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Probing the interseismic locking state of the Xianshuihe fault based on a viscoelastic deformation model

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Science China Earth Sciences 2024年第1期67卷 134-145页

作者： Yage ZHU Faqi DIAO Fei CHEN Yuebing WANG Zhigang SHAO Rongjiang WANG Xiong XIONG Hubei Subsurface Multi-Scale imaging Key Laboratory School of Geophysics and GeomaticsChina University of GeosciencesWuhan 430074China China Earthquake Networks Center Beijing 100045China Institute of Earthquake Forecasting China Earthquake AdministrationBeijing 100036China

The interseismic locking state of tectonic faults is essential for regional seismic hazard ***,it is challenging to obtain this parameter reliably due to the weak deformation and complex model *** better probe the fault locking state,more reliable physical models and well-covered observations are *** we investigate the locking state of the Xianshuihe fault based on a new-developed viscoelastic deformation ***,we combine GPS velocities from 13 new near-field stations and existing stations in this region to improve the spatial *** to the theoretical predictions,our results indicate that the elastic model will clearly overestimate the fault locking depth and seismic moment accumulation rate,and the fault slip rate inferred from the elastic model is slightly lower than that from the viscoelastic *** on the locking distribution inferred from the viscoelastic model,we identify four potential asperities on the Xianshuihe *** importantly,we find a clear spatial correlation between the fault locking distribution and the rupture extent of historical earthquakes,which indicates that the fault locking state may control the rupture extent and thus the magnitude of *** addition,our results show that the 2022 M6.8 Luding earthquake only ruptured the south part of a potential asperity,and the accumulated energy in the northern unruptured area is equivalent to an Mw6.9 earthquake,where the seismic hazard deserves special attention.

关键词： Fault kinematics Viscoelastic relaxation effect GPS observations Seismic hazard The 2022 M6.8 Luding earthquake

Individualized brain mapping for navigated neuromodulation

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Chinese Medical Journal 2024年第5期137卷 508-523页

作者： Chaohong Gao Xia Wu Xinle Cheng Kristoffer Hougaard Madsen Congying Chu Zhengyi Yang Lingzhong Fan Sino–Danish College University of Chinese Academy of SciencesBeijing 100190China Brainnetome Center National Laboratory of Pattern RecognitionInstitute of AutomationChinese Academy of SciencesBeijing 100190China School of Artificial Intelligence University of Chinese Academy of SciencesBeijing 100190China Department of Applied Mathematics and Computer Science Technical University of DenmarkKongens Lyngby 2800Denmark Danish Research Centre for Magnetic Resonance Centre for Functional and Diagnostic Imaging and ResearchCopenhagen University Hospital Amager and HvidovreHvidovre 2650Denmark CAS Center for Excellence in Brain Science and Intelligence Technology Institute of AutomationChinese Academy of SciencesBeijing 100190China School of Health and Life Sciences University of Health and Rehabilitation SciencesQingdaoShandong 266000China

The brain is a complex organ that requires precise mapping to understand its structure and *** atlases provide a powerful tool for studying brain circuits,discovering biological markers for early diagnosis,and developing personalized treatments for neuropsychiatric *** techniques,such as transcranial magnetic stimulation and deep brain stimulation,have revolutionized clinical therapies for neuropsychiatric ***,the lack of fine-scale brain atlases limits the precision and effectiveness of these *** in neuroimaging and machine learning techniques have led to the emergence of stereotactic-assisted neurosurgery and navigation ***,the individual variability among patients and the diversity of brain diseases make it necessary to develop personalized *** article provides an overview of recent advances in individualized brain mapping and navigated neuromodulation and discusses the methodological profiles,advantages,disadvantages,and future trends of these *** article concludes by posing open questions about the future development of individualized brain mapping and navigated neuromodulation.

关键词： Brain atlas Individualization Navigated neuromodulation Multimodal magnetic resonance imaging Transcranial magnetic stimulation Deep brain stimulation

Model-driven CT reconstruction algorithm for nano-resolution x-ray phase contrast imaging

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Chinese Physics B 2024年第7期33卷 646-650页

作者：谭雨航蔡学宝杨杰成苏婷郑海荣梁栋朱佩平葛永帅 Research Center for Medical Artificial Intelligence Shenzhen Institute of Advanced TechnologyChinese Academy of SciencesShenzhen 518055China Institute of Electronic Paper Displays South China Academy of Advanced OptoelectronicsSouth China Normal UniversityGuangzhou 510006China Paul C Lauterbur Research Center for Biomedical imaging Shenzhen Institute of Advanced TechnologyChinese Academy of SciencesShenzhen 518055China Institute of High Energy Physics Chinese Academy of SciencesBeijing 100049China

The low-density imaging performance of a zone plate-based nano-resolution hard x-ray computed tomography(CT)system can be significantly improved by incorporating a grating-based Lau interferometer. Due to the diffraction, however,the acquired nano-resolution phase signal may suffer splitting problem, which impedes the direct reconstruction of phase contrast CT(nPCT) images. To overcome, a new model-driven nPCT image reconstruction algorithm is developed in this study. In it, the diffraction procedure is mathematically modeled into a matrix B, from which the projections without signal splitting can be generated invertedly. Furthermore, a penalized weighted least-square model with total variation(PWLSTV) is employed to denoise these projections, from which nPCT images with high accuracy are directly *** experiments demonstrate that this new algorithm is able to work with phase projections having any splitting distances. Moreover, results also reveal that nPCT images of higher signal-to-noise-ratio(SNR) could be reconstructed from projections having larger splitting distances. In summary, a novel model-driven nPCT image reconstruction algorithm with high accuracy and robustness is verified for the Lau interferometer-based hard x-ray nano-resolution phase contrast imaging.

关键词： splitting phase image reconstruction algorithm grating interferometer

FRET-based two-photon benzo[a]phenothiazinium photosensitizer for fluorescence imaging-guided photodynamic therapy

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Chinese Chemical Letters 2024年第7期35卷 325-328页

作者： Yiling Li Zekun Gao Xiuxiu Yue Minhuan Lan Xiuli Zheng Benhua Wang Shuang Zhao Xiangzhi Song College of Chemistry&Chemical Engineering Central South UniversityChangsha 410083China Key Laboratory of Photochemical Conversion and Optoelectronic Materials and City U-CAS Joint Laboratory of functional Materials and Devices Technical Institute of Physics and ChemistryChinese Academy of SciencesBeijing 100190China Department of Dermatology Xiangya HospitalCentral South UniversityChangsha 410083China

To overcome the conflict between the long-wavelength excitation and high singlet oxygen quantum yield of photosensitizers,we conjugated a two-photon fluorophore,tetrahydroquinoxaline coumarin(TQ),and an efficient photodynamic therapeutic agent,benzo[a]phenothiazinium(NBS-NH_(2)),through a hexamethylene linker to build a two-photon photosensitizer,*** TQ-NBS,TQ served as an energy donor and NBS-NH_(2) acted as an energy acceptor;and TQ-NBS was a F?rster resonance energy transfer(FRET)cassette with a 92.8%*** large two-photon absorption cross-section of TQ allowed photosensitizer TQ-NBS to work in a 900 nm two-photon excitation(TPE)mode,which greatly benefited the deep tissue penetration in PDT ***,the excellent phototoxicity and near-infrared fluorescence of NBS-NH2was kept in TQ-NBS under a TPE mode via a FRET *** TQ-NBS exhibited a high phototoxic efficacy in living cells and tumor-bearing mice.

关键词： Photodynamic therapy Two-photon excitation FRET-based photosensitizer Singlet oxygen Near-infrared fluorescence

Amide proton transfer:A new magnetic resonance imaging technology toward individualized assessment

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Chinese Medical Journal 2024年第13期137卷 1614-1616页

作者： Yiming Meng Jing Sun Guirong Zhang Tao Yu Department of Central Laboratory Cancer Hospital of Dalian University of TechnologyLiaoning Cancer Hospital&InstituteShenyangLiaoning 110042China Department of Biobank Cancer Hospital of Dalian University of TechnologyLiaoning Cancer Hospital&InstituteShenyangLiaoning 110042China Department of Medical imaging Cancer Hospital of Dalian University of TechnologyLiaoning Cancer Hospital&InstituteLiaoning 110042China

To the Editor:The amide proton transfer(APT)magnetic resonance imaging(MRI)is an emerging molecular imaging method for detecting mobile proteins/peptides and the potential of hydrogen(pH)with enhanced detection sensitivity compared to direct measurement without external magnetic resonance contrast agents[Figure 1].Such changes may be potential markers for tumor aggressiveness,treatment efficacy,and overall ***,the utilization of APT can assist medical professionals in devising treatment regimens tailored to the individual needs of cancer patients,resulting in improved therapeutic outcomes.

关键词： Figure resonance transfer

Life Time Attributable Cancer Risk Estimated Using Scanner Reported Dose Length Product during Chest Computed Tomography imaging in Young Children

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Open Journal of Radiology 2024年第2期14卷 74-82页

作者： Mousa Bakkari Khaled Soliman Abdullah Alrushoud Marwan Fahad Alosaimi Hanaa Alsheikh Abdelwahed Alhejaili Medical Physics Department Prince Sultan Military Medical City Riyadh Saudi Arabia Radiogiadnostic and Medical imaging Department Prince Sultan Military Medical City Riyadh Saudi Arabia

This study aims to estimate the lifetime attributable cancer risk (LAR) for pediatric chest computed tomography (CT) examinations in five age groups using recently published age and region-specific conversion coefficients multiplying the widely available scanner registered dose length products (DLP) displayed on the CT console and hence calculating the Effective Dose (ED). The ED is then multiplied by the International Commission on Radiological Protection (ICRP) published risk factor for LAR. The obtained LAR values are compared with the international literature. Factors that may affect the LAR value are reported and discussed. The study included one hundred twenty five chest CT examinations for both males and females aged from less than one year to fifteen years. The patients reported data are from one single medical institution and using two CT scanners from June 2022 to December 2023. The results of this study may serve as benchmark for institutional radiation dose reference levels and risk estimation.

关键词： Cancer Risk LAR Chest CT Pediatric Radiology Radiation Dose DLP

A multi-mechanistic approach to the oil recovery study of a family of amphiphilic polysaccharides

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Petroleum Research 2024年第2期9卷 238-249页

作者： Funsho Afolabi Syed MMahmood Lunech Mario Nur Asyraf Md Akhir Bennett Tackie-Otoo Hamid Sharifigaliuk Center of Research in Enhanced Oil Recovery Universiti Teknologi PETRONASSeri IskandarMalaysia Center for Subsurface imaging Universiti Teknologi PETRONASSeri IskandarMalaysia Research Institute of Petroleum Industry(RIPI) TehranIran

Chemical enhanced oil recovery(cEOR)remains one of the most potent tertiary recovery ***,it is expensive and rarely environmentally ***-based amphiphilic polymers have been suggested as an alternative to eradicating the challenges of conventional cEOR because of cost-effectiveness,and ***,few in-depth studies exist in the literature to investigate the prospects of these materials.A new family of amphiphilic polysaccharides was synthesized by hydrophobic modification of cellulose sulphate,and the EOR functionalities were *** novel biopolymers exhibited the ability to alter rock wetting *** terms of recovery,one of the variants of the synthesized bio amphiphilic polymer(D-I)was able to reduce residual oil saturation to 12%at harsh conditions of 60,000 ppm salinity at 75℃.Micromodel visual analysis revealed that the performance of the novel materials was due to the combination of mobility control,IFT lowering and emulsification,wettability alteration,and *** a performance commensurate to that of a commercial hydrophobically modified polymer,it can be said that the novel amphiphilic polysaccharides can stand as a viable cEOR agent for oilfield applications.

关键词： Bio-based polymers Amphiphilic polysaccharides EOR Cellulose sulphate Environmental sustainability

Magnetic resonance imaging scanning susceptibility weighted imaging sequences in the diagnosis and prognostic evaluation of neonatal hypoxic-ischemic encephalopathy

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World Journal of Clinical Cases 2024年第17期12卷 3012-3018页

作者： Hui Zhao Hai-Tao Wang Department of Neonatology Hanzhong People's HospitalHanzhong 723000Shaanxi ProvinceChina Department of Medical imaging Hanzhong People's HospitalHanzhong 723000Shaanxi ProvinceChina

BACKGROUND Magnetic resonance imaging(MRI)scanning with susceptibility weighted imaging(SWI)sequences plays a significant role in the diagnosis and prognostic evaluation of neonatal hypoxic-ischemic encephalopathy(HIE).AIM To observe the role of MRI multi-parameter quantitative indexes in the diagnosis of neonatal *** The imaging data from 23 cases of neonatal HIE admitted to the imaging Department of Ganyu District People's Hospital of Lianyungang City and 23 neonates without HIE admitted during the same period were analyzed retrospectively from August,2021 to December,*** results of clinical judgment were compared with the results of computed tomography(CT)and MRI *** The degree of cerebral edema(more than moderate),the number of damaged brain regions(>2),the number of cerebral hemorrhages(>2),and the percentage of small venous dilatation detected were higher in MRI than in CT examination,and the differences were statistically significant(Pimaging and SWI had higher sensitivity and accuracy than CT diagnosis,and the difference was statistically significant(P0.05).CONCLUSION The use of MRI multi-parameter quantitative indexes can accurately diagnose and evaluate neonatal HIE.

关键词： Hypoxic-ischemic encephalopathy Neonate Diagnostic efficacy

Ultrasound of the Rotator Cuff in Non-Fractured Shoulder Trauma: 30 Cases at the Yalgado Ouedraogo University Hospital of Ouagadougou (Burkina Faso)

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Open Journal of Medical imaging 2024年第2期14卷 64-71页

作者： Milckisédek Judicaël Marouruana Some Aïda Ida Tankoano Pakisba Ali Ouedraogo Ladouon Sylvie Simboro Bassirou Kindo Siaka Ben Aziz Dao Rabiou Cisse Department of Medical imaging The Ouahigouya Regional University Hospital University of Ouahigouya Ouahigouya Burkina Faso Department of Medical imaging Souro Sanou University Hospital Nazi Boni University Bobo Dioulasso Burkina Faso Department of Medical imaging Workers Health Office Ouagadougou Burkina Faso Department of Medical imaging Yalgado Oudraogo University Hospital Joseph Ki Zerbo University Ouagadougou Burkina Faso

Introduction: Ultrasound is the imaging technique of choice for the study of rotator cuff lesions. However, in the case of shoulder trauma, it is rarely requested in our context. This study aimed to show ultrasound lesions of the rotator cuff in cases of non-fracture shoulder trauma at the CHUYO in Ouagadougou. Methodology: This was a prospective descriptive cross-sectional study running from August 1 to November 30, 2017, in the medical imaging department of CHUYO. The study population consisted of patients received in the department for ultrasound in the context of non-fracture shoulder trauma. Results: We collected 20 cases (66.67%) of rotator cuff lesions out of 30 non-fracture shoulder injuries. The mean age of the patients was 27.6 years. Road traffic accidents accounted for 60% of injuries, sports accidents for 30%, and domestic accidents for 10%. Ultrasound lesions were mainly tendon ruptures (36.67%) and tendinitis (23.33%). Ruptures were non-transfixing in 90.90% of cases. The supraspinatus was the most affected (81.81%). Conclusion: Ultrasound can help diagnose rotator cuff injuries, particularly in non-fractured shoulder trauma.

关键词： Traumatic Shoulder Rotator Cuff Ultrasound