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Anti-inflammatory and analgesic activities with gastroprotective effect of semi-purified fractions and isolation of pure compounds from mediterranean gorgonian Eunicella singularis

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Asian Pacific Journal of Tropical medicine 2015年第8期8卷 598-603页

作者： monia deghrigue Carmen Festa Lotfi Ghribi maria Valeria D’Auria Simona de marino Hichem Ben Jannet Abderrahman Bouraoui Laboratoire de développement chimique galénique et pharmacologique des médicaments (LR12ES09).Equipe de Pharmacologie marineFaculté de pharmacie de MonastirUniversité de Monastir department of Pharmacy University of Naples "Federico II" Laboratoire de chimie hétérocyclique produits naturels et réactivité. Equipe de chimie médicinale et produits naturels (LR11ES39)Faculté des sciences de MonastirUniversité de Monastir Laboratoire de chimie hétérocyclique produits naturels et réactivité.Equipe de chimie médicinale et produits naturels (LR11ES39)Faculté des sciences de MonastirUniversité de Monastir

Objective: To explore anti-inflammatory activities of organic extract and its semi-purified fractions(ethanol, acetone, methanol/dichloromethane) from the mediterranean gorgonian Eunicella singularis. methods: The anti-inflammatory and analgesic activities were evaluated, using the carrageenan-induced rat paw edema model and the acetic acid writhing test in mice. The gastroprotective activity was determined using HCl/et OH induced gastric ulcers in rats. The purification and structure elucidation of compound(s) from the more effective fraction were determined by chromatographic and spectroscopic methods and in comparison with data reported in the literature. Results: The fraction F-et OH showed an important antiinflammatory activity associated with significant analgesic and gastroprotective properties. The purification and structure elucidation of compound(s) from this fraction lead to the identification of one diterpenoid and four sterols. Conclusions: These results suggested that components from the active fraction can be used to treat various anti-inflammatory diseases.

关键词： Eunicella singularis Anti-inflammatory activity Analgesic activity Gastroprotective effect Diterpenoid Sterols

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Complexity Analysis of an Interior Point Algorithm for the Semidefinite Optimization Based on a Kernel Function with a Double Barrier Term

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Acta mathematica Sinica,English Series 2015年第3期31卷 543-556页

作者： mohamed ACHACHE Laboratoire de mathématiques Fondamentales et Numériques Faculté des Sciences Université Ferhat Abbas Sétif 1Algérie

In this paper, we establish the polynomial complexity of a primal-dual path-following interior point algorithm for solving semidefinite optimization（SDO） problems. The proposed algorithm is based on a new kernel function which differs from the existing kernel functions in which it has a double barrier term. With this function we define a new search direction and also a new proximity function for analyzing its complexity. We show that if q1 〉 q2 〉 1, the algorithm has O（（q1 ＋ 1） nq1＋1/2（q1-q2）logn/ε）and O（（q1 ＋ 1）2（q1-q2）^3q1-2q2＋1√n logn/c） complexity results for large- and small-update methods, respectively.

关键词： Semidefinite optimization kernel functions primal-dual interior point methods large andsmall-update algorithms complexity of algorithms

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Generalized Besov Type Spaces on the Dual of the Laguerre Hypergroup

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Acta mathematica Sinica,English Series 2009年第9期25卷 1543-1560页

作者： miloud ASSAL Département de mathématiques Faculté des Sciences de Bizerte Jarzouna - Bizerte - 7021

In this paper we introduce the homogeneous Besov type spaces ∧p,q^γ（K） on the dual of Laguerre hypergroup K and we establish some new harmonic analysis results. We give some character- izations of these spaces using equivalent seminorms. Also we study the non-homogeneous Besov type spaces ∧p,q^γ（K）. We give some properties of these spaces and embeddings results with respect to their parameters p, q and γ.

关键词： Laguerre hypergroup Besov type spaces Calderón-reproducing formula

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Impact of the Inlet Flow Angle and Outlet Placement on the Indoor Air Quality

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Fluid Dynamics & materials Processing 2024年第11期20卷 2603-2616页

作者： Ikram mostefa Tounsi mustapha Boussoufi Amina Sabeur mohammed El Ganaoui Laboratoire des sciences et Ingénierie maritimes Facultéde Génie Mécanique.Universitédes Sciences et de la Technologie d’Oran Mohammed BoudiafBP 1505 El M’NaouerOran31000Algérie Laboratoire LERmAB IUT Longwy Universitéde LorraineNancy54000France

This study aims to optimize the influence of the inlet inclination angle on the Indoor Air Quality(IAQ),heat,and temperature distribution in mixed convection within a two-dimensional square cavityfilled with an air-CO_(2)*** air-CO_(2)mixture enters the cavity through two inlet openings positioned at the top wall,which is set at the ambient temperature(TC).Three values of the Reynolds numbers,ranging from 1000 to 2000,are considered,while the Prandtl number is kept constant(Pr=0.71).The temperature distribution and streamlines are shown for Rayleigh number(Ra)equal to 104,three inlet inclination anglesϕ(0,π/6 andπ/4)and three CO_(2)concentrations values(1500,2500,3500 ppm)applied at both hot vertical walls(maintained at a constant temperature TH).Afinite volume method is used under the assumption of two-dimensional laminarflow to solve the NavierStokes and energy *** results indicate that inlet inclination angle has an impact on the indoor air quality(IAQ),which,in turn,affects the heat transfer distribution and thermal comfort within the cavity.

关键词： mixed convection air-CO_(2) mixture inlet inclination angles laminarflow indoor air quality

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Purification and Characterization of Cytosolic Glyceraldehyde-3-phosphate dehydrogenase from the Dromedary Camel

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Acta Biochimica et Biophysica Sinica 2007年第2期39卷 148-154页

作者： Latifa FOURRAT,Abdelghani IDDAR,Abdelaziz SOUKRI 1Laboratoire de Physiologie et Génétique moléculaire Département de Biologie facultédes sciences A■n-Chock UniversitéHassan-Ⅱ. Casablanca morocco ~2Centre National de l'Energie des sciences et des Techniques Nucléaires Center d'etudes Nucléaires de la ma■mora Rabat 10001 morocco

Glyceraldehyde-3-phosphate dehydrogenase （GAPDH）（EC 1.***.1.12）,a key enzyme ofcarbon metabolism,was purified and characterized to homogeneity from skeletal muscle of *** protein was purified approximately 26.8 folds by conventional ammonium sulphatefractionation followed by Blue Sepharose CL-6B chromatography,and its physical and kinetic propertieswere *** native protein is a homotetramer with an apparent molecular weight of approximately146 *** focusing analysis showed the presence of only one GAPDH isoform with an isoelectricpoint of *** optimum pH of the purified enzyme was *** on the effect of temperature onenzyme activity revealed an optimal value of approximately 28-32 ℃ with activation energy of 4.9 kcal/*** apparent Kmvalues for NAD+and DL-glyceraldehyde-3-phophate were estimated to be 0.025±0.040mm and 0.21±0.08 mm, respectively. The Vmaxof the purified protein was estimated to be 52.7±5.9 U/*** kinetic parameter values were different from those described previously, reflecting protein differencesbetween species.

关键词： Camelus dromedarius glyceraldehyde-3-phosphate dehydrogenase protein purification skeletal muscle

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Numerical Study of Greenhouse Nocturnal Heat Losses

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Journal of Thermal Science 2011年第4期20卷 377-384页

作者： F.Berroug E.K.Lakhal m.El Omari m.Faraji H.El Qarnia Laboratoire d'Automatique de l'Environnement et Procédés de Transfert UniversitéCadi AyyadFacultédes Sciences Semlalia-Département de PhysiqueMarrakech-MarocAffiliéau CNRSTURAC 28 Laboratoire de Physique des materiaux MicroelectroniqueAutomatique et TechniqueDepartement de PhysiquesFaculte des Sciences Ain ChockUniversite Hassan IICasablanca-Maroc

In this study we quantify and analyze different components of nocturnal losses from a heated greenhouse with the presence of vegetation for typical winter weather conditions in marrakesh-morocco,using a non linear model,based on the greenhouse heat and mass *** was found that 12% of the total input heat was dissipate as a sensible and latent leakage losses,66% was lost by convective exchange through air-inner *** gain of energy at the inner-cover is dissipated at the outer-cover by radiation(66%)and convection(34%).This results point toward some practical measures to reduce heat losses:increasing air tightness,using covering materials with low-emissivity in the long wave band or putting up an external thermal curtain should provide significant energy savings.

关键词： Greenhouse energy balance heat losses numerical analysis.

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Preservation of Juniperus thurifera L.:a rare endangered species in Algeria through in vitro regeneration

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Journal of Forestry Research 2019年第1期30卷 77-86页

作者： Nadia Khater Halima Benbouza faculté SNV Université Batna 2 Institut des sciences Vétérinaires et sciences Agronomiques Université Batna 1 Centre de Recherche en Biotechnologies

Juniperus thurifera *** an endemic Cupres saceae from the Aure`s mountains of north eastern Algeria and endangered,in part,due to the scarcity of viable seeds It is threatened by other abiotic factors and the lack of an effective management strategy will increase its risk o *** dearth of information on its in vitro regeneration impedes its application in forest managemen *** therefore developed a micropropagation protocol using microcuttings with auxiliary *** were grown on different combinations of media supplemented with plant growth regulators at different *** highest number of shoots and branches regenerated from original shoots was obtained on Woody Plant medium(WPm)supplemented with 6-benzylaminopurine(BAP)(0.5 mg L^(-1))and 2,4-dichlorophe noxyacetic acid(2,4-D)(0.25 mg L^(-1)).The best elongation of shoots was achieved with WPm supplemented with0.5 mg L^(-1)of BAP and 0.25 or 1 mg L^(-1) of 2,*** the second subculture,shoots had a higher number of branches than those of the *** highest rooting rate,38.8%,was obtained with shoots cultured in 1/2 murashige and Skoog(mS)medium supplemented with 5.0 mg L^(-1)each of indol-3-butyric(IBA)and naphthalene acetic acid(NAA).Similarly,the highest root numbers and lengths were produced on 1/2 mS medium supplemented with IBA and NAA(5.0 mg L^(-1)each).During transfer to acclimatization,rates of plant losses of 50% *** second part of the experiment showed that the best shoot callusing was on WPm supplemented with BAP and 2,4-D,with either the combination 0.5+0.25 or 0.25+0.25 mg L^(-1).The results of this research provide a starting point for further studies on in vitro regeneration of *** for the sustainable management of its unique ecosystem in the mediterranean basin.

关键词： Juniperus thurifera Callus Conservation Regeneration In vitro culture

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Numerical Study of Classical and Composite Solar Walls by TRNSYS

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Journal of Thermal Science 2007年第1期16卷 46-55页

作者： Jibao SHEN Stéphane LASSUE Laurent ZALEWSKI dezhong HUANG School of Engineering Shaoxing College of Arts and Sciences Shaoxing University Zhejiang 312000 China Laboratoire d＇Artois de méThermique et Instrumentation （LAmTI） Faculté des Sciences Appliquées Univeristé d＇Artois 62400 Béthune France

The laboratory LAmTI has worked for several years on the study and the optimization of the thermal performances of passive solar walls like solar Trombe wall. These components of the buildings envelope have very complex behaviour because they are the seat of various coupled heat transfers modes and are subjected to the random variations of the meteorological parameters. Using the finite difference method （FDm） and starting from experimental results recorded during several years, a simulation model was developed and validated concerning the ＂composite＂ Trombe wall. In order to make this work more accessible to the community of the heat engineers, it appears interesting to build a simulation model which can be integrated into the library of elements of the TRNSYS software. A ＂Type＂ was thus carried out and the results obtained compared with those of the FDm model. In this work we compare the obtained results with these two numerical ways. The assumptions and the results of simulations are also confronted with those of an existing module in TRNSYS （Type 36） established for the ＂classical＂ Trombe wall. The study shows that the models that we developed are very precise and that certain assumptions must be used with a lot of precautions. The advantages of the composite Trombe solar wall compared to the Classical Trombe wall are highlighted for cold and/or cloudy climates.

关键词： Trombe wall solar wall classical wall composite wall finite difference method TRNSYS

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Effect of Water Quality on Heavy metal Redistribution and mobility in Polluted Agricultural Soils in a Semi-Arid Region

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Pedosphere 2019年第6期29卷 730-739页

作者： Rim AZOUZI Abdelkrim CHAREF Lamia AYED Samia KHADHAR Laboratoire Géoressources Centre des Recherches et Technologies des EauxSoliman 8020(Tunisia) Laboratoire d’Analyse Traitement et Valorisation des Polluants de l’Environnement et des ProduitsFacultéde PharmacieRue AvicenneMonastir 5000(Tunisia)

mornag Plain is a coastal area of the mediterranean basin, which has undergone an agricultural industrial boom. The aim of this study was to investigate the different water qualities used for irrigation on heavy metal mobility in these polluted agricultural soils. The geo-accumulation indices for heavy metals (Ni, Cr, Pb, Cd, Cu, and Zn) revealed that industrial activities and used treated wastewater (TWW) contributed to soil pollution, and water irrigation always decreased this contamination. After long-term use of different water types, high perturbation of heavy metal redistribution has occurred. Groundwater use altered all heavy metal redistributions in the irrigated soil among various soil-solid and soil-solution fractions, as compared to the unirrigated soil. Slight acid water use transferred some metals from different solid phase components into water-soluble and exchangeable fractions. However, TWW use transformed some Ni, Cr, Cd, Cu, and Zn from water-soluble and exchangeable fractions to less labile fractions, particularly into organically bound fractions. Reuse of conventional water within the same soil decreased the whole soil redistribution index values, indicating tendency to return to the pattern of distribution of groundwater-irrigated soil.

关键词： Exchangeable fraction Geo-accumulation index Labile fraction mobility factor Organically bound fraction Redistribution index Treated wastewater Water-soluble fraction

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moderating Effect of Perceived Threat of Breast Cancer on Relation between Knowledge and Breast Self Examination

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Psycho-Oncologie 2024年第1期18卷 59-68页

作者： Carolle Annie Njopvoui Armel Valdin Teague Tsopgny Henri Rodrigue Njengoue Ngamaleu facultédes sciences de l'Éducation Universitéde YaoundéYaoundéCameroun

Estimated at more than 2.2 million cases worldwide,most breast cancer cases and deaths from breast cancer occur in low and middle-income *** Cameroon,many studies have underlined the effect of knowledge of breast cancer on screening measures such as self-examination and,to a lesser extent,the perception of the threat of this *** research aims to assess according to the Health Belief model(HBm),the moderating effect of perceived threat of breast cancer on the relation between knowledge and breast self-examination.A questionnaire survey was conducted among 517 Cameroonian women to assess their general knowledge about breast cancer(risk factors and screening measures),their level of the perceived threat of breast cancer through Perceived susceptibility and severity,and the prevalence of breast self-examination amongst them.A regression analysis using the macro Process for moderation indicates the main effect of Perceived threat(b=0,29;t(517)=2,36;p=0,02)of breast cancer and knowledge(b=0,02;t(517)=4,29;pm that the perceived threat of breast cancer moderates the effect of knowledge on breast *** the low level of perceived threat highlights the effect of knowledge on breast self-examination(b=0,02;t(517)=3,49;pman who perceives severity and susceptibility to breast cancer is more inclined to perform breast *** result suggests the importance of taking into account,in a context where knowledge of breast cancer is limited,relevant factors of the health belief model in preventive measures against breast cancer in general and the practice of breast self-examination in particular.

关键词： Knowledge perceived threat breast cancer breast self-examination moderation effect HBm

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