检索结果-南通市图书馆

Immediate intraocular pressure rise after intravitreal injection of ranibizumab and two doses of triamcinolone acetonide

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

International Journal of Ophthalmology(English edition) 2011年第4期4卷 402-405页

作者： Gul Arikan Ali Osman Saatci Ferit Hakan Oner Department of Ophthalmology School of Medicine Dokuz Eylul University

AIM: To evaluate prospectively immediate intraocular pressure (IOP) changes after the intravitreal injection of ranibizumab, 2 and 4mg triamcinolone acetonide. METHODS: Patients who underwent intravitreal injection of 0.1mL (4mg) triamcinolone acetonide (TA, Group T4), 0.05mL (2mg) TA (Group T2) and 0.05mL (0.5mg) ranibizumab (Group R) comprised the study population. Overall, 229 eyes of 205 patients were injected. Fifty-four eyes (23.6%) were in Group T4, 69 eyes (30.1%) in Group T2 and 106 eyes (46.3%) in Group R. If IOP was less than 26mmHg immediately after the injection no further measurement was performed. If IOP was ≥26mmHg, IOP was remeasured till the reading was below 26mmHg at 5, 15 and 30 minutes. RESULTS: Immediately after the injection, the IOP of 28 eyes (51.9%) in Group T4, 22 eyes (31.9%) in Group T2 and 51 eyes (48.1%) in Group R were over 25mmHg. At 30 minutes, IOP of one eye (1.9%) in group T4, two eyes (2.9%) in group T2 and two eyes (1.9 %) in Group R were over 25mmHg. Immediate post-injection IOP was significantly higher in Group T4 and Group R when compared to Group T2 (P <0.001 and P <0.001, respectively). IOP was significantly higher in eyes without vitreous reflux when compared to those with vitreous reflux in all groups (P <0.001). CONCLUSION: IOP may remarkably increase immediately after the intravitreal injection of 2 or 4mg triamcinolone acetonide, and 0.5mg ranibizumab. Absence of vitreous reflux is the most important predicting factor for immediate IOP rise after the injection.

关键词： anti-VEGF agents glaucoma intraocular pressure intravitreal injection steroids

Brain age estimation:premise,promise,and problems

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Neural Regeneration Research 2025年第8期20卷 2313-2314页

作者： Jarrad Perron Ji Hyun Ko Graduate Program in Biomedical Engineering Price Faculty of EngineeringUniversity of ManitobaWinnipegMBCanada PrairieNeuro Research Centre Kleysen Institute for Advanced MedicineHealth Sciences CentreWinnipegMBCanada Department of Human Anatomy and Cell Science Rady Faculty of Health SciencesUniversity of ManitobaWinnipegMBCanada

Premise:The com bined effects of modern healthcare practices which prolong lifespan and declining birthrates have created unprecedented changes in age demographics worldwide that are especially pronounced in Japan,South Korea,Europe,and North *** old age is the most significant predictor of dementia,global healthcare systems must rise to the challenge of providing care for those with neurodegenerative disorders.

关键词： estimation providing birth

Acquired sensorineural hearing loss,oxidative stress,and microRNAs

在线全文

学校读者我要写书评

暂无评论

Neural Regeneration Research 2025年第9期20卷 2513-2519页

作者： Desmond A.Nunez Ru C.Guo Division of Otolaryngology–Head&Neck Surgery Department of SurgeryFaculty of MedicineThe University of British ColumbiaVancouverBCCanada Division of Otolaryngology–Head&Neck Surgery Gordon&Leslie Diamond Health Care CentreVancouver General HospitalVancouverBCCanada faculty of Medicine–The university of British Columbia VancouverBCCanada

Hearing loss is the third leading cause of human ***-related hearing loss,one type of acquired sensorineural hearing loss,is largely responsible for this escalating global health ***-induced,ototoxic,and idiopathic sudden sensorineural are other less common types of acquired hearing *** etiology of these conditions is complex and multi-fa ctorial involving an interplay of genetic and environmental *** stress has recently been proposed as a likely linking cause in most types of acquired sensorineural hearing *** non-coding RNA sequences known as microRNAs(miRNAs)have increasingly been shown to play a role in cellular hypoxia and oxidative stress responses including promoting an apoptotic *** hair cell death is a central histopathological finding in sensorineural hearing *** these cells do not regenerate in humans,it underlies the irreversibility of human age-related hearing *** EMBASE,Ovid MEDLINE,Web of Science Core Collection,and *** databases over the period August 1,2018 to July 31,2023 were searched with"hearing loss,""hypoxamiRs,""hypoxia,""microRNAs,""ischemia,"and"oxidative stress"text words for English language primary study publications or registered clinical *** red clinical trials known to the senior author we re also assessed.A total of 222studies were thus *** excluding duplicates,editorials,retra ctions,secondary research studies,and non-English language articles,39 primary studies and clinical trials underwent full-text *** resulted in 11 animal,in vitro,and/or human subject journal articles and 8 registered clinical trial database entries which form the basis of this narrative *** miR-34a and miR-29b levels increase with age in *** miRNAs were demonstrated in human neuroblastoma and murine cochlear cell lines to target Sirtuin 1/peroxisome proliferato r-activated receptor gamma coactivator-1-alpha(SIRT1/P GC-1α),SIRT

关键词： hearing loss hypoxia microRNAs oxidative stress sensorineural

Navigating the pathways:TAR-DNA-binding-protein-43 aggregation,axonal transport,and local synthesis in amyotrophic lateral sclerosis pathology

在线全文

学校读者我要写书评

暂无评论

Neural Regeneration Research 2025年第10期20卷 2921-2922页

作者： Ori Bar Avi Eran Perlson Department of Physiology and Pharmacology Faculty of Medical&Health ScienceTel-Aviv UniversityTel-AvivIsrael Sagol School of Neuroscience Tel-Aviv UniversityTel-AvivIsrael

Neurons are highly polarized cells with axons reaching over a meter long in adult *** survive and maintain their proper function,neurons depend on specific mechanisms that regulate spatiotemporal signaling and metabolic events,which need to be carried out at the right place,time,and *** mechanisms include axonal transport,local synthesis,and liquid-liquid phase *** and malfunctions in these processes are correlated to neurodegenerative diseases such as amyotrophic lateral sclerosis(ALS).

关键词： synthesis local aggregation

Mechanisms behind elevated serum levels of plasminogen activator inhibitor-1 in frontotemporal lobar degeneration

在线全文

学校读者我要写书评

暂无评论

Neural Regeneration Research 2025年第8期20卷 2317-2318页

作者： Francesco Angelucci Jakub Hort Memory Clinic Department of NeurologySecond Faculty of MedicineCharles University and Motol University HospitalPragueCzech Republic International Clinical Research Centre St.Anne’s University HospitalBrnoCzech Republic

Frontotemporal lobar degeneration(FTLD)is a form of progressive dementia characterized by degeneration of the frontal and temporal lobes of the *** pathology involves a series of cognitive,behavioral,and neurological ... 详细信息

关键词： degeneration elevated pathology

A Two-Level Approach based on Integration of Bagging and Voting for Outlier Detection

在线全文

学校读者我要写书评

暂无评论

Journal of Data and Information Science 2020年第2期5卷 111-135页

作者： Alican Dogan Derya Birant The Graduate School of Natural and Applied Sciences Dokuz Eylul UniversityIzmirTurkey Department of Computer Engineering Dokuz Eylul UniversityIzmirTurkey

Purpose:The main aim of this study is to build a robust novel approach that is able to detect outliers in the datasets *** serve this purpose,a novel approach is introduced to determine the likelihood of an object to be extremely different from the general behavior of the entire ***/methodology/approach:This paper proposes a novel two-level approach based on the integration of bagging and voting techniques for anomaly detection *** proposed approach,named Bagged and Voted Local Outlier Detection(BV-LOF),benefits from the Local Outlier Factor(LOF)as the base algorithm and improves its detection rate by using ensemble ***:Several experiments have been performed on ten benchmark outlier detection datasets to demonstrate the effectiveness of the BV-LOF *** to the results,the BV-LOF approach significantly outperformed LOF on 9 datasets of 10 ones on *** limitations:In the BV-LOF approach,the base algorithm is applied to each subset data multiple times with different neighborhood sizes(k)in each case and with different ensemble sizes(T).In our study,we have chosen k and T value ranges as[1-100];however,these ranges can be changed according to the dataset handled and to the problem *** implications:The proposed method can be applied to the datasets from different domains(***,finance,manufacturing,etc.)without requiring any prior *** the BV-LOF method includes two-level ensemble operations,it may lead to more computational time than single-level ensemble methods;however,this drawback can be overcome by parallelization and by using a proper data structure such as R*-tree or ***/value:The proposed approach(BV-LOF)investigates multiple neighborhood sizes(k),which provides findings of instances with different local densities,and in this way,it provides more likelihood of outlier detection that LOF may *** also brings many benefits such as easy impleme

关键词： Outlier detection Local outlier factor Ensemble learning Bagging Voting

Polymer Film Supported Bimetallic Au–Ag Catalysts for Electrocatalytic Oxidation of Ammonia Borane in Alkaline Media

在线全文

学校读者我要写书评

暂无评论

Nano-Micro Letters 2016年第4期8卷 358-370页

作者： Sukriye Ulubay Karabiberoglu Cagri Ceylan Kocak Suleyman Kocak Zekerya Dursun Department of Chemistry Science FacultyEge University Occupational Health and Safety Department Bergama Vocational SchoolDokuz Eylul University Department of Chemistry Science and Art FacultyCelal Bayar University

Ammonia borane is widely used in most areas including fuel cell *** present paper describes electrochemical behavior of ammonia borane in alkaline media on the poly(p-aminophenol) film modified with Au and Ag bimetallic *** glassy carbon electrode was firstly covered with polymeric film electrochemically and then,Au,Ag,and Au–Ag nanoparticles were deposited on the polymeric film,*** surface morphology and chemical composition of these electrodes were examined by scanning electron microscopy,transmission electron microscopy,electrochemical impedance spectroscopy,X-ray diffraction,and X-ray photoelectron *** was found that alloyed Au–Ag bimetallic nanoparticles are *** measurements indicate that the developed electrode modified by Au–Ag bimetallic nanoparticles exhibit the highest electrocatalytic activity for ammonia borane oxidation in alkaline *** rotating disk electrode voltammetry demonstrates that the developed electrode can catalyze almost six-electron oxidation pathway of ammonia *** results may be attractive for anode materials of ammonia borane fuel cells under alkaline conditions.

关键词： Au-Ag bimetallic nanoparticles Ammonia borane Electrocatalyst Electropolymerization Alkaline media

What is the relationship between frailty and orthostatic hypotension in older adults?

在线全文

学校读者我要写书评

暂无评论

Journal of Geriatric Cardiology 2019年第3期16卷 272-279页

作者： Suleyman Emre Kocyigit Pinar Soysal Esra Ates Bulut Ali Ekrem Aydin Ozge dokuzlar Ahmet Turan Isik Unit for Aging Brain and Dementia Department of Geriatric MedicineFaculty of MedicineDokuz Eylul UniversityIzmirTurkey Department of Geriatric Medicine Bezmialem Vakif UniversityFaculty of MedicineIstanbulTurkey

Background Frailty and orthostatic hypotension (OH),which is common in older adults,is associated with morbidity and *** relationship between them remains *** aim of the study is to determine whether there is a relationship between frailty and *** A total of 496 patients who were admitted to the geriatric clinic and underwent comprehensive geriatric assessment were retrospectively *** a cross-sectional and observational study,OH was measured by the Head-up Tilt Table test at 1,3,and 5 min (respectively,OH1,OH3,and OH5) and the frailty was measured by the Fried’s frailty *** The mean age of all patients was 75.4 ± *** prevalence of females was 69.8%.When the frail people were compared with the pre-frail and the robust ones,the frailty was associated with *** was no relationship between the groups in terms of OH1 when the pre-frail group was compared with the robust ***3 were higher in the frail group than in the pre-frail group (P 0.05).Slowness and weakness were associated with OH1 (P < 0.05),whereas the other components of the Fried’s test were *** Frailty may be a risk factor for *** 1^st min measurements of OH should be routinely evaluated in frail older adults to prevent OH-related poor outcomes.

关键词： Frail Orthostatic hypotension Pre-frail Robust

Market Drivers in India’s Smart Grid:Responsibilities and Roles of Stakeholders

在线全文

学校读者我要写书评

暂无评论

Energy Engineering 2025年第1期122卷 101-128页

作者： Abhay Sanatan Satapathy Suresh Kumar Sahoo Asit Mohanty Yasser Fouad Manzoore ElahiMohammad Soudagar Erdem Cuce faculty of Management Studies Sri Sri UniversityCuttack754006India Institute of Power Engineering National Energy UniversityJalan Ikram-UnitenKajangSelangor43000Malaysia Centre of Research Impact and Outcome Chitkara UniversityRajpura140417PunjabIndia Department of Applied Mechanical Engineering College of Applied EngineeringMuzahimiyah BranchKing Saud UniversityRiyadh11421Saudi Arabia College of Engineering Lishui UniversityLishui323000China Department of Mechanical Engineering Graphic Era(Deemed to be University)Dehradun248002UttarakhandIndia Department of Mechanical Engineering Faculty of EngineeringUniversity of MalayaKuala Lumpur50603Malaysia Department of Mechanical Engineering Faculty of Engineering and ArchitectureRecep Tayyip Erdogan UniversityZihni Derin CampusRize53100Turkey Center for Research Impact&Outcome Chitkara UniversityRajpura140401PunjabIndia university Centre for Research and Development Chandigarh UniversityMohali140413PunjabIndia

The emergence of smart grids in India is propelled by an intricate interaction of market dynamics,regulatory structures,and stakeholder *** study analyzes the primary factors that are driving the widespread use of smart grid technologies and outlines the specific roles and obligations of different stakeholders,such as government entities,utility companies,technology suppliers,and *** activities and regulations are crucial in facilitating the implementation of smart grid technology by offering financial incentives,regulatory assistance,and strategic *** firms have the responsibility of implementing and integrating smart grid infrastructure,with an emphasis on improving the dependability of the grid,minimizing losses in transmission and distribution,and integrating renewable energy *** companies offer the essential hardware and software solutions,which stimulate creativity and enhance *** actively engage in the energy ecosystem by participating in demand response,implementing energy saving measures,and adopting distributed energy resources like solar panels and electric *** study examines the difficulties and possibilities in India’s smart grid industry,highlighting the importance of cooperation among stakeholders to build a strong,effective,and environmentally friendly energy future.

关键词： Smart grid stakeholders smart grid technology market drivers