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Simultaneous detection of the shuttling motion of liquid metal droplets in channels under alternating pressure and capacitive sensor signals

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Microsystems & Nanoengineering 2024年第2期10卷 83-90页

作者： Shinji Bono Ryotaro Nakai Satoshi Konishi research Organization of Science and Technology Ritsumeikan UniversityShigaJapan Ritsumeikan Advanced research Academy KyotoJapan Ritsumeikan global Innovation research Organization Ritsumeikan UniversityShigaJapan Graduate School of Science and Engineering Ritsumeikan UniversityShigaJapan

Implementing a signal-switching mechanism for the selective use of integrated sensors and actuators plays a crucial role in streamlining the functionality of miniaturized ***,a liquid metal droplet(LMD)-based signal-switching mechanism is introduced to achieve such *** modulation with a 100-μm spatial resolution enabled precise control of the position of the LMDs within a *** integrating the channel with asymmetrically structured electrodes,the effect of the shuttle-like movement of LMD on the temporal changes in the overall capacitance was ***,analysis of the capacitive peaks revealed the directional movement of the LMDs,enabling estimation of the position of the LMDs without direct *** addition,we achieved successful signal extraction from the capacitive sensor that was linked to the activated electrodes,thereby enabling selective data *** proposed signal-switching mechanism method achieved a detection accuracy of~0.1 *** sensor’s ability to simultaneously detect the LMD position and generate a signal underscores its significant potential for multiplexing in multisensing systems,particularly in concealed environments,such as in vivo settings.

关键词： liquid thereby integrating

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Oncology research 2024年第2期32卷 421-432页

作者： SEUNG-HEE GWAK JUHYUN LEE EUNJI OH DOHYUN LEE WONSHIK HAN JONGMIN KIM KYONG-TAI KIM Department of Life Sciences Pohang University of Science and TechnologyPohang37673Korea R&D Center NovMetaPharma Co.Ltd.Pohang37668Korea Department of Surgery and Cancer research Institute Seoul National University College of MedicineSeoul03080Korea generative genomics research Center Global Green Research&Development CenterHandong Global UniversityPohang37554Korea

genetic information is transcribed from genomic DNA to mRNA,which is then translated into threedimensional *** can undergo various post-transcriptional modifications,including RNA editing that alters mRNA sequences,ultimately affecting protein *** this study,RNA editing was identified at the 499th base(c.499)of human vaccinia-related kinase 2(VRK2).This RNA editing changes the amino acid in the catalytic domain of VRK2 from isoleucine(with adenine base)to valine(with guanine base).Isoleucine-containing VRK2 has higher kinase activity than the valine-containing VRK2,which leads to an increase in tumor cell *** we reported that VRK2 directly interacts with dystrobrevin-binding protein(dysbindin)and results in reducing its ***,we demonstrate that isoleucine-containing VRK2 decreases the level of dysbindin than valinecontaining *** interacts with cyclin D and thereby regulates its expression and *** reduction in the level of dysbindin by isoleucine-containing VRK2 further enhances the cyclin D expression,resulting in increased tumor growth and reduction in survival *** has also been observed that in patient samples,VRK2 level was elevated in breast cancer tissue compared to normal breast ***,the isoleucine form of VRK2 exhibited a greater increase in breast cancer ***,it is concluded that VRK2,especially dependent on the 167th variant amino acid,can be one of the indexes of tumor progression and proliferation.

关键词： VRK2 Kinase activity Breast cancer Tumor RNA editing Cell proliferation Cell growth

Pollen analysis reveals the effects of uncovered interactions,pollen-carrying structures,and pollinator sex on the structure of wild bee-plant networks

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Insect Science 2024年第3期31卷 971-988页

作者： Clément Tourbez Carmelo Gómez-Martínez MiguelÁngel Gonzalez-Estévez Amparo Lazaro Mediterranean Institute for Advanced Studies(UIB-CSIC) Global Change Research GroupEsporlesBalearic IslandsSpain Department of Biology Ecology AreaUniversity of the Balearic/slandsPalmaSpain

Pollination networks are increasingly used to model the complexity of interactions between pollinators and flowering plants in *** methods exist to sample these interactions,with direct observations of plant-pollinator contacts in the field being by far the most *** the identification of pollen carried by pollinators allows uncovering interactions and increasing sample sizes,the methods used to build pollen-transport networks are variable and their effect on network structure remains *** understand how interaction sampling influences the structure of networks,we analyzed the pollen found on wild bees from eight communities across Mallorca Island and investigated the differences in pollen loads between bee body parts(scopa ***)and *** then assessed how these differences,as well as the uncovered interactions not detected in the field,influenced the structure of wild bee-plant *** identified a higher quantity and diversity of pollen in the scopa than in the rest of the female body,but these differences did not lead to differences in structure between plant-pollination(excluding scopa pollen)and bee-feeding interaction(including scopa pollen)***,networks built with pollen data were richer in plant species and interactions and showed lower modularity and specialization(H2'),and higher nestedness than visitation networks based on field *** interactions with plants were stronger compared to those of males,although not ***,females were more generalist(low d')and tended to be more central in interaction networks,indicating their more key role structuring pollination networks in comparison to *** study highlights the importance of palynological data to increase the resolution of networks,as well as to understand important ecological questions such as the differences between plant-pollination and bee-feeding interaction networks,and the role of sexes in pollination.

关键词： palynology pollen-transport networks pollination role of bee sexes sampling methodology visitation networks

Fully Decoupled Branch Energy Balancing Control Method for Modular Multilevel Matrix Converter Based on Sequence Circulating Components

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CSEE Journal of Power and Energy Systems 2024年第1期10卷 235-247页

作者： Zexin Zhao Weijiang Chen Zhichang Yang Guoliang Zhao Bin Han Yunfei Xu Nianwen Xiang Shulai Wang China Electric Power research Institute Beijing 100192China State Grid Corporation of China Beijing 100031China State Grid Smart Grid research Institute Beijing 102209China State Key Laboratory of Advanced Power Transmission Technology Global Energy Interconnection Research InstituteBeijing 102211China Hefei University of Technology Hefei 230009China

The modular multilevel matrix converter(M3C)is a potential frequency converter for low-frequency AC ***,capacitor voltage control of high-voltage and largecapacity M3C is more difficult,especially for voltage balancing between *** solve this problem,this paper defines sequence circulating components and theoretically analyzes the influence mechanism of different sequence circulating components on branch capacitor voltage.A fully decoupled branch energy balancing control method based on four groups of sequence circulating components is *** method can control capacitor voltages of nine branches in horizontal,vertical and diagonal *** influences of both circulating current and voltage,a cross decoupled control is designed to improve control *** results are taken from a low-frequency transmission system based on PSCAD/EMTDC,and effectiveness and precision of the proposed branch energy balancing control method are verified in the case of nonuniform parameters and an unbalanced power system.

关键词： Branch energy balancing control decoupled control low-frequency AC transmission modular multilevel matrix converter(M3C) sequence circulating components

Nonlinear relationship between urban form and transport CO_(2)emissions:Evidence from Chinese cities based on machine learning

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Journal of geographical Sciences 2024年第8期34卷 1558-1588页

作者： LI Linna DENG Zilin HUANG Xiaoyan Faculty of geographical Science Beijing Normal UniversityBeijing 100875China Northwest Land and Resources research Center Global Regional and Urban Research InstituteShaanxi Normal UniversityXi'an 710119China

Reducing carbon emissions from the transport sector is essential for realizing the carbon neutrality goal in *** substantial studies on the influence of urban form on transport cO_(2)emissions,most of them have treated the effects as a linear process,and few have studied their nonlinear *** research focused on 274 Chinese cities in 2019 and applied the gradient-boosting decision tree(GBDT)model to investigate the nonlinear effects of four aspects of urban form,including compactness,complexity,scale,and fragmentation,on urban transport CO_(2)*** was found that urban form contributed 20.48%to per capita transport CO_(2)emissions(PTCEs),which is less than the contribution of socioeconomic development but more than that of transport *** contribution of urban form to total transport CO_(2)emissions(TCEs)was the lowest,at 14.3%.In particular,the effect of compactness on TCEs was negative within a threshold,while its effect on PTCEs showed an inverted U-shaped *** effect of complexity on PTCEs was positive,and its effect on TCEs was *** effect of scale on TCEs and PTCEs was positive within a threshold and negative beyond that *** effect of fragmentation on TCEs was also nonlinear,while its effect on PTCEs was positively *** results show the complex effects of the urban form on transport CO_(2)***,strategies for optimizing urban form and reducing urban transport carbon emissions are recommended for the future.

关键词： urban form transport CO,emissions nonlinear effect sustainable transport gradient-boosting decision treemodel

Effects of nitrogen and phosphorus additions on soil nematode community of soybean farmland

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Soil Ecology Letters 2024年第2期6卷 45-55页

作者： Huiying Zhang Mengyang Tian Meiguang Jiang Jingyuan Yang Qi Xu Ying Zhang Minglu Ji Yuteng Yao Cancan Zhao Yuan Miao International Joint research Laboratory for global Change Ecology School of Life SciencesHenan UniversityKaifeng475004China Henan Dabieshan National Field Observation and research Station of Forest Ecosystem Xinyang Academy of Ecological ResearchXinyang464000China

The nitrogen(N)and phosphorus(P)addition promotes the abundance of soybean soil *** addition of nitrogen can alleviate the suppression of phosphorus on *** addition affects nematode abundance by ammonium nitrogen.

关键词： soil nematodes nitrogen addition phosphorus addition soil food web soybean

On-Chip Sub-Picometer Continuous Wavelength Fiber-Bragg-Grating Interrogator

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Photonic Sensors 2024年第1期14卷 73-84页

作者： Yuan ZHUANG Jun ZOU Jiqiang ZHANG Lu ZHANG Jiahe ZHANG Leixin MENG Qing YANG research Center for Humanoid Sensing Zhejiang LabHangzhou 311121China ZJU-Hangzhou global Scientific and Technological Innovation Center Hangzhou 310014China State Key Laboratory of Modern Optical Instrumentation College of Optical Science and EngineeringInternational Research Center for Advanced PhotonicsZhejiang UniversityHangzhou 310058China

Miniaturized fiber-Bragg-grating(FBG)interrogators are of interest for applications in the areas where weight and size controlling is important,e.g.,airplanes and aerospace or in-situ *** ultra-compact high-precision on-chip interrogator is proposed based on a tailored arrayed waveguide grating(AWG)on a silicon-on-insulator(SOI)*** on-chip interrogator enables continuous wavelength interrogation from 1544 nm to 1568 nm with the wavelength accuracy of less than 1 pm[the root-mean-square error(RMSE)is 0.73 pm]over the whole wavelength *** chip loss is less than 5 *** 1×16 AWG is optimized to achieve a large bandwidth and a low noise level at each channel,and the FBG reflection peaks can be detected by multiple output channels of the *** fabricated AWG is utilized to interrogate FBG sensors through the center of gravity(CoG)*** validation of an on-chip FBG interrogator that works with sub-picometer wavelength accuracy in a broad wavelength range shows large potential for applications in miniaturized fiber optic sensing systems.

关键词： Fiber optic sensing on-chip interrogator arrayed waveguide grating center of gravity

英文学术期刊审稿专家资源管理与维护——以global Health research and Policy为例

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出版与印刷 2024年第3期 22-28页

作者：王楠武汉大学公共卫生学院global Health research and Policy编辑部

探讨英文学术期刊审稿专家资源管理与维护,提高学术期刊同行评议的效能,加强期刊学术质量把控。文章基于在国际英文学术期刊global Health research and Policy的工作实践,根据期刊不同发展阶段的侧重点差异,辅以期刊动态指标数据分析,... 详细信息

探讨英文学术期刊审稿专家资源管理与维护,提高学术期刊同行评议的效能,加强期刊学术质量把控。文章基于在国际英文学术期刊global Health research and Policy的工作实践,根据期刊不同发展阶段的侧重点差异,辅以期刊动态指标数据分析,梳理并总结若干条顺应期刊发展规律的审稿专家资源拓展策略,旨在为我国英文学术期刊编辑与审稿专家建立稳定有效的合作互动提供参考。

关键词：同行评议审稿专家国际学术期刊英文期刊学术期刊编辑

Promoting higher-valent pediatric combination vaccines in China: challenges and recommendations for action

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Infectious Diseases of Poverty 2024年第1期13卷 74-84页

作者： Jiuling Li Shu Chen dwin Asturias Shenglan Tang Fuqiang Cui global Health research Center Duke Kunshan UniversityKunshanJiangsuChina ARC Centre of Excellence in Population Ageing research(CEPAR) Universityof New SouthWalesSydneyAustralia School of Risk and Actuarial Studies University of New South WalesSydneyAustralia Department of Pediatrics University of Colorado School of MedicineAuroraCOUSA Center for global Health Colorado School of Public HealthAuroraCOUSA Department of Epidemiology Colorado School of Public HealthAuroraCOUSA Duke global Health Institute Duke UniversityDurhamNCUSA SingHealth Duke-NUS global Health Institute Duke-NUSSingaporeSingapore Department of Laboratorial Science and Technology School of Public HealthPeking UniversityBeijingChina Vaccine research Center School of Public HealthPeking UniversityBeijingChina

Many countries have adopted higher-valent pediatric combination vaccines to simplify vaccination schedules and minimize health expenditures and social ***,China is conservative in the use of pediatric combina-tion *** reviewing and synthesizing quantitative and qualitative data,in this commentary we identify gaps and challenges to combination vaccine use and make recommendations for promoting use of higher-valent pediatric combination vaccines in *** are in four dimensions:(1)legislation and regulation,(2)immunization schedule design,(3)vaccine awareness and price,and(4)research and development *** optimize the use of combination vaccines to reduce vaccine-preventable disease burden,we make recommendations that address key challenges:(1)develop policies and regulations to strengthen enforcement of the Vaccine Administration Law and remove regulatory hurdles that hinder combination vaccine research and development,(2)establish an evi-dence-informed policy-making mechanism for combination vaccines,(3)resolve immunization schedule conflicts between monovalent and combination vaccines,and(4)implement effective interventions to increase vaccine awareness and reduce price.

关键词： Combination vaccine National immunization program Childhood immunization Vaccine-preventable disease