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Production of medical radioisotope ^(64)Cu by photoneutron reaction using ELI-NP γ-ray beam

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nuclear Science and Techniques 2016年第4期27卷 147-151页

作者： Wen Luo School of nuclear Science and Technology University of South China extreme light infrastructure - nuclear physics (ELI-NP)/‘‘Horia Hulubei’’ National Institute for R&D in Physics and Nuclear Engineering (IFIN-HH)

Copper-64 is a radioisotope of medical interest that could be used for positron emission tomography imaging and targeted radiotherapy of cancer. In this work,we investigated the possibility of producing the^(64)Cu isotope through a^(65)Cu(γ,n) reaction using high-intensity γ-beams produced at the extreme light infrastructurenuclear physics facility(ELI-NP). The specific activity for^(64)Cu was obtained as a function of target geometry, irradiation time, and electron beam energy, which translates into γ-beam energy. Optimized conditions for the generation of^(64)Cu isotopes at the ELI-NP were discussed. We estimated that an achievable saturation specific activity is of the order of 1–2 m Ci/g for thin targets(radius 1–2 mm,thickness 1 cm) and for a γ-beam flux of 10^(11) s ~1. Based on these results, the ELI-NP could provide great potential for the production of some innovative radioisotopes of medical interest in sufficient quantities suitable for nuclear medicine research.

关键词：放射性同位素设施生产中子反应射线束正电子发射断层成像医用靶向治疗基础设施

High-energy hybrid femtosecond laser system demonstrating 2 × 10 PW capability

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High Power Laser Science and Engineering 2020年第4期8卷 108-122页

作者： Fran?ois Lureau Guillaume Matras Olivier Chalus Christophe Derycke Thomas Morbieu Christophe Radier Olivier Casagrande Sébastien Laux Sandrine Ricaud Gilles Rey Alain Pellegrina Caroline Richard Laurent Boudjemaa Christophe Simon-Boisson Andrei Baleanu Romeo Banici Andrei Gradinariu Constantin Caldararu Bertrand De Boisdeffre Petru Ghenuche Andrei Naziru Georgios Kolliopoulos Liviu Neagu Razvan Dabu Ioan Dancus Daniel Ursescu Thales LAS France Thales Systems Romania extreme light infrastructure – nuclear physics ‘Horia Hulubei' National Institute for Physics and Nuclear Engineering University of Bucharest Faculty of Physics

We report on a two-arm hybrid high-power laser system(HPLS) able to deliver 2 × 10 PW femtosecond pulses,developed at the Bucharest-Magurele extreme light infrastructure nuclear physics(ELI-NP) Facility. A hybrid frontend(FE) based on a Ti:sapphire chirped pulse amplifier and a picosecond optical parametric chirped pulse amplifier based on beta barium borate(BBO) crystals, with a cross-polarized wave(XPW) filter in between, has been *** delivers 10 mJ laser pulses, at 10 Hz repetition rate, with more than 70 nm spectral bandwidth and high-intensity contrast, in the range of 1013:1. The high-energy Ti:sapphire amplifier stages of both arms were seeded from this common FE. The final high-energy amplifier, equipped with a 200 mm diameter Ti:sapphire crystal, has been pumped by six 100 J nanosecond frequency doubled Nd:glass lasers, at 1 pulse/min repetition rate. More than 300 J output pulse energy has been obtained by pumping with only 80% of the whole 600 J available pump energy. The compressor has a transmission efficiency of 74% and an output pulse duration of 22.7 fs was measured, thus demonstrating that the dual-arm HPLS has the capacity to generate 10 PW peak power femtosecond pulses. The reported results represent the cornerstone of the ELI-NP 2 × 10 PW femtosecond laser facility, devoted to fundamental and applied nuclear physics research.

关键词： lasers high-power laser pulses ultra-short laser pulses

A data-based photonuclear simulation algorithm for determining specific activity of medical radioisotopes

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nuclear Science and Techniques 2016年第5期27卷 160-167页

作者： Wen Luo Dimiter L.Balabanski Dan Filipescu School of nuclear Science and Technology University of South ChinaHengyang 421001China extreme light infrastructure-nuclear physics(ELI-NP)/"Horia Hulubei"National Institute for R&D in physics and nuclear Engineering(IFIN-HH) 30 Reactorului St.Bucharest-Magurelejud.IlfovP.O.B.MG-6077125 IasiRomania

For simulating more accurately neutron or proton production from photonuclear reactions,a data-based photonuclear reaction simulation algorithm has been *** photonuclear cross sections from evaluated or experimental database are chosen as input *** checking the validity of the use of the data-based photonuclear algorithm,benchmarking simulations are presented in *** calculate photonuclear cross sections or reaction yield for ~9Be,^(48)Ti,^(133)Cs,and ^(197)Au and compare them with experimental data in the region of incident photon energy below ~30 *** Geant4 can hardly reproduce photonuclear experimental data,results obtained from the data-based photonuclear algorithm are found in good agreement with experimental *** application in estimation of specific activity of radioisotopes is further *** conclude that the developed data-based photonuclear algorithm is suitable for an accurate prediction of photoninduced neutron or proton productions.

关键词：放射性同位素模拟算法医用光核反应实验数据 Geant4 光子能量输入数据

Fusion reactions around the barrier for Be+^(238)U

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Chinese physics C 2021年第5期45卷 100-104页

作者： Bo Mei Dimiter L.Balabanski Wei Hua Yu-Hu Zhang Xiao-Hong Zhou Cen-Xi Yuan Jun Su Sino-French Institute of nuclear Engineering and Technology Sun Y at-sen UniversityZhuhai 519082China Institute of Modern physics Chinese Academy of SciencesLanzhou 730000China extreme light infrastructure nuclear physics “Horia Hulubei”National R&D Institute for Physics and Nuclear EngineeringStrada Reactorului 30077125 Bucharest MagureleRomania

Fusion-evaporation cross sections of^(238)U(^(9)Be,5n)^(242)Cm are measured over a wide energy range around the Coulomb *** measured cross sections are compared with model calculations using two codes,namely HIVAP2 and KE ***2 calculations overestimate the measured fusion-evaporation cross sections by a factor of approximately *** KEWPIE2 calculations,two approaches,namely the Wentzel-Kramers-Brillouin(WKB)approximation and the empirical barrier-distribution(EBD)method,are used for the capture probability;both of them properly describe the measured cross ***,fusion cross sections of^(7.9)Be+^(238)Umeas-ured in two experiments are applied to constrain model calculations further through three codes,i.e,HIVAP2,KEWPIE2,and *** in these codes are also examined by comparison with measured fusion cross *** the comparisons indicate that the K EWPIE2 calculations using the WKB approximation agree well with the measured cross sections of both fusion reactions 7.9 Be+^(238)U and the fusion-evaporation reaction 238U(9 Be,5n)242 *** using the fusion code CCFULL are also in good agreement with the measured fusion cross sections of 7.9 Be+^(238)U.

关键词： fusion-evaporation reaction ^(238)U fusion cross sections near barrier energies

Electron Acceleration by a radially polarised cosh-Gaussian laser beam in vacuum

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Communications in Theoretical physics 2021年第9期73卷 124-128页

作者： Jitender Singh Jyoti Rajput Harjit Singh Ghotra Niti Kant Department of physics Lovely Professional UniversityG.T.RoadPhagwara(144411)PunjabIndia extreme light infrastructure-nuclear physics(ELI-NP) Horia Hulubei NIPNE30 Reactorului Street077125 MagureleJud.IifovRomania

In this paper,a radially polarised cosh-Gaussian laser beam(CGLB)is used to study the electron acceleration produced in vacuum.A highly energetic electron beam can be achieved by a CGLB,even with comparatively low-powered *** properties of a CGLB cause it to focus earlier,over a shorter duration than a Gaussian laser beam,which makes it suitable for obtaining high energies over small *** is found that the energy gained by the electrons strongly depends upon the decentering parameter of the laser *** is also observed that for a fixed value of energy gain,if the decentering parameter is increased,then the intensity of the laser field *** dependence of the energy gained by electrons on the laser intensity and the laserspot size is also studied.

关键词： cosh-Gaussian laser beam vacuum electron acceleration decentered parameter

Fabrication of micrometre-sized periodic gratings in free-standing metallic foils for laser-plasma experiments

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High Power Laser Science and Engineering 2022年第1期10卷 17-31页

作者： C.C.Gheorghiu M.Cerchez E.Aktan R.Prasad F.Yilmaz N.Yilmaz D.Popa O.Willi V.Leca extreme light infrastructure-nuclear physics Horia Hulubei National Institute for Physics and Nuclear Engineering077125 MagureleRomania Institut fur Laser-und Plasmaphysik Heinrich-Heine-Universitat40225 DiisseldorfGermany

Engineered targets are expected to play a key role in future high-power laser experiments calling for joined, extensive knowledge in materials properties, engineering techniques and plasma physics. In this work, we propose a novel patterning procedure of self-supported 10 μm thick Au and Cu foils for obtaining micrometre-sized periodic gratings as targets for high-power laser applications. Accessible techniques were considered, by using cold rolling, electronbeam lithography and the Ar-ion milling process. The developed patterning procedure allows efficient control of the grating and foil surface on large area. Targets consisting of patterned regions of 450 μm × 450 μm, with 2 μm periodic gratings, were prepared on 25 mm × 25 mm Au and Cu free-standing foils, and preliminary investigations of the microtargets interacting with an ultrashort, relativistic laser pulse were performed. These test experiments demonstrated that,in certain conditions, the micro-gratings show enhanced laser energy absorption and higher efficiency in accelerating charge particle beams compared with planar thin foils of similar thickness.

关键词： laser driven plasmas on structured targets metallic foils micro-grating patterned targets

Beam Line Design of Compact Laser Plasma Accelerator

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Chinese physics Letters 2017年第5期34卷 44-47页

作者：朱军高朱昆陶立耿易星林晨马文君卢海洋赵研英陆元荣陈佳洱颜学庆 State Key Laboratory of nuclear physics and Technology Peking University Collaborative Innovation Center of extreme Optics Shanxi University

A compact laser plasma accelerator that is a novel accelerator based on the interaction of ultra-intense laser and plasmas is being built now at Peking University. According to the results of experiments and numerical simulations, a beam line combining the advantages of quadrupole and analyzing magnets is designed to deliver proton beams with energy ranging from 1 to 44MeV, energy spread within ±5% and 10^6-8 protons per pulse. It turns out that the existence of space charge force of protons can be ignored for the increase of transverse and longitudinal envelopes even in the case of 10^9 protons in one pulse. To cope with the challenge to obtain a uniform distribution of protons at the final experiment target in laser acceleration, we manipulate the envelope beam waist in the Y direction to a proper position and obtain a relatively good distribution uniformity of protons with an energy spread of 0-±5%0.

关键词： Beam Line Design of Compact Laser Plasma Accelerator

High-energy hybrid femtosecond laser system demonstrating 2×10 PW capability

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High Power Laser Science and Engineering 2020年第4期8卷 104-118页

作者： François Lureau Guillaume Matras Olivier Chalus Christophe Derycke Thomas Morbieu Christophe Radier Olivier Casagrande Sébastien Laux Sandrine Ricaud Gilles Rey Alain Pellegrina Caroline Richard Laurent Boudjemaa Christophe Simon-Boisson Andrei Baleanu Romeo Banici Andrei Gradinariu Constantin Caldararu Bertrand De Boisdeffre Petru Ghenuche Andrei Naziru Georgios Kolliopoulos Liviu Neagu Razvan Dabu Ioan Dancus Daniel Ursescu Thales LAS France 78990 ElancourtFrance Thales Systems Romania 060071 BucurestiRomania extreme light infrastructure-nuclear physics ‘Horia Hulubei’National Institute for Physics and Nuclear Engineering077125 Bucharest MagureleRomania University of Bucharest Faculty of Physics077125 Bucharest MagureleRomania

We report on a two-arm hybrid high-power laser system(HPLS)able to deliver 2×10 PW femtosecond pulses,developed at the Bucharest-Magurele extreme light infrastructure nuclear physics(ELI-NP)Facility.A hybrid frontend(FE)based on a Ti:sapphire chirped pulse amplifier and a picosecond optical parametric chirped pulse amplifier based on beta barium borate(BBO)crystals,with a cross-polarized wave(XPW)filter in between,has been *** delivers 10 mJ laser pulses,at 10 Hz repetition rate,with more than 70 nm spectral bandwidth and high-intensity contrast,in the range of 1013:*** high-energy Ti:sapphire amplifier stages of both arms were seeded from this common *** final high-energy amplifier,equipped with a 200 mm diameter Ti:sapphire crystal,has been pumped by six 100 J nanosecond frequency doubled Nd:glass lasers,at 1 pulse/min repetition *** than 300 J output pulse energy has been obtained by pumping with only 80%of the whole 600 J available pump *** compressor has a transmission efficiency of 74%and an output pulse duration of 22.7 fs was measured,thus demonstrating that the dual-arm HPLS has the capacity to generate 10 PW peak power femtosecond *** reported results represent the cornerstone of the ELI-NP 2×10 PW femtosecond laser facility,devoted to fundamental and applied nuclear physics research.

关键词： lasers high-power laser pulses ultra-short laser pulses

ReLaX:the Helmholtz International Beamline for extreme Fields high-intensity short-pulse laser driver for relativistic laser-matter interaction and strong-field science using the high energy density instrument at the European X-ray free electron laser fac

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High Power Laser Science and Engineering 2021年第4期9卷 144-159页

作者： A.Laso Garcia H.Höppner A.Pelka C.Bähtz E.Brambrink S.Di Dio Cafiso J.Dreyer S.Göde M.Hassan T.Kluge J.Liu M.Makita D.Möller M.Nakatsutsumi T.R.Preston G.Priebe H.-P.Schlenvoigt J.-P.Schwinkendorf M.šmíd A.-M.Talposi M.Toncian U.Zastrau U.Schramm T.E.Cowan T.Toncian Helmholtz-Zentrum Dresden-Rossendorf 01328 DresdenGermany European XFEL 22869 SchenefeldGermany extreme light infrastructure-nuclear physics and Faculty of physics University of Bucharest077126 MagureleRomania Technische Universität Dresden 01062 DresdenGermany

High-energy and high-intensity lasers are essential for pushing the boundaries of *** development has allowed leaps forward in basic research areas,including laser±plasma interaction,high-energy density science,metrology,biology and medical *** Helmholtz International Beamline for extreme Fields user consortium contributes and operates two high-peak-power optical lasers using the high energy density instrument at the European X-ray free electron laser(EuXFEL)*** lasers will be used to generate transient extreme states of density and temperature to be probed by the X-ray *** paper introduces the ReLaX laser,a short-pulse high-intensity Ti:Sa laser system,and discusses its characteristics as available for user *** will also present the first experimental commissioning results validating its successful integration into the EuXFEL infrastructure and viability as a relativisticintensity laser driver.

关键词： X-ray free electron laser high-intensity laser relativistic intensity laser Ti:Sa laser