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Accuracy Evaluation of A Diagnostic Test by Detecting Outliers and Influential Observations

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China Ocean Engineering 2008年第3期22卷 421-429页

作者： Hsien-Chueh Peter YANG Tsung-Hao CHEN Cheng-Wu CHEN Chen-Yuan CHEN Chun-Te LIU Department of Risk management and Insurance National Knohsiung First University of Science and Technology Kaohsiung 811 China Department of Business Administration Shu-Te University Kaohsiung 82445 China Department of Logistics management Shu-Te University Kaohsiung 82445 China Department of management Information System Yung- Ta Institute of Technology and Commerce Pingtung 90941 China doctoral program in management National Kaohsiung First University of Science and Technology Kaohsiung 811 China

Logit regression analysis is widely applied in scientific studies and laboratory experiments, where skewed observations on a data set are often encountered. A number of problems with this method, for example, oudiers and influential observations, can cause overdispersion when a model is fitted. In this study a systematic statistical approach, including the plotting of several indices is used to diagnose the lack-of-fit of a logistic regression model. The outliers and influential observations on data from laboratory experiments are then detected. Specifically we take account of the interaction of an internal sohtary wave （ISW） with an obstacle, i.e., an underwater ridge, and also analyze the effects of the ridge height, the lower layer water depth, and the potential energy on the amplitude-based transmission rate of the ISW. As concluded, the goodness-of-fit of the revised logit regression model is better than that of the model without this approach.

关键词： diagnostic testing outliers influential observations internal solitary wave

New drug delivery system for liver sinusoidal endothelial cells for ischemia-reperfusion injury

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World Journal of Gastroenterology 2015年第45期21卷 12778-12786页

作者： Naoki Sano Takafumi Tamura Naoyuki Toriyabe Takeshi Nowatari Ken Nakayama Tomohito Tanoi Soichiro Murata Yu Sakurai Mamoru Hyodo Kiyoshi Fukunaga Hideyoshi Harashima Nobuhiro Ohkohchi Department of Surgery Doctoral Program in Clinical Science Graduate School of Comprehensive Human Sciences University of Tsukuba Faculty of Pharmaceutical Sciences Hokkaido University

AIM: To investigate the cytoprotective effects in hepatic ischemia-reperfusion injury, we developed a new formulation of hyaluronic acid(HA) and sphingosine ***: We divided Sprague-Dawley rats into 4 groups: control, HA, sphingosine 1-phosphate(S1P), and HA-S1 P. After the administration of each agent, we subjected the rat livers to total ischemia followed by reperfusion. After reperfusion, we performed the following investigations: alanine aminotransferase(ALT), histological findings, Td T-mediated d UTP-biotin nick end labeling(TUNEL) staining, and transmission electron microscopy(TEM). We also investigated the expressionof proteins associated with apoptosis, hepatoprotection, and S1 P accumulation. RESULTS: S1 P accumulated in the HA-S1 P group livers more than S1 P group livers. Serum ALT levels, TUNEL-positive hepatocytes, and expression of cleaved caspase-3 expression, were significantly decreased in the HA-S1 P group. TEM revealed that the liver sinusoidal endothelial cell(LSEC) lining was preserved in the HA-S1 P group. Moreover, the HA-S1 P group showed a greater increase in the HO-1 protein levels compared to the S1 P ***: Our results suggest that HA-S1 P exhibits cytoprotective effects in the liver through the inhibition of LSEC apoptosis. HA-S1 P is an effective agent for hepatic ischemia/reperfusion injury.

关键词： Hyaluronic acid Sphingosine 1-phosphate Liver sinu

Profile Evolution and Energy Dissipation for Internal SolitonTransmitting over Different Submarine Ridges

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China Ocean Engineering 2006年第4期20卷 585-594页

作者： Chen-Yuan CHEN I-Fan TSENG Hsien-Chueh Peter YANG Cheng-Wu CHEN Tsung-Hao CHENe Department of management Information System Yung-Ta Institute of Technologyand Commerce Ping Tung County 90941 Center for Marine Technology National Sun Yat-sen University Kaohsiung 80424 Department of Risk management and Insurance National Kaohsiung FirstUniversity of Science and Technology Kaohsiung County 811 Taiwan China Department of Logistics management Shu-Te University Yen Chau Kaohsiung 82445 Taiwan China doctoral program in management National Kaohsiung First University of Scienceand Technology Kaohsiung County 811 Taiwan China

Fundamental experiments were carried out in a wave flume on internal solitary wave （ISW） of depression-type propagating over a submerged ridge. The seabed ridge included either triangular or semicircular shape - regarded as topographic obstacles. Influenced by the submarine ridge, the transmitted waves were found to always consist of a leading pulse （a solitary wave） followed by a dispersive wave train. The wave profile propagating over a triangular ridge was similar to that caused by a semicircular obstacle. Apparently, the smooth face of a semicircular ridge produced time lag of wave propagation. From experimental results available, the reduction in wave energy induced by a semicircular ridge was larger than that by a triangular one. The events of wave distortion, strong breaking, internal bolus, and stratification mixing happened in case that the crest of an ISW was great enough to interact with the topographic obstacle. The reduction in wave energy was induced by strong breaking, and it depended on the ridge height rather than the geometric shape of the ridge.

关键词： ridge height wave breaking internal solitary wave energy dissipation wave flume laboratory

EVALUATING TWO RAINWATER HARVESTING SYSTEMS IN AN URBAN SETTING IN OREGON'S WILLAMETTE VALLEY

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Journal of Green Building 2017年第1期12卷 1-10页

作者： Conner Olsen Alexander Kowalewski Micah Gould John Lambrinos Department of Horticulture Turfgrass Management ProgramOregon State UniversityCorvallisOR 97331-7304

INTRODUCTION The recent trend toward more extreme periods of drought has been a shock to the residents of the Pacific Northwest-many of whom have relied upon heavy water-use in the summer months in order to make a living(*** of grass seed and sod,berries,or nursery crops),or to maintain their landscapes at high levels(*** homeowners,recreational facilities,or commercial properties).Further-more,population growth has reached the point where even an average year of pre-cipitation has proven insufficient for urbanities that had not previously experienced issues with water scarcity(McDonald et al.,2011).This modern climate scenario has forced people of the Pacific Northwest,and people from all around the world,to rethink their water-use strategies,as the global trend has shifted toward greater sustainability(Tilman,2001;McDonald et al.,2011).

关键词： rainwater-harvesting system subsurface matrix storage cistern pedal-powered pump

Do natural resources impact economic growth:An investigation of P5+1 countries under sustainable management

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Geoscience Frontiers 2024年第3期15卷 192-208页

作者： Sanjeet Singh Gagan Deep Sharma Magdalena Radulescu Daniel Balsalobre-Lorente Pooja Bansal University Centre for Research and Development Chandigarh UniversityGharuanMohaliPunjabIndia University School of management Studies Guru Gobind Singh Indraprastha UniversityDwarkaDelhiIndia Department of Finance Accounting and EconomicsUniversity of PitestiPitesti 110040Romania Institute for doctoral and Post-doctoral Studies University“Lucian Blaga”SibiuSibiu 550024Romania Department of Applied Economics I University of Castilla-La ManchaSpain Department of management Faculty of Economics and ManagementCzech University of Life Sciences PraguePrague 16500Czech Republic

Natural resources represent the base of our living and the entire economic *** depletion is a major challenge for the economic development of both developed and developing *** effi-cient use is an indispensable requirement and must be the aim of the public policies designed by the authorities *** this research,we have investigated the impact of the natural resources rent on the economic growth in some major wealthy economies of the world(P5+1 countries namely:US,UK,France,China,Russia,and Germany).We have applied a quantile-on-quantile regression to analyse this impact on different quantiles and a cross-sectional autoregressive distributed lag(CS-ARDL)approach for the panel of these six *** Dumitrescu-Hurlin panel causality test was also used to check the causality between natural resource rents and economic growth in these *** show a negative relationship between natural resources rent and economic growth for the panel but a different impact on quantiles in each *** for China and the US,a positive effect can be noticed for both lower and higher quantiles of natural resources and economic *** Dumitrescu-Hurlin causality test shows that natural resources can predict economic growth only in China,the U.S.,and the *** contrast,no causality was found for the other four countries included in the *** suggest that nations invest in wind and solar projects,use biofuels and nuclear energy,introduce a temporary profit tax to protect consumers from escalating energy prices,and increase energy efficiency in buildings and *** would benefit from a regulatory framework that is uniform and exhaustive,as well as easier to traverse and more receptive to innovation and ***-private partnership investments in innovation,innovation incentives,and environmental sector opportunities may foster long-term economic growth。

关键词： Natural resources rent Economic growth Quantile-on-quantile regression Cross-sectional ARDL P5+1 countries

An Extended Fuzzy-DEMATEL System for Factor Analyses on Social Capital Selection in the Renovation of Old Residential Communities

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Computer Modeling in Engineering & Sciences 2023年第2期134卷 1041-1067页

作者： Guoshuai Sun Xiuru Tang Shuping Wan Jiao Feng School of Economics and management Liaoning University of TechnologyJinzhou121001China School of Information management Jiangxi University of Finance and EconomicsNanchang330032China Post-doctoral Research Center Zhongda Construction Co.Ltd.Guangzhou510280China School of Maritime Economics and management Dalian Maritime UniversityDalian116026China

China has been promoting the renovation of old residential communities *** to the financial pressure of the government and the sustainability of the renovation of old residential communities,public-private partnerships(PPP)have already gained *** selection of social capital is key to improving the efficiency of the PPP model in renovating old residential *** order to determine the influencing factors of social capital selection in the renovation of old residential communities,this paper aims to find an effective approach and analyze these *** this paper,a fuzzy decision-making and trial evaluation laboratory(fuzzy-DEMATEL)technique is extended and amore suitable systemis developed for the selection of social capital using the existing group decisionmaking *** the first stage,grounded theory is used to extract the unabridged key influencing factors for social capital selection in the renovation of old residential ***,by considering the impact of expert weights,the key influencing factors are *** interactions within these influencing factors are discussed and the credibility of the results is verified by sensitivity ***,these key influencing factors are sorted by *** on the results,the government should focus on a technical level,organizationalmanagement abilities,corporate reputation,credit status,*** study provides the government with a theoretical basis and a methodology for evaluating social capital selection.

关键词： Social capital selection fuzzy-DEMATEL influencing factors renovation of old residential communities grounded theory

Exploring genes that control microglial heterogeneity and transition

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Neural Regeneration Research 2021年第12期16卷 2397-2398页

作者： Tomomi Okajima Fuminori Tsuruta Graduate School of Life and Environmental Sciences University of TsukubaTsukubaIbarakiJapan Master’s and doctoral programs in Biology Faculty of Life and Environmental SciencesUniversity of TsukubaTsukubaIbarakiJapan Master’s and doctoral program in Neuroscience Graduate School of Comprehensive Human SciencesUniversity of TsukubaTsukubaIbarakiJapan PhD program in Human Biology School of Integrative and Global MajorsUniversity of TsukubaTsukubaIbarakiJapan PhD program in Humanics School of Integrative and Global MajorsUniversity of TsukubaTsukubaIbarakiJapan

Microglia,which comprise approximately 10%of total cells in the brain,are the resident immune cells in the central nervous system and contribute to maintaining the brain homeostasis through monitoring their microenvironment(Kettenmann et al.,2011).Recent studies have reported that microglia also regulate neural circuit formation after *** functional transition in microglia has been considered to correlate with their morphological changes over time.

关键词： al. homeostasis transition

Therapeutic effect of Guijiajiao(Colla Carapacis et Plastri) on bone regeneration in rats and zebrafish

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Journal of Traditional Chinese Medicine 2018年第2期38卷 197-210页

作者： Su Weiyang Feng Chienwei Tseng Chungchih Hung Hanchun Chen Zhicheng Lee Hsinpai Jean Yenhsuan Wu Shingyi Sean Wen Zhihong Department of Marine Biotechnology and Resources National Sun Yat-Sen University Division of Dentistry Zuoying Branch of Kaohsiung Armed Forces General Hospital doctoral Degree program in Marine Biotechnology Academia Sinica doctoral Degree program in Marine Biotechnology National Sun Yat-Sen University The School of Chinese Medicine for Post Baccalaureate I Shou University Section of Orthopedic Surgery PingtungChristian Hospital Section of Orthopedic Surgery Pingtung Christian Hospital

OBJECTIVE:To investigate the effect of Guijiajiao(Colla Carapacis et Plastri, CCP), the glue of tortoise shell, on bone regeneration in zebrafish and male Wistar ***: In this study, we applied in vitro and in vivo models, tissue section analysis, and quantitative polymerase chain reaction to assess the effects of CCP on bone repair. MG-63 cells were used in alkaline phosphatase(ALP) activity and mineralization assays. Zebrafish and male Wistar rats were used to evaluate the effects of CCP on bone repair in ***: A simple preparation of CCP promoted osteogenesis in vivo and in vitro, and promoted MG-63 cell proliferation as well as ALP activity and mineralization. In addition, CCP activated Akt and extracellular signaling-regulated kinase pathways and significantly increased the expression of ossification-related genes and proteins such as runt-related transcription factor-2, osteocalcin, and osteopontin. The in vivo results revealed promotion of osteogenesis by immersing zebrafish in CCP for 72 *** oral dose of 1.25 g/kg CCP significantly improved skull defects in rats, which was accompanied by an increase in serum ALP ***: One of the ingredients of Guilu Erxianjiao(tortoise shell and deer horn formula) pro-vides a practical alternative therapy for bone regeneration.

关键词： Colla Carapacis et Plastri Testudinis Bone regeneration Alkaline phosphatase Rat Zebrafish

Emergence and Development of Health Risk Communication Networks Among Street-Level Health Bureaucrats During the COVID-19 Pandemic Crisis in Myanmar

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International Journal of Disaster Risk Science 2022年第4期13卷 507-520页

作者： Thein Myomin Seunghoo Lim Public management and Policy Analysis program Graduate School of International RelationsInternational University of JapanMinamiuonumaNiigata 949-7277Japan

Street-level health bureaucrats have actively contributed to implementing the COVID-19 prevention,control,and treatment policies of the Myanmar ***,the need for bureaucrats on the frontlines of policy implementation to maintain a safe distance from others to prevent the spread of COVID-19 has posed challenges for the sharing and exchange of information related to health *** this context,this study examined what health risk communication patterns have emerged and developed among streetlevel health bureaucrats during the COVID-19 pandemic,and how this risk communication has been affected by streetlevel health bureaucrats'perceptions of client meaningfulness and willingness to implement COVID-19 *** results reveal that street-level health bureaucrats in the health risk communication network are embedded in reciprocally or transitively connected discussion relationships that sustain their health risk communication over ***,when specific healthcare staffmembers perceive more benefits of COVID-19 policies for their patients and are more willing to care for patients,other healthcare staffavoid them to protect themselves from COVID-19 *** to their higher level of understanding of the adopted measures,healthcare staffmembers who are highly willing to implement COVID-19 policies are frequently approached by other staffmembers to communicate about COVID-19 *** study empirically contributes to the literature on street-level bureaucrats in times of pandemic crisis by examining the formation of health risk communications in the context of street-level health bureaucrats'responses to and participation in public healthcare policy implementation processes.

关键词： Client meaningfulness COVID-19 crisis Health risk communication Social network analysis Street-level bureaucrats Willingness to implement policy