检索结果-南通市图书馆

Effects of mesenchymal stem cell on dopaminergic neurons,motor and memory functions in animal models of Parkinson's disease:a systematic review and meta-analysis

引用

Neural Regeneration Research 2024年第7期19卷 1584-1592页

作者： Jong Mi Park Masoud Rahmati Sang Chul Lee Jae Il Shin Yong Wook Kim Department and Research Institute of Rehabilitation Medicine Yonsei University College of MedicineSeoulSouth Korea Department of Physical education and Sport sciences Faculty of Literature and Human SciencesLorestan UniversityKhoramabadIran Department of Pediatrics Yonsei University College of MedicineSeoulSouth Korea

Parkinson’s disease is chara cterized by the loss of dopaminergic neurons in the substantia nigra pars com pacta,and although restoring striatal dopamine levels may improve symptoms,no treatment can cure or reve rse the disease *** cell therapy has a regenerative effect and is being actively studied as a candidate for the treatment of Parkinson’s *** stem cells are considered a promising option due to fewer ethical concerns,a lower risk of immune rejection,and a lower risk of *** performed a meta-analysis to evaluate the therapeutic effects of mesenchymal stem cells and their derivatives on motor function,memory,and preservation of dopamine rgic neurons in a Parkinson’s disease animal *** searched bibliographic databases(PubMed/MEDLINE,Embase,CENTRAL,Scopus,and Web of Science)to identify articles and included only pee r-reviewed in vivo interve ntional animal studies published in any language through J une 28,*** study utilized the random-effect model to estimate the 95%confidence intervals(CI)of the standard mean differences(SMD)between the treatment and control *** use the systematic review center for laboratory animal expe rimentation’s risk of bias tool and the collaborative approach to meta-analysis and review of animal studies checklist for study quality assessment.A total of 33studies with data from 840 Parkinson’s disease model animals were included in the *** with mesenchymal stem cells significantly improved motor function as assessed by the amphetamine-induced rotational *** the stem cell types,the bone marrow MSCs with neurotrophic factor group showed la rgest effect size(SMD[95%CI]=-6.21[-9.50 to-2.93],P=0.0001,I^(2)=0.0%).The stem cell treatment group had significantly more tyrosine hydroxylase positive dopamine rgic neurons in the striatum([95%CI]=1.04[0.59 to 1.49],P=0.0001,I^(2)=65.1%)and substantia nigra(SMD[95%CI]=1.38[0.89 to 1.87],P=0.0001,I^(2)=75.3%),indicating a

关键词： animal animal experimentation mesenchymal stem cells models Parkinson’s disease stem cell transplantation

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Single-station microtremor surveys for site characterization:A case study in Erzurum city,eastern Turkey

引用

Earthquake Engineering and Engineering Vibration 2024年第3期23卷 563-576页

作者： Fatih Karsli Erdem Bayrak The Higher education Credit and Hostels Institution Ministry of Youth and SportsErzurum 25240Turkey Earthquake Research Centre Ataturk UniversityErzurum 25240Turkey Department of Civil Engineering Ataturk UniversityErzurum 25240Turkey

The single-station microtremor method is one of the fastest,most reliable,and cheapest methods used to identify dynamic soil *** study utilizes 49 single-station microtremor measurements to identify the dynamic soil properties of the Hilalkent quarter of the Yakutiye district in *** dominant frequency and the amplification factor were calculated by using the Nakamura horizontal/vertical spectral ratio(H/V)*** the soil dominant frequency values varied between 0.4 Hz and 10 Hz,the soil amplification factor changed between 1 and *** H/V values were acquired with lower frequency *** vulnerability index(K_(g))and shear strain parameters that are utilized to estimate the damage that may be caused by an earthquake were *** in the west side of the study area,higher K_(g) values were *** shear strain map was created with 0.25 g,0.50 g and 0.75 g bedrock accelerations,and soil types that lost elasticity during an earthquake were *** average shear wave velocity for the first 30 m(V_(s30))was ***,it was observed that the western part of the study area,which resulted in a higher period and higher H/V,higher K_(g) and lower V_(s30) values,presents a higher risk of damage during an earthquake.

关键词： Nakamura horizontal/vertical spectral ratio single-station microtremor predominant frequency vulnerability index Erzurum

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Genetic Basis for Mucormycosis Progression in COVID-19 Patients:From Susceptibility to Severity

引用

Infectious Diseases & Immunity 2024年第2期4卷 86-92页

作者： Jethendra Kumar Muruganantham Ramakrishnan Veerabathiran Human Cytogenetics and Genomics Laboratory Faculty of Allied Health SciencesChettinad Hospital and Research InstituteChettinad Academy of Research and EducationKelambakkamTamilnadu 603103India.

The dynamics of COVID-19 and mucormycosis reveal a complex interplay of genetic factors that influence the susceptibility,severity,and immune ***-19,caused by severe acute respiratory syndrome coronavirus 2(SARS-CoV-2),exhibits an increased incidence of mucormycosis,particularly in individuals with comorbidities or corticosteroid *** is a fungal infection that affects the sinuses,orbits,and lungs and demands timely intervention with antifungal medications and surgery because of its life-threatening *** on the genetic underpinnings of this intersection has unveiled key insights into the pathogenicity of *** in genetic tools have exposed virulence factors,such as the CotH protein family and high-affinity iron-uptake *** susceptibility is a pivotal element in identifying individuals at risk of developing COVID-19,facilitating early detection,and allowing for personalized treatment ***9,MIF,and TYK2 are among the genes implicated in COVID-19 severity,emphasizing the intricate relationship between genetic makeup and viral *** genetic landscape extends to viral entry mechanisms,thereby affecting infection *** polymorphisms in genes such as IFNAR2,OAS3,and TYK2 are associated with COVID-19 severity,indicating shared genetic bases between severe and hospitalized *** is genetically predisposed,particularly in immunocompromised *** challenge lies in understanding the genetic factors influencing susceptibility and offering insights into pathogenesis and potential therapeutic *** transplantation adds another layer,increasing susceptibility to infections such as COVID-19 and *** impact of immunosuppression on COVID-19 severity remains elusive,necessitating ongoing research on the immunological *** the challenges posed by emerging SARSCoV-2 variants,the intricate connection between genetic factors and the

关键词： COVID-19 Mucormycosis Pathogenesis Genetics basis

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

An Extensive Review of Vitiligo-Associated Conditions

引用

International Journal of Dermatology and Venereology 2024年第1期7卷 44-51页

作者： Madhavi Premkumar Iyshwarya Bhaskar Kalarani Vajagathali Mohammed Ramakrishnan Veerabathiran Human Cytogenetics and Genomics Laboratory Faculty of Allied Health SciencesChettinad Hospital and Research InstituteChettinad Academy of Research and EducationKelambakkamTamil Nadu 603103India

Vitiligo is an autoimmune disorder caused by the destruction of melanocytes in various body *** diseases may accompany *** prevalence of vitiligo varies among geographical regions and shows no relation to sex or ***,vitiligo most commonly affects people aged 10 to 30 *** clinical symptoms of vitiligo include irregular patches on the skin and various diseases associated with this *** present review focuses on the clinical effects and risk factors of vitiligo-associated conditions and the current therapeutics for treating *** systematic review was performed based on the PRISMA guidelines and articles published from 2000 to 2023 in Web of Science,PubMed,PsycINFO,and *** most clinically significant diseases associated with vitiligo are alopecia areata,autoimmune thyroid disease,Addison disease,and type 1 diabetes *** targeted population is specifically prone to vitiligo;it does not affect any particular race or ***,awareness of the diseases associated with vitiligo is necessary to control them through various medical and surgical treatments with the proper facilities.

关键词： vitiligo autoimmune disorder melanocyte Addison disease atopic dermatitis

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

社区居家老年人跌倒经历的体验:质性研究的meta整合

引用

International Journal of Nursing sciences 2024年第2期11卷 276-285页

作者：江慧悯袁浩斌 Stephen TEE 林爱贞 faculty of Health sciences and sports Macao Polytechnic UniversityMacaoChina faculty of Health and Social sciences Bournemouth UniversityBournemouthEnglandUK

目的系统评价和整合社区居家老年人跌倒经历的看法与体验,为后续发展跌倒预防及管理的干预提供信息,为健康照护实践提供建议。方法依据乔安娜布里格斯研究所(Joanna Briggs Institute,JBI)质性系统评价方法论进行质性研究meta整合,在Pub... 详细信息

目的系统评价和整合社区居家老年人跌倒经历的看法与体验,为后续发展跌倒预防及管理的干预提供信息,为健康照护实践提供建议。方法依据乔安娜布里格斯研究所(Joanna Briggs Institute,JBI)质性系统评价方法论进行质性研究meta整合,在PubMed、CINAHL、PsycInfo、Embase、Web of science等数据库进行检索,发表时间限定为2010年1月至2023年5月,仅纳入经同行评审的英文文献。使用JBI质性研究质量评价标准评价纳入文献的方法学质量,按照ConQual评分准则检验整合结果的信度。本综述方案已在PROSPERO注册(CRD 42023421789)。结果共纳入10项研究,方法学质量评价得分为60%至90%。提炼59个完好明确的结果,将相似结果归纳组合形成7个类别,并综合成3个整合结果,在ConQual评分上,综合结果2评为中等,综合结果1和3评为低等。整合结果1:跌倒后老年人经历了身体的损伤和疼痛、日常活动受限、社交受限、独立性降低或丧失、并有恐惧和无助感。整合结果2:经历跌倒后,老年人反思跌倒的原因,并识别、解释风险因素。整合结果3:老年人对跌倒原因和后果有正面和负面的看法,其采取的应对跌倒的措施包括使用辅助器具、纠正风险因素、寻求医疗帮助、关注身体和心理状况等。结论医疗卫生提供者应重视老年人跌倒后的感受、经历,以及对跌倒原因和影响的反思,进行特定的干预。今后还需要进行纵向研究,以检测跌倒对老年人的长期影响,深入了解他们的反思、感知、态度和预防行为随时间的改变情况。

关键词：老年人社区经历跌倒观点系统综述

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Structural regulation of coal-derived hard carbon anode for sodium-ion batteries via pre-oxidation

引用

Rare Metals 2024年第6期43卷 2585-2596页

作者： Meng-Yuan Su Kai-Yang Zhang Edison Huixiang Ang Xue-Li Zhang Yan-Ning Liu Jia-Lin Yang Zhen-Yi Gu Faaz A.Butt Xing-Long Wu faculty of Chemistry Northeast Normal UniversityChangchun 130024China MOE Key Laboratory for UV Light-Emiting Materials and Technology.Northeast Normal University.Ministry of education Changchun 130024China Natural sciences and Science education National Institute of EducationNanyang Technological UniversitySingapore 637616Singapore Materials Engineering Department NED University of Engineering and TechnologyKarachi 75300Pakistan

Hard carbon(HC)is broadly recognized as an exceptionally prospective candidate for the anodes of sodium-ion batteries(SIBs),but their practical implementation faces substantial limitations linked to precursor factors,such as reduced carbon yield and increased ***,a cost-effective approach is proposed to prepare a coal-derived HC anode with simple pre-oxidation followed by a post-carbonization process which effectively expands the d_(002)layer spacing,generates closed pores and increases defect *** these modifications,the resulting HC anode attains a delicate equilibrium between plateau capacity and sloping capacity,showcasing a remarkable reversible capacity of 306.3 mAh·g^(-1)at 0.03 A·g^(-1).Furthermore,the produ ced HC exhibits fast reaction kinetics and exceptional rate performance,achieving a capacity of 289 mAh·g^(-1)at 0.1 A·g^(-1),equivalent to~94.5%of that at 0.03 A·g^(-1).When implemented in a full cell configuration,the impressive electrochemical performance is evident,with a notable energy density of 410.6 Wh·kg^(-1)(based on cathode mass).In short,we provide a straightforward yet efficient method for regulating coal-derived HC,which is crucial for the widespread use of SIBs anodes.

关键词： Sodium-ion batteries Hard carbon Anode Coal Pre-oxidation

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Superior piezoelectric performance with high operating temperature in bismuth ferrite-based ternary ceramics

引用

Journal of Materials Science & Technology 2024年第2期169卷 172-181页

作者： Yunyao Huang Leiyang Zhang Ruiyi Jing Yang Yang Vladimir Shur Xiaoyong Wei Li Jin Electronic Materials Research Laboratory Key Laboratory of the Ministry of EducationSchool of Electronic Science and EngineeringXi’an Jiaotong UniversityXi’an 710049China faculty of Materials and Manufacturing Key Laboratory of Advanced Functional MaterialsEducation Ministry of ChinaBeijing University of TechnologyBeijing 100124China School of Natural sciences and Mathematics Ural Federal UniversityEkaterinburg620000Russia

Due to the thermal depolarization effect,adequate piezoelectric performance with high operating temperature is regarded to be challenging to accomplish concurrently in piezoceramics for applications in specific piezoelectric *** this work,we synthesized(0.8−x)BiFeO_(3)-x PbTi_(3)-0.2Ba(Zr_(0.25)Ti_(0.75))O_(3)(abbreviated as BFO-x PT-BZT)ternary solid solutions with 0.15≤x≤0.30 by conventional solid-state reaction *** MPB composition with a coexisting state of rhombohedral-tetragonal phases exhibits enhanced electromechanical properties,including Curie temperature of 380℃,large-signal equivalent piezoelectric coefficient d^(∗)_(33)of 395 pm V^(-1),small-signal piezoelectric coefficient d_(33)of 302 pC N^(-1),and electromechanical coupling factor k_(p)of 50.2%,which is comparable to commercial PZT-5A ceramics,indicating potential in high-temperature ***,in-situ X-ray diffraction(XRD)and piezoelectric force microscopic(PFM)techniques demonstrate that multiphase coexistence and complex nanodomains promote piezoelectric response via *** x=0.24 composition exhibits the highest in-situ d_(33)of 577 pC N^(-1)and good temperature stability in 30−280℃,indicating that BZT-modified BFO-PT ceramics are promising candidates for high-temperature piezoelectric devices.

关键词： High-temperature piezoelectrics Morphotropic phase boundary In-situ technique Domain structure BFO

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Image Fusion Using Wavelet Transformation and XGboost Algorithm

引用

Computers, Materials & Continua 2024年第4期79卷 801-817页

作者： Shahid Naseem Tariq Mahmood Amjad Rehman Khan Umer Farooq Samra Nawazish Faten S.Alamri Tanzila Saba Department of Information sciences Division of S&TUniversity of EducationLahore54770Pakistan Artificial Intelligence and Data Analytics(AIDA)Lab CCIS Prince Sultan UniversityRiyadh11586Saudi Arabia faculty of Information sciences University of EducationVehari CampusVehari61100Pakistan Department of Computer Science University of Engineering and TechnologyTaxila47050Pakistan Department of Mathematical sciences College of SciencePrincess Nourah Bint Abdulrahman UniversityRiyadh84428Saudi Arabia

Recently,there have been several uses for digital image *** fusion has become a prominent application in the domain of imaging *** create one final image that provesmore informative and helpful compared to the original input images,image fusion merges two or more initial images of the same *** fusion aims to produce,enhance,and transform significant elements of the source images into combined images for the sake of human visual *** fusion is commonly employed for feature extraction in smart robots,clinical imaging,audiovisual camera integration,manufacturing process monitoring,electronic circuit design,advanced device diagnostics,and intelligent assembly line robots,with image quality varying depending on *** research paper presents various methods for merging images in spatial and frequency domains,including a blend of stable and curvelet transformations,everageMax-Min,weighted principal component analysis(PCA),HIS(Hue,Intensity,Saturation),wavelet transform,discrete cosine transform(DCT),dual-tree Complex Wavelet Transform(CWT),and multiple wavelet *** fusion methods integrate data from several source images of an identical target,thereby enhancing information in an extremely efficient *** precisely,in imaging techniques,the depth of field constraint precludes images from focusing on every object,leading to the exclusion of certain *** tackle thess challanges,a very efficient multi-focus wavelet decomposition and recompositionmethod is *** use of these wavelet decomposition and recomposition techniques enables this method to make use of existing optimized wavelet code and filter *** simulated outcomes provide evidence that the suggested approach initially extracts particular characteristics from images in order to accurately reflect the level of clarity portrayed in the original *** study enhances the performance of the eXtreme Gradient Boosting(XGBoos

关键词： Image fusion max-min average CWT XGBoost DCT inclusive innovations spatial and frequency domain

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Outsmarting Android Malware with Cutting-Edge Feature Engineering and Machine Learning Techniques

引用

Computers, Materials & Continua 2024年第4期79卷 651-673页

作者： Ahsan Wajahat Jingsha He Nafei Zhu Tariq Mahmood Tanzila Saba Amjad Rehman Khan Faten S.A.lamri faculty of Information Technology Beijing University of TechnologyBeijing100124China Artificial Intelligence and Data Analytics(AIDA)Lab CCIS Prince Sultan UniversityRiyadh11586Saudi Arabia faculty of Information sciences University of EducationVehari CampusVehari61100Pakistan Department of Mathematical sciences College of SciencePrincess Nourah bint Abdulrahman UniversityRiyadh84428Saudi Arabia

The growing usage of Android smartphones has led to a significant rise in incidents of Android malware andprivacy *** escalating security concern necessitates the development of advanced technologies capableof automatically detecting andmitigatingmalicious activities in Android applications(apps).Such technologies arecrucial for safeguarding user data and maintaining the integrity of mobile devices in an increasingly digital *** methods employed to detect sensitive data leaks in Android apps are hampered by two major limitationsthey require substantial computational resources and are prone to a high frequency of false *** meansthat while attempting to identify security breaches,these methods often consume considerable processing powerand mistakenly flag benign activities as malicious,leading to inefficiencies and reduced reliability in *** proposed approach includes a data preprocessing step that removes duplicate samples,managesunbalanced datasets,corrects inconsistencies,and imputes missing values to ensure data *** Minimaxmethod is then used to normalize numerical data,followed by feature vector extraction using the Gain ratio andChi-squared test to identify and extract the most significant characteristics using an appropriate prediction *** study focuses on extracting a subset of attributes best suited for the task and recommending a predictivemodel based on domain expert *** proposed method is evaluated using Drebin and TUANDROMDdatasets containing 15,036 and 4,464 benign and malicious samples,*** empirical result shows thatthe RandomForest(RF)and Support VectorMachine(SVC)classifiers achieved impressive accuracy rates of 98.9%and 98.8%,respectively,in detecting unknown Androidmalware.A sensitivity analysis experiment was also carriedout on all three ML-based classifiers based on MAE,MSE,R2,and sensitivity parameters,resulting in a flawlessperformance for both *** app

关键词： Android malware detection machine learning SVC K-Nearest Neighbors(KNN) RF

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Relationships among Sedentary Time,Electronic Product Addiction,and Depression in Adolescents during the COVID-19 Epidemic:A Cross-Lagged Study

引用

International Journal of Mental Health Promotion 2024年第3期26卷 221-228页

作者： Feng Sheng Chen Kong Chao Li Teaching Department of sports Qufu Normal UniversityQufu273165China Teaching Department of sports Shandong Management UniversityJinan250100China General education Center Weifang Vocational CollegeWeifang262737China

Objective:This study was conducted to explore the relationships among sedentary behavior(SB),electronic product addiction(EPA),and depression(D)in adolescents during the COVID-19 ***:A total of 604 adolescents(including 309 girls and 295 boys aged 12-18)were selected from Qufu City,Shandong Province,China for three rounds of *** model was constructed using AMOS 23.0 software,and cross-lagged analysis was ***:SB at T1 can significantly positively predict SB and EPA at T2(p<0.05).EPA at T1 can significantly positively predict SB and D at T2(p<0.05).Physical activity level and SB at T2 can significantly predict SB and EPA at T3(p<0.05).EPA at T2 can significantly predict SB,EPA,and D at T3(p<0.05).Conclusions:SB and EPA are predictive factors for ***,SB can significantly positively predict D and indirectly predict D through the mediating effect of EPA.

关键词： COVID-19 electronic product addiction depression sedentary behavior

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：