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Problem identification and revitalization strategies for the recovery and reconstruction of traditional villages in the Ms 6.8 Luding Earthquake

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Journal of Mountain Science 2024年第2期21卷 361-379页

作者： HUANG Chao QIU Jian LIU Chun JIANG Rui ZHAO Chuanrong ZHANG Yi School of Architecture and research Center of Space planning and Engineering Design Southwest Jiaotong UniversityChengdu 611756China sichuan Provincial Rural Construction and Development Center Chengdu 610041China sichuan institute of Urban and Rural Construction Chengdu 610043China China Association for Promoting Democracy(CAPD)sichuan Provincial Committee Chengdu 610016China sichuan Provincial Architectural Design and research institute(SADI) Chengdu 610095China

Post-disaster reconstruction is a topic of global concern,and traditional villages have special heritage attributes and need to face more requirements and obstacles in post-disaster *** paper summarizes four concepts based on the research on post-disaster reconstruction both domestically and internationally,as well as the recovery and reconstruction of cultural *** a field survey of traditional villages in the Ms 6.8 Luding earthquake-stricken area,it is found that there are problems such as insufficient awareness of heritage value,misalignment of scientific reconstruction technology,and insufficient protection of reconstruction elements during the reconstruction *** villages face the risk of declining or even loss of heritage *** order to effectively protect traditional villages and inherit the carrier of regional culture,four targeted reconstruction response strategies are proposed,i.e.,to"establish special planning for traditional village preservation","emphasize recovery of the authenticity of village heritage","ensure elements for village heritage recovery"and"promote the activation and utilization of village heritage",based on the problems discovered during the survey and the four concepts summarized in the research on post-disaster reconstruction of traditional *** research results hope to provide useful reference for ancient cultural areas affected by earthquakes on how to protect cultural heritage during the post-disaster reconstruction process.

关键词： Seismic hazard Decision making Traditional village Cultural heritage protection Post-earthquake recovery and reconstruction Revitalization strategy

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Airblast evolution initiated by Wangjiayan landslides in the M_(s)8.0 Wenchuan earthquake and its destructive capacity analysis

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China Geology 2024年第2期7卷 237-247页

作者： Yu-feng Wang Qian-gong Cheng Qi Zhu Department of Geological Engineering Southwest Jiaotong UniversityChengdu 610031China sichuan Highway planning SurveyDesign and Research Institute LtdChengdu 610041China

Airblasts,as one common phenomenon accompanied by rapid movements of landslides or rock/snow avalanches,commonly result in catastrophic damages and are attracting more and more scientific *** quantitatively analyze the intensity of airblast initiated by landslides,the Wangjiayan landslide,occurred in the Wenchuan earthquake,is selected here with the landslide propagation and airblast evolution being studied using FLUENT by introducing the Voellmy rheological *** results reveal that:(1)For the Wangjiayan landslide,its whole travelling duration is only 12 s with its maximum velocity reaching 36 m/s at t=10 s;(2)corresponding to the landslide propagation,the maximum velocity,28 m/s,of the airblast initiated by the landslide also appears at t=10 s with its maximum pressure reaching594.8 Pa,which is equivalent to violent storm;(3)under the attack of airblast,the load suffered by buildings in the airblast zone increases to 1300 Pa at t=9.4 s and sharply decreased to-7000 Pa as the rapid decrease of the velocity of the sliding mass at t=10 s,which is seriously unfavorable for buildings and might be the key reason for the destructive collapse of buildings in the airblast zone of the Wangjiayan landslide.

关键词： Landslide Voellmy rheological law 3D FLUENT simulation Airblast Intensity Building destructive collapse Wenchuan earthquake Geological hazards survey engineering

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The current situation of semen analysis in China,based on a survey of 296 laboratories

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Asian Journal of Andrology 2024年第2期26卷 220-221页

作者： Long-Long Fu Ying Liu Xiao-Wei Wang Fang Zhou Ying Guo Wen-Hong Lu Yi-Qun Gu National Health Commission Key Laboratory of Male Reproductive Health Reproductive Health Research CenterNational Research Institute for Family PlanningBeijing 100081China institute of Pediatric research Children's Hospitalof Soochow UniversitySuzhou 215025China

Dear Editor,Semen analysis is a basic test to assess male fertility and is a fundamental test in assisted reproductive *** the first publication of World Health Organization(WHO)Laboratory Manual of Human Semen and Sperm-Cervical Mucus Interaction in 1980,to the publication of the WHO Manual,6th edition in 2021,these 40 years have been recognized as providing a global standard that is widely used in research and clinical laboratories *** WHO Manual,6th edition in Chinese,which we have been authorized by the WHO to translate,will be published soon.

关键词： technology. analysis translate

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Investigating the mechanisms of isochorismate synthase:An approach to improve salicylic acid synthesis and increase resistance to Fusarium head blight in wheat

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The Crop Journal 2024年第4期12卷 1054-1063页

作者： Ya-Zhou Zhang Jie Man Dan Xu Lan Wen Yinghui Li Mei Deng Qian-Tao Jiang Qiang Xu Guo-Yue Chen Yu-Ming Wei State Key Laboratory of Crop Gene Exploration and Utilization in Southwest China Sichuan Agricultural UniversityChengdu 611130SichuanChina Triticeae research institute Sichuan Agricultural UniversityChengdu 611130SichuanChina

Salicylic acid(SA),a vital endogenous hormone,plays a crucial role in plant growth and the response to abiotic and biotic *** synthase(ICS)and phenylalanine ammonia lyase(PAL)are critical rate-limiting enzymes for SA *** head blight(FHB)seriously threatens the safety of wheat production,but increasing the content of SA can enhance FHB ***,the pathway of SA synthesis and regulation in wheat remains *** this study,three wheat ICS(TaICSA,TaICSB,and TaICSD)were identified,and their functions were validated in vitro for isomerizing chorismate to *** mutation of one or two homoeoalleles of TaICSA,TaICSB,and TaICSD in the wheat variety‘Cadenza’reduced SA levels under ultraviolet treatment and Fusarium graminearum infection,further enhancing sensitivity to *** of TaICSA can significantly enhance SA levels and resistance to *** further study SA synthesis pathways in wheat and avoid interference with pathogenicity related genes,the leaves of wild-type Cadenza and different TaICS mutant lines were subjected to ultraviolet treatment for transcriptomic *** results showed that 37 PALs might be involved in endogenous SA synthesis,and 82 WRKY and MYB family transcription factors may regulate the expression of ICS and *** results were further confirmed by *** conclusion,this study expands our knowledge of SA biosynthesis and identifies TaICSA,as well as several additional candidate genes that encode transcription factors for regulating endogenous SA levels,as part of an efficient strategy for enhancing FHB resistance in wheat.

关键词： Salicylic acid Chorismate Isochorismate RNA-seq Phenylalamine ammonia lyase

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Estimates of net primary productivity and actual evapotranspiration over the Tibetan Plateau from the Community Land Model version 4.5 with four atmospheric forcing datasets

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Journal of Plant Ecology 2024年第4期17卷 70-89页

作者： Shan Lin Kewei Huang Xiangyang Sun Chunlin Song Juying Sun Shouqin Sun Genxu Wang Zhaoyong Hu State Key Laboratory of Hydraulics and Mountain River Engineering College of Water Resource and HydropowerSichuan UniversityChengdu 610065China Hubei Key Laboratory of Basin Water Security Changjiang SurveyPlanningDesign and Research Co.Ltd.Wuhan 430010China research Unit Forest Dynamics Swiss Federal Research Institute for ForestSnow and Landscape Research WSLBirmensdorf 8903Switzerland

The accuracy of the simulation of carbon and water processes largely relies on the selection of atmospheric forcing datasets when driving land surface models(LSM).Particularly in high-altitude regions,choosing appropriate atmospheric forcing datasets can effectively reduce uncertainties in the LSM ***,this study conducted four offline LSM simulations over the Tibetan Plateau(TP)using the Community Land Model version 4.5(CLM4.5)driven by four state-of-the-art atmospheric forcing *** performances of CRUNCEP(CLM4.5 model default)and three other reanalysis-based atmospheric forcing datasets(***,GSWP3 and WFDEI)in simulating the net primary productivity(NPP)and actual evapotranspiration(ET)were evaluated based on in situ and gridded reference *** with in situ observations,simulated results exhibited determination coefficients(R2)ranging from 0.58 to 0.84 and 0.59 to 0.87 for observed NPP and ET,respectively,among which GSWP3 and ITPCAS showed superior *** the plateau level,CRUNCEP-based simulations displayed the largest bias compared with the reference NPP and ***3-based simulations demonstrated the best performance when comprehensively considering both the magnitudes and change trends of TP-averaged NPP and *** simulated ET increase over the TP during 1982-2010 based on ITPCAS was significantly greater than in the other three simulations and reference ET,suggesting that ITPCAS may not be appropriate for studying long-term ET changes over the *** results suggest that GSWP3 is recommended for driving CLM4.5 in conducting long-term carbon and water processes simulations over the *** study contributes to enhancing the accuracy of LSM in water-carbon simulations over alpine regions.

关键词： land surface model carbon cycle water cycle high altitude Community Land Model version 4.5

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Dynamic Identification and Evolution of Urban-suburban-rural Transition Zones Based on the Blender of Natural and Humanistic Factors: A Case Study of Chengdu, China

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Chinese Geographical Science 2024年第5期34卷 791-809页

作者： DENG Wei JIANG Zhenyuan ZHANG Shaoyao REN Ping ZHANG Hao WANG Zhanyun The Faculty Geography Resources Science Sichuan Normal UniversityChengdu 610101China Sustainable Development research Center of Resources and Environment in Western sichuan Sichuan Normal UniversityChengdu 610101China institute of Mountain Hazards and Environment Chinese Academy of SciencesChengdu 610041China

Urban-suburban-rural(U-S-R)zones exhibit distinctive transitional characteristics in interaction between human and nature.U-S-R transition zones(U-S-RTZ)are also highlighting the function diversity and landscape heterogeneity across territorial *** a super megacity in western China,Chengdu’s rapid urbanization has driven the evolution of U-S-R spaces,resulting in a sequential *** promote the high-quality spatial development of urban-rural region in a structured and efficient manner,it is essential to con-duct a scientific examination of the multidimensional interconnection within the U-S-RTZ *** proposing a novel identifica-tion method of U-S-RTZ and taking Chengdu,China as a case study,grounded in a blender of natural and humanistic factors,this study quantitatively delineated and explored the spatial evolutions of U-S-RTZ and stated the optimization orientation and sustainable devel-opment strategies of the production-living-ecological spaces along the U-S-R *** results show that:1)it is suitable for the quantitative analysis of U-S-RTZ by established three-dimensional identification system in this study.2)In 1990-2020,the urban-sub-urban transition zones(U-STZ)in Chengdu have continuously undergone a substantial increase,and the scale of the suburban-rural transition zones(S-RTZ)has continued to expand slightly,while the space of rural-ecological transition zones(R-ETZ)has noticeably compressed.3)The landuse dynamics within U-S-RTZ has gradually increased in *** main direction of landuse transition was from farmland to construction land or woodlands,with the expansion of construction land being the most significant.4)R-ETZ primarily focus on ecological functions,and there is a trade-off relationship between the production-ecological function within the S-RTZ,and in the U-STZ,production-living composite functions are *** study emphasizes the importance of elastic planning and precise governance within the U-

关键词： transition zone urban-suburban-rural zones spatial identification evolution mechanism Chengdu,China

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Melatonin improves synapse development by PI3K/Akt signaling in a mouse model of autism spectrum disorder

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Neural Regeneration research 2024年第7期19卷 1618-1624页

作者： Luyi Wang Man Xu Yan Wang Feifei Wang Jing Deng Xiaoya Wang Yu Zhao Ailing Liao Feng Yang Shali Wang Yingbo Li institute of Neuroscience Department of PhysiologySchool of Basic Medical ScienceChongqing Medical UniversityChongqingChina Department of Pediatric Chongqing University Fuling HospitalChongqingChina Department of Neurosurgery Xinqiao HospitalArmy Medical UniversityChongqingChina Department of Pathology Affiliated Hospital of North Sichuan Medical CollegeNanchongSichuan ProvinceChina NHC Key Laboratory of Birth Defects and Reproductive Health Chongqing Population and Family Planning Science and Technology Research InstituteChongqingChina China National Clinical research Center for Neurological Diseases Beijing Tiantan HospitalCapital Medical UniversityBeijingChina Advanced Innovation Center for Human Brain Protection Capital Medical UniversityBeijingChina

Autism spectrum disorders are a group of neurodevelopmental disorders involving more than 1100 genes,including Ctnnd2 as a candidate ***2knockout mice,serving as an animal model of autis m,have been demonstrated to exhibit decreased density of dendritic *** role of melatonin,as a neuro hormone capable of effectively alleviating social interaction deficits and regulating the development of dendritic spines,in Ctnnd2 deletion-induced nerve injury remains unclea *** the present study,we discove red that the deletion of exon 2 of the Ctnnd2 gene was linked to social interaction deficits,spine loss,impaired inhibitory neurons,and suppressed phosphatidylinositol-3-kinase(PI3K)/protein kinase B(Akt) signal pathway in the prefrontal *** findings demonstrated that the long-term oral administration of melatonin for 28 days effectively alleviated the aforementioned abnormalities in Ctnnd2 gene-knockout ***,the administration of melatonin in the prefro ntal cortex was found to improve synaptic function and activate the PI3K/Akt signal pathway in this *** pharmacological blockade of the PI3K/Akt signal pathway with a PI3K/Akt inhibitor,wo rtmannin,and melatonin receptor antagonists,luzindole and 4-phenyl-2-propionamidotetralin,prevented the melatonin-induced enhancement of GABAergic synaptic *** findings suggest that melatonin treatment can ameliorate GABAe rgic synaptic function by activating the PI3K/Akt signal pathway,which may contribute to the improvement of dendritic spine abnormalities in autism spectrum disorders.

关键词： autism Ctnnd2 deletion GABAergic neurons melatonin PI3K/Akt signal pathway prefrontal cortex social behavior spine density synaptic-associated proteins

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Luminescent Zinc Porphyrinic MOF as a Ratiometric Fluorescence Sensor for Determination of Tetracycline Hydrochloride

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Food Science and Human Wellness 2024年

作者： Quanbin Fu Feijiao Hu Wenyuan Tan Qiaofeng Zhai Juying Hou Houshen Li Zhiyong Hu Yijing Li Geoffrey I.N.Waterhouse Shiyun Ai College of Food Science and Engineering， Shandong Agricultural University College of Chemistry and Material Science， Shandong Agricultural University sichuan Engineering Technology research Center for High Salt Wastewater Treatment and Resource Utilization， sichuan University of Science and Engineering Tai'an planning and Compilation research Center (Tai'an institute of planning and Design Tai'an planning Exhibition Hall) College of Animal Science and Technology， Shandong Agricultural University School of Chemical Sciences， The University of Auckland

Two-dimensional luminescent metal-organic frameworks （2D LMOFs）， have garnered significant attention for their unique fluorescent properties and highly accessible active sites， yet designing these LMOFs with target-dependent fluorescence for sensing remains a challenging endeavor. Herein， a zinc tetra（4-carboxyphenyl）porphine （Zn-TCPP） LMOF was prepared and first applied to the fast and sensitive sensing of tetracycline hydrochloride （TCH）. Upon TCH exposure， the signature red fluorescence of Zn-TCPP at 609 nm diminishes， accompanied by the emergence of a 520 nm peak， which were originated from photo-induced electron transfer （PET） of Zn-TCPP to TCH and inner filter effect （IFE） of TCH towards Zn-TCPP， and the triggers of Zn-TCPP on the instinct fluorescence of TCH， respectively. Notably， the I520/I609fluorescence intensity ratio showed good linearity over a wide range of TCH concentrations （0.1-25 μmol/L）， with a limit of detection （LOD） of 65.4 nmol/L. Additionally， the Zn-TCPP probe showed good TCH selectivity and anti-interference properties. The probe’s practicability was also validated by detecting TCH in spiked tap water， milk and chicken samples. Furthermore， test papers impregnated with the Zn-TCPP probe were prepared， allowing the visual detection of TCH with a smartphone. Results suggest the developed method is suitable for practical TCH detection.

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Gga-miRNA-181-5p family facilitates chicken myogenesis via targeting TGFBR1 to block TGF-βsignaling

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Journal of Integrative Agriculture 2024年第8期23卷 2764-2777页

作者： Xiaoxu Shen Yongtong Tian Wentao He Can He Shunshun Han Yao Han Lu Xia Bo Tan Menggen Ma Houyang Kang Jie Yu Qing Zhu Huadong Yin Key Laboratory of Livestock and Poultry Multi-omics Ministry of Agriculture and Rural AffairsCollege of Animal Science and TechnologySichuan Agricultural UniversityChengdu 611130China Farm Animal Genetic Resources Exploration and Innovation Key Laboratory of sichuan Province Sichuan Agricultural UniversityChengdu 611130China College of Forestry Sichuan Agricultural UniversityChengdu 611130China College of Resources Sichuan Agricultural UniversityChengdu 611130China Triticeae research institute Sichuan Agricultural UniversityChengdu 611130China Key Laboratory for Animal Disease Resistance Nutrition of China Institute of Animal NutritionMinistry of Education/Sichuan Agricultural UniversityChengdu 611130China

MicroRNAs(miRNAs)have been demonstrated to control chicken skeletal muscle growth,however,the potential function of the miR-181-5p family in chicken myogenesis remains largely ***,our study identified the two chicken(Gallus gallus;Gga)miR-181-5p family members widely expressed in various tissues,specifically miR-181a-5p and ***,the breast muscles of fast-growing broilers expressed higher levels of miR-181a-5p and miR-181b-5p than those of slow-growing ***,miR-181a-5p and miR-181b-5p both promote the expression level of myogenic factors including myogenin(MyoG),myogenic differentiation 1(MyoD1),and myosin heavy chain(MyHC),meanwhile accelerating the myotube formation of skeletal muscle satellite cells(SMSCs).Mechanistically,miR-181a-5p and miR-181b-5p directly bind to the 3′untranslated region(UTR)of the transforming growth factor beta receptor 1(TGFBR1)mRNA,further reducing the expression of ***1 is a key Transforming growth factor beta(TGF-β)signaling transduction receptor and had a negative function in muscle cell ***,knockdown of TGFBR1 facilitated the expression of chicken myogenic factors,boosted myotube formation,and decreased the SMAD family member 2/3(SMAD2/3)phosphorylation in chicken ***2/3 are downstream of TGF-βsignaling,and miR-181a-5p and miR-181b-5p could reduce the expression of TGFBR1 to further diminish the SMAD2/3 *** findings revealed that the miR-181-5p family targets TGFBR1 to break the TGF-βsignaling transduction,which resulted in promoting chicken skeletal muscle development.

关键词： miRNA-181-5p family SMSCs differentiation TGFBR1 TGF-βsignaling

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Electrical Characteristics of Tangjiawan Landslide in Lixian, sichuan

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Applied Geophysics 2024年第3期21卷 549-563,619页

作者： Bin Li Qiang Xu Qiang Cheng Tian-Xiang Liu Jian-hua Yu Yu-jie Su Feng Wang sichuan Highway planning SurveyDesign and Research Institute Ltd.SichuanChengdu 610041China Chengdu University of Technology State Key Laboratory of Geohazard Prevention and Geoenvironment ProtectionSichuanChengdu 610059China

A wide range of terrain features and landforms,which are exemplified by intricate geological formations and diverse rock compositions,are found in the western mountainous regions of *** areas frequently encounter geological *** one of the natural disasters,landslides lead to considerable loss of human life and *** mitigation of the losses caused by landslide disasters,a necessary measure for disaster prevention and mitigation involves conducting detailed investigations and monitoring of landslides,which is also the cornerstone of landslide *** study compares and analyzes the feasibility of the magnetotelluric detection method for landslides using the results of engineering geological surveys and landslide *** study aims to address the scientific problem of the validity of using magnetotelluric methods to detect landslide development *** Tangjiawan landslide signal on the left side of the K94+000~K94+145 section of the Wenma Expressway is analyzed by employing engineering geological survey,magnetotelluric detection,landslide monitoring,landslide analysis,and other *** results provide the static electrical characteristics of lithology,structure,and groundwater,as well as the dynamic electrical characteristics of landslide *** study focuses on analyzing the relationship between the methods of magnetotelluric detection and engineering geological surveys and the results of landslide *** workflow and methods for data collection,processing,inversion,interpretation,and analysis using the magnetotelluric method to detect the dynamic development process of landslides are presented in the *** conclusions indicate a strong correlation between the dynamic changes in magnetotelluric wave impedance with the surface displacement of landslides and the dynamic changes in *** use of the magnetotelluric method for landslide detection and monitoring is a fe

关键词： Landslide Magnetotelluric method Geophysics Engineering Geology Landslide Monitoring

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