In this paper we review some results obtained within the context of the predictive microbiology, which is a specific field of the population dynamics. In particular we discuss three models, which exploit tools of stat...
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In this paper we review some results obtained within the context of the predictive microbiology, which is a specific field of the population dynamics. In particular we discuss three models, which exploit tools of statistical mechanics, for bacterial dynamics in food of animal origin. In the first model, the random fluctuating behaviour, experimentally measured, of the temperature is considered. In the second model stochastic differential equations are introduced to take into account the influence of physical and chemical variables, such as temperature, pH and activity water, subject to deterministic and random variations. The third model, which is an extended version of the second one, neglects the environmental fluctuations, and concentrates on the role of the interspecific bacterial interactions. The comparison between expected results and observed data indicates that the presence of noise sources and interspecific bacterial interactions improves the predictive features of the models analyzed.
The progress of research in nucleic acid immunization promises new avenues to many infectious disease prophylaxis and therapeutics in human and animals. The commercialization and licensing of DNA vaccines are subjecte...
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The progress of research in nucleic acid immunization promises new avenues to many infectious disease prophylaxis and therapeutics in human and animals. The commercialization and licensing of DNA vaccines are subjected to similar if not more stringent regulatory and market conditions as in many conventional vaccines in terms of administration regimen and dose presentation. The efficacy of a rabies DNA vaccine containing a plasmid encoding for the rabies virus glycoprotein gene was evaluated in dogs in a single-dose regimen. The extended duration of immunity of the vaccine was demonstrated by challenge with a wild type virus 17 months post vaccination. Similarly, conventional equine West Nile Virus vaccines are available in the United States as a monovalent as well as multivalent combination vaccines containing a number of other viral antigens.
The authors regret publishing the incorrect address and *** have been now revised as follows:*** Addresses are updated from.“a School of Traditional Chinese Medicine,Shenyang Pharmaceutical University,Shenyang,110016...
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The authors regret publishing the incorrect address and *** have been now revised as follows:*** Addresses are updated from.“a School of Traditional Chinese Medicine,Shenyang Pharmaceutical University,Shenyang,110016,PR China b State Key Laboratory of Toxicology and Medical Countermeasures,Beijing Institute of Pharmacology and Toxicology,Beijing,100850,PR China c School of Functional Food and Wine,Shenyang Pharmaceutical University,Shenyang,10016,PR China.
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