-1693页

作者： Wen Ren Nulanbieke Hasenbieke Ying Liu Yan Qiu Zhao-Nong Zhou Xiao-Yan Mao Jing-Jing Ren Department of General Practice The First Affiliated Hospital College of Medicine Zhejiang University Hangzhou Zhejiang 310003 China Training center of the National Population and Family Planning Commission Beijing 100024 China Department of Comprehensive Training School of Continuing Education Zhejiang University Hangzhou Zhejiang 310003 China

Background：General practitioner （GP） preceptors play an important role in the cultivation of *** problems exist in the training of GP *** study aimed to explore the willingness and training needs of GP preceptors and compare the differences between preceptors from general practice and other ***：A total of 375 questionnaire forms were sent to 375 GP preceptors from 11 different provinces,and 344 completed forms were *** main outcome included general information,teaching motivations,and training needs of GP ***：The study showed that about 89.2% of GP preceptors were willing to be *** majority of respondents strongly agreed that the motivation for becoming a GP supervisor was to learn from *** most important capability they should master was clinical teaching （92.2%）,followed by lecture （83.1%） and doctor-patient communication （83.1%）.The top three preferred methods of GP preceptors training were case discussion （78.8%）,workshop （57.6%）,and classroom teaching （56.4%）.The domains in which most GP preceptors wanted to acquire knowledge and skill were mental health （59.3%）,rehabilitation （47.1%）,pediatrics （41.0%）,and obstetrics （37.5%）.No significant differences were found in the willingness to train GPs （x2 =3.34,P 〉 0.05） and whether they would become or continue to become a GP supervisor after the training （x2 =l.106,P 〉 0.05）.Conclusions：Although most preceptors were under on-the-job training,they were glad to train *** be qualified,preceptors should be trained according to the actual needs of GP preceptors.

关键词： General Practitioner Health Educator: Motivation: Needs Assessment

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Short Tail:taming tail latency for erasure-code-based in-memory systems

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Frontiers of Information Technology & Electronic Engineering 2022年第11期23卷 1646-1657页

作者： Yun TENG Zhiyue LI Jing HUANG Guangyan ZHANG College of Computer Science and Technology Jilin UniversityChangchun 130012China Department of Computer Science and Technology Tsinghua UniversityBeijing 100084China Key Laboratory of Symbolic Computation and Knowledge Engineering of Ministry of Education Jilin UniversityChangchun 130012China Beijing National Research center for Information Science and Technology(Tsinghua University) Beijing 100084China

In-memory systems with erasure coding(EC)enabled are widely used to achieve high performance and data ***,as the scale of clusters grows,the server-level fail-slow problem is becoming increasingly frequent,which can create long tail *** influence of long tail latency is further amplified in EC-based systems due to the synchronous nature of multiple EC *** this paper,we propose an EC-enabled in-memory storage system called ShortTail,which can achieve consistent performance and low latency for both reads and ***,ShortTail uses a lightweight request monitor to track the performance of each memory node and identify any fail-slow ***,ShortTail selectively performs degraded reads and redirected writes to avoid accessing fail-slow ***,ShortTail posts an adaptive write strategy to reduce write amplification of small *** implement ShortTail on top of Memcached and compare it with two baseline *** experimental results show that ShortTail can reduce the P99 tail latency by up to 63.77%;it also brings significant improvements in the median latency and average latency.

关键词： Erasure code In-memory system Node fail-slow Small write Tail latency

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Arbitrarily shaped retro-reflector by optics surface transformation

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Chinese Optics Letters 2020年第10期18卷 58-62页

作者： Fei Sun Yichao Liu Yibiao Yang Zhihui Chen Sailing He Key Laboratory of Advanced Transducers and Intelligent Control System Ministry of Education and Shanxi ProvinceCollege of Physics and OptoelectronicsTaiyuan University of TechnologyTaiyuan 030024China Centre for Optical and Electromagnetic Research State Key Laboratory of Modern Optical InstrumentationNational Engineering Research Center for Optical InstrumentsZhejiang UniversityHangzhou 310058China

A novel way to design arbitrarily shaped retro-reflectors by optics surface transformation is proposed. The entire design process consists of filling an optic-null medium between the input and output surfaces of the retroreflector, on which the points have 180 deg reverse corresponding relations. The retro-reflector can be designed to be very thin(a planar structure) with high efficiency. The effective working angles of our retro-reflector are very large(from-80 deg to +80 deg), which can, in principle, be further extended. Layered metal plates and zero refractive index materials are designed to realize the proposed retro-reflector for a TM polarized beam.

关键词： retro-reflector optics surface transformation

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New classification-oriented laparoscopic anatomical hepatectomy strategy for hepatocellular carcinoma invading two or more(sub)segments in the left lobe

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Chinese Medical Journal 2022年第21期135卷 2599-2601页

作者： Haifeng Wan Tian Lan Ting Duan Kunlin Xie Jiwei Huang Jiayin Yang Yong Zeng Li Jiang Hong Wu Department of Liver Transplantation center West China Hospital of Sichuan UniversityChengduSichuan 610041China Department of Radiology West China Hospital of Sichuan UniversityChengduSichuan 610041China Department of Liver Surgery West China Hospital of Sichuan UniversityChengduSichuan 610041China

With technological advances in laparoscopic hepatectomy and new navigation devices,such as flexible laparoscopic ultrasound probes,indocyanine green(ICG)-fluorescent imaging and three-dimensional imaging,laparoscopic segmentectomy(LS),which maximizes the preservation of the functional hepatic reserve and the possibility for future repeat hepatectomy while ensuring adequate surgical margins,has become a feasible alternative to hemihepatectomy for addressing hepatocellular carcinoma(HCC).

关键词： hepatectomy laparoscopic advances

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Stimulated Raman scattering signal generation in a scattering medium using self-reconstructing Bessel beams

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Photonics Research 2020年第6期8卷 929-939页

作者： XUELI CHEN XINYU WANG LIN WANG PENG LIN YONGHUA ZHAN JI-XIN CHENG Engineering Research center of Molecular&Neuro Imaging Minitry of EducationXi'an 710126China School of Life Science and Technology Xidian UniversityXi'an 710126China School of Information Sciences and Technology Northwest UniversityXi'an 710127China Department of Electrical and Computer Engineering&Biomedical Engineering Boston UniversityBostonMassachusetts 02215USA

Scattering is a huge challenge for microscopic ***,it is difficult to observe target chemicals in scattering media by means of the current Gaussian beam-based stimulated Raman scattering(SRS)microscopy,since the tight focus of the Gaussian beam is destroyed after propagating through a certain *** beams,featuring self-reconstructing property,may bring a solution to this *** combining Bessel beams with SRS microscopy,we can probe the SRS signal from a scattering *** this paper,using the beam propagation method,we first simulate the propagation of the Bessel beam as well as the generation and self-reconstruction of SRS *** adding glass beads along the beam propagation path in order to simulate scattering,the propagation of the Bessel beams and the generation of the SRS signals will ***,we design a series of simulations to investigate the influence of the size,position,number,and distribution of the added glass beads on the generation of the SRS signals.A preliminary experiment is also carried out to confirm the simulation *** demonstrate that the SRS signals can be generated or be recovered at a certain depth in scattering media,and that such signals are greatly affected by the parameters of the scatters.

关键词： Bessel beads destroyed

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Synthesis and Hydrophilic Performance of Poly(Lactic Acid)-Poly(Ethylene Glycol) Block Copolymers

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American Journal of Analytical Chemistry 2016年第3期7卷 299-305页

作者： Gang Xu Sihao Chen Xiao Yan Chunyu Yang Zhichang Chen College of Chemistry and Chemical Engineering Shanghai University of Engineering Science Shanghai China Multidisciplinary center for Advanced Materials Shanghai University of Engineering Science Shanghai China College of School of Automotive Engineering Shanghai University of Engineering Science Shanghai China

Lactide was synthesized using lactic acid and stannous octoate as raw material and catalyst, respectively. Poly(lactic acid)-poly(ethylene glycol) (PLA-PEG) was prepared by lactide and poly (ethylene glycol) (PEG) via ring-opening polymerization. The most appropriate technological conditions of synthesis of lactide were researched in the paper. The copolymers were measured by Infrared spectroscopy (IR) and 1H nuclear magnetic resonance (1H NMR). The results proved that the lactide and PLA-PEG were synthesized successfully. Hydrophilic performance of the copolymer was measured by a water contact angle tester after prepared into a flat membrane. The water contact angle changed from 81.5? to 71.6?, which proved that the hydrophily of PLA-PEG was better than PLA.

关键词： Lactide Poly(Lactic Acid)-Poly(Ethylene Glycol) (PLA-PEG) Prepare Hydrophily

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Biomineralization of Zinc-Phosphate-Based Nano Needles by Living Microalgae

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Journal of Biomaterials and Nanobiotechnology 2012年第3期3卷 362-370页

作者： Giulia Santomauro Vesna Srot Birgit Bussmann Peter A. van Aken Franz Brümmer Horst Strunk Joachim Bill Institute for Biology Depart- ment of Zoology University of Stuttgart Stuttgart Germany 4Institute for Materials Science Chair in Material Physics University of Stuttgart Stuttgart Germany. Institute for Materials Science Chair in Chemical Material Synthesis University of Stuttgart Stuttgart Germany Institute for Materials Science University of Stuttgart Stuttgart Germany Stuttgart center for Electron Microscopy – StEM Max Planck Institute for Intelligent Systems Stuttgart Germany Stuttgart center for Electron Microscopy–StEM Max Planck Institute for Intelligent Systems Stuttgart Germany

Up to now, chemical synthesis routes only provide restricted opportunities for the formation of structured nano particles. In contrast, living microorganisms generate nano materials of well defined shapes by the precise control of biomineralization. Here we reveal new principles for the generation of functional nano materials through the process of biomineralization. We used the detoxification mechanism of the unicellular alga Scenedesmus obliquus to generate a techno logically interesting zinc-phosphate-based nano material. The algae were incubated in media with a sublethal zinc concentration (6.53 mg Zn dm-3) for 4 weeks. Using BF-and ADF-STEM imaging combined with analytical XEDS we could show that nano needles containing phosphorus and zinc were formed inside the living cells. Further more, the cells incubated with zinc show a strong fluorescence. Our findings indicate that the algae used polyphosphate bodies for detoxification of the zinc ions, leading to the generation of intracellular zinc-phosphate-based nano needles. Beside the technological application of this material, the fluorescent cells can be used for labeling of e.g. biological probes. This new experimental protocol for the production of an inorganic functional material can be applied also for other substances.

关键词： Nano Needles Biomineralization Zinc Phosphate Microalgae Fluorescence

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Two human monoclonal SARS-CoV-2 antibodies that maintain neutralizing potency against the SARS-CoV-2 Omicron BA.1 and BA.2 variants

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Genes & Diseases 2023年第3期10卷 664-667页

作者： Qianqian Zheng Liangwei Duan Zhihua Jiang Tingxuan Gu Bojie Zhang Jiaoyang Li Yang Zhang Shiyu Zhang Yinming Liang Hui Wang Henan Key Laboratory of Immunology and Targeted Drugs School of Laboratory MedicineXinxiang Medical UniversityXinxiangHenan 453003China Henan Collaborative Innovation center of Molecular Diagnosis and Laboratory Medicine Xinxiang Medical UniversityXinxiangHenan 453003China KMD Bioscience(Tianjin)Company Limited Tianjin 301723China Department of Pathophysiology School of Basic Medical SciencesAcademy of Medical ScienceCollege of MedicineZhengzhou UniversityZhengzhouHenan 450001China China-US(Henan)Hormel Cancer Institute ZhengzhouHenan 450008China

The pandemic caused by severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)continues to sweep the globe with devastating consequences on human lives and world *** an RNA virus,SARS-CoV-2 has a relatively high mutation rate and is rapidly ***,new SARS-CoV-2 variants continued to emerge,5 of which were designated by the World Health Organization(WHO)as variants of concern(VOCs),Alpha(B.1.1.7).

关键词： acute monoclonal respiratory

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