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Inhibitory gamma-aminobutyric acidergic neurons in the anterior cingulate cortex participate in the comorbidity of pain and emotion

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Neural Regeneration Research 2025年第10期20卷 2838-2854页

作者： Lu Guan Mengting Qiu Na Li Zhengxiang Zhou Ru Ye Liyan Zhong Yashuang Xu Junhui Ren Yi Liang Xiaomei Shao Jianqiao Fang Junfan Fang Junying Du Department of Neurobiology and Acupuncture Research Third School of Clinical MedicineZhejiang Chinese Medical UniversityHangzhouZhejiang ProvinceChina Key Laboratory for Research of Acupuncture Treatment and Transformation of Emotional Diseases Third School of Clinical MedicineZhejiang Chinese Medical UniversityHangzhouZhejiang ProvinceChina Fuchun Community Health Service Center of fuyang District HangzhouZhejiang ProvinceChina

Pain is often comorbid with emotional disorders such as anxiety and *** of the anterior cingulate cortex has been implicated in pain and pain-related negative emotions that arise from impairments in inhibitory gamma-aminobutyric acid *** review primarily aims to outline the main circuitry(including the input and output connectivity)of the anterior cingulate cortex and classification and functions of different gamma-aminobutyric acidergic neurons;it also describes the neurotransmitters/neuromodulators affecting these neurons,their intercommunication with other neurons,and their importance in mental comorbidities associated with chronic pain *** understanding on their role in pain-related mental comorbidities may facilitate the development of more effective treatments for these ***,the mechanisms that regulate gamma-aminobutyric acidergic systems remain *** is also unclear as to whether the mechanisms are presynaptic or *** exploration of the complexities of this system may reveal new pathways for research and drug development.

关键词： anterior cingulate cortex anxiety chronic pain circuit communication comorbidity depression gamma-aminobutyric acidergic neurons parvalbumin neurons synaptic transmission

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Double-sided subduction with contrasting polarities beneath the Pamir-Hindu Kush:Evidence from focal mechanism solutions and stress field inversion

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Geoscience Frontiers 2022年第4期13卷 98-113页

作者： Yu Yang Zuoxun Zeng Scott D.King Xiao Shuang School of Earth Sciences China University of Geosciences(Wuhan)Wuhan 430074China Huazhong Tectonomechanical Research Center China University of Geosciences(Wuhan)Wuhan 430074China Department of Geosciences Virginia TechBlacksburgVA 24061USA fuyang branch of hangzhou bureau of planning and natural resources Hangzhou 311499China

The Pamir-Hindu Kush region at the western end of the Himalayan-Tibet orogen is one of the most active regions on the globe with strong seismicity and deformation and provides a window to evaluate continental collision linked to two intra-continental subduction zones with different *** seismicity and seismic tomography data show a steep northward subducting slab beneath the Hindu Kush and southward subducting slab under the ***,we collect seismic catalogue with 3988 earthquake events to compute seismicity images and waveform data from 926 earthquake events to invert focal mechanism solutions and stress field with a view to characterize the subducting slabs under the Pamir-Hindu Kush *** results define two distinct seismic zones:a steep one beneath the Hindu Kush and a broad one beneath the *** and intermediate-depth earthquakes are mainly distributed in the Hindu Kush region which is controlled by thrust faulting,whereas the Pamir is dominated by strike-slip stress regime with shallow and intermediate-depth *** area where the maximum principal stress axis is vertical in the southern Pamir corresponds to the location of a highconductivity low-velocity region that contributes to the seismogenic processes in this *** interpret the two distinct seismic zones to represent a double-sided subduction system where the Hindu Kush zone represents the northward subduction of the Indian plate,and the Pamir zone shows southward subduction of the Eurasian plate.A transition fault is inferred in the region between the Hindu Kush and the Pamir which regulates the opposing directions of motion of the Indian and Eurasian plates.

关键词： Pamir-Hindu Kush Seismicity Stress field Double-sided subduction Low-velocity body

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Multi-Stage-Based Siamese Neural Network for Seal Image Recognition

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Computer Modeling in Engineering & Sciences 2025年第1期142卷 405-423页

作者： Jianfeng Lu Xiangye Huang Caijin Li Renlin Xin Shanqing Zhang Mahmoud Emam School of Computer Science and Technology Hangzhou Dianzi UniversityHangzhou310018China Shangyu Institute of Science and Engineering Hangzhou Dianzi UniversityShaoxing312300China Faculty of Artificial Intelligence Menoufia UniversityShebin El-Koom32511Egypt

Seal authentication is an important task for verifying the authenticity of stamped seals used in various domains to protect legal documents from tampering and *** seal inspection is commonly audited manually to ensure document ***,manual assessment of seal images is tedious and laborintensive due to human errors,inconsistent placement,and completeness of the *** image recognition systems are inadequate enough to identify seal types accurately,necessitating a neural network-based method for seal image ***,neural network-based classification algorithms,such as Residual Networks(ResNet)andVisualGeometryGroup with 16 layers(VGG16)yield suboptimal recognition rates on stamp ***,the fixed training data categories make handling new categories to be a challenging *** paper proposes amulti-stage seal recognition algorithmbased on Siamese network to overcome these ***,the seal image is pre-processed by applying an image rotation correction module based on Histogram of Oriented Gradients(HOG).Secondly,the similarity between input seal image pairs is measured by utilizing a similarity comparison module based on the Siamese ***,we compare the results with the pre-stored standard seal template images in the database to obtain the seal *** evaluate the performance of the proposed method,we further create a new seal image dataset that contains two subsets with 210,000 valid labeled pairs in *** proposed work has a practical significance in industries where automatic seal authentication is essential as in legal,financial,and governmental sectors,where automatic seal recognition can enhance document security and streamline validation ***,the experimental results show that the proposed multi-stage method for seal image recognition outperforms state-of-the-art methods on the two established datasets.

关键词： Seal recognition seal authentication document tampering siamese network spatial transformer network similarity comparison network

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Construction of Smart City Spatio-Temporal Information Cloud Platform in Weifang,China

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Journal of Donghua University(English Edition) 2019年第6期36卷 615-622页

作者： LIU Qianzhong LIU Xiaojing ZHAO Pingting Weifang natural resources and planning bureau Weifang 261041China

On the basis of the digital Weifang geospatial framework,Smart Weifang spatio-temporal information cloud platform(WFCP)integrated legal person information,population,place name and address data,macroeconomic data and so *** it also expanded the data contents,such as the indoor and outdoor data,the overground and underground data,panoramic data and real *** also introduced the contents of historical geographical information in different periods and real-time location information,address information of sensing equipment,real-time perception and interpreting *** has overcome the difficulties of real-time access of Internet of Things(IoT)perception,multi-node collaboration,64-bit support,cluster deployment and has the characteristics of spatio-temporal management,ondemand service,large data analysis and micro-service *** built spatio-temporal information big data center and spatio-temporal information cloud platform,realized the convergence and management of the distributed big data,deeply applied for land,transportation,environmental protection,police and subdistrict five areas,by supporting the integrated application of multi-source information and supporting intelligent deep *** the aspect of hardware environment construction,according to the top-level design and unified arrangement of Smart Weifang,the WFCP was migrated to Weifang cloud computing center,to achieve the on-demand computing resources and dynamic scheduling load-based computing resources,to support the generalizing load map application.

关键词： spatio-temporal information geospatial framework dataset Html5 technology NewMap spatio-temporal data engine spatio-temporal big data center

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A tasseled cap transformation for CBERS-02B CCD data

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Journal of Zhejiang University-Science B(Biomedicine & Biotechnology) 2011年第9期12卷 780-786页

作者： Li SHENG Jing-feng HUANG Xiao-lu TANG Institute of Agricultural Remote Sensing and Information Application Zhejiang UniversityHangzhou 310029China Key Laboratory of Agricultural Remote Sensing and Information System of Zhejiang Province Hangzhou 310029China Yuhang branch bureau of planning Hangzhou Urban Planning BureauHangzhou 311100China

The tasseled cap transformation of remote sensing data has been widely used in agriculture,forest,ecology,and *** this paper,tasseled cap transformation coefficients appropriate for data from a new sensor(China & Brazil Earth Resource Satellite(CBERS-02B)) are *** first three components after transformation captured 98% of the four-band variance,and represent the physical characteristics of brightness(coefficients:0.509,0.431,0.330,and 0.668),greenness(coefficients:0.494,0.318,0.324,and 0.741),and blueness(coefficients:0.581,0.070,0.811,and 0.003),*** hope these results will enhance the application of CBERS-02B charge-coupled device(CCD) data in the areas of agriculture,forest,ecology,and landscape.

关键词： Tasseled cap transformation CBERS-02B CCD Reflectance factor

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Molecular characterization and functional analysis of daf-8 in the pinewood nematode,Bursaphelenchus xylophilus

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Journal of Forestry Research 2022年第2期33卷 689-698页

作者： Jinghan Wang Huan Hong Rong Xie Jingjing Ji Kai Guo Liqun Bai Jia Tang Hongshi Yu Jianren Ye Jiafu Hu Nanjing Forestry University Nanjing 210037China Zhejiang Agricultural and Forestry University Hangzhou 311300China Yuhuan natural resources and planning bureau Taizhou 317600China School of BioSciences The University of MelbourneParkvilleVIC 3010Australia

Bursaphelenchus xylophilus,causal agent of pine wilt disease,causes extensive damage ***-gies are needed to inhibit population growth or block the spread of the invasive nematode to control pine wilt *** gene daf-8 plays crucial roles in larval develop-ment and dauer formation in Caenorhabditis elegans,but little is known about its orthologue in *** the present molecular characterization and functional analysis of daf-8 in ***(Bx-daf-8),RT-qPCR showed that the expression of Bx-daf-8 gradually increased during the embryonic stage,peaked in the second-stage juvenile(J2),then dramatically dropped in the J3,and remained at that low level for the rest of its ***-daf-8-transgenic *** was employed to mimic the spatiotemporal expression of Bx-daf-8,which was expressed close to the pharynx during early embryogenesis and weakly throughout the whole body during late *** was observed in head neurons and tail ganglions throughout all postembryonic *** embryos were severely abnormal,and hatching rate decreased sharply after Bx-daf-8 ***-16-1 and da-f16-2,downstream genes in the IIS pathway,also dropped sharply after Bx-daf-8 *** propose that TGFβmay crosstalk with the IIS pathway upstream of Bx-daf-16 and that daf-8 may act as a master regulator of daf-16 in ***,knockdown of Bx-daf-8 did not lead to constitutive developmental arrest at the dauer larval stage,indicating that dauer entry in *** might be controlled by several genes and is more complicated than in ***-daf-8 alone did not control the dauer entry in ***,but it was indispensable for embryogen-esis,providing a potential target for suppressing population growth of ***.

关键词： Daf-8 Expression pattern RNAi Embryogenesis Bursaphelenchus xylophilus

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Phospholipid fatty acid patterns of microbial communities in paddy soil under different fertilizer treatments

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Journal of Environmental Sciences 2007年第1期19卷 55-59页

作者： ZHANG Qi-chun WANG Guang-huo YAO Huai-ying Department of natural resources Zhejiang University Hangzhou 310029 China

The microbial communities under irrigated rice cropping with different fertilizer treatments, including control （CK）, PK, NK, NP, NPK fertilization, were investigated using phospholipid fatty acid （PLFA） profile method. The results of this study revealed that the fertilizer practice had an impact on the community structure of specific microbial groups. The principal components analysis （PCA） showed that proportion of the actinomycete PLFAs （10Me 18：0 and 10Me 16：0） were the lowest in the PK treatment and the highest in the NPK treatment, which means that soil nitrogen status affected the diversity of actinomycetes, whereas nitrogen cycling was related to the actinomycets. Under CK treatment, the ratio of Gram-positive to Gram-negative bacteria was lower compared with that in fertilizer addition treatments, indicating that fertilizer application stimulated Gram-positive bacterial population in paddy soil. The fatty acid 18：2to6,9, which is considered to be predominantly of fungal origin, was at low level in all the treatments. The ratio of cyl9：0 to 18：1 to7, which has been proposed as an indicator of stress conditions, decreased in PK treatment. Changes of soil microbial community under different fertilizer treatments of paddy soil were detected in this study; however, the causes that lead to changes in the microbial community still needs further study.

关键词： paddy soil fertilizers soil microorganisms community structure PLFA PCA

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Quantification of the effects of management factors on maize (Zea mays L.) and cotton(Gossypium hirsutum L.) residues decomposition rate

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Journal of Environmental Sciences 2002年第2期14卷 165-172页

作者： JONES Chilima, HUANG Chang yong, WU Ci fang (College of natural resources and Environment, Zhejiang University, hangzhou 310029, China. College of natural resources and Environment Zhejiang University Hangzhou 310029 China

Efforts to quantify management effects on decomposition rate of added substrates to the soil is important especially where such information is to be used for prediction in mathematical or simulation models. Using data from a short term (60 days) greenhouse simulation study, a procedure for quantifying effects of management on SOM and substrate decomposition is presented. Using microbial growth rate u (q), microbial efficiency in substrate utilization e (q), specific decomposition rates for added plant residues to two contrasting soils, red earth (Ferrasol) and black earth (Acrisol) were estimated. The treatments included straw addition + buried, (T1); straw addition + mineral N (T2); and straw addition + tillage, (T3). Sampling was done every 15 days. Straw decomposition rate was affected by external mineral N sources (Urea 46% N). Addition of an external N source significantly increased decomposition rates. The study could not, however, fully account for the effect of tillage on residues because of the limited effect of the tillage method due to the artificial barrier to mechanical interference supplied by the mesh bags. It is concluded that using few decomposer parameters, decomposition rates and consequently SOM trends in a soil system can be monitored and quantification of the influence of perturbations on decomposition rate of added substrates possible.

关键词： management factors residue decomposition rate maize cotton red soil black soil

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Ice sheet controls on fine-grained deposition at the southern Mendeleev Ridge since the penultimate interglacial

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Acta Oceanologica Sinica 2020年第9期39卷 86-95页

作者： Liming Ye Xiaoguo Yu Weiyan Zhang Rong Wang Key Laboratory of Submarine Geosciences Ministry of Natural ResourcesHangzhou 310012China Second Institute of Oceanography Ministry of Natural ResourcesHangzhou 310012China

Clay minerals deposited at the southern Mendeleev Ridge in the Arctic Ocean have a unique provenance,which can be used to reconstruct changes in the local sedimentary *** show that sediments in core ARC7-E23 record high-frequency changes in clay minerals since the penultimate *** clay minerals,grain size,and ice-rafted debris indicate the extent of the East Siberia Ice Sheet(ESIS).During the glacial periods of Marine Isotope Stage 2(MIS2)and MIS4,the southern Mendeleev Ridge was likely covered by an ESIS-extended ice shelf,blocking almost all sediment input from the Canadian Arctic and Laptev Sea,but allowing transport of fine-grained sediments from the East Siberian and Chukchi Sea *** ESIS retreat,the Beaufort Gyre and Transpolar Drift became the primary transport mechanism for the distally sourced *** conditions in MIS3 enhanced both the oceanic circulation and sediment transport.

关键词： Arctic Ocean Mendeleev Ridge East Siberian Ice Sheet clay minerals

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Geochemical characteristics of platinum-group elements in polymetallic nodules from the Northwest Pacific Ocean

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Acta Oceanologica Sinica 2020年第8期39卷 34-42页

作者： Zhongrong Qiu Yanhui Dong Weilin Ma Weiyan Zhang Kehong Yang Hongqiao Zhao Key Laboratory of Submarine Geosciences Ministry of Natural ResourcesHangzhou 310012China Second Institute of Oceanography Ministry of Natural ResourcesHangzhou 310012China

Polymetallic nodules and cobalt (Co)-rich crusts are enriched in platinum-group elements (PGEs),especially platinum (Pt) and may be important sinks of *** present,little information is available on PGEs in polymetallic nodules,and their geochemical characteristics and the causes of PGEs enrichment are *** PGEs of polymetallic nodules from abyssal basin in the Marcus-Wake Seamount area of the Northwest Pacific Ocean are reported and compared with the published PGEs data of polymetallic nodules and Co-rich crusts in the *** total PGEs (ΣPGE) content of polymetallic nodules in study area is 258×10^–9) in average,markedly higher than that of Clarion-Clipperton Zone (CCZ) nodules (ΣPGE=127×10^–9) and lower than that of Co-rich crusts in the Marcus-Wake Seamount (ΣPGE=653×10^–9),similar to that of Co-rich crusts in the South China Sea(ΣPGE=252×10^~–9).The CI chondrite-normalized PGEs patterns in different regions of polymetallic nodules and cobalt-rich crusts are highly consistent,with all being characterized by positive Pt and negative Pd anomalies These results,together with those of previous studies,indicate that PGEs in polymetallic nodules and Co-rich crusts are mainly derived directly from *** contents of polymetallic nodules from the study area are negatively correlated with water depth,and Pt/ΣPGE ratios in nodules there are also lower than those of the Corich crusts in the adjacent area,indicating that sedimentary water depth and oxygen fugacity of ambient seawater are the possible important controlling factors for Pt accumulation in crusts and nodules.

关键词： platinum-group elements polymetallic nodules Co-rich crusts Marcus-Wake Seamount

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