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Changing Proportions of HIV-1 Subtypes and Transmitted Drug Resistance Among Newly Diagnosed HIV/AIDS Individuals—China,2015 and 2018

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China CDC weekly 2021年第53期3卷 1133-1138页

作者： Jingjing Hao Shan Zheng Mengze Gan Aobo Dong Ruihua Kang Miaomiao Li Shuai Zhao Jing Hu Chang Song Lingjie Liao Yi Feng Yiming Shao Yuhua Ruan Hui Xing State Key Laboratory of infectious disease Prevention and control(SKLID) National Center for AIDS/STD Control and Prevention(NCAIDS)Chinese Center for Disease Control and Prevention(China CDC)Collaborative Innovation Center for Diagnosis and Treatment of Infectious DiseasesBeijingChina.

Introduction:With the expansion of human immunodeficiency virus(HIV)antiretroviral therapy(ART),HIV drug resistance is becoming more and more *** study describes the changing prevalence of HIV-1 subtypes and transmitted drug resistance(TDR)among newly diagnosed individuals in China,2015 and ***:A total of 8,980 individuals in 2015 and 2018 from 31 provincial-level administrative divisions(PLADs)were enrolled in this *** RNAs were amplified and sequenced using an in-house polymerase chain reaction(PCR)*** Stanford HIV Drug Resistance Database(HIVdb)was used to predict susceptibility to 12 antiretroviral ***:The prevalence of TDR was not significantly increased over *** prevalence of TDR was 3.8%and 4.4%in 2015 and 2018,respectively(P=0.13).The prevalence of CRF55_01B increased from 2.3%in 2015 to 3.9%in 2018(Pcontrol the transmission of HIV drug resistance.

关键词： drugs Stanford HIV/AIDS

Epidemiological Characteristics of Human Anthrax-China,2018-2021

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China CDC weekly 2022年第35期4卷 783-787页

作者： Huijuan Zhang Enmin Zhang Mu Guo Jinrong He Wei Li Jianchun Wei National Institute for Communicable disease control and Prevention Chinese Center for Disease Control and PreventionBeijingChina State Key Laboratory of infectious disease Prevention and control BeijingChina Yunnan Institute for Endemic disease control and Prevention Dali CityYunnan ProvinceChina

Introduction:The epidemic of human anthrax is at a low level in China in recent years,but the reported incidence increased in *** order to understand the current landscape of research and knowledge about anthrax in China,the epidemiological characteristics of anthrax in humans from 2018 to 2021 were analyzed and the prevention and control suggestions were ***:Surveillance data of anthrax in humans and livestock,together with human outbreaks data during 2018-2021,were collected and analyzed by descriptive statistics *** number and proportion of outbreaks,cases and deaths by provincial-level administrative divisions(PLADs),clinical types,and contributing factors were ***:A total of 1,244 cases of human anthrax and 53 outbreaks were reported from 2018 to 2021 in *** the incidence of anthrax declined from 2018 to 2020,it increased in *** regions of anthrax were mainly located in the west and the northeast PLADs of China,though cases were reported in some central and eastern PLADs in *** and middle-aged men involved in animal husbandry were found to be at a higher risk of *** the reported outbreaks were associated with the exposure of infected livestock.A total of 296 livestock anthrax cases were ***:The increased incidence and wider geographical distribution of human anthrax in 2021 were found to be the result of inadequate supervision of diseased animals as well as updated diagnostic *** such,the monitoring of risk factors and emergency preparation procedures should be strengthened at the national *** addition,it is also critical to strengthen health education for high-risk occupational groups and strengthen professional training for local ***,more measures should be carried out to strengthen anthrax surveillance in livestock husbandry.

关键词： prevention husbandry strengthened

Transmission Dynamics and Epidemiological Characteristics of the SARS-CoV-2 Delta Variant ― Hunan Province, China, 2021

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China CDC weekly 2023年第3期5卷 56-62,I0006-I0009页

作者： Kaiwei Luo Yanpeng Wu Yan Wang Ziyan Liu Lan Yi Shanlu Zhao Xuemei Yan Hao Yang Kaiyuan Sun Marco Ajelli Shixiong Hu Hongjie Yu Hunan Provincial Center for disease control and Prevention Workstation for Emerging Infectious Disease Control and PreventionChinese Academy of Medical SciencesChangsha CityHunan ProvinceChina Shanghai Institute of infectious disease and Biosecurity Fudan UniversityShanghai MunicipalityChina School of Public Health Fudan UniversityKey Laboratory of Public Health SafetyMinistry of EducationShanghai MunicipalityChina Division of International epidemiology and Population Studies Fogarty International CenterNational Institutes of HealthBethesdaMDUSA Laboratory of Computational epidemiology and Public Health Department of Epidemiology and BiostatisticsIndiana University School of Public HealthBloomingtonINUSA

Monitoring changes in the epidemiologic features between different severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)variants is key to understanding the evolution of viral fitness in the host ***,we analyzed a successfully contained local outbreak of the Delta variant that took place in Hunan,China,in July–August,*** data on SARS-CoV-2 infections and their contacts were collected during the *** leveraging these data,we estimated key epidemiological parameters,including the incubation period,serial interval,and generation *** constructed a generalized linear mixed-effects model(GLMM)to quantify risk factors for Delta infection and *** July 28 and August 15,2021,a total of 129 infections and their 2,118 close contacts were identified during the outbreak in Hunan Province.

关键词： Hunan population Province

Pathogen genomic surveillance elucidates the origins, transmission and evolution of emerging viral agents in China

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Science China(Life Sciences) 2017年第12期60卷 1317-1330页

作者： Weifeng Shi Juan Li Hong Zhou George F.Gao Key Laboratory of Etiology and epidemiology of Emerging infectious diseases in Universities of Shandong (Taishan Medical College) Taishan Medical College National Institute for Viral disease control and Prevention Chinese Center for Disease Control and Prevention (China CDC) CAS Key Laboratory of Pathogenic Microbiology and Immunology Institute of Microbiology Chinese Academy of Sciences

In the past twenty years, numerous novel zoonotic viral agents with pandemic potential have emerged in China, such as the severe acute respiratory syndrome(SARS) coronavirus and, more recently, the avian-origin influenza A/H7N9 virus, which have caused outbreaks among humans with high morbidity and mortality. In addition, several emerging and re-emerging viral pathogens have also been imported into China from travelers, e.g. the Middle East respiratory syndrome(MERS) coronavirus and Zika virus(ZIKV). Herein, we review these emerging viral pathogens in China and focus on how surveillance by pathogen genomics has been employed to discover and annotate novel pathogenic agents, identify natural reservoirs, monitor the transmission events and delineate their evolution and adaption to the human host. We also highlight the application of genomic sequencing in the recent Ebola epidemics in Western Africa. In summary, genomic sequencing has become a standard research tool in the field of emerging infectious diseases which has been proven invaluable in containing these viral infections and reducing burden of disease in humans and animals. Genomic surveillance of pathogenic agents will serve as a key epidemiological and research tool in the modern era of precision infectious diseases and in the future studies of virosphere.

关键词： emerging infectious diseases SARS-CoV MERS-CoV genomic surveillance H7N9 Zika Ebola

An Outbreak of Febrile Histoplasmosis Among Chinese Manganese-Mine Workers in Cooperative Republic of Guyana in 2019

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China CDC weekly 2019年第3期1卷 38-42页

作者： Lei Zhou Xin Wang Jiandong Li Rui Song Xiaoping Dong George F.Gao Zijian Feng Public Health Emergency Center Chinese Center for Disease Control and PreventionBeijingChina Department of epidemiology and Biostatistics School of Public HealthPeking University Health Science CenterBeijingChina National Institute for Communicable disease control and Prevention Chinese Center for Disease Control and PreventionBeijingChina Institute for Viral disease control and Prevention Chinese Center for Disease Control and PreventionBeijingChina Beijing Ditan Hospital Capital Medical UniversityBeijingChina Global Public Health Center Chinese Center for Disease Control and PreventionBeijingChina State Key Laboratory for infectious disease Prevention and control Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases(Zhejiang University)National Institute for Viral Disease Control and PreventionChinese Center for Disease Control and PreventionBeijingChina Chinese Center for disease control and Prevention BeijingChina

Summary What is already known on this topic?Cases of histoplasmosis have been reported in every continent except Antarctica but are fairly rare in *** prevalence of histoplasmosis has been observed in Central America,Caribbean,and South *** of Histoplasma are acquired through a respiratory route,particularly inhalation of aerosols from disturbed soils enriched with excreta from birds and bats.

关键词： China soils disturbed

A Comparison of Clinical Characteristics of Infections with SARS-CoV-2 Omicron Subvariants BF.7.14 and BA.5.2.48-China,October-December 2022

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China CDC weekly 2023年第23期5卷 511-515页

作者： Da Huo Tong Yu Ying Shen Yang Pan Fu Li Shujuan Cui Bing Lyu Zhichao Liang Daitao Zhang Peng Yang Quanyi Wang Yue Sun Zhaomin Feng Institute for infectious disease and Endemic disease control Beijing Center for Disease Prevention and ControlBeijingChina School of Public Health Capital Medical UniversityBeijingChina Beijing Municipal Key Laboratory of Clinical epidemiology BeijingChina Beijing Office of Center for Global Health Beijing Center for Disease Prevention and ControlBeijingChina Respiratory and Critical Care Department Beijing Shijitan HospitalCapital Medical UniversityBeijingChina

Summary What is already known about this topic?Severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)continues to evolve,the clinical manifestations resulting from different SARS-CoV-2 variants may demonstrate significant *** is added by this report?We conducted a comparative analysis of the clinical features associated with SARS-CoV-2 Omicron subvariants BF.7.14 and BA.5.2.48 *** results of our study indicate that there are no substantial differences in clinical manifestations,duration of illness,healthcare-seeking behaviors,or treatment between these two *** are the implications for public health practice?Timely identification of alterations in the clinical spectrum is crucial for researchers and healthcare practitioners in order to enhance their comprehension of clinical manifestations,as well as the progression of ***,this information is beneficial for policymakers in the process of revising and implementing appropriate countermeasures.

关键词： alterations acute respiratory

Investigation of Brucellosis Caused by Raw Goat Milk—Fujian Province,China,April–June,2019

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China CDC weekly 2021年第20期3卷 430-433页

作者： Mu Di Zhongfa Tao Weiping Hua Jiandong Chen Jingming Cao Yanqin Deng Huihui Liu Lijie Zhang Yishan Chen Qiulan Chen Wenwu Yin Chinese Center for disease control and Prevention Infectious Diseases Management OfficeBeijingChina China Chinese Field epidemiology Training Project BeijingChina Guizhou Provincial Center for disease control and Prevention GuiyangGuizhouChina Zhangping County Center for disease control ZhangpingFujianChina Fujian Provincial Center for disease control and Prevention FuzhouFujianChina Emory University AtlantaUSA.

Summary What is already known about this topic?Brucellosis is one of the most important zoonotic diseases in *** milk and dairy products are essential pathways for foodborne transmission of *** can completely kill Brucella *** milk,and milk-borne transmission is mainly related to unhealthy dietary hygiene habits and insufficient epidemic control among animals.

关键词： China. Fujian Pasteur

Incidence Tendency Analysis on Type 2 Diabetes in 4 Asian Countries—China,Malaysia,Singapore,and Thailand,1990–2019

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China CDC weekly 2021年第52期3卷 1113-1117页

作者： Wenhui Shi Qiqi Wang Jiaojiao Zhang Jingwen Zhang Feng Tan Shicheng Yu Division of Non-communicable diseases and Elderly Health Management Chinese Center for Disease Control and PreventionBeijingChina Office of epidemiology Chinese Center for Disease Control and PreventionBeijingChina Institute of infectious diseases Beijing Center for Disease Control and PreventionBeijingChina Shijiazhuang Finance Bureau of Hebei Province ShijiazhuangHebeiChina Division of Academic Publishing Management Chinese Center for Disease Control and PreventionBeijingChina.

Summary What is already known about this topic?Roughly 80%of the global disease burden caused by diabetes comes from low-and-middle income countries,and 60%of diabetics are located in Asia;6 of the top 10 countries with the highest prevalence of diabetes are in *** is added by this report?Compared with 1990,the growth rate of the standardized incidence rate of type 2 diabetes in 2019 in China was significantly lower than that of the entire world,while Malaysia,Singapore.

关键词： Diabetes income Singapore

Genomic Characterization of a New Coronavirus from Migratory Birds in Jiangxi Province of China

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Virologica Sinica 2021年第6期36卷 1656-1659页

作者： Wentao Zhu Wentao Song Guoyin Fan Jing Yang Shan Lu Dong Jin Xue-lian Luo Ji Pu Haiying Chen Jianguo Xu State Key Laboratory of infectious disease Prevention and control National Institute for Communicable Disease Control and PreventionChinese Center for Disease Control and PreventionBeijing 102206China The Collaboration Unit for Field epidemiology of State Key Laboratory of infectious disease Prevention and control Jiangxi Provincial Key Laboratory of Animal-Origin and Vector-Borne DiseasesNanchang Center for Disease Control and PreventionNanchang 330038China Shanghai Public Health Clinical Center Fudan UniversityShanghai 201508China Research Units of Discovery of Unknown Bacteria and Function Chinese Academy of Medical SciencesBeijing 100730China

Dear Editor,The emergence of COVID-19 since December 2019 has attracted great attention around the world and reminds the powerful pathogenic potential of viruses(Zhou et al.2020).The subfamily Orthocoronavirinae of the family Coronaviridae contains four genera Alphacoronavirus,Betacoronavirus,Gammacoronavirus,and Deltacoronavirus,which are the largest group of positive-sense,non-segmented,single-stranded,enveloped RNA viruses(Woo et al.2012;Shi et al.2016).The genus Gammacoronavirus currently has five species(https://***/taxonomy/),which are primarily spread through birds(Woo et al.2012).

关键词： taxonomy Corona Jiangxi