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Fast synthesis of gold nanoparticles by cold atmospheric pressure plasma jet in the presence of Au^(+) ions and a capping agent

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Plasma Science and Technology 2024年第7期26卷 108-115页

作者： Tatiana HABIB José Mauricio A.CAIUT Bruno CAILLIER Laboratoire Diagnostics des Plasmas Hors Equilibre(DPHE) Universitéde ToulouseINU ChampollionAlbi 81000France Department of Chemistry The Nanomaterials and Luminescent Systems GroupFaculty of PhilosophyScience and Letters at Ribeirão PretoUniversity of São PauloRibeirão Preto-SP 14040-901Brazil

Homogeneous gold nanoparticles were synthesized under atmospheric pressure using a nonthermal helium plasma jet in a single-step process.A current power supply was used to generate the plasma discharge rich in diverse reactive *** species induce rapid chemical reactions responsible for the reduction of the gold salts upon contact with the liquid *** this study,spherical and monodispersed gold nanoparticles were obtained within 5 min of plasma exposure using a solution containing gold(Ⅲ)chloride hydrate(HAuCl_(4))as a precursor and polyvinylpyrrolidone(PVP)as a capping agent to inhibit *** formation of these metal nanoparticles was initially perceptible through a visible change in the sample's color,transitioning from light yellow to a red/pink *** was subsequently corroborated by UVvis spectroscopy,which revealed an optical absorption in the 520-550 nm range for Au NPs,corresponding to the surface plasmon resonance(SPR)*** investigation into the impact of various parameters,including plasma discharge duration,precursor and capping agent concentrations,was carried out to optimize conditions for the formation of well-separated,spherical gold *** light scattering(DLS)was used to measure the size of these nanoparticles,transmission electron microscopy(TEM)was used to observe their morphology and X-ray diffraction(XRD)was also employed to determine their crystallographic *** results confirm that homogeneous spherical gold nanoparticles with an average diameter of 13 nm can be easily synthesized through a rapid,straightforward,and environmentally friendly approach utilizing a helium atmospheric pressure plasma.

关键词： gold nanoparticles non-thermal plasma jet helium DBD

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History Teacher Training from Decolonial Curriculum Practices to Combat Racism at UniProjeção in the Federal District-A Secondary Publication

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Journal of Contemporary Educational Research 2024年第2期8卷 187-202页

作者： Karoline da Silva Ramos Cláudia Pinheiro Nascimento Francisca Carla Santos Ferrer faculty of philosophy Languages and Human SciencesUniversity of São PauloSão PauloBrazil

This article aims to understand the training process of history undergraduates,to see if there are decolonial curricular practices to combat racism at the Centro Universitário e Faculdade Projeção(UniProjeção)in the Federal District,to understand how coloniality has corroborated the exclusion of different epistemologies and the erasure of different cultures,and how this exclusionary process of coloniality interferes in the training of history *** order to combat this practice,we are looking for alternatives that can break these suppressions carried out by *** this way,we turn to decolonial ideas that aim to break with the logic of *** can conclude that these practices are poorly developed in the institution,so we proposed active problem-based methodology and music as a didactic *** playful educational tools that strengthen the teaching-learning process,they are active agents in the decolonial work of combating racism,and it is essential to train responsible and ethical teachers in the fight against racism and any form of oppression.

关键词： Coloniality Decoloniality Education Curriculum practices Racism

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Between Euthanasia and Dysthanasia: The Ethical Issue of Sedation in the Terminal Phase of Illness

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Journal of Biosciences and Medicines 2024年第2期12卷 39-49页

作者： Joseph Sawadogo faculty of Human and Social sciences Department of Philosophy Faculty of Medicine University Saint Thomas d’Aquin (USTA) Ouagadougou Burkina Faso

Background: Deep sedation, euthanasia and therapeutic relentlessness lead us today to rethink the paradigm of life and the contingency of human existence. Between therapeutic relentlessness, the unreasonable care which uses heavy therapeutic means which are often disproportionate to the expected benefit, namely keeping alive a patient whose condition is considered medically hopeless;and euthanasia which would precipitate the process of death would be sedation in the terminal phase of the illness. Should doctors and families of comatose patients decide the “life” and “death” of their patients? For anti-euthanasia associations, doctors, relatives of terminally ill patients and the State itself, if they accept the principle of euthanasia, they are “murderers”, while for pro-euthanasists, the dignity of the human being would recommend that the days of patients in situations considered critical be shortened, to avoid unnecessary suffering and humiliation. Methods: A systematic review of the literature was carried out to identify relevant articles relating to euthanasia, dysthanasia and sedation in the terminal phase of illness. The search was conducted in French or English in three databases: PubMed, Google Scholar and Science Direct. Objectives: The objectives of this article are: 1) define the terminologies and concepts of palliative sedation, deep sedation, deep and continuous sedation until death, euthanasia and dysthanasia;2) present aspects of the meaning of life and the human person in African cultures;and 3) propose an ethical reflection on the value of life. Results: After precisely defining the concepts of euthanasia, dysthanasia and sedation, this research presented the African anthropological and ethical approach to the mysteries of life and death. Conclusion: With this in mind, the golden rule of medicine always remains as such “Primum non nocere”.

关键词： Euthanasia Dysthanasia End-Of-Life Sedation Palliative Care African Cultures

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Monitor and Acceptance among Couples in Romantic Relationships:Actor-Partner Interdependence Models Based on the Monitor and Acceptance Theory

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International Journal of Mental Health Promotion 2024年第7期26卷 589-598页

作者： Xue Wen Yuyang Zhou Jiaxuan Du Xiaoyan Liu Wei Xu Beijing Key Laboratory of Applied Experimental Psychology National Demonstration Center for Experimental Psychology Education(Beijing Normal University)Faculty of PsychologyBeijing Normal UniversityBeijing100875China School of Psychology Nanjing Normal UniversityNanjing210097China College of Business Florida International UniversityMiamiFL 11200USA School of philosophy Psychology and Language SciencesUniversity of EdinburghEdinburghEH89YLUK

Communication could be an essential part of couples in their daily *** on Monitor and Acceptance Theory(MAT),the present study explored the mediating role of communication in the relationship between mindfulness and relationship quality among college-student *** research examined the dynamic relationship of monitoring and acceptance to relationship satisfaction in the Actor-Partner Interdependence Model(APIM),and the mediating effect of positive or negative communications in these relationships.A total of 96 pairs of couples in the universities in Nanjing,China participated in the *** measurements were used to measure the momentary levels of their monitor,acceptance,positive/negative communication,and relationship satisfaction.A Hierarchical Linear Model(HLM)was used to deal with the *** showed that the women’s monitor facet of state mindfulness negatively predicted men’s relationship satisfaction through women’s negative communication,and the women’s acceptance facet of state mindfulness positively predicted women’s relationship satisfaction through women’s positive and negative communication at the within-person *** study highlights the importance of cooperation in monitoring and acceptance for couples to own and hold high levels of relationship satisfaction.

关键词： Romantic relationship communication mindfulness monitor acceptance

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Structural and functional differences in the brains of patients with MCI with and without depressive symptoms and their relations with Alzheimer's disease:an MRI study

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Psychoradiology 2023年第1期3卷 182-192页

作者： Rodolfo Dias Chiari-Correia Vitor Tumas Antonio Carlos Santos Carlos Emesto G Salmon Department of Neurosciences and Behavioral sciences Ribeirao Preto Medical SchoolUniversity of Sao Paulo3900 Bandeirantes AvenueRibeirao Preto SP14040-900Brazil Department of Medical Imaging Hematology and Clinical OncologyRibeirao Preto Medical SchoolUniversity of Sao Paulo3900 Bandeirantes AvenueRibeirao Preto SP14040-900Brazil Department of Physics Faculty of PhilosophySciences and LettersUniversity of Sao Paulo3900 Bandeirantes AvenueRibeirao Preto SP14040-900Brazil

Background:The mild cognitive impairment(MCI)stage among elderly individuals is very complex,and the level of diagnostic accu-racy is far from *** studies have tried to improve the’MCI due to Alzheimer’s disease(AD)’classification by further stratifying these patients into ***-related symptoms may play an important role in helping to better define the MCI stage in elderly ***:In this work,we explored functional and structural differences in the brains of patients with nondepressed MCI(nDMCI)and patients with MCI with depressive symptoms(DMCI),and we examined how these groups relate to AD atrophy patterns and cognitive ***:Sixty-five participants underwent MRI exams and were divided into four groups:cognitively normal,nDMCI,DMCI,and *** compared the regional brain volumes,cortical thickness,and white matter microstructure measures using diffusion tensor imaging among ***,we evaluated changes in functional connectivity using fMRI ***:In comparison to the nDMCI group,the DMCI patients had more pronounced atrophy in the hippocampus and ***,DMCI patients had asymmetric damage in the limbic-frontal white matter ***,two medial pos-terior regions,the isthmus of cingulate gyrus and especially the lingual gyrus,had high importance in the structural and functional differentiation between the two ***:It is possible to differentiate nDMCI from DMCI patients using MRI techniques,which may contribute to a better charac-terization of subtypes of the MCI stage.

关键词： mild cognitive impairment depressive disorders Alzheimer’s Disease neuroimaging

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A Survey on Chinese Sign Language Recognition:From Traditional Methods to Artificial Intelligence

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Computer Modeling in Engineering & sciences 2024年第7期140卷 1-40页

作者： Xianwei Jiang Yanqiong Zhang Juan Lei Yudong Zhang School of Mathematics and Information Science Nanjing Normal University of Special EducationNanjing210038China School of Computing and Mathematical sciences University of LeicesterLeicesterLE17RHUK Department of Information Technology Faculty of Computing and Information TechnologyKing Abdulaziz UniversityJeddah21589Saudi Arabia

Research on Chinese Sign Language(CSL)provides convenience and support for individuals with hearing impairments to communicate and integrate into *** article reviews the relevant literature on Chinese Sign Language Recognition(CSLR)in the past 20 *** Markov Models(HMM),Support Vector Machines(SVM),and Dynamic Time Warping(DTW)were found to be the most commonly employed technologies among traditional *** from the rapid development of computer vision and artificial intelligence technology,Convolutional Neural Networks(CNN),3D-CNN,YOLO,Capsule Network(CapsNet)and various deep neural networks have sprung *** Neural Networks(DNNs)and their derived models are integral tomodern artificial intelligence *** addition,technologies thatwerewidely used in the early days have also been integrated and applied to specific hybrid models and customized identification *** language data collection includes acquiring data from data gloves,data sensors(such as Kinect,LeapMotion,etc.),and high-definition ***,facial expression recognition,complex background processing,and 3D sign language recognition have also attracted research interests among *** to the uniqueness and complexity of Chinese sign language,accuracy,robustness,real-time performance,and user independence are significant challenges for future sign language recognition ***,suitable datasets and evaluation criteria are also worth pursuing.

关键词： Chinese Sign Language Recognition deep neural networks artificial intelligence transfer learning hybrid network models

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Maize heat shock proteins-prospection,validation,categorization and in silico analysis of the different ZmHSP families

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Stress Biology 2023年第1期3卷 403-423页

作者： Rubens Diogo-Jr. Edila Vilela de Resende Von Pinho Renan Terassi Pinto Lingrui Zhang Jorge Alberto Condori-Apfata Paula Andrade Pereira Danielle Rezende Vilela Department of Horticulture and Landscape Architecture Purdue UniversityWest LafayetteIN(47907)USA Department of Agriculture Federal University of Lavras(UFLA)LavrasMG(37200-900)Brazil faculty of philosophy and sciences at ribeirao preto University of Sao Paulo(USP)Ribeirao PretoSP(14040-901)Brazil faculty of Engineering and Agricultural sciences Universidad Nacional Toribio Rodriguez de Mendoza de Amazonas(UNTRM)ChachapoyasAM(01001)Peru

Among the plant molecular mechanisms capable of effectively mitigating the effects of adverse weather conditions,the heat shock proteins(HSPs),a group of chaperones with multiple functions,stand *** a time of full progress on the omic sciences,they look very promising in the genetic engineering field,especially in order to conceive superior genotypes,potentially tolerant to abiotic stresses(AbSts).Recently,some works concerning certain families of maize HSPs(ZmHSPs)were ***,there was still a lack of a study that,with a high degree of criteria,would fully conglomerate *** distinct but complementary strategies,we have prospected as many ZmHSPs candidates as possible,gathering more than a thousand *** detailed data mining,we accounted for 182 validated ones,belonging to seven families,which were subcategorized into classes with potential for functional *** them,we identified dozens of motifs with some degree of similarity with proteins from different kingdoms,which may help explain some of their still poorly understood means of *** in silico and in vitro approaches,we compared their expression levels after controlled exposure to several AbSts’sources,applied at diverse tissues,on varied phenological *** on gene ontology concepts,we still analyzed them from different perspectives of term *** have also searched,in model plants and close species,for potentially orthologous *** all these new insights,which culminated in a plentiful supplementary material,rich in tables,we aim to constitute a fertile consultation source for those maize researchers attracted by these interesting stress proteins.

关键词： Biotechnology Genomics Corn Stress Drought Compendium

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Functional and structural changes in internal pudendal arteries underlie erectile dysfunction induced by androgen deprivation

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Asian Journal of Andrology 2017年第5期19卷 526-532页

作者： Rheure Alves-Lopes Karla B Neves Marcondes AB Silva Vania C Olivon Silvia G Ruginsk Jose Antunes-Rodrigues Leandra NZ Ramalho Rita C Tostes Fernando Silva Carneiro Department of Pharmacology Ribeirao Preto Medical School University of Sao Paulo Ribeirao Preto SP Brazil Department of Physics and Chemistry Faculty of Pharmaceutical Sciences of Ribeirao Preto University of Sao Paulo Ribeirao Preto SP Brazil Department of Physiological sciences Biomedical Sciences InstituteFederal University of Alfenas Alfenas MG Brazil Department of Physiology Ribeirao Preto Medical School University of Sao Paulo Ribeirao Preto SP Brazil Department of Pathology and Legal Medicine Ribeirao Preto Medical School University of Sao Paulo Ribeirao Preto SP Brazil

Androgen deficiency is strongly associated with erectile dysfunction （ED）. Inadequate penile arterial blood flow is one of the major causes of ED. The blood flow to the corpus cavernosum is mainly derived from the internal pudendal arteries （IPAs）; however, no study has evaluated the effects of androgen deprivation on IPA＇s function. We hypothesized that castration impairs IPAs reactivity and structure, contributing to ED. In our study, Wistar male rats, 8-week-old, were castrated and studied 30 days after orchiectomy. Functional and structural properties of rat IPAs were determined using wire and pressure myograph systems, respectively. Protein expression was determined by Western blot and immunohistochemistry. Plasma testosterone levels were determined using the IMMULITE 1000 Immunoassay System. Castrated rats exhibited impaired erectile function, represented by decreased intracavernosal pressure/mean arterial pressure ratio. IPAs from castrated rats exhibited decreased phenylephrine- and electrical field stimulation （EFS）-induced contraction and decreased acetylcholine- and EFS-induced vasodilatation. IPAs from castrated rats exhibited decreased internal diameter, external diameter, thickness of the arterial wall, and cross-sectional area. Castration decreased nNOS and α-actin expression and increased collagen expression, p38 （Thr180/ryr182） phosphorylation, as well as caspase 3 cleavage. In conclusion, androgen deficiency is associated with impairment of IPA reactivity and structure and increased apoptosis signaling markers. Our findings suggest that androgen deficiency-induced vascular dysfunction is an event involving hypotrophic vascular remodeling of IPAs.

关键词： androgen castration internal pudendal artery

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G2/M inhibitors as pharmacotherapeutic opportunities for glioblastoma:the old,the new,and the future

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Cancer Biology & Medicine 2018年第4期15卷 354-374页

作者： Angel Mauricio Castro-Gamero Julia Alejandra Pezuk Maria Sol Brassesco Luiz Gonzaga Tone Human Genetics Laboratory Institute of Natural SciencesFederal University of Alfenas(UNIFAL-MG)Alfenas 37130-001Brazil Biotechnology and Innovation in Health Program and Pharmacy Program Anhanguera University Sao Paulo(UNIANSP)Sao Paulo 05145-200Brazil Department of Biology Faculty of PhilosophySciences and Letters at Ribeirao PretoUniversity of Sao PauloRibeirao Preto 14040-901Brazil Department of Pediatrics Department of Genetics Ribeirao Preto School of MedicineUniversity of Sao PauloRibeirao Preto 14049-900Brazil

Glioblastoma(GBM) is one of the deadliest tumors and has a median survival of 3 months if left untreated. Despite advances in rationally targeted pharmacological approaches, the clinical care of GBM remains palliative in intent. Since the majority of altered signaling cascades involved in cancer establishment and progression eventually affect cell cycle progression, an alternative approach for cancer therapy is to develop innovative compounds that block the activity of crucial molecules needed by tumor cells to complete cell division. In this context, we review promising ongoing and future strategies for GBM therapeutics aimed towards G2/M inhibition such as anti-microtubule agents and targeted therapy against G2/M regulators like cyclin-dependent kinases,Aurora inhibitors, PLK1, BUB, 1, and BUBR1, and survivin. Moreover, we also include investigational agents in the preclinical and early clinical settings. Although several drugs were shown to be gliotoxic, most of them have not yet entered therapeutic trials. The use of either single exposure or a combination with novel compounds may lead to treatment alternatives for GBM patients in the near future.

关键词： Chemotherapy PLK1 AURK survivin BUB BUR1

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国际护理知识网络建设的调查研究

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International Journal of Nursing sciences 2024年第3期11卷 374-380,I0004,I0005页

作者： Margareth Santos Zanchetta Suzanne Fredericks Kateryna Metersky Geraldine Martorella Pammla Petrucka Laurie Clune Kelly Graziani Giacchero Vedana Cristina Rosa Soares Lavareda Baixinho Cristianne Maria Famer Rocha Sara Campagna Sally Zhang He Márcia Teles de Oliveira Gouveia Marcelo Medeiros Denize Bouttelet Munari Daniel Gonzalo Eslava Albarracin Carlos Aguilera-Serrano Walterlania Silva Santos Toronto Metropolitan University TorontoCanada Florida State University TallahasseeUSA University of Saskatchewan ReginaCanada University of Regina ReginaCanada State of Sao Paulo University Ribeirao PretoBrazil Lisbon Superior School of Nursing LisbonPortugal Federal University of Rio Grande do Sul Porto AlegreBrazil University of Turin TurinItaly Scarborough Health Network ScarboroughCanada Federal University of Piauí TeresinaBrazil Federal University of Goias GoianiaBrazil Fundacion Universitaria Cafam BogotaColombia University of Malaga MalagaSpain University of Brasília Ceil^andiaBrazil

本文报告了为创建护理知识网络(Nursing Knowledge Network,NKN)对不同国家护理院校进行环境扫描调查所收集到的信息。采用在线方式(2021年2-10月)进行环境扫描,探索研究领域的确定、现有资源、预期收益、教学研究创新、知识传播障碍及... 详细信息

本文报告了为创建护理知识网络(Nursing Knowledge Network,NKN)对不同国家护理院校进行环境扫描调查所收集到的信息。采用在线方式(2021年2-10月)进行环境扫描,探索研究领域的确定、现有资源、预期收益、教学研究创新、知识传播障碍及网络的预期贡献。目标信息提供者包括来自13个国家63所大学的200名护理教师。要求每所大学有1名参与者回答问卷。共有42所大学(约70%)回复,包括巴西21所,加拿大4所,葡萄牙和西班牙各3所,哥伦比亚、墨西哥、秘鲁和美国各2所,智利、意大利和巴拉圭各1所。其分享了相关信息和见解:通过护理高等教育机构之间的协作和交流,全球可以加强共同创新和研究合作能力;较少被研究的领域是知识网络生成证据、为当地科学实践提供信息的潜在重点。这些信息将为进一步了解护理发展,以及地方、区域和全球护理证据应用和传播相关的政府政策与计划制订提供参考。

关键词：信息网络创新扩散国际教育交流知识管理护理教育护理教师实践护理院校跨文化护理

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