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Evolving paradigms for natural-product drug discovery

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National Science Review 2022年第11期9卷 10-11页

作者： Geoffrey A.Cordell College of Pharmacy University of Florida Natural products inc.

Natural products are an essential aspect of global human health. Integration of contemporary technologies based on the Fourth Industrial Revolution (4IR) and the Quintuple Helix is needed to discover additional metabo...

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Quantification of ventilation enhancement using the Eye CAN roof support

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International Journal of Mining Science and Technology 2017年第1期27卷 153-158页

作者： Shook Michael T Sindelar Mark F, Jiang Hua Luo Yi Burrell Mining products Inc.New KensingtonPA 15068USA Department of Mining Engineering West Virginia UniversityMorgantownWV 26506USA

Convergence of roof and floor in underground mine openings is a common occurrence. This convergence not only adversely affects the ability of workers, equipment and supplies to travel through the mine, it also reduces the effectiveness of the mine ventilation system, which is essential for the dilution of methane gas and airborne respirable dust. While installing secondary standing supports to control floor and roof convergence, such supports, by nature, partially obstruct a portion of the airway. These added obstructions inhibit the ability of the ventilation system to operate as efficiently as it could by increasing the resistance in and reducing the cross-sectional area of the airway. This study introduces and demonstrates the benefits of The Eye CAN^(TM) standing roof support, which controls floor and roof convergence and is less obstructive to air flow than conventional wooden cribs. Laboratory findings show that the normal resistance of a supported lined airway is reduced by using this new product from Burrell Mining products, inc., while providing the same roof support characteristics of an established product—The CANò. Load vs. displacement curves generated from laboratory tests demonstrated that this new product behaves with the same roof support characteristics as others in The CAN product family. Ventilation data gathered from a simulated mine entry was then used for computational fluid dynamics(CFD) *** CFD analysis showed an improvement with The Eye CAN vs. other accepted forms of standing roof support. This proof-of-concept study suggests that, when using this new product made by Burrell Mining products, inc., not only will the convergence from the roof and floor be controlled, but airway resistance will also be reduced.

关键词： Standing roof support CAN Ventilation Load-displacement Eye CAN

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用工业煤气生产钢铁的环境改善和价格作用

钢铁 2003年第Z1期38卷 158-161页

作者： David L. Runner Michael D. Lanyi Debabrata Saha Charles Chun Ru Zhao Air products and Chemicals Inc. USA Air Products and Chemicals Inc. USA Air Products and Chemicals Inc. USA Air Products China Inc.

历史上钢铁工业就是一个高能耗和影响环境的部门.在这个工业部门目前的工艺在不断提高,而且还会有较大改进.许多已实现的和待采用的革新仍受到制约,采用工业气体的技术也受到制约.工业气体对减少能量需求,减弱对环境的影响和改善整个钢... 详细信息

历史上钢铁工业就是一个高能耗和影响环境的部门.在这个工业部门目前的工艺在不断提高,而且还会有较大改进.许多已实现的和待采用的革新仍受到制约,采用工业气体的技术也受到制约.工业气体对减少能量需求,减弱对环境的影响和改善整个钢铁生产的成本等方面都起到重要作用.从一个工业气体供应商的观点概述了这一可能性,特别强调采用工业气体的技术可以克服环境问题.

关键词：工业煤气钢铁环境价格

Study on Synergy Effect in Dimethyl Ether Synthesis from Syngas

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Chinese Journal of Chemical Engineering 2001年第4期9卷 412-416页

作者：王志良刁杰王金福金涌 X.D.PENG 清华大学北京 100084 Air products & Chemicals inc 美国

Influence of reaction temperature, pressure and space velocity on the direct synthesis of dimethyl ether (DME) from syngas is studied in an isothermal fixed-bed reactor. The catalyst is a physical mixture of C301 copper-based methanol (MeOH) synthesis catalyst and ZSM-5 dehydration catalyst. The experimental results show that the chemical synergy between methanol synthesis reaction and methanol dehydration reaction is evident. The conversion of carbon monoxide is over 90%.

关键词： dimethyl ether chemical synergy methanol dehydration syngas

Advances in Liquid Phase Methanol (LPMEOHTM )and Dimethyl Ether (LPDMETM ) Technology

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Advances in Liquid Phase Methanol (LPMEOHTM )and Dimethyl Et...

Third Joint China/USA Chemical Engineering Conference

作者： X. D. Peng Peter J. A. Tijm B. A. Toseland Air products ＆ Chemicals inc. USA Air products ＆ Chemicals inc. USA Air products ＆ Chemicals inc. USA

＜正＞INTRODUCTION Driven by energy needs, environmental concerns and business requirements, there has been an increasing demand on utilising remote natural gas and developing clean coal technology. This has led to the development of a number of syngas （primarily a mixture of CO and H2 derived from coal or natural gas） conversion technologies around the world, among which is our Liquid Phase?（LP） technology. Since later 1980s, under the Clean Coal and Alternative Fuels Contracts from the US Department of Energy （DOE）, Air products ＆ Chemicals, inc. （APCI） has been developing liquid phase syngas conversion technologies. R＆D work have been conducted in our labs featuring 5 autoclave slurry phase reactors. A number of liquid phase processes, including syngas-to-methanol (LPMEOH?, syngas-to-DiMethyl Ether (LPDME?, Fischer-Tropsch, water gas shift and iso-butanol dehydration, have been demonstrated at the DOE owned, APCI-operated LaPorte Alternative Fuels Demonstration plant. The efforts have led to the present demonstration of LPMEOH?on commercial scale and a recent 10-tons-per-day （TPD） LPDME?demonstration at the LaPorte plant. This paper will describe the features, advantages and applications of the LP technology and the status of our LPMEOH?and LPDME?technology.

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制造烧结金属含油轴承的高性能青铜粉

粉末冶金技术 2007年第5期25卷 387-392页

作者： Nic Veloff Anil Nadkarni Thomas Murphy 韩凤麟（译） SCM Metal products Inc. 2601 week Dr. Research Triangle Park NC 27709 不详

自润滑青铜轴承的性能决定于许多因素的综合作用,诸如精整后的密度、径向压溃强度(RCS)、含油量、表面粗糙度、施加的载荷、轴的速度及孔隙结构。压坯与烧结体的密度以及烧结时的尺寸变化(DC),在轴承制造中都很重要。这篇文章阐述了生... 详细信息

自润滑青铜轴承的性能决定于许多因素的综合作用,诸如精整后的密度、径向压溃强度(RCS)、含油量、表面粗糙度、施加的载荷、轴的速度及孔隙结构。压坯与烧结体的密度以及烧结时的尺寸变化(DC),在轴承制造中都很重要。这篇文章阐述了生产高使用性能烧结轴承用的一系列新的青铜粉末。对使用性能的测定表明,与用标准的预混合青铜粉末制造的轴承相比,这些轴承摩擦系数较小,温升较低且稳定,而且径向压溃强度较高。性能优异是因为连通孔隙结构较细小,从而通过极好的毛细作用可吸入大量油。在理论上,较高的RCS可使轴承具有较高的承受载荷的能力。

关键词：粉末冶金自润滑轴承含油轴承青铜粉 S2G青铜粉

Listwise approaches based on feature ranking discovery

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Frontiers of Computer Science 2012年第6期6卷 647-659页

作者： Yongqing WANG Wenji MAO Daniel ZENG Fen XIA Commercial products Development Department Alibaba Inc.Hangzhou 310052China State Key Laboratory of Management and Control for Complex Systems Institute of AutomationChinese Academy of SciencesBeijing 100190China Department of Management Information Systems University of ArizonaTucsonAZ 85721USA Union Research and Development Department Baidu Inc.Beijing 100085China

Listwise approaches are an important class of learning to rank, which utilizes automatic learning techniques to discover useful information. Most previous research on listwise approaches has focused on optimizing ranking models using weights and has used imprecisely labeled training data; optimizing ranking models using features was largely ignored thus the continuous performance improvement of these approaches was hindered. To address the limitations of previous listwise work, we propose a quasi-KNN model to discover the ranking of features and employ rank addition rule to calculate the weight of combination. On the basis of this, we propose three listwise algorithms, FeatureRank, BL-FeatureRank, and DiffRank. The experimental results show that our proposed algorithms can be applied to a strict ordered ranking training set and gain better performance than state-of-the-art listwise algorithms.

关键词： learning to rank listwise approach feature's ranking discovery

Simultaneous rapid molecular differential diagnosis of respiratory pathogens,including Avian Flu virus

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Simultaneous rapid molecular differential diagnosis of respi...

Formic acid fractionation towards highly efficient cellulose-derived PdAg bimetallic catalyst for H_(2) evolution

2006年第二届新生病毒性疾病控制学术研讨会

作者：韩健 CSO Genaco Biomedical ProductsInc.

The clinical presentations for most infectious agents are often not specific enough to allow for a defirutive diagnosis. Coughing and fever, for example, are symptoms that may be caused by many different bacterial or viral infections. Thus, for better treatment and disease control, a molecular differential diagnostic (MDD) assay that can identify, differentiate, and pinpoint the offending pathogen associated with a clinical syndrome is needed. MDDs are essential tools for effective infectious disease surveillance, biodefense, and personalized medicine.

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Green Energy & Environment 2022年第1期7卷 172-183页

作者： Yanyan Yu Huanghui Xu Hongfei Yu Lihong Hu Yun Liu Beijing Key Laboratory of Bioprocess College of Life Science and TechnologyBeijing University of Chemical TechnologyBeijing100029China Beijing Zest Bridge Media Technology inc. Beijing100176China Institute of Chemical Industry of Forest products Chinese Academy of ForestryNanjing210042China

The present work,in which cellulose isolated from formic acid fractionation(FAC)is decorated with polyetherimide(PEI)to attain highly efficient cellulose-derived PdAgbimetallic catalyst(PdAg-PEI-FAC),has been investigated,and the catalyst properties are characterized by XRD,XPS,BET,ICP-AES and *** as-obtained Pd_(3.75)Ag_(3.75)-PEI-FAC exhibits excellent catalytic performance for H_(2)evolution from a sodium formate-free formic acid(FA)aqueous medium at ambient temperature and the turnover frequency(TOF)reaches a high value of 2875 h^(-1)which is superior to most of the previously reported Pd-based heterogeneous catalysts supported on a carbon matrix in the *** remarkable catalytic activities of PdAg-PEI-FAC result from high dispersion Pd and synergistic effects between the PdAg bimetallic ***,the amide(-NH)group in PEI coated on cellulose acting as a proton scavenger efficiently improves the catalytic property of *** addition,the critical factors affecting H;release,such as FA concentration,reaction temperature,PdAg compositions and support matrix type,are also *** on the experimental results,the probable three-step mechanism of H_(2)evolution from FA over Pd_(3.75)Ag_(3.75)-PEI-FAC is *** the end,the activation energy(Ea)of Pd_(3.75)Ag_(3.75)-PEI-FAC catalyst is calculated to 53.97 kJ mol^(-1),and this catalyst shows unique robustness and satisfactory re-usability with no loss of catalytic activity after five *** findings in this work provide a novel routine from lignocellulose fractionation towards cellulose-derived catalyst for H_(2)evolution.

关键词： Formic acid fractionation Cellulose modification Cellulose-derived PdAg bimetallic catalyst Hydrogen generation Mechanism