检索结果-南通市图书馆

History & Philosophy of Medicine 2020年第4期2卷 119-128页

作者： Wen-Jun Wang Shao-Jie Huang Juan-Li Zhang Yang Ma Fei Mu Yu-Cheng Liao Jing-Wen Wang Ai-Dong Wen Yi Ding Department of Pharmacy Xijing HospitalFourth Military Medical UniversityXi’an 710032China Department of Pharmacy Shaanxi University of Chinese MedicineXi’an 712046China

Taking the Qi and Yin deficiency syndrome as an example,the research method of pharmacology of syndrome management system was *** means of text mining,systematic pharmacology and target analysis,to attempt to reveal the essence of the corresponding syndrome by studying the drugs and targets of Qi and Yin *** Chinese herbs treating Qi and Yin deficiency were retrieved and used more than 30 times,and 9,317 related targets were *** common targets of action were *** analysis was carried out by using degree centrality,closeness centrality and betweenness centrality to confirm that estrogen receptor(ESR1),tumor necrosis factor(TNF),D(2)dopamine receptor(DRD2),vitamin D3 receptor(VDR),glucocorticoid receptor(NR3C1),acetylcholinesterase(ACHE)and endothelin-1(edn1)were highly correlated with Qi and Yin deficiency *** the target to find Qi and Yin deficiency syndrome corresponding to 17 categories of diseases.A new idea was provided for studying the biological essence of TCM clinical syndrome differentiation.

关键词： Pharmacology of syndrome management system Data mining Qi and Yin deficiency syndrome Drug law

Correlation of BI-RADS grading with cancer cell proliferation and invasion

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Journal of Hainan Medical University 2018年第2期24卷 137-140页

作者： Guang-Rong Sun Xiao-Bo Zhao Min Yang Shu-Wen Chen Department of Ultrasound Guang’an District People’s Hospital in Guang’an City Sichuan ProvinceGuang’anSichuan Province648550China Department of Breast Surgery Affiliated Hospital of North Sichuan Medical CollegeNanchongSichuan Province638000China Department of Ultrasound Guang’an HospitalWest China HospitalSichuan UniversityGuang’anSichuan Province638000China

Objective:To investigate the correlation of BI-RADS grading with cancer cell proliferation and ***: A total of 138 patients who were diagnosed with breast cancer in our hospital between August 2015 and October 2017 were divided into 2 cases at stage Ⅲ, 51 cases at stage Ⅳ and 85 cases at stage Ⅴ after the BI-RADS grading was reviewed. Differences in the expression of proliferation-related genes and invasion-related genes were compared among the three groups of ***: Expressions of pro-proliferation genes MTA2, mTOR, PKM2, Notch1 and FSCN1 mRNA in lesion tissue of patients at stage Ⅴ and Ⅳ were higher than those of patients at stage Ⅲ whereas expressions of anti-proliferation genes BRCA1 and PTEN mRNA were lower than those of patients at stage Ⅲ;expressions of pro-invasion genes Gab2 and NUAK1 mRNA were higher than those of patients at stage Ⅲ whereas expressions of anti-invasion genes EBP50, edn3, FBXW7 and NDRG1 mRNA were lower than those of patients at stage Ⅲ. With the increase of BI-RADS grades, the expression levels of pro-proliferation genes and pro-invasion genes further increased while the expression levels of anti-proliferation and anti-invasion genes further decreased in the lesion ***: BI-RADS grading of patients with breast cancer is positively correlated with the proliferation and invasion activity of cancer cells.

关键词： Breast cancer BI-RADS grading Proliferation gene Invasion gene

Photonic-reconfigurable entanglement distribution network based on silicon quantum photonics

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Photonics Research 2023年第7期11卷 1314-1325页

作者： DONGNING LIU JINGYUAN LIU XIAOSONG REN XUE FENG FANG LIU KAIYU CUI YIDONG HUANG WEI ZHANG Frontier Science Center for Quantum Information Beijing National Research Center for Information Science and Technology(BNRist)Electronic Engineering DepartmentTsinghua UniversityBeijing 100084China Beijing Academy of Quantum Information Sciences Beijing 100193China

The entanglement distribution network connects remote users by sharing entanglement resources,which is essential for realizing quantum *** propose a photonic-reconfigurable entanglement distribution network(PR-edn)based on a silicon quantum photonic *** entanglement resources are generated by a quantum light source array based on spontaneous four-wave mixing in silicon waveguides and distributed to different users through time-reversed Hong–Ou–Mandel interference by on-chip Mach–Zehnder interferometers with thermo-optic phase shifters(TOPSs).A chip sample is designed and fabricated,supporting a PR-edn with3 subnets and 24 *** network topology of the PR-edn could be reconfigured in three network states by controlling the quantum interference through the TOPSs,which is demonstrated ***,a reconfigurable entanglement-based quantum key distribution network is realized as an application of the *** reconfigurable network topology makes the PR-edn suitable for future quantum networks requiring complicated network control and ***,it is also shown that silicon quantum photonic chips have great potential for large-scale PR-edn,thanks to their capacities for generating and manipulating plenty of entanglement resources.

关键词： quantum distribution topology

O(t^(-β))-SYNCHRONIZATION AND ASYMPTOTIC SYNCHRONIZATION OF DELAYED FRACTIONAL ORDER NEURAL NETWORKS

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Acta Mathematica Scientia 2022年第4期42卷 1273-1292页

作者： Anbalagan PRATAP Ramachandran RAJA Jinde CAO Chuangxia HUANG Jehad ALZABUT Ovidiu BAGDASAR Department of Mathematics Alagappa UniversityKaraikudi 630004India Ramanujan Centre for Higher Mathematics Alagappa UniversityKaraikudi 630004India School of Mathematics Southeast UniversityNanjing 211189China Yonsei Frontier Lab Yonsei UniversitySeoul03722South Korea Hunan Provincial Key Laboratory of Mathematical Modeling and Analysis in Engineering Changsha University of Science and TechnologyChangsha410114China Department of Mathematics and General Sciences Prince Sultan UniversityRiyadh 12435Saudi Arabia Department of Electronics Computing and MathematicsUniversity of DerbyUnited Kingdom

This article explores the O(t^(-β))synchronization and asymptotic synchronization for fractional order BAM neural networks(FBAMNNs)with discrete delays,distributed delays and non-identical *** designing a state feedback control law and a new kind of fractional order Lyapunov functional,a new set of algebraic sufficient conditions are derived to guarantee the O(t^(-β))Synchronization and asymptotic synchronization of the considered FBAMNNs model;this can easily be evaluated without using a MATLAB LMI control ***,two numerical examples,along with the simulation results,illustrate the correctness and viability of the exhibited synchronization results.

关键词： O(t^(-β))-synchronization asymptotic synchronization BAM neural networks fractional order state feedback control law

Genetics polymorphisms and atrial fibrillation susceptibility: a systematic review and meta-analysis

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South china Journal of Cardiology 2011年第1期12卷 56-64页

作者： ZHU Wa-li WU Wei-feng ZHU Li-guang ZHANG Hai-feng Department of Cardiology institute of Cardiovascular Diseases First Affiliated Hospital Guangxi Medical University Nanning GuangXi 530021 China

Background Atrial fibrillation （AF） was used to be considered as nongenetics disorder, but recent studies have revealed that genetics variants conferred susceptibility to AF development, but most with limited evidence. In order to systematically evaluate the overall contributions of gene-disease association studies to current understandings of the genetic susceptibility to atrial fibrillation, we perform a systematic review and meta- analysis based on comprehensive searches. Method All studies on the associations of genetics variants with AF risk were identified by searching the following databases： Medline, Embase, BIOSIS, Global Health, LILACS and CBMDisc. Odds ratios （CI） and 95 % confidence intervals （CI） were calculated under homozygote comparison （HC）, dominant model （DM） and recessive model （RM）, respectively. Results A total of 41 studies on 32 genes and 72 polymorphisms locations were identified. The summary OR was statistically significant associations in 23 （31.94 %） single nucleotide polymorphisms （SNPs）. The genes in renin-angiotensin- aldosterone system （RAAS） and ion channels were the mostly studied. Four SNPs （50.00 %） in RAAS genes were significantly associated with AF susceptibility： ACE I/D （HC. OR = 1.53, 95 % CI： 1.14-2.0 DM： OR = 1.47, 95 % CI： 0.86-1.53; RM： OR = 0.49, 95% CI： 0.41-0.59）; AGT A-20C （HC： OR = 1.56, 95 % CI. 1.41-2.12）; AGT M235T （HC： OR = 2.37, 95 % CI： 1.21-4.65）. Statistically significant associations were also found in the following genes and SNPs： ABCA1 G1051A, BCHE G1615A, CETP A1061G, I405V, TaqlB, CRP C1444T, edn2 A985G, eNOS T-786C, IL-10 T-819C, A-592C, MinK G38S, KCNH2 rs1805120, Kit 3.4 C171T, G810T, MMP2 C-1306T, Factor 11 G20210A, SCNSA H58R, SLC26A8 I639V, G-protein β- subunit C825T, chromatosome 4q25 rs2200733 and rs10033464. Conclusions Nearly one-third of SNPs were statistically significant associated with AF risk, with variants in RAAS genes most highly significant association. More studies on a wide range of

关键词： atrial fibrillation genetics polymorphisms susceptibility

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探讨适配器电源设计

电子设计技术 edn china 2010年第10期17卷 I0010-I0011页

作者： Jason Sun Fairchild Semiconductor China

1、介绍随着电子类产品在人们生活中越来越多的应用，而所有的电子类产品也都离不开电源，随之也带来了一些问题，如能源消耗和人身安全等等。各国对电源产品都有相应的法律要求，

关键词：适配器电源设计设计流程 Fairchild

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用MOS晶体管构成电流型施密特触发器

电子设计技术 1999年第6期 52-52页

作者： Tai-Shan Liao Chun-Ming Chang Wen-Yaw Chung Chung-Yuan Christian University Taiwan china Christian University Taiwan china Christian University Taiwan china Christian University Taiwan china

施密特触发器在模拟电路和数字电路中,可用来减少对噪声和干扰的灵敏度。电流型施密特触发器在光电检测器、条码阅读器和光学远距控制器中特别有用。图1中所示的这种无电阻器的电流型施密特触发器使用了6只晶体管。这种电路使用了一个... 详细信息

施密特触发器在模拟电路和数字电路中,可用来减少对噪声和干扰的灵敏度。电流型施密特触发器在光电检测器、条码阅读器和光学远距控制器中特别有用。图1中所示的这种无电阻器的电流型施密特触发器使用了6只晶体管。这种电路使用了一个倒相器的输出,并通过改变门限电流来获得反馈信号。本电路使用了一个倒相器对(QN2,Qp4,一个电流镜像对

关键词：晶体管 MOS 施密特触发器半导体三极管电流型倒相器

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DSL线路驱动器电路主动与被动匹配的应用

电子设计技术 2001年第10期 70-70页

作者：印宁华 Elantec Semiconductor Inc.china

目前DSL设备越来越趋于高密化,对于DSLAM用户来说,必须更好地优化DSL线路驱动器的性能和功耗。主动匹配模式(Active termination)正是这种既可降低线路驱动器功耗又能优化其性能的技术。本文在讨论主动匹配模式之前,首先简单分析和讨论... 详细信息

目前DSL设备越来越趋于高密化,对于DSLAM用户来说,必须更好地优化DSL线路驱动器的性能和功耗。主动匹配模式(Active termination)正是这种既可降低线路驱动器功耗又能优化其性能的技术。本文在讨论主动匹配模式之前,首先简单分析和讨论了单端驱动电

关键词：线路驱动器 DSL 正反馈电路

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用半占空比发生器连接两台仪器的CPLD

电子设计技术 edn china 2008年第1期15卷 114-114页

作者： Yu-Chieh Chen Tai-Shan Liao National Applied Research Laboratories HsinchuTaiwan China

当同步两台仪器的信号时，重要的是确保接收器可以锁存发送器的同步信号。例如，一台脉冲发生器会在生成主脉冲信号的同时产生同步脉冲。对Avtek的AV-1015B而言，在50Q负载的TIL下，脉冲发生器的占空比大约为50ns。本设计实例的目的是... 详细信息

当同步两台仪器的信号时，重要的是确保接收器可以锁存发送器的同步信号。例如，一台脉冲发生器会在生成主脉冲信号的同时产生同步脉冲。对Avtek的AV-1015B而言，在50Q负载的TIL下，脉冲发生器的占空比大约为50ns。本设计实例的目的是增加脉冲发生器的高电平宽度，以满足一个同步放大器的触发规定。同步脉冲的频率为10Hz～102kHz，这是同步放大器的频率范围。

关键词：脉冲发生器占空比 CPLD 仪器同步信号连接同步脉冲频率范围

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致读者

电子设计技术 1995年第1期 6-6页

作者：张未名电子设计技术END china 出版人

诸位读者, 你们好!1995年过去一半了,象学生的“期中考试“,我们奉上6月号的《电子设计技术edn china》。这一期杂志在版式设计上有一些改进,既是为读者翻阅查找各个栏目方便而考虑,也是为突出我们杂志的特色。在我国活跃的电子业,各种... 详细信息

诸位读者, 你们好!1995年过去一半了,象学生的“期中考试“,我们奉上6月号的《电子设计技术edn china》。这一期杂志在版式设计上有一些改进,既是为读者翻阅查找各个栏目方便而考虑,也是为突出我们杂志的特色。在我国活跃的电子业,各种期刊也是数不胜数,但据业内人士反映,内容质量高、读者覆盖面广的为技术开发

关键词：读者电子设计电子业

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