检索结果-南通市图书馆

Spatial and temporal patterns of forest fires in the Central Monte:relationships with regional climate

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Ecological Processes 2024年第1期13卷 66-79页

作者： Pablo Eugenio Villagra Erica Cesca Leandro Manuel Alvarez Silvia delgado Ricardo Villalba Instituto Argentino de Nivología Glaciología y ciencias Ambientales–CONICET-CCT Mendoza facultad de ciencias Agrarias Universidad Nacional de Cuyo

Background Natural and anthropogenic wildfires burn large areas of arid and semi-arid forests with significant socio-economic and environmental impacts. fire regimes are controlled by climate, vegetation type, and anthropogenic factors such as ignition sources and human-induced disturbances. Projections of climate and land-use change suggest that these controlling factors will change, altering fire regimes in the near future. In the southern Central Monte, Mendoza, Argentina, the factors that modulate the fire temporal and spatial variability are poorly understood. We reconstructed the fire history of southeast of Mendoza from 1984 to 2023 and investigated the relationships between fire extent and climate variability at seasonal and interannual scales. Burned areas were determined using Google Earth Engine by processing Landsat 5-TM, Landsat 7-ETM+, and Landsat 8-OLI-TIRS sensor *** The region exhibited high spatial and temporal variability in fire occurrence, being a mosaic of areas with different fire histories and recovery times. Between 1985 and 2023, fire recurrence ranged from sites unburned to sites with up to 14 fires. The occurrence of large fires was strongly favored by a combination of a year with abundant spring–early summer precipitation, which favors fuel accumulation, followed by a year of low spring–early summer precipitation. Precipitation and burnt area showed a very pronounced 6–7 year cycle, suggesting a dominant climatic control on fire *** fire distribution in southeastern Mendoza forests is not homogeneous, resulting in a mosaic of patches with different fire histories. This heterogeneity may be related to vegetation patterns and land use. The temporal variability of fires is strongly influenced by climate variability, which would promote fuel production and subsequent drying. Large fires are concentrated in periods of high interannual precipitation variability. Climate change scenarios predict an increase in tem

关键词： fire recurrence fire mapping Recovery time Climate Dry forest Wildfire

Interpolation of closed ideals of bilinear operators

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Acta Mathematica Sinica,English Series 2024年

作者： fernando COBOS Luz M.fERNáNdeZ-CABRERA Antón MARTíNEZ departamento de Análisis matemático y matemática Aplicada Facultad de MatemáticasUniversidad Complutense de Madrid Sección departamental del departamento de Análisis matemático y matemática Aplicada Facultad de Estudios EstadísticosUniversidad Complutense de Madrid departamento de matemática Aplicada I Escuela de Ingeniería IndustrialUniversidad de Vigo

AbstractWe extend the （outer） measureγIassociated to an operator ideal I to a measureγJfor bounded bilinear *** I is surjective and closed,and J is the class of those bilinear operators such thatγJ（T）=0,we prove that J coincides with the composition bideal I o *** I satisfies the ∑r-condition,we establish a simple necessary and sufficient condition for an interpolated operator by the real method to belong to ***,if in addition I is symmetric,we prove a formula for the measureγJof an operator interpolated by the real *** particular,results apply to weakly compact operators.

关键词：

Rheological properties and concentration evolution of thickened tailings under the coupling effect of compression and shear

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

International Journal of Minerals,Metallurgy and Materials 2024年第5期31卷 862-876页

作者： Aixiang Wu Zhenqi Wang Zhuen Ruan Raimund Bürger Shaoyong Wang Yi Mo Key Laboratory of the Ministry of Education of China for High-efficient Mining and Safety of Metal Mines University of Science and Technology BeijingBeijing 100083China Shunde Innovation School University of Science and Technology BeijingFoshan 528399China CI2MA and departamento de Ingeniería matemática Facultad de Ciencias Físicas y MatemáticasUniversidad de ConcepciónCasilla 160-CConcepciónChile School of Civil and Resource Engineering University of Science and Technology BeijingBeijing 100083China China Railway Construction Tongguan Investment Co. Ltd.Tongling 244000China

Cemented paste backfill(CPB)is a key technology for green mining in metal mines,in which tailings thickening comprises the primary link of CPB ***,difficult flocculation and substandard concentrations of thickened tailings often *** rheological properties and concentration evolution in the thickened tailings remain ***,traditional indoor thickening experiments have yet to quantitatively characterize their rheological *** experiment of flocculation condition optimization based on the Box-Behnken design(BBD)was performed in the study,and the two response values were investigated:concentration and the mean weighted chord length(MWCL)of ***,optimal flocculation conditions were *** addition,the rheological properties and concentration evolution of different flocculant dosages and ultrafine tailing contents under shear,compression,and compression-shear coupling experimental conditions were tested and *** results show that the shear yield stress under compression and compression-shear coupling increases with the growth of compressive yield stress,while the shear yield stress increases slightly under *** order of shear yield stress from low to high under different thickening conditions is shear,compression,and compression-shear *** compression and compression-shear coupling,the concentration first rapidly increases with the growth of compressive yield stress and then slowly increases,while concentration increases slightly under *** order of concentration from low to high under different thickening conditions is shear,compression,and compression-shear ***,the evolution mechanism of the flocs and drainage channels during the thickening of the thickened tailings under different experimental conditions was revealed.

关键词： thickened tailings compression-shear coupling compressive yield stress shear yield stress concentration

维普期刊数据库

Monoclonal antibodies and aptamers:The future therapeutics for Alzheimer’s disease

在线全文

学校读者我要写书评

暂无评论

Acta Pharmaceutica Sinica B 2024年第7期14卷 2795-2814页

作者： Alvaro Barrera-Ocampo facultad de Ingenierıa Diseno y Ciencias AplicadasDepartamento de Ciencias Farmaceuticas y QuimicasGrupo NaturaUniversidad IcesiCali 760031Colombia

Alzheimer’s disease(AD)is considered the most common and prevalent form of dementia of adult-onset with characteristic progressive impairment in cognition and *** cure for AD has not been found yet and the treatments available until recently were only *** of multidisciplinary approaches and efforts made by pharmaceutical companies,it was only in the past two years that new drugs were approved for the treatment of the *** beta(Aβ)immunotherapy is at the core of this therapy,which is one of the most innovative approaches looking to change the course of *** technology is based on synthetic peptides or monoclonal antibodies(mAb)to reduce Ab levels in the brain and slow down the advance of ***,this article reviews the state of the art about AD neuropathogenesis,the traditional pharmacologic treatment,as well as the modern active and passive immunization describing approved drugs,and drug prototypes currently under investigation in different clinical *** addition,future perspectives on immunotherapeutic strategies for AD and the rise of the aptamer technology as a non-immunogenic alternative to curb the disease progression are discussed.

关键词： Aβ Monoclonal antibody DNA aptamers Cognitive impairment Alzheimer’s disease Clinical trials Immunotherapy Machine learning

Sex-dependent resilience to extreme drought events: implications for climate change adaptation of a South American endangered tree species

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Ecological Processes 2024年第2期13卷 48-60页

作者： Sergio Piraino Martín Ariel Hadad Yanina Antonia Ribas-fernández fidel Alejandro Roig Laboratorio de dendrocronología e Historia Ambiental (IANIGLA CONICET ) facultad de ciencias Agrarias Universidad Nacional de Cuyo Laboratorio de dendrocronología de Zonas áridas (CIGEOBIO CONICET ) Gabinete de Geología Ambiental (INGEO UNSJ) Hémera Centro de Observación de la Tierra Facultad de Ciencias Universidad Mayor

Background Recent changes in climatic trends are resulting in an increased frequency and intensity of extreme events, with unknown effect on ecosystem dynamics in the near future. Extreme drought episodes are recognized as disturbance factors capable of modifying forest dynamics and tree growth. Within this context, dioecious tree species may be impacted by climatic extremes, affecting male/female proportions and, consequently, reproductive processes and species persistence. Therefore, there is an urgent need for species-specific assessments of growth tolerance to extreme dry spells in dioecious tree species, to establish effective conservation strategies for these particular natural resources. Araucaria araucana(araucaria), an endangered dioecious Patagonian tree species, has recently undergone decay and mortality episodes in response to increasing dry climatic conditions. While sex-dependent tolerance to extreme drought episodes has been assessed in the species' humid distribution range, there is still a lack of information on the gender-based resilience of trees growing in the drier environments of the species' *** We reconstructed, through dendrochronological methods, the sex-dependent response of 105 araucaria individuals(55 female and 50 male trees) to five regional extreme dry spells employing a set of different indices. Resistance, recovery period, and average growth reduction of standardized tree-ring growth were examined, analysing the effect of biotic(sex, pre-drought stem tree growth) and abiotic(local climatic conditions before, during, and after extreme climatic episodes) factors on tree *** Sex influences only the species resistance to climatic disturbance, with male individuals showing lower tolerance to extreme drought events. Pre-drought radial growth rates and local meteorological conditions preceding, during, and following extreme dry spells strongly modulated araucaria radial growth resilience regardless of tree s

关键词： Araucaria Climate change dendrochronology Extreme drought event Resilience

Genetic and epigenetic targets of natural dietary compounds as anti-Alzheimer's agents

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Neural Regeneration Research 2024年第4期19卷 846-854页

作者： Willian Orlando Castillo-Ordoñez Nohelia Cajas-Salazar Mayra Alejandra Velasco-Reyes facultad de ciencias Naturales-Exactas y de la Educación Departamento de Biología.Universidad del Cauca departamento de Estudios Psicológicos Universidad Icesi

Alzheimer’s disease is a progressive neurodegenerative disorder and the most common cause of dementia that principally affects older *** factors,such as oxidative stress,an increase in acetylcholinesterase activity,mitochondrial dysfunction,genotoxicity,and neuroinflammation are present in this syndrome,which leads to *** pathologies such as Alzheimer’s disease are considered late-onset diseases caused by the complex combination of genetic,epigenetic,and environmental *** are two main types of Alzheimer’s disease,known as familial Alzheimer’s disease(onsetfamilial Alzheimer’s disease inherit the disease due to rare mutations on the amyloid precursor protein(APP),presenilin 1 and 2(PSEN1 and PSEN2)genes in an autosomaldominantly fashion with closely 100%*** contrast,a different picture seems to emerge for sporadic Alzheimer’s disease,which exhibits numerous non-Mendelian anomalies suggesting an epigenetic component in its ***,the fundamental pathophysiological mechanisms driving Alzheimer’s disease are interfaced with epigenetic ***,the dynamic nature of epigenetics seems to open up new avenues and hope in regenerative neurogenesis to improve brain repair in Alzheimer’s disease or following injury or stroke in *** recent years,there has been an increase in interest in using natural products for the treatment of neurodegenerative illnesses such as Alzheimer’s *** epigenetic mechanisms,such as DNA methylation,non-coding RNAs,histone modification,and chromatin conformation regulation,natural compounds appear to exert neuroprotective *** we do not purport to cover every in this work,we do attempt to illustrate how various phytochemical compounds regulate the epigenetic effects of a few Alzheimer’s disease-related genes.

关键词： Alzheimer’s disease epigenetics genes methylation natural products

维普期刊数据库

Common interacting genetic variation shapes susceptibility to type 1 diabetes in a Colombian Caribbean community:In search of shared genetic markers

在线全文

学校读者我要写书评

暂无评论

Genes & Diseases 2024年第4期11卷 106-108页

作者： Gloria Garavito-de Egea Alex Dominguez-Vargas Jorg e l.Velez Gustavo Aroca Luis fagng Elkin Navarro-Quiroz Zilac Espitaleta Kenny del Toro-Camargo Leticia Martinez-Ariza Tatiana Gonzalez-Vargas Susana Garcia Mauricio Arcos-Burgos Eduardo Egea Universidad del Norte Division Ciencias de la SaludBarranquillaColombia Universidad Simon Bolivar Facultad de Ciencias de la SaludBarranquillaColombia Clinica de la Costa Grupo de Investigacion en NefrologiaBarranquillaColombia Universidad de Antioquia Grupo de Investigacion en Psiquiatria(GIPSI)Departamento de PsiquiatriaInstituto de Investigaciones MedicasFacultad de MedicinaMedellinColombia

Genome-wide association studies(GWASs)have identified hundreds of loci across the human genome conferring susceptibility to autoimmune diseases(AIDs),some of which are shared between more than two ***,this univariate ... 详细信息

关键词： susceptibility diseases diabetes

Role of lipids in the control of autophagy and primary cilium signaling in neurons

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Neural Regeneration Research 2024年第2期19卷 264-271页

作者： María Paz Hernández-Cáceres Daniela Pinto-Nuñez Patricia Rivera Paulina Burgos francisco Díaz-Castro Alfredo Criollo Maria Jose Yañez Eugenia Morselli Instituto de Investigación en ciencias Odontológicas(ICOD) Facultad de OdontologíaUniversidad de ChileSantiagoChile department of Basic Sciences Faculty of Medicine and ScienceUniversidad San SebastiánSantiagoChile Physiology department Faculty of Biological SciencesPontificia Universidad Católica de ChileSantiagoChile Advanced Center for Chronic Diseases(ACCDiS) Facultad de Ciencias Químicas y Farmacéuticas&Facultad de MedicinaUniversidad de ChileSantiagoChile Autophagy Research Center SantiagoChile

The brain is,after the adipose tissue,the organ with the greatest amount of lipids and diversity in their composition in the human *** neurons,lipids are involved in signaling pathways controlling autophagy,a lysosome-dependent catabolic process essential for the maintenance of neuronal homeostasis and the function of the primary cilium,a cellular antenna that acts as a communication hub that transfers extracellular signals into intracellular responses required for neurogenesis and brain development.A crosstalk between primary cilia and autophagy has been established;however,its role in the control of neuronal activity and homeostasis is barely *** this review,we briefly discuss the current knowledge regarding the role of autophagy and the primary cilium in *** we review the recent literature about specific lipid subclasses in the regulation of autophagy,in the control of primary cilium structure and its dependent cellular signaling in physiological and pathological conditions,specifically focusing on neurons,an area of research that could have major implications in neurodevelopment,energy homeostasis,and neurodegeneration.

关键词： autophagic flux cholesterol fatty acids GPCR lysosomal storage diseases neurons NPC1 phosphoinositides primary cilium

维普期刊数据库

A multi-shot target wheel assembly for high-repetition-rate, laser-driven proton acceleration

在线全文

学校读者我要写书评

暂无评论

High Power Laser Science and Engineering 2024年第2期 91-98页

作者： J.Pe?as A.Bembibre D.Cortina-Gil L.Martín A.Reija C.Ruiz M.Seimetz A.Alejo J.Benlliure Instituto Galego de física de Altas Enerxías Universidade de Santiago de Compostela Laboratorio Láser de Aceleración y Aplicaciones RIAIDT Universidade de Santiago de Compostela Instituto Universitario de física fundamental y matemáticas y Dpto.de Didáctica de la matemática y de las ciencias Experimentales Universidad de Salamanca Instituto de Instrumentación para Imagen Molecular (I3M) CSIC-Universitat Politècnica de València

A multi-shot target assembly and automatic alignment procedure for laser–plasma proton acceleration at high repetition rate are introduced. The assembly is based on a multi-target rotating wheel capable of hosting more than 5000 targets,mounted on a 3D motorized stage to allow rapid replenishment and alignment of the target material between laser irradiations. The automatic alignment procedure consists of a detailed mapping of the impact positions at the target surface prior to the irradiation that ensures stable operation of the target, which alongside the purpose-built design of the target wheel, enables operation at rates up to 10 Hz. Stable and continuous laser-driven proton acceleration at 10 Hz is demonstrated, with observed cut-off energy stability about 15%.

关键词：