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Editorial:special topic on biomaterials and bioinspired materials

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Science China Materials 2024年

作者： Mingjie Liu Xu Hou Dan Wang key laboratory of Bio-Inspired Smart Interfacial Science and Technology of Ministry of Education School of Chemistry Beihang University International research Institute for Multidisciplinary Science Beihang University State key laboratory of Physical Chemistry of Solid Surfaces College of Chemistry and Chemical Engineering Xiamen University research Institute for Biomimetics and Soft Matter Fujian Provincial Key Laboratory for Soft Functional Materials Research College of Physical Science and Technology Xiamen University State key laboratory of Biochemical Engineering Key Laboratory of Biopharmaceutical Preparation and Delivery Institute of Process Engineering Chinese Academy of Sciences University of Chinese Academy of Sciences

Biomaterials have been persistently focused owing to their intricate design and efficient operation. In order to satisfy the demands of life and medical sciences, large amounts of biomaterials capable of interacting with living systems have been created, thereby achieving the diagnosis, treatment or replacement of cells, tissues, and organs. After continuous evolution for billions of years, living organisms have eventually developed sophisticated multi-scale structures with diverse biological functions to adapt to the external environment.

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Clovibactin:一种对病原体展现致死效应且低耐药性的革命性抗生素

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Science Bulletin 2024年第5期69卷 570-573页

作者：李翔吴敏帅建伟 Department of Physics and Fujian Provincial Key Lab for Soft Functional Materials ResearchXiamen UniversityXiamen 361005China Joint research Centre on Medicine The Affiliated Xiangshan Hospital of Wenzhou Medical UniversityNingbo 315700China Wenzhou Institute University of Chinese Academy of SciencesWenzhou 325000China Oujiang laboratory(Zhejiang Lab for Regenerative Medicine Vision and Brain Health)Wenzhou 325001China

The decades spanning from the 1940s to the 1960s are renowned as the heyday of antibiotic discovery.It was during this era that game-changing antibiotics such as streptomycin,vancomycin,and tetracycline were unearthed,fundamentally reshaping the landscape of modern medicine.However,antibiotic discovery faces alarming challenges and traditional screening has not yielded new drugs in many decades.The crisis of antimicrobial resistance(AMR)emerges as a consequence of the unintended disruption of the antibiotic discovery pipeline and the subsequent uncontrolled proliferation of resistant pathogens[1].According to the World health Organization(WHO),in 2019,approximately1.2 million people worldwide died of bacterial infections exacerbated by AMR,surpassing the number of deaths caused by HIV/AIDS.If this trend continues,by 2050,AMR could potentially result in over 10 million deaths,surpassing the mortality rate attributed to cancer.Thus,we are in dire need of new antibiotics to counter the rising resistance of bacteria to most currently employed clinical antibiotics.

关键词： passing landscape attributed

Oral administration of Bacillus coagulans TQ-35 alleviates allergic responses in OVA-sensitive BALB/c mice

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Food Science and Human Wellness 2024年第3期13卷 1246-1257页

作者： Yifan Wang Shanjun Chen Chong Wang Yi Zhang Hongliang Zeng Linglin Fu Yanbo Wang Food Safety key laboratory of Zhejiang Province School of Food Science and BiotechnologyZhejiang Gongshang UniversityHangzhou 310018China College of Food Science Fujian Agriculture and Forestry UniversityFuzhou 350002China School of Food and health Beijing Technology and Business UniversityBeijing 100048China

Bacillus coagulans has been extensively studied so far,but there has been a lack of research on its usage in allergy.In this study,we designed to assess the effect of different concentrations of B.coagulans on food allergy in a BALB/c mouse model of ovalbumin(OVA)-induced food allergy and its effect on gut microbes.The assessment of symptoms,specific immunoglobulin E(IgE),T-cell differentiation,and related gene expression levels in sensitized mice by assay indicated that high doses of oral B.coagulans could alleviate allergic symptoms.Treatment with B.coagulans,in the high-dose group,significantly reduced IgE and IgG1 levels and modulated the balance of T helper type 1 cell(Th1)and Th2 and the expression of relevant genes in the spleen.16S rRNA analysis showed that probiotics improved the structure of the microbiota,in particular by boosting the percentage of Clostridia,Bacteroides vulgatus and Enterococcus faecium,and by increasing the abundance of microbial species,thereby modulating the immune system.Therefore,this study can provide insights into the practical application of B.coagulans doses to alleviate OVA allergy.

关键词： Bacillus coagulans TQ-35 Food allergy Ovalbumin(OVA) Gut microbiota

Nontrivial Topological Phases in Ternary Borides M_(2)XB_(2)(M=W,Mo;X=Co,Ni)

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Chinese Physics Letters 2024年第3期41卷 131-139页

作者：袁丹文岳长明胡岳芳张薇 fujian provincial key laboratory of Quantum Manipulation and New Energy Materials College of Physics and EnergyFujian Normal UniversityFuzhou 350117China fujian provincial Collaborative Innovation Center for Advanced High-Field Superconducting Materials and Engineering Fuzhou 350117China Academy of Carbon Neutrality of fujian Normal University Fuzhou 350007China Department of Physics Southern University of Science and TechnologyShenzhen 518055China

The nontrivial band topologies protected by certain symmetries have attracted significant interest in condensed matter physics.The discoveries of nontrivial topological phases in real materials provide a series of arc... 详细信息

关键词： nontrivial topological Ternary

Improved performance of LiMn_(0.8)Fe_(0.2)PO_(4) by addition of fluoroethylene carbonate electrolyte additive

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Chinese Chemical Letters 2024年第6期35卷 229-233页

作者： Guihuang Fang Wei Chen Hongwei Yang Haisheng Fang Chuang Yu Maoxiang Wu Faculty of Metallurgy and Energy Engineering Kunming University of Science and TechnologyKunming 650093China key laboratory of Optoelectronic Materials Chemistry and Physics Fujian Institute of Research on the Structure of MatterChinese Academy of SciencesFuzhou 350002China State key laboratory of Advanced Electromagnetic Engineering and Technology School of Electrical and Electronic EngineeringHuazhong University of Science and TechnologyWuhan 430074China

The addition of electrolyte additives is an effective strategy for tuning the property of the electrolyte to engineer the electrode/electrolyte interface,and there exist obvious discrepancies regarding the effect of fluoroethylene carbonate(FEC)as an electrolyte additive on the performance of cathodes.Herein FEC is introduced into the electrolyte of the LiMn_(0.8)Fe_(0.2)PO_(4)/Li cell and its effect on the properties of the LiMn_(0.8)Fe_(0.2)PO_(4) is investigated.It is found that the addition of FEC in the electrolyte has a positive effect on the performance of the LiMn_(0.8)Fe_(0.2)PO_(4) cathode,which can be attributed to the reduced products generated by the interfacial side-reactions on the LiMn_(0.8)Fe_(0.2)PO_(4) cathode surface and the decreased metal dissolution in the FEC-containing electrolyte,thanks to the higher oxidation resistance of FEC and the easier and stronger binding of FEC and PF_6^(-).

关键词： Lithium-ion batteries LiMn_(0.8)Fe_(0.2)PO_(4) Cathode Electrolyte additives Fluoroethylene carbonate

Dear-DIA^(XMBD): Deep Autoencoder Enables Deconvolution of Data-Independent Acquisition Proteomics

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research 2024年第1期6卷 707-720页

作者： Qingzu He Chuan-Qi Zhong Xiang Li Huan Guo Yiming Li Mingxuan Gao Rongshan Yu Xianming Liu Fangfei Zhang Donghui Guo Fangfu Ye Tiannan Guo Jianwei Shuai Jiahuai Han Department of Physics and Fujian Provincial Key Laboratory for Soft Functional Materials ResearchXiamen UniversityXiamen 361005China Oujiang laboratory(Zhejiang Lab for Regenerative Medicine Vision and Brain Health)and Wenzhou InstituteUniversity of Chinese Academy of SciencesWenzhouZhejiang 325001China School of Life Sciences Xiamen UniversityXiamen 361102China State key laboratory of Cellular Stress Biology Innovation Center for Cell Signaling NetworkXiamen 361102China Department of Computer Science Xiamen UniversityXiamen 361005China National Institute for Data Science in health and Medicine School of MedicineXiamen UniversityXiamen 361102China Bruker(Beijing)Scientific Technology Co.Ltd. BeijingChina Westlake laboratory of Life Sciences and Biomedicine Key Laboratory of Structural Biology of Zhejiang ProvinceSchool of Life SciencesWestlake University18 Shilongshan RoadHangzhou 310024China Institute of Basic Medical Sciences Westlake Institute for Advanced Study18 Shilongshan RoadHangzhou 310024China Westlake Omics Ltd. Yunmeng Road 1HangzhouChina Department of Electronic Engineering Xiamen UniversityXiamen 361005China

Data-independent acquisition(DIA)technology for protein identification from mass spectrometry and related algorithms is developing rapidly.The spectrum-centric analysis of DIA data without the use of spectra library from data-dependent acquisition data represents a promising direction.In this paper,we proposed an untargeted analysis method,Dear-DIA^(XMBD),for direct analysis of DIA data.Dear-DIA^(XMBD) first integrates the deep variational autoencoder and triplet loss to learn the representations of the extracted fragment ion chromatograms,then uses the k-means clustering algorithm to aggregate fragments with similar representations into the same classes,and finally establishes the inverted index tables to determine the precursors of fragment clusters between precursors and peptides and between fragments and peptides.We show that Dear-DIA^(XMBD) performs superiorly with the highly complicated DIA data of different species obtained by different instrument platforms.

关键词： Deep Auto Independent

Emerging WS_(2)/WSe_(2)@graphene nanocomposites: synthesis and electrochemical energy storage applications

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Rare Metals 2024年第1期43卷 1-19页

作者： Yu-Meng Gao Yong Liu Kai-Jia Feng Jun-Qing Ma Ying-Jie Miao Bin-Rui Xu Kun-Ming Pan Osaka Akiyoshi Guang-Xin Wang Ke-Ke Zhang Qiao-Bao Zhang National Joint Engineering research Center for Abrasion Control and Molding of Metal Materials Henan Key Laboratory of Non-Ferrous Materials Science and Processing TechnologySchool of Materials Science and EngineeringHenan University of Science and TechnologyLuoyang 471023China provincial and Ministerial Co-Construction of Collaborative School of Electrical Engineering Henan University of Science and TechnologyLuoyang 471023China Biomaterials laboratory Faculty of EngineeringOkayama UniversityTsushima-NakeOkayama-Shi 700-8530Japan Department of Materials Science and Engineering College of MaterialsXiamen UniversityXiamen 361005China fujian key laboratory of Surface and Interface Engineering for High Performance Materials Xiamen UniversityXiamen 361005China

In recent years, tungsten disulfide(WS_(2)) and tungsten selenide(WSe_(2)) have emerged as favorable electrode materials because of their high theoretical capacity, large interlayer spacing, and high chemical activity;nevertheless, they have relatively low electronic conductivity and undergo large volume expansion during cycling, which greatly hinder them in practical applications. These drawbacks are addressed by combining a superior type of carbon material, graphene, with WS_(2) and WSe_(2) to form a WS_(2)/WSe_(2)@graphene nanocomposites.These materials have received considerable attention in electro-chemical energy storage applications such as lithium-ion batteries(LIBs), sodium-ion batteries(SIBs),and supercapacitors. Considering the rapidly growing research enthusiasm on this topic over the past several years, here the recent progress of WS_(2)/WSe_(2)@graphene nanocomposites in electrochemical energy storage applications is summarized. Furthermore, various methods for the synthesis of WS_(2)/WSe_(2)@graphene nanocomposites are reported and the relationships among these methods, nano/microstructures, and electrochemical performance are systematically summarized and discussed. In addition, the challenges and prospects for the future study and application of WS_(2)/WSe_(2)@graphene nanocomposites in electrochemical energy storage applications are proposed.

关键词： WS_(2)/WSe_(2)@graphene nanocomposites Liion batteries(LIBs) Na-ion batteries(SIBs) Supercapacitors Electrochemical performance

Fe-N-C core-shell catalysts with single low-spin Fe(Ⅱ)-N_(4)species for oxygen reduction reaction and high-performance proton exchange membrane fuel cells

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Journal of Energy Chemistry 2024年第6期93卷 538-546,I0013页

作者： Yan Wan Linhui Yu Bingxin Yang Caihong Li Chen Fang Wei Guo Fang-Xing Xiao Yangming Lin Xiamen key laboratory of Rare Earth Photoelectric Functional Materials Xiamen Institute of Rare Earth MaterialsHaixi InstituteChinese Academy of SciencesXiamen 361021FujianChina CAS key laboratory of Urban Pollutant Conversion Institute of Urban EnvironmentChinese Academy of SciencesXiamen 361021FujianChina fujian Institute of research on the Structure of Matter Chinese Academy of SciencesFuzhou 350002FujianChina College of Materials Science and Engineering Fuzhou UniversityNew CampusMinhou 350108FujianChina College of Chemistry and Materials Science Fujian Normal UniversityFuzhou 350117FujianChina

Fe-N-doped carbon materials(Fe-N-C)are promising candidates for oxygen reduction reaction(ORR)relative to Pt-based catalysts in proton exchange membrane fuel cells(PEMFCs).However,the intrinsic contributions of Fe-N_(4)moiety with different chemical/spin states(e.g.D1,D2,D3)to ORR are unclear since various states coexist inevitably.In the present work,Fe-N-C core-shell nanocatalyst with single lowspin Fe(Ⅱ)-N_(4)species(D1)is synthesized and identified with ex-situ ultralow temperature Mossbauer spectroscopy(T=1.6 K)that could essentially differentiate various Fe-N_(4)states and invisible Fe-O species.By quantifying with CO-pulse chemisorption,site density and turnover frequency of Fe-N-C catalysts reach 2.4×10^(-9)site g^(-1)and 23 e site~(-1)s^(-1)during the ORR,respectively.Half-wave potential(0.915V_(RHE))of the Fe-N-C catalyst is more positive(approximately 54 mV)than that of Pt/C.Moreover,we observe that the performance of PEMFCs on Fe-N-C almost achieves the 2025 target of the US Department of Energy by demonstrating a current density of 1.037 A cm^(-2)combined with the peak power density of 0,685 W cm^(-2),suggesting the critical role of Fe(Ⅱ)-N_(4)site(D1).After 500 h of running,PEMFCs still deliver a power density of 1.26 W cm^(-2)at 1.0 bar H_(2)-O_(2),An unexpected rate-determining step is figured out by isotopic labelling experiment and theoretical calculation.This work not only offers valuable insights regarding the intrinsic contribution of Fe-N_(4)with a single spin state to alkaline/acidic ORR,but also provides great opportunities for developing high-performance stable PEMFCs.

关键词： Fuel cells Oxygen reduction reaction Non-platinum group metals(PGMs) Isotopic labelling Active site TOF

Effective protective agents against the organ toxicity of T-2 toxin and corresponding detoxification mechanisms: A narrative review

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Animal Nutrition 2024年第1期16卷 251-266页

作者： Pengju Wang Lv-hui Sun Xu Wang Qinghua Wu Aimei Liu Hubei key laboratory of Diabetes and Angiopathy Medicine Research Institute Xianning Medical College Hubei University of Science and Technology Hubei Hongshan laboratory College of Animal Science and Technology Huazhong Agricultural University National Reference laboratory of Veterinary Drug Residues (HZAU) and MAO key laboratory for Detection of Veterinary Drug Residues Huazhong Agricultural University College of Life Science Yangtze University

T-2 toxin is one of the most widespread and toxic fungal toxins in food and feed. It can cause gastrointestinal toxicity, hepatotoxicity, immunotoxicity, reproductive toxicity, neurotoxicity, and nephrotoxicity in humans and animals. T-2 toxin is physicochemically stable and does not readily degrade during food and feed processing. Therefore, suppressing T-2 toxin-induced organ toxicity through antidotes is an urgent issue. Protective agents against the organ toxicity of T-2 toxin have been recorded widely in the literature, but these protective agents and their molecular mechanisms of detoxification have not been comprehensively summarized. In this review, we provide an overview of the various protective agents to T-2 toxin and the molecular mechanisms underlying the detoxification effects. Targeting appropriate targets to antagonize T-2 toxin toxicity is also an important option. This review will provide essential guidance and strategies for the better application and development of T-2 toxin antidotes specific for organ toxicity in the future.

关键词： T-2 toxin Organ toxicity Protective agent Detoxification mechanism