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SHui, an EU-Chinese cooperative project to optimize soil and water management in agricultural areas in the ⅩⅪ century

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International Soil and Water Conservation Research 2020年第1期8卷 1-14页

作者： José A.Gómez Alon Ben-Gal Juan J.Alarcón Gabrielle De Lannoy Shannon de Roos Tomá(s)Dostál Elias Fereres Diego S.Intrigliolo Josef Krása Andreas Klik Gunther Liebhard Reinhard Nolz Aviva Peeters Elke Plaas John N.Quinton Rui Miao Peter Strauss Weifeng Xu Zhiqiang Zhang Funing Zhong David Zumr Ian C.Dodd Institute for Sustainable Agriculture IASCSICAvda Menendez Pidal S/NCordobaSpain Agricultural Research Organization Gilat Research CenterIsrael Centro de Edafología y Biología Aplicada Del Segura(CSIC) Dept.RiegoMurciaSpain Department of Earth and Environmental Sciences KU LeuvenHeverleeBelgium Czech Technical University in Prague Faculty of Civil Engineering.CVUTPragueCzech Republic Agronomy Department University of CordobaCordobaSpain University of Agricultural Sciences Vienna(BOKU) ViennaAustria TerraVision Lab Midreshet Ben-GurionIsrael Georg-August-Universitat Gottingen Germany Centre for Sustainable Agriculture Lancaster Environment CentreLancaster UniversityUK Center for Plant Water-Use and Nutrition Regulation and College of Life Sciences Joint International Research Laboratory of Water and Nutrient in CropsFujian Agriculture and Forestry UniversityFuzhouChina Institute for Land and Water Management Research Federal Agency for Water ManagementPetzenkirchenAustria College of Soil and Water Conservation Beijing Forestry UniversityBeijingChina College of Economics and Management Nanjing Agricultural UniversityNAUNanjingChina

This article outlines the major scientific objectives of the SHui project that seeks to optimize soil and water use in agricultural systems in the EU and China,by considering major current scientific challenges in this ***(for Soil Hydrology research platform underpinning innovation to manage water scarcity in European and Chinese cropping systems)is large cooperative project that aims to provide significant advances through transdisciplinary research at multiple scales(plot,field,catchment and region).This paper explains our research platform of long-term experiments established at plot scale,approaches taken to integrate crop and hydrological models at field scale;coupled crop models and satellite-based observations at regional scales;decision support systems for specific farming situations;and the integration of these technologies to provide policy recommendations through socio-economic analysis of the impact of soil and water saving *** also outlines the training of stake-holders to develop a basic common curriculum despite the subject being distributed across different disciplines and *** such,this article provides a review of major challenges for improving soil and water use in EU and China as well as information about the potential to access information made available by SHui,and to allow others to engage with the project.

关键词： Yield Sustainability Cropping Cooperation

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垂直排列的六方氮化硼基忆阻器中的突触可塑性

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Science China Materials 2024年第6期67卷 1907-1914页

作者：张海忠巨鑫江海涛杨丹魏榕山胡炜卢孝强朱敏敏 College of Physics and Information Engineering Fuzhou UniversityFuzhou 350116China Fuzhou University-Jinjiang Joint Institute of Microelectronics School of Advanced ManufacturingJinjiang Science and Education ParkFuzhou UniversityJinjiang 362200China Institute of Materials Research and Engineering Agency for ScienceTechnology and ResearchSingapore 138634Singapore

下一代计算系统需要实现每秒1018次浮点运算以解决感知终端数据呈指数增长的问题,这是由人工智能和物联网的进步驱动的.即使超级计算机具备执行这些操作的能力,但当电子突触阵列达到与人类神经网络相当规模时,管理热耗散就成为一个重要... 详细信息

下一代计算系统需要实现每秒1018次浮点运算以解决感知终端数据呈指数增长的问题,这是由人工智能和物联网的进步驱动的.即使超级计算机具备执行这些操作的能力,但当电子突触阵列达到与人类神经网络相当规模时,管理热耗散就成为一个重要挑战.解决电子设备中热点问题的潜在方案之一是使用垂直排列的六方氮化硼(h-BN),这种材料以其高导热性而闻名.在本研究中,我们使用高功率脉冲磁控溅射技术开发了纹理化的h-BN薄膜.定向的h-BN薄膜的热导率约为随机定向对应物的354%.通过制备基于纹理化h-BN薄膜的电子突触,我们展示了该器件中的各种生物突触可塑性.我们的研究结果表明,通过方向工程,可以有效使h-BN成为一种适用的自散热层,从而为未来可穿戴记忆设备、太阳能电池和神经形态器件铺平道路.

关键词： boron nitride vertically-aligned high thermal con-ductivity low-power memory neuromorphic computing

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Antitumor efficacy and potential mechanism of FAP-targeted radioligand therapy combined with immune checkpoint blockade

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Signal Transduction and Targeted Therapy 2024年第7期9卷 2936-2952页

作者： Liang Zhao Yizhen Pang Yangfan Zhou Jianhao Chen Hao Fu Wei Guo Weizhi Xu Xin Xue Guoqiang Su Long Sun Hua Wu Jingjing Zhang Zhanxiang Wang Qin Lin Xiaoyuan Chen Haojun Chen Department of Nuclear Medicine and Minnan PET Center Xiamen Key Laboratory of RadiopharmaceuticalsThe First Affiliated Hospital of Xiamen UniversitySchool of MedicineXiamen UniversityXiamenChina Departments of Diagnostic Radiology SurgeryChemical and Biomolecular Engineeringand Biomedical EngineeringYong Loo Lin School of Medicine and College of Design and EngineeringNational University of SingaporeSingaporeSingapore Clinical Imaging Research Centre Centre for Translational MedicineYong Loo Lin School of MedicineNational University of SingaporeSingaporeSingapore Department of Radiation Oncology Xiamen Cancer CenterXiamen Key Laboratory of Radiation OncologyThe First Affiliated Hospital of Xiamen UniversitySchool of MedicineXiamen UniversityXiamenChina Department of Colorectal Tumor Surgery Xiamen Cancer CenterXiamen Key Laboratory of Radiation OncologyThe First Affiliated Hospital of Xiamen UniversitySchool of MedicineXiamen UniversityXiamenChina Department of Cardiothoracic Surgery Zhongda HospitalSchool of MedicineSoutheast UniversityNanjingChina Nanomedicine Translational Research Program NUS Center for NanomedicineYong Loo Lin School of MedicineNational University of SingaporeSingaporeSingapore Department of Neurosurgery and Department of Neuroscience Fujian Key Laboratory of Brain Tumors Diagnosis and Precision TreatmentXiamen Key Laboratory of Brain Centerthe First Affiliated Hospital of Xiamen UniversitySchool of MedicineXiamen UniversityXiamenChina Institute of Molecular and Cell Biology Agency for ScienceTechnology and Research(A*STAR)SingaporeSingapore Xiamen Key Laboratory of Rare Earth Photoelectric Functional Materials Xiamen Institute of Rare Earth MaterialsHaixi InstituteChinese Academy of SciencesXiamenChina

Radiotherapy combined with immune checkpoint blockade holds great promise for synergistic antitumor *** radionuclide therapy delivers radiation directly to tumor ***1004 is a fibroblast activation protein(FAP)-targeting radiopharmaceutical,conjugated with the albumin binder Evans Blue,which has demonstrated enhanced tumor uptake and retention in previous preclinical and clinical ***,we demonstrate that^(68)Ga/^(177)Lu-labeled LNC1004 exhibits increased uptake and prolonged retention in MC38/NIH3T3-FAP and CT26/NIH3T3-FAP tumor *** therapy with^(177)Lu-LNC1004 induced a transient upregulation of PD-L1 expression in tumor *** combination of^(177)Lu-LNC1004 and anti-PD-L1 immunotherapy led to complete eradication of all tumors in MC38/NIH3T3-FAP tumor-bearing mice,with mice showing 100%tumor rejection upon ***,single-cell RNA sequencing(scRNA-seq),and TCR sequencing revealed that combination therapy reprogrammed the tumor microenvironment in mice to foster antitumor immunity by suppressing malignant progression and increasing cell-to-cell communication,CD8^(+)T-cell activation and expansion,M1 macrophage counts,antitumor activity of neutrophils,and T-cell receptor diversity.A preliminary clinical study demonstrated that^(177)Lu-LNC1004 was well-tolerated and effective in patients with refractory ***,scRNA-seq of peripheral blood mononuclear cells underscored the importance of addressing immune evasion through immune checkpoint blockade *** was emphasized by the observed increase in antigen processing and presentation juxtaposed with T cell *** conclusion,our data supported the efficacy of immunotherapy combined with^(177)Lu-LNC1004 for cancer patients with FAP-positive tumors.

关键词： immunity retention holds

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Catalytically altering the redox pathway of sulfur in propylene carbonate electrolyte using dual-nitrogen/oxygen-containing carbon

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Chinese Journal of Catalysis 2024年第8期63卷 224-233页

作者： Linghui Yu Heng Zhang Luyuan Paul Wang Samuel Jun Hoong Ong Shibo Xi Bo Chen Rui Guo Ting Wang Yonghua Du Wei Chen Ovadia Lev Zhichuan J.Xu School of Chemistry and Chemical Engineering Wuhan Textile UniversityWuhan 430200HubeiChina School of Materials Science and Engineering Nanyang Technological UniversitySingapore 639798Singapore Hubei Key Laboratory of Biomass Fibers&Eco-Dyeing&Finishing Wuhan Textile UniversityWuhan 430200HubeiChina Institute of Sustainability for Chemicals Energy and Environment(ISCE2)Agency for ScienceTechnology and Research in Singapore(A*STAR)1 Pesek RoadJurong Island 627833Singapore Department of Chemistry National University of SingaporeSingapore 117543Singapore College of the Environment&Ecology Xiamen UniversityXiamen 361102FujianChina National Synchrotron Light Source II Brookhaven National LaboratoryUptonNY 11973USA The Institute of Chemistry The Hebrew University of JerusalemJerusalem 9190401Israel Singapore-HUJ Alliance for Research and Enterprise NEW-CREATE Phase IICampus for Research Excellence and Technological Enterprise(CREATE)Singapore138602Singapore Energy Research Institute@NTU ERI@NInterdisciplinary Graduate SchoolNanyang Technological UniversitySingapore 639798Singapore

Carbonate electrolytes are one of the most desirable electrolytes for high-energy lithium-sulfur batteries(LSBs)because of their successful implementation in commercial Li-ion *** low-polysulfide-solubility feature of some carbonate solvents also makes them very promising for overcoming the shuttle effects of ***,regular sulfur electrodes experience undesired electrochemical mechanisms in carbonate electrolytes due to side *** this study,we report a catalytic redox mechanism of sulfur in propylene carbonate(PC)electrolyte based on a compari-son *** catalytic mechanism is characterized by the interactions between polysulfides and dual N/O functional groups on the host carbon,which largely prevents side reactions between polysulfides and the carbonate *** a mechanism coupled with the low-polysulfide-solubility feature leads to stable cycling of LSBs in PC *** dual N/O functional groups are identified via a density functional theory *** work provides an alternative route for enabling LSBs in carbonate electrolytes.

关键词： Energy storage Lithium-sulfur battery Catalytic redox reaction Porous carbon Carbonate electrolyte

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Dielectric metasurface evolution from bulk to monolayer by strong coupling of quasi-BICs for second harmonic boosting

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Photonics Research 2024年第4期12卷 784-792页

作者： YINONG XIE QIANTING CHEN JIN YAO XUEYING LIU ZHAOGANG DONG JINFENG ZHU Institute of Electromagnetics and Acoustics and Key Laboratory of Electromagnetic Wave Science and Detection Technology Xiamen UniversityXiamen 361005China Shenzhen Research Institute of Xiamen University Shenzhen 518057China Department of Electrical Engineering City University of Hong KongHong Kong 999077China Institute of Materials Research and Engineering(IMRE) Agency for ScienceTechnology and Research(A*STAR)Singapore 138634Singapore Department of Materials Science and Engineering National University of SingaporeSingapore 117575Singapore

2D materials are promising candidates as nonlinear optical components for on-chip devices due to their ultrathin structure. In general, their nonlinear optical responses are inherently weak due to the short interaction thickness with light. Recently, there has been great interest in using quasi-bound states in the continuum (q-BICs) of dielectric metasurfaces, which are able to achieve remarkable optical near-field enhancement for elevating the second harmonic generation (SHG) emission from 2D materials. However, most studies focus on the design of combining bulk dielectric metasurfaces with unpatterned 2D materials, which suffer considerable radiation loss and limit near-field enhancement by high-quality q-BIC resonances. Here, we investigate the dielectric metasurface evolution from bulk silicon to monolayer molybdenum disulfide (MoS2), and discover the critical role of meta-atom thickness design on enhancing near-field effects of two q-BIC modes. We further introduce the strongcoupling of the two q-BIC modes by oblique incidence manipulation, and enhance the localized optical field on monolayer MoS2dramatically. In the ultraviolet and visible regions, the MoS2SHG enhancement factor of our design is 105times higher than that of conventional bulk metasurfaces, leading to an extremely high nonlinear conversion efficiency of 5.8%. Our research will provide an important theoretical guide for the design of high-performance nonlinear devices based on 2D materials.

关键词： monolayer harmonic quasi

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Whole-genome sequencing provides insights into the genetic diversity and domestication of bitter gourd(Momordica spp.)

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Horticulture Research 2020年第1期7卷 1758-1768页

作者： Junjie Cui Yan Yang Shaobo Luo Le Wang Rukui Huang Qingfang Wen Xiaoxia Han Nansheng Miao Jiaowen Cheng Ziji Liu Changyuan Zhang Chengcheng Feng Haisheng Zhu Jianwen Su Xinjian Wan Fang Hu Yu Niu Xiaoming Zheng Yulan Yang Dai Shan Zhensheng Dong Weiming He Narinder P.S.Dhillon Kailin Hu College of Horticulture South China Agricultural University/State Key Laboratory for Conservation and Utilization of Subtropical Agro-bioresources/Key Laboratory of Biology and Genetic Improvement of Horticultural Crops(South China)Ministry of Agriculture and Rural Affairs510642 GuangzhouChina Tropical Crop Genetic Resources Institute Chinese Academy of Tropical Agricultural Sciences571737 DanzhouChina Vegetable Research Institute Guangdong Academy of Agricultural Sciences510640 GuangzhouChina BGI Genomics BGI-Shenzhen518083 ShenzhenChina Vegetable Research Institute Guangxi Academy of Agricultural Sciences530007 NanningChina Crop Research Institute Fujian Academy of Agricultural Sciences350013 FuzhouChina Institute of Vegetable Research Hunan Academy of Agricultural Sciences410125 ChangshaChina Institute of Vegetables and Flowers Jiangxi Academy of Agricultural Sciences330200 NanchangChina World Vegetable Center East and Southeast AsiaResearch and Training StationKasetsart UniversityKamphaeng SaenNakhon Pathom 73140Thailand

Bitter gourd(Momordica charantia)is a popular cultivated vegetable in Asian and African *** reveal the characteristics of the genomic structure,evolutionary trajectory,and genetic basis underlying the domestication of bitter gourd,we performed whole-genome sequencing of the cultivar Dali-11 and the wild small-fruited line TR and resequencing of 187 bitter gourd germplasms from 16 *** major gene clusters(Bi clusters)for the biosynthesis of cucurbitane triterpenoids,which confer a bitter taste,are highly conserved in cucumber,melon,and *** analysis among cucurbit genomes revealed that the Bi cluster involved in cucurbitane triterpenoid biosynthesis is absent in bitter *** analysis revealed that the TR group,including 21 bitter gourd germplasms,may belong to a new species or subspecies independent from ***,we found that the remaining 166 *** germplasms are geographically differentiated,and we identified 710,412,and 290 candidate domestication genes in the South Asia,Southeast Asia,and China populations,*** study provides new insights into bitter gourd genetic diversity and domestication and will facilitate the future genomics-enabled improvement of bitter gourd.

关键词： insight cluster Whole

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