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Field survey and analysis on near-fault severely damaged high-speed railway bridge in 2022 M6.9 Menyuan earthquake

earthquake Engineering and Engineering Vibration 2024年第4期23卷 1043-1055页

作者： Lin Xuchuan Liu Fuxiang Shan Wenchen Key laboratory of earthquake Engineering and Engineering Vibration Institute of Engineering MechanicsChina Earthquake AdministrationHarbin 150080China Key laboratory of earthquake Disaster Mitigation Ministry of Emergency ManagementHarbin 150080China Institute of Smart City and Intelligent Transportation Southwest Jiaotong UniversityChengdu610000China

The 2022 M6.9 Menyuan earthquake caused severe damage to a high-speed railway bridge,which was designed for high-speed trains running at speeds of above 250 km/h and is located right next to the *** of this type have been widely used for rapidly constructing the high-speed railway network,but few bridges have been tested by near-fault devastating *** potential severe impact of the earthquake on the high-speed railway is not only the safety of the infrastructure,trains and passengers,but also economic loss due to interrupted railway ***,a field survey was carried out immediately after the earthquake to collect time-sensitive *** damage to the bridge was carefully investigated,and quantitative analyses were conducted to better understand the mechanism of the bridge *** was found that seismic action perpendicular to the bridge’s longitudinal direction caused severe damage to the girders and rails,while none of the piers showed obvious deformation or *** maximum values of transverse displacement,out-of-plane rotation and twisting angle of girders reached 212.6 cm,3.1 degrees and 19.9 degrees,respectively,causing severe damage to the bearing supports and anti-seismic retaining *** observations provide a basis for improving the seismic design of high-speed railway bridges located in near-fault areas.

关键词： Menyuan earthquake field survey high-speed railway bridge near fault seismic damage

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Seismic fragility analysis of three-tower cable-stayed bridges with different connection configurations

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earthquake Engineering and Engineering Vibration 2024年第4期23卷 1009-1027页

作者： Chen Chen Liu Jinlong Lin Junqi Li Suchao Key laboratory of earthquake Engineering and Engineering Vibration Institute of Engineering MechanicsChina Earthquake AdministrationHarbin 150080China Key laboratory of earthquake Disaster Mitigation Ministry of Emergency ManagementHarbin 150080China Key laboratory of Structural Dynamic Behavior and Control Ministry of EducationHarbin Institute of TechnologyHarbin 150090China

Seismic fragility analysis of three-tower cable-stayed bridges with three different structural systems,including rigid system(RS),floating system(FS),and passive energy dissipation system(PEDS),is conducted to study the effects of connection configurations on seismic responses and *** element models of bridges are established using OpenSees.A new ground motion screening method based on the statistical characteristic of the predominant period is proposed to avoid irregular behavior in the selection process of ground motions,and incremental dynamic analysis(IDA)is performed to develop components and systems fragility *** effects of damper failure on calculated results for PEDS are examined in terms of seismic response and fragility *** results show that the bridge tower is the most affected component by different structural *** RS,the fragility of the middle tower is significantly higher than other components,and the bridge failure starts from the middle tower,exhibiting a characteristic of local *** FS and PEDS,the fragility of the edge tower is higher than the middle *** system fragility of RS is higher than FS and *** the failure of dampers into account is necessary to obtain reliable seismic capacity of cable-stayed bridges.

关键词： seismic fragility cable-stayed bridge connection configuration viscous damper comparison analysis

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Proper interpretation of sectional analysis results

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earthquake Research Advances 2024年第2期4卷 65-71页

作者： Juyuan Zheng Yuli Huang Zhe Qu Key laboratory of earthquake Engineering and Engineering Vibration Institute of Engineering MechanicsChina Earthquake AdministrationHarbin150080China Key laboratory of earthquake Disaster Mitigation Ministry of Emergency ManagementHarbin150080China Arup 560 Mission StreetSuite 700San FranciscoCA94105United States

Displacement control algorithms commonly used to evaluate axial force-bending moment(PM)diagrams may lead to incorrect interpretations of the strength envelopes for asymmetric *** paper aims to offer valuable insights by comparing existing displacement control algorithms with a newly proposed force control *** main focus is on the PM diagrams of three example sections that exhibit varying degrees of *** comparative study indicates that conventional displacement control algorithms inevitably introduce non-zero out-of-plane bending *** reported PM diagram in such cases erroneously neglects the out-of-plane moment and fails to represent the strength envelope *** oversight results in significant and unconservative errors when verifying the strength of asymmetric sections.

关键词： Fiber section model Axial force-moment interaction diagram Limit state Failure surface

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Deep electrical structures of Qinzhou-Fangcheng Junction Zone in Guangxi and seismogenic environment of the 1936 Lingshan M6^(3/4)earthquake

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Science China Earth Sciences 2024年第2期67卷 584-603页

作者： Bin ZHOU Chunheng YAN Yan ZHAN Xiangyu SUN Sha LI Xiang WEN Yajun MO Yongdong YUAN Yuan YUAN Meili HUANG earthquake Agency of Guangxi Zhuang Autonomous Region Nanning530022China State Key laboratory of earthquake Dynamics Institute of GeologyChina Earthquake AdministrationBeijing100029China Guangxi Geophysical Survey Institute Liuzhou545005China

The tectonic position of the southwest section of the Qinzhou Bay-Hangzhou Bay Tectonic Junction Zone(QHTJZ)can be determined by examining the Qinzhou-Fangcheng Junction Zone(QFJZ)in *** zone is significant because it was the location of the largest earthquake ever recorded in the inland region of South China,specifically the 1936 Lingshan M6^(3/4)earthquake in ***,this region serves as an optimal location for researching the origins of intraplate earthquakes in South *** study presents a display of a broadband magnetotelluric(MT)prospecting profile that traverses the Guangxi QFJZ and the Lingshan earthquake zone,extending from the northwest(NW)to the southeast(SE).A resistivity structure model was generated using three-dimensional(3D)inversion technology along the *** main faults in QFJZ were analyzed in terms of their deep extension forms and tectonic *** analysis was performed by integrating the results obtained from geology,gravity,wave velocity ratio,Global Position System(GPS),and geothermal *** results showed that(1)the Dongzhong-Xiaodong fault(DXf),the eastern Fangcheng-Lingshan fault(FLf2),and the eastern Hepu-Beiliu fault(HBf2)were all trans-crustal deep faults,and crust-mantle ductile shear zones developed in the deep *** electrical boundary zones,DXf and HBf2,were *** inclined towards the northwest,while HBf2 inclined towards the *** FangchengLingshan fault(FLf)exhibits a tectonic style resembling a“flower”shape in the upper *** the deeper section,it is characterized by an electrical boundary zone that gradually slopes towards the southeast direction.(2)The Hunan-Guangxi Passive Continental Margin(HGPCM)on the NW side of DXf had a stratified resistivity structure and relatively stable Bouguer gravity anomalies,which conformed to the quasi-craton tectonic attribute of the local failure at the southeastern margin of the Yangtze Block(YB).The southeastern side of this bloc

关键词： South China Block Qinzhou-Fangcheng Junction Zone Magnetotelluric 1936 Lingshan M6^(3/4)earthquake Deep seismogenic environment

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Mimotope peptide modified pompon mum-like magnetic microparticles for precise recognition,capture and biotransformation analysis of rituximab in biological fluids

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Acta Pharmaceutica Sinica B 2024年第3期14卷 1317-1328页

作者： Jiawen Yang Aixuan Zhou Minyi Li Qiaoxian He Jingwei Zhou Jacques Crommen Wentao Wang Zhengjin Jiang Qiqin Wang Institute of Pharmaceutical analysis College of Pharmacy/State Key Laboratory of Bioactive Molecules and Druggability Assessment/International Cooperative Laboratory of Traditional Chinese Medicine Modernization and Innovative Drug Development of Ministry of Education(MOE)of ChinaJinan UniversityGuangzhou 510632China laboratory for the analysis of Medicines Department of Pharmaceutical SciencesCIRMUniversity of LiegeLiege B-4000Belgium SCIEX Shanghai 200050China

Due to low immobilized ligand density,limited binding capacity,and severe interference from serum proteins,developing ideal peptide-based biomaterials for precise recognition and in vivo analysis of biopharmaceuticals remains a huge *** this study,mimotope peptide modified pompon mum-like biomimetic magnetic microparticles(MMPs,3.8μm)that mimic the specific functionalities of CD20 on malignant B cells were developed for the first *** from the numerous ligand binding sites(Ni^(2+))on the pompon mum-like MMPs,these novel materials achieved≥10 times higher peptide ligand densities(>2300 mg/g)and antibody binding capacities(1380 mg/g)compared to previous reported *** the high specificity of the mimotope peptide,rituximab can be precisely recognized and enriched from cell culture media or serum *** also established an LC-MS/MS method using the MMPs for tracking rituximab biotransformation in patient ***,deamidation of Asn55 and Asn33,as well as oxidation of Met81 and Met34 were observed at the key complementarity determining regions of rituximab,which could potentially influence antibody function and require careful ***,these versatile biomimetic MMPs demonstrate superior recognition and enrichment capabilities for target antibodies,offering interesting possibilities for biotransformation analysis of biopharmaceuticals in patient serum.

关键词： Therapeutic monoclonal antibody Mimotope peptide Precise recognition Peptide-based biomaterials Biotransformation Patient serum

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Tectonic geomorphology of Türkiye and its insights into the neotectonic deformation of the Anatolian Plate

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earthquake Research Advances 2024年第1期4卷 23-35页

作者： Yuqiao Chang Yihui Zhang Huiping Zhang Yunnan earthquake Agency Kunming650216China State Key laboratory of earthquake Dynamics Institute of GeologyChina Earthquake AdministrationBeijing100029China

Quantitative geomorphic analyses are usually powerful in identifying active tectonics across global orogenic *** present study will focus on the Anatolian Plate which hosts a lot of recent catastrophic earthquakes in Tü*** geomorphic indices for 100 sub-basins around Türkiye have been computed including local relief,slope,normalized steepness index(k_(Sn)),hypsometric curve and integral(HI),transverse topographic symmetry factor(Tf),and the basin asymmetry factor(Af).The averaged kSnand Af values have shown four high-value anomalous zones,suggesting relatively high uplift rates featured by high river incision and regional *** values of 0.35≤HIanalysis suggest a relatively high degree of tectonic activity in the following four areas,the Isparta Angle,the Eastern Black Sea Mountains,the South-eastern Anatolia Region,and the Central Anatolian fault *** further suggest that the eastern part of the NAFZ,NEAFZ,EAFZ,and CAFZ will be more active in tectonic activities,with a greater potential for strong earthquake occurrence.

关键词： Geomorphic indices Quantitative Türkiye Tectonic activity

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Spatial correlations in ground motion intensity measuring from the 2023 Türkiye earthquake

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earthquake Research Advances 2024年第1期4卷 14-22页

作者： Guoliang Shao Ruizhi Wen Hongwei Wang Yeifei Ren Baofeng Zhou Key laboratory of earthquake Engineering and Engineering Vibration Institute of Engineering MechanicsChina Earthquake AdministrationHarbin150080 China Key laboratory of earthquake Disaster Mitigation Ministry of Emergency ManagementHarbin150080 China

When evaluating an area's seismic risk or resilience,it is necessary to use the spatial correlation to analyze the ground motion parameters of multiple sites together in an *** two large earthquakes in Türkiye provided the possibility for spatial correlation analysis of ground motion intensity measurements in this *** on the strong motion records provided by The Disaster and Emergency Management Authority of Türkiye(AFAD),this study uses the local ground motion prediction equation in Türkiye to give spatial correlation analysis of Intensity *** study gives an exponential model based on a semivariogram and compares it with the correlation model obtained from previous studies.

关键词： Spatial correlation Semi-variance Türkiye GMPE

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Rationally designed synthetic peptide as versatile calibrant to improve the accuracy of protein sequence analysis using MALDI mass spectrometry

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Chinese Chemical Letters 2024年第3期35卷 214-220页

作者： Lingpeng Zhan Yanyi Huang Guanbo Wang Institute for Cell analysis Shenzhen Bay LaboratoryShenzhen 518132China Biomedical Pioneering Innovation Center Peking UniversityBeijing 100871China

Matrix-assisted laser desorption/ionization(MALDI)mass spectrometry(MS)plays an indispensable role in analyzing protein covalent *** reliable identification of amino acid residues and modifications relies on the mass accuracy,which is highly dependent on ***,the accuracy provided by the currently available calibrants still needs further improvement in terms of compatibility with multiple tandem MS modes or ion polarity modes,calibratable range,and minimizing suppression of and interference with analyte *** aiming at developing a versatile calibrant to solve these problem,we designed a synthetic peptide format of calibrant R_x(GDP_n)_m(referred to as“Gly-Asp-Pro,GDP”)according to the chemical natures of amino acids and polypeptide fragmentation rules in tandem *** four types of amino acid residues selected and arranged through rational designs,a GDP peptide produces highly regulated fragments that give rise to evenly spaced signals in each tandem MS mode and is compatible with both positive and negative ion *** internal calibration,its regulated fragmentation pattern minimizes interference with analyte signals,and using a single peptide as the input minimizes suppression of the analyte *** demonstrated by analyses of proteins including monoclonal antibody and Aβ-42,these features allowed significant increase of the mass accuracy and precision,which improved sequence coverage and sequence resolution in sequence analyses(including de novo sequencing).This rational design strategy may also inspire further development of synthetic calibrants that benefit structural analysis of biomolecules.

关键词： Biomolecule design Synthetic peptide Protein sequencing Covalent structure De novo sequencing Mass spectrometry Gas-phase fragmentation

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analysis of faulting destruction and water supply pipeline damage from the first mainshock of the February 6,2023 Türkiye earthquake doublet

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earthquake Science 2024年第1期37卷 78-90页

作者： Xiaoqing Fan Libao Zhang Juke Wang Yefei Ren Aiwen Liu Institute of Geophysics China Earthquake AdministrationBeijing 100081China Institute of Engineering Mechanics China Earthquake AdministrationHarbin 150080China

In 2023,two consecutive earthquakes exceeding a magnitude of 7 occurred in Türkiye,causing severe casualties and economic *** damage to critical urban infrastructure and building structures,including highways,railroads,and water supply pipelines,was particularly severe in areas where these structures intersected the seismogenic *** infrastructure projects that traverse active faults are susceptible to the influence of fault movement,pulse velocity,and ground *** this study,we used a unique approach to analyze the acceleration records obtained from the seismic station array(9 strong ground motion stations)located along the East Anatolian Fault(the seismogenic fault of the MW7.8 mainshock of the 2023 Türkiye earthquake doublet).The acceleration records were filtered and integrated to obtain the velocity and displacement time *** used the results of an on-site investigation,jointly conducted by China earthquake Administration and Türkiye’s AFAD,to analyze the distribution of PGA,PGV,and PGD recorded by the strong motion array of the East Anatolian *** found that the maximum horizontal PGA in this earthquake was 3.0 g,and the maximum co-seismic surface displacement caused by the East Anatolian Fault rupture was 6.50 *** the fault rupture propagated southwest,the velocity pulse caused by the directional effect of the rupture increased gradually,with the maximum PGA reaching 162.3 cm/*** also discussed the seismic safety of critical infrastructure projects traversing active faults,using two case studies of water supply pipelines in Türkiye that were damaged by *** used a three-dimensional finite element model of the PE(polyethylene)water pipeline at the Islahiye State Hospital and fault displacement observations obtained through on-site investigation to analyze pipeline failure *** further investigated the effect of the fault-crossing angle on seismic safety of a pipeline,based on our analysis and the failure p

关键词： Türkiye earthquake fault displacement near-fault ground motion velocity pulse water supply pipeline

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Effect of boundary conditions on shakedown analysis of heterogeneous materials

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Applied Mathematics and Mechanics(English Edition) 2024年第1期45卷 39-68页

作者： Xiuchen GONG Yinghao NIE Gengdong CHENG Kai LI State Key laboratory of Structural analysis Optimization and CAE Software for Industrial EquipmentInternational Research Center for Computational MechanicsDepartment of Engineering MechanicsDalian University of TechnologyDalian 116023Liaoning ProvinceChina

The determination of the ultimate load-bearing capacity of structures made of elastoplastic heterogeneous materials under varying loads is of great importance for engineering analysis and design. Therefore, it is necessary to accurately predict the shakedown domains of these materials. The static shakedown theorem, also known as Melan's theorem, is a fundamental method used to predict the shakedown domains of structures and materials. Within this method, a key aspect lies in the construction and application of an appropriate self-equilibrium stress field(SSF). In the structural shakedown analysis, the SSF is typically constructed by governing equations that satisfy no external force(NEF) boundary conditions. However, we discover that directly applying these governing equations is not suitable for the shakedown analysis of heterogeneous materials. Researchers must consider the requirements imposed by the Hill-Mandel condition for boundary conditions and the physical significance of representative volume elements(RVEs). This paper addresses this issue and demonstrates that the sizes of SSFs vary under different boundary conditions, such as uniform displacement boundary conditions(DBCs), uniform traction boundary conditions(TBCs), and periodic boundary conditions(PBCs). As a result, significant discrepancies arise in the predicted shakedown domain sizes of heterogeneous materials. Built on the demonstrated relationship between SSFs under different boundary conditions, this study explores the conservative relationships among different shakedown domains, and provides proof of the relationship between the elastic limit(EL) factors and the shakedown loading factors under the loading domain of two load vertices. By utilizing numerical examples, we highlight the conservatism present in certain results reported in the existing literature. Among the investigated boundary conditions, the obtained shakedown domain is the most conservative under ***, utilizing PBCs to

关键词： heterogeneous material self-equilibrium stress field(SSF) shakedown analysis effect of boundary conditions

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