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Diophantine equations and Fermat's last theorem for multivariate(skew-)polynomials

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Applied Mathematics(A Journal of Chinese Universities) 2024年第1期39卷 159-173页

作者： PAN Jie JIA Yu-ming LI Fang School of Mathematical Sciences Zhejiang UniversityHangzhou 310058China Henan experimental High School Zhengzhou 450003China

Fermat’s Last Theorem is a famous theorem in number theory which is diﬃcult to ***,it is known that the version of polynomials with one variable of Fermat’s Last Theorem over C can be proved very *** aim of this paper is to study the similar problems about Fermat’s Last Theorem for multivariate(skew)-polynomials with any characteristic.

关键词： Fermat's last theorem polynomial ring skew polynomial ring

Two become one:combination of two risk factors in a new glaucoma animal model

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Neural Regeneration Research 2024年第5期19卷 982-983页

作者： Nils Kluge Sabrina Reinehr experimental Eye Research Institute University Eye HospitalRuhr-University BochumBochumGermany

Glaucoma is a group of eye diseases characterized by progressive loss of retinal ganglion cells(RGCs)and optic nerve *** this process,the visual field is reduced,and blindness may ultimately ***,glaucoma is the second leading cause of blindness,with about 80 million people *** is a multifactorial disease and due to its complexity,the exact pathomechanisms are not fully understood ***,different risk factors,such as elevated intraocular pressure(IOP),age,or myopia,have been identified to date(EGS,2021).

关键词： elevated exact glaucoma

Role of doxycycline in the treatment of dengue infection: An open-label, randomized, controlled, pilot trial

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Asian Pacific Journal of Tropical Medicine 2024年第4期17卷 160-165页

作者： Banothu Vinod Kumar Kajal Kamboj Ashok Kumar Pannu Ashok Kumar Yadav Mandip Bhatia Atul Saroch Department of Internal Medicine PGIMER ChandigarhIndia Department of experimental Medicine&Biotechnology PGIMER ChandigarhIndia

Objective:To measure the effect of doxycycline on inflammatory marker[IL-6,TNF-α,ferritin and C reactive protein(CRP)]levels in patients with dengue ***:A single-centre,open-label,parallel-group randomized controlled trial was done in PGIMER Chandigarh from June 2021 to October *** were randomized using a simple randomization process into two groups:the doxycycline treatment group(n=35)and the control group(n=34).Patients in the treatment group were given oral doxycycline 100 mg twice daily for five days along with standard treatment,whereas patients in the control group received only standard *** objective was to measure the effect of doxycycline on inflammatory markers in dengue ***:On comparative analysis at day 5,there was a statistically significant reduction in the median values of ferritin and CRP in cases compared to the control group(ferritin:P=0.006 and CRP:P=0.006).No significant reduction was noted in the levels of IL-6 and TNF-α.Conclusions:Doxycycline treatment led to a reduction of inflammatory markers in dengue infection.

关键词： Dengue Cytokine Doxycycline Serum ferritin C reactive protein

Investigation of surface textures deterioration on pavement skid-resistance using hysteresis friction models and numerical simulation method

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Friction 2024年第4期12卷 745-779页

作者： Haoyuan LUO Siyu CHEN Leyi ZHU Xiyin LIU Yangzezhi ZHENG Runming ZHAO Xiaoming HUANG School of Transportation Southeast UniversityNanjing 211189China National Demonstration Center for experimental Education of Road and Traffic Engineering Southeast UniversityNanjing 211189China

Many rubber friction theories or some method combined theories and field-experiments are employed to evaluate the pavement skid-resistance deterioration due to the evolution of surface ***,these methods are difficult to be implemented in the analysis of situations with multi-factor coupling and some extreme *** study developed a framework to evaluate the skid-resistance deterioration of asphalt *** this framework,the portable laser scanning was used to create the digital worn pavement model,and a hydroplaning finite element(FE)model for these digital worn pavements was constructed to evaluate coupling effects of the texture evolution and factors of slip ratio,slip angle,velocity and water film on braking-cornering characteristics of *** this study,the deterioration of skid-resistance of five typical asphalt pavements due the surface texture wear was systematically investigated by this *** with previous works,this study established the rubber friction models for each digital worn pavement considering the energy hysteresis of rubber and the power spectrum density of surface *** the rubber friction model was used to define the interaction behaviors between the tire and corresponding wore pavements in the FE hydroplaning model,rather than using an empirical friction model or a fixed friction coefficient.

关键词： worn pavement skid-resistance friction coefficient textures evolution water film computer numerical simulation

Coupling of reduced inorganic fertilizer with plant-based organic fertilizer as a promising fertilizer management strategy for colored rice in tropical regions

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Journal of Integrative Agriculture 2024年第1期23卷 93-107页

作者： Tingcheng Zhao Aibin He Mohammad Nauman Khan Qi Yin Shaokun Song Lixiao Nie Research Center for Physiology and ecology and Green Cultivation of Tropical Crops School of Breeding and Multiplication(Sanya Institute of Breeding and Multiplication)Hainan UniversitySanya 572000China

Colored rice is a type of high-quality,high-added-value rice that has attracted increasing attention in recent *** use of large amounts of inorganic nitrogen fertilizer in rice fields results in low fertilizer use efficiency and high environmental *** fertilizer is a promising way to improve soil quality and sustain high ***,most studies focus on the effect of animal-based organic *** effects of different ratios of plantbased organic fertilizer and inorganic fertilizer on the grain yield and quality of colored rice have rarely been ***,a two-year field experiment was conducted in 2020 and 2021 to study the effects of replacing inorganic N fertilizers with plant-based organic fertilizers on the yield,nitrogen use efficiency(NUE),and anthocyanin content of two colored rice varieties in a tropical region in *** experimental treatments included no nitrogen fertilization(T1),100% inorganic nitrogen fertilizer(T2),30%inorganic nitrogen fertilizer substitution with plant-based organic fertilizer(T3),60%inorganic nitrogen fertilizer substitution with plant-based organic fertilizer(T4),and 100% plantbased organic fertilizer(T5).The total nitrogen provided to all the treatments except T1 was the same at 120 kg *** results showed that the T3 treatment enhanced the grain yield and anthocyanin content of colored rice by increasing nitrogen use efficiency compared with *** average,grain yields were increased by 9 and 8%,while the anthocyanin content increased by 16 and 10% in the two colored rice varieties under T3 across the two years,respectively,as compared with *** study of the residual effect of partial substitution of inorganic fertilizers showed that the substitution of inorganic fertilizer with plant-based organic fertilizer improved the soil physiochemical properties,and thus increased the rice grain yield,in the subsequent *** highest grain yield of the subsequent rice crop was observe

关键词： colored rice organic fertilizer soil quality grain yield anthocyanin

Hole-Doped Nonvolatile and Electrically Controllable Magnetism in van der Waals Ferroelectric Heterostructures

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Chinese Physics Letters 2024年第5期41卷 107-119页

作者：姜新新王智宽李冲孙雪莲杨磊李冬梅崔彬刘德胜 School of Physics National Demonstration Center for Experimental Physics EducationShandong UniversityJinan 250100China School of Physics and Microelectronics Zhengzhou UniversityZhengzhou 450001China

Electrical control of magnetism in van der Waals semiconductors is a promising step towards development of two-dimensional spintronic devices with ultralow power consumption for processing and storing ***, we propose a design for two-dimensional van der Waals heterostructures(vdWHs) that can host ferroelectricity and ferromagnetism simultaneously under hole doping. By contacting an In Se monolayer and forming an InSe/In_(2)Se_(3) vd WH, the switchable built-in electric field from the reversible out-of-plane polarization enables robust control of the band alignment. Furthermore, switching between the two ferroelectric states(P_↑ and P_↓)of hole-doped In_(2)Se_(3) with an external electric field can interchange the ON and OFF states of the nonvolatile magnetism. More interestingly, doping concentration and strain can effectively tune the magnetic moment and polarization energy. Therefore, this provides a platform for realizing multiferroics in ferroelectric heterostructures,showing great potential for use in nonvolatile memories and ferroelectric field-effect transistors.

关键词： polarization ferroelectric doping

A Transcriptome Analysis of Neural Tissue of Litopenaeus vannamei After Acute Exposure to Alexandrium pacificum

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Journal of Ocean University of China 2024年第2期23卷 529-538页

作者： YANG Huijie HUANG Xianghu MA Yukun HU Zhangxi ZHANG Ning LI Changling ZHANG Yulei Department of Aquaculture College of FisheriesGuangdong Ocean UniversityZhanjiang 524088China Guangdong Laboratory of Marine ecology Environment Monitoring and Warning Zhanjiang 524088China

Alexandrium pacificum(***)is a typical paralytic shellfish poisonous *** algal blooms(HABs)caused by this species can bring serious environmental problems and economic losses to the aquaculture *** this study,transcriptome sequencing and analyses were performed on the neural tissue of Litopenaeus vannamei(***)after acute exposure to *** disrupted solution for 72 h,and differentially expressed genes(DEGs)were *** results showed that,compared with the control samples,300 DEGs were identified in the experimental group,of which 194 were up-regulated,and 106 *** gene ontology(GO)functional enrichment analysis showed that DEGs were significantly enriched in the cortical cytoskeleton organization,troponin complex,amylo-alpha-1,6-glucosidase and thymidine *** encyclopedia of genes and genomes(KEGG)enrichment analysis found that DEGs were mainly enriched in the oxidative phosphorylation process,intercellular tight junctions and *** results showed that the proteoglycans,signaling pathways,and various metabolic processes that regulate cell proliferation,differentiation,and apoptosis all played an essential role in the response of *** to *** toxins.

关键词： Litopenaeus vannamei Alexandrium pacificum paralytic shellfish poisoning transcriptome nerve

Current and future trends in whole genome sequencing in cancer

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Cancer Biology & Medicine 2024年第1期21卷 16-20页

作者： Yuki Katsuya Department of experimental Therapeutics National Cancer Center Hospital5-1-1 TsukijiChuo-kuTokyo 104-0045Japan

Cancer remains a formidable global health challenge affecting millions of lives *** decades,conventional cancer treatments used a one-size-fits-all approach,overlooking the intricate genetic variations that drive *** emergence of cancer genomics has ushered in a new era of personalized and targeted cancer *** Human Genome Project,which was launched in 1990 and completed in 2003。

关键词： cancer Cancer annually

Effectively modulating spatial vortex four-wave mixing in a diamond atomic system

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Chinese Physics B 2024年第4期33卷 473-478页

作者：巴诺姜明奇费金友王丹蒋海林王磊王海华 National Demonstration Center for experimental Physics Education College of PhysicsJilin Normal UniversitySiping 136000China College of Physics Jilin UniversityChangchun 130012China

Due to the spatial characteristics of orbital angular momentum,vortex fields can be applied in the fields of quantum storage and quantum *** study the realization of spatially modulated vortex fields based on four-wave mixing in a four-level atomic system with a diamond *** intensity and spiral phase of the vortex field are effectively transferred to the generated four-wave mixing *** changing the detuning of the probe field,the phase and intensity of the generated vertex four-wave mixing field can be *** the probe field takes a large detuning value,the spatial distribution of the intensity and phase of the vertex four-wave mixing field can be effectively tuned by adjusting the Rabi frequency or detuning value of the coupled *** the same time,we also provide a detailed explanation based on the dispersion relationship,and the results agree well with our simulation results.

关键词： coherent optical effects four-wave mixing orbital angular momentum