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Myocardial metastasis from ZEB1-and TWIST-positive spindle cell carcinoma of the esophagus:A case report

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World Journal of Gastroenterology 2024年第11期30卷 1636-1643页

作者： Yoshihiro Shibata Hirofumi Ohmura Kazuki Komatsu Kosuke Sagara Atsuji Matsuyama Ryuji Nakano Eishi Baba Department of Medical Oncology Fukuoka Wajiro HospitalFukuoka 811-0213Japan Department of Oncology and Social Medicine Kyushu University Graduate School of Medical SciencesFukuoka 812-8582Japan Department of Pathology and Oncology University of Occupational and Environmental HealthKitakyushu 807-8555Japan Department of Diagnostic Pathology Fukuoka Wajiro HospitalFukuoka 811-0213Japan

BACKGROUND Metastatic cardiac tumors are known to occur more frequently than primary cardiac tumors,however,they often remain asymptomatic and are commonly dis-covered on *** tumors with a relatively high frequency of cardiac metastasis include mesothelioma,melanoma,lung cancer,and breast cancer,whereas reports of esophageal cancer with cardiac metastasis are *** SUMMARY The case of a 60-year-old man who complained of dysphagia is *** gastrointestinal endoscopy showed a submucosal tumor-like elevated lesion in the esophagus causing ***-enhanced computed tomography showed left atrial compression due to the esophageal tumor,multiple liver and lung metastases,and a left pleural *** examination of a biopsy speci-men from the esophageal tumor showed spindle-shaped cells,raising suspicion of esophageal *** disease progressed rapidly,and systemic chemotherapy was deemed necessary,however,due to his poor general condition,adminis-tration of cytotoxic agents was considered *** his high Combined Positive Score,nivolumab was administered,however,the patient soon died from the *** autopsy confirmed spindle cell carcinoma(SCC)of the esophagus and cardiac metastasis with similar histological *** stem cell markers,ZEB1 and TWIST,were positive in both the primary tumor and the cardiac *** To the best of our knowledge,there have been no prior reports of cardiac metastasis of esophageal *** case highlights our experience with a patient with esophageal SCC who progressed rapidly and died from the disease,with the autopsy examination showing cardiac metastasis.

关键词： Spindle cell carcinoma Esophagus Myocardial metastasis Epithelial-mesenchymal transition Case report

Experimental study on boundary lubricity of superficial area of articular cartilage and synovial fluid

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Friction 2024年第5期12卷 981-996页

作者： Wenxiao LI Takehiro MORITA Yoshinori SAWAE Departure of Mechanical Engineering Kyushu UniversityFukuoka8190395Japan International Institute for Carton-Neutral Energy Research Kyushu UniversityFukuoka8190395Japan Advanced Research Center for Biomechanics Kyushu UniversityFukuoka8190395Japan

The boundary lubrication mechanism at the articulating surface of natural synovial joints has been the subject of much discussion in *** this study,to elucidate the lubricating function of the superficial area of articular cartilage and synovial fluid(SF),cartilage specimens were processed with four different treatments:gentle and severe washing with detergent,incubation in NaCl solution,and trypsin digestion to selectively remove certain constituents from the cartilage ***,the frictional characteristics were examined in phosphate-buffered saline(PBS)and SF against *** reciprocating sliding tests with a spherical glass probe and square articular cartilage specimens were performed at low contact loads in the mN range to extract the frictional behavior in the superficial area of the cartilage ***,the cartilage surface was observed to confirm the effects of treatments on the morphology of the cartilage surface using a fluorescence microscope and water-immersion *** coefficient of friction(COF)of the prepared cartilage specimens was varied from 0.05 to over 0.3 in ***,a certain group of cartilage specimens exhibited a low COF of less than 0.1 with limited *** the low COF group of specimens,all four treatments increased the COF in PBS to different extents,and fluorescence microscopy revealed that the integrity of the cartilage surface was deteriorated by *** means that the intact cartilage surface had lubricating constituents to maintain low friction,and the removal of such constituents resulted in the loss of the intrinsic boundary lubricity of the cartilage *** variation in the COF of the cartilage specimens was suppressed in SF because it had a clear boundary lubrication effect on the cartilage *** lubricating effect of SF could be confirmed even after degenerative treatment.

关键词： articular cartilage synovial fluid the uppermost superficial layer boundary lubrication

Hybrid Strategy of Partitioned and Monolithic Methods for Solving Strongly Coupled Analysis of Inverse and Direct Piezoelectric and Circuit Coupling

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Computer Modeling in Engineering & Sciences 2024年第8期140卷 1371-1386页

作者： Daisuke Ishihara Syunnosuke Nozaki Tomoya Niho Naoto Takayama Department of Intelligent and Control Systems Kyushu Institute of TechnologyFukuokaJapan

The inverse and direct piezoelectric and circuit coupling are widely observed in advanced electro-mechanical systems such as piezoelectric energy *** strongly coupled analysis methods based on direct numerical modeling for this phenomenon can be classified into partitioned or monolithic *** formulation has its advantages and disadvantages,and the choice depends on the characteristics of each coupled *** study proposes a new option:a coupled analysis strategy that combines the best features of the existing formulations,namely,the hybrid partitioned-monolithic *** analysis of inverse piezoelectricity and the monolithic analysis of direct piezoelectric and circuit interaction are strongly coupled using a partitioned iterative hierarchical *** a typical benchmark problem of a piezoelectric energy harvester,this research compares the results from the proposed method to those from the conventional strongly coupled partitioned iterative method,discussing the accuracy,stability,and computational *** proposed hybrid concept is effective for coupled multi-physics problems,including various coupling conditions.

关键词： Structure-piezoelectric-circuit interaction energy harvesting partitioned method monolithic method hybrid method

Autohydrolysis treatment of bamboo and potassium oxalate(K_(2)C_(2)O_(4))activation of bamboo product for CO_(2) capture utilization

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Frontiers of Chemical Science and Engineering 2024年第4期18卷 63-72页

作者： Dang Duc Viet Doan Thi Thao Khuong Duy Anh Toshiki Tsubota Department of Materials Science Faculty of EngineeringKyushu Institute of TechnologyFukuoka 804-8550Japan Vietnamese Academy of Forest Sciences Hanoi 10000Vietnam Collaborative Research Centre for Green Materials on Environmental Technology Kyushu Institute of TechnologyFukuoka 808-0196Japan

Typically,the hydroxide agents,such as sodium hydroxide and potassium hydroxide,which have corrosive properties,are used in the carbon activation *** this study,potassium oxalate(K_(2)C_(2)O_(4)),a less toxic and non-corrosive activating reagent,was used to synthesize activated carbon from the solid residue after autohydrolysis *** effect of the autohydrolysis treatment and the ratio of the K_(2)C_(2)O_(4)/solid residue are presented in this ***,the comparison between the activated carbon from bamboo and biochar from the solid residue are also *** resulting activated carbon from the solid residue exhibited a high surface area of up to 1432 m^(2)·g^(-1) and a total pore volume of up to 0.88 cm^(3)·g^(-1).The autohydrolysis treatment enhanced the microporosity properties compared to those without pretreatment of the activated *** microporosity of the activated carbon from the solid residue was dominated by the pore width at 0.7 nm,which is excellent for CO_(2) *** 25℃ and 1.013×10^(5) Pa,the CO_(2) captured reached up to 4.1 mmol·g^(-1).On the other hand,the ratio between K_(2)C_(2)O_(4) and the solid residue has not played a critical role in determining the porosity *** ratio of the K_(2)C_(2)O_(4)/solid residue of 2 could help the carbon material reach a highly microporous textural property that produces a high carbon capture *** finding proved the benefit of using the solid residue from the autohydrolysis treatment as a precursor material and offering a more friendly and sustainable activation carbon process.

关键词： activated carbon bamboo biochar CO_(2)capture potassium oxalate

How are multiple satellites seen from the ground? Relative apparent motion and formation stabilization

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Astrodynamics 2024年第1期8卷 121-134页

作者： Kenta Nakajima Yasuhiro Yoshimura Hongru Chen Toshiya Hanada Department of Aeronautics and Astronautics Kyushu University744 Motooka Nishi-kuFukuoka819-0395Japan

This paper answers how multiple satellites are seen from the ground. This question is inspired by space-advertising, a public exhibition in the night sky using a dot matrix of satellites that are bright enough to be seen by the naked eye. Thus, it is important for space advertisement that the specific dot matrix is seen. Moreover, the stability of the dot matrix during a visible span is very valuable. To stabilize the dot matrix, this study formulates an apparent position of a dot from a representative dot seen from the ground. The formulation, linear functions of a set of relative orbital elements, reveals the appearance of the dot matrix. The proposed relative variable in the formulation drives the instability of the dot matrix, thereby revealing an initial stable configuration of deputies from a chief. The arbitrary dot matrix designed using the configuration is stable even at low elevations without orbital control during the visible span.

关键词： formation flying relative motion stabilization astrodynamics multi-apparent motions space advertisement

Classification of complete 3-dimensional self-shrinkers in the Euclidean space R^(4)

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Science China Mathematics 2024年第4期67卷 873-882页

作者： Qing-Ming Cheng Zhi Li Guoxin Wei Department of Applied Mathematics Faculty of ScienceFukuoka UniversityFukuoka 814-0180Japan College of Mathematics and Information Science Henan Normal UniversityXinxiang 453007China School of Mathematical Sciences South China Normal UniversityGuangzhou 510631China

In this paper,we completely classify 3-dimensional complete self-shrinkers with the constant norm S of the second fundamental form and the constant f3in the Euclidean space R^(4),where hij’s are components of the sec... 详细信息

关键词： mean curvature ow self-shrinker the generalized maximum principle

Epigenetic memory of drug exposure history controls neural stem cell quiescence in the adult brain

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Neural Regeneration Research 2024年第4期19卷 711-712页

作者： Masakazu Iwamoto Taito Matsuda Department of Stem Cell Biology and Medicine Graduate School of Medical SciencesKyushu UniversityFukuokaJapan

Neural stem cells(NSCs)are the source of all neurons and glial cells(astrocytes and oligodendrocytes)in the central nervous *** adult mammalian brain retains NSCs in the subgranular zone of the dentate gyrus in the hippocampus and ventricular subventricular zone lining the lateral ventricle(Olpe and Jessberger,2022).Adult NSCs in rodents are preserved throughout life and continuously produce new neurons that integrate into the pre-existing neuronal network.

关键词： neural integrate continuously

Optimizing piezoelectric performance of complex perovskite through increasing diversity of B-site cations

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Journal of Materials Science & Technology 2024年第3期170卷 78-86页

作者： Mengdi Cheng Dongyan Zhang Yangxi Yan Zhimin Li Pangpang Wang Ri-ichi Murakami School of Advanced Materials and Nanotechnology Xidian UniversityXi’an 710126China Nanomaterials Group Institute of SystemInformation Technologies and Nanotechnologies(ISIT)Fukuoka Industry-Academia Symphonicity(FiaS)4-1 KyudaishinmachiNishi-kuFukuoka 819-0388Japan School of Mechanical Engineering Chengdu UniversityChengdu 610106China

Piezoelectric materials with unique properties are hugely appealing for high sensitivity sensors and ultrasonic ***,Pb(Ni_(1/3)Nb_(2/3))O_(3)-Pb(Yb_(1/2)Nb_(1/2))O_(3)-PbTiO_(3)piezoelectric system was designed and investigated in *** optimized piezoelectric response(d_(33)=826 pC/N,d_(33)∗=1017 pm/V)together with good temperature stability and negligible performance degradation up to 10^(6) cycles was achieved in 0.58PNN-0.10PYN-0.32PT *** analysis revealed the amplification of intrinsic and extrinsic contributions in MPB region due to more spontaneous polarization orientations and an increase in chemical disorder of system after the introduction of *** origin of high piezoelectric response was investigated through the combination of scanning electron microscopy and piezoresponse force *** diversity of B-site cations was shown to enhance local structural heterogeneity,weaken long-range ferroelectric ordered domains,and lower free energy barrier via the formation of nanodomain configuration that promoted polarization rotation,thereby improving piezoelectric properties of the ***,it is suggested that increasing the diversity of B-site cations is an effective strategy for achieving outstanding piezoelectric performance.

关键词： PNN-PYN-PT ceramics Piezoelectricity enhancement Relaxation behavior Domain structure

Strategy for suppressing abnormal grain growth of ZK60 Mg alloy during solution by pre-compression:A quasi-in-situ study

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Journal of Materials Science & Technology 2024年第4期171卷 115-128页

作者： Zhenxu Wang Liang Chen Jianwei Tang Cunsheng Zhang Guoqun Zhao Key Laboratory for Liquid-Solid Structural Evolution and Processing of Materials(Ministry of Education) Shandong UniversityJinanShandong 250061China Department of Mechanical Engineering Kyushu UniversityFukuoka 819-0395Japan

Abnormal grain growth(AGG)easily takes place in Mg alloys during high-temperature solutions,result-ing in deterioration of mechanical ***,the compression prior to solution(pre-compression)was conducted to suppress AGG,and the microstructure evolution as well as suppressing mechanisms was investigated based on quasi-in-situ *** compression along the transverse direction,//ED grains preferentially nucleated and rapidly grew up,and the initial//ED texture was *** grain growth modes of heat-induced and strain-induced grain boundary migrations were *** former was attributed to the high interfacial energy of grain boundaries with large *** latter consumed the adjacent grains with high storage energy,forming abnormal grains with irregular *** compression with a reduction>6%could obviously suppress *** suppressing effects were mainly attributed to weakening the size advantage of//ED grains,increasing nucleation,reducing grain boundary character distribution,and redistributing storage energy *** 12%compression along the transverse direction,30°misorientation of//ED grains and high energy grain boundaries were ***{10-12}tensile twins and{10-15}high index twins induced by com-pression increased the nucleation of static ***,compression introduces high-density dislocations,which also contributed to suppressing AGG behavior during solution.

关键词： Quasi-in-situ analysis Mg alloy Abnormal grain growth Compression Microstructure