检索结果-南通市图书馆

Application of Dual-Energy Computed Tomography for Breast Cancer Diagnosis

International Journal of medical Physics, Clinical Engineering and radiation oncology 2016年第4期5卷 288-297页

作者： Yukiko Okamura Nobuko Yoshizawa Masaru Yamaguchi Ikuo Kashiwakura Department of Radiological Life sciences Hirosaki University Graduate School of Health Sciences Hirosaki Japan Department of Diagnostic Radiology and Nuclear Medicine Hamamatsu University School of Medicine Hamamatsu Japan

The present study aimed to investigate the possibility of using dual-energy computed tomography (CT) before therapy to discriminate between normal breast tissue and tumor tissue in patients with breast cancer, without the need to use a contrast medium. The following patient data were extracted by interview and from the hospital’s radiology information system: height, weight, age, menstrual cycle, CT images of normal tissue and tumors with or without contrast medium, and the histopathological diagnosis of the aspiration biopsy. The median age of the 43 participants was 56 years (range, 30 - 80 years). The CT values were evaluated using a clinical analytical program based on the three-material decomposition technique. Breast cancer was classified into ductal carcinoma in situ, invasive ductal carcinoma, invasive lobular carcinoma, fibromatosis-like metaplastic carcinoma, and apocrine carcinoma. In all conditions, regardless of contrast medium, the CT values of tumor tissues were higher than those of normal breast tissue, indicating the effectiveness of dual-energy CT (DE-CT) in the diagnosis of breast cancer. By contrast, DE-CT showed limited potential for distinguishing ductal carcinoma in situ from invasive ductal carcinoma. There have only been a few reports regarding CT examination of breast cancer, and it is expected this study encourage the development of DE-CT imaging to improve tumor detection in patients with breast cancer.

关键词： Breast Cancer Dual-Energy CT CT Value Contrast Medium Oncological Imaging Ductal Carcinoma in Situ Invasive Ductal Carcinoma

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Treatment options in stage I seminoma

引用

oncology Research 2022年第3期30卷 117-128页

作者： UROS BUMBASIREVIC MARKO ZIVKOVIC MILOS PETROVIC VESNA CORIC NIKOLA LISICIC NEBOJSA BOJANIC Clinic of Urology University Clinical Center of SerbiaBelgrade11000Serbia Faculty of Medicine University of BelgradeBelgrade11000Serbia Institute of medical and Clinical Biochemistry Faculty of MedicineUniversity of BelgradeBelgrade11000Serbia

Seminomas are most commonly diagnosed in clinical stage I(CSI).After orchiectomy,approximately 15%of patients in this stage have subclinical *** radiotherapy(ART)delivered to the retroperitoneum and ipsilateral pelvic lymph nodes has been the mainstay of treatment for many *** highly efﬁcient,with long-term cancer-speciﬁc survival(CSS)rates approaching almost 100%,ART is associated with considerable long-term consequences,particularly cardiovascular toxicity and increased risk of secondary malignancies(SMN).Therefore,active surveillance(AS)and adjuvant chemotherapy(ACT)were developed as alternative treatment *** AS prevents patient overtreatment,it is associated with strict follow-up regimens and increased radiation exposure due to repeated *** to equivalent CSS rates to ART,and lower toxicity,one course of adjuvant carboplatin presents the cornerstone of chemotherapy for CSI *** is almost 100%for patients with CSI seminoma,regardless of the chosen treatment ***,a personalized approach in treatment selection is ***,routine radiotherapy for CSI seminoma patients is no longer ***,it should be reserved for patients who are unﬁt or unwilling for AS or ***ﬁcation of prognostic factors for disease relapse allowed for the development of risk-adapted treatment strategy and stratiﬁcation of patients in low-risk and high-risk *** risk-adapted policy needs further validation,surveillance is currently recommended in low-risk patients,while ACT is reserved for patients with a higher risk of relapse.

关键词： Chemotherapy Radiotherapy Risk-adapted strategy Seminoma Surveillance

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Assessment of Lung Cancer Risk on the Basis of a Biomarker Panel of Circulating Proteins

Assessment of Lung Cancer Risk on the Basis of a Biomarker P...

引用

2019年中国肿瘤标志物学术大会暨第十三届肿瘤标志物青年科学家论坛

作者： sun,nan Florence,Guida Bantis,LeonidasE. Muller,DavidC. Li,Peng Taguchi,Ayumu Dhillon,Dilsher Kundnani,DeepaliL. Patel,NikulJ. Yan,Qingxiang Byrnes,Graham Moons,KarelG.M. Tj?nneland,Anne Panico,Salvatore Claudia ,Agnoli Vineis,Paolo Palli,Domenico Bueno-de-Mesquita,Bas Peeters,PetraH. Agudo,Antonio Huerta,JoseM. Dorronsoro,Miren Barranco,MiguelRodriguez Ardanaz,Eva Travis,RuthC. Byrne,KarlSmith Boeing,Heiner Steffen,Annika Kaaks,Rudolf Hüsing,Anika Trichopoulou,Antonia Lagiou,Pagona LaVecchia,Carlo Severi,Gianluca Boutron-Ruault,Marie-Christine Sandanger,TorkjelM. Weiderpass,Elisabete N?st,ThereseH. Tsilidis,Kostas Riboli,Elio Grankvist,Kjell Johansson,Mikael Goodman,GaryE. Feng,Ziding Brennan,Paul Johansson,Mattias Hanash,Samir M. The University of Texas MD Anderson Cancer Center Genetic Epidemiology Group International Agency for Research on Cancer Department of Biostatistics The University of Texas MD Anderson Cancer Center Department of Epidemiology and Biostatistics Imperial College London School of Public Health Laboratory of Population Health Max Planck Institute for Demographic Research Department of Translational Molecular Pathology The University of Texas MD Anderson Cancer Center Environment and radiation Section International Agency for Research on Cancer Department of Epidemiology Julius Center for Health Sciences and Primary CareUniversity Medical Center Unit of Diet Genesand EnvironmentDanish Cancer Society Research Center Department of Clinical Medicine and Surgery Federico Ⅱ University Epidemiology and Prevention Unit Fondazione IRCCS Istituto Nazionale dei Tumori Molecular and Genetic Epidemiology Unit Human Genetics Foundation Cancer Risk Factors and Life-Style Epidemiology Unit Cancer Research and Prevention Institute-Istituto per lo Studio ela Prevenzione Oncologica Department for Determinants of Chronic Diseases National Institute for Public Health and the Environment Unit of Nutirition and Cancer Cancer Epidemiology Research ProgramCatalan Institute of OncologyBellvitge Institute for Biomedical Research (IDIBELL)L’Hospitalet de Llobregat Department of Epidemiology Murcia Regional Health Council Biomedical Research Institute of Murcia(IMIB-Arrixaca) Centro de Investigación Biomédica en Red Epidemiología y Salud Pública (CIBERESP) Public Health Direction and Biodonostia Research Institute-CIBERESP Escuela Andaluza de Salud Pública Instituto de Investigación Biosanitaria Hospitales Universitarios de Granada/Universidad de Granada Epidemiology Preventionand Promotion Health ServiceNavarra Public Health Institute Instituto de Investigación Sanitaria de Navarra (IdiSNA) Navarra Institute for Health Research Cancer Epidemiology Unit Nuffield Department of Population HealthUniversity of Oxford Department of Epidemi

IMPORTANCE:There is an urgent need to improve lung cancer risk assessment because current screening criteria miss a large proportion of ***:To investigate whether a lung cancer risk prediction model based on a panel of selected circulating protein biomarkers can outperform a traditional risk prediction model and current US screening criteria.

关键词：

来源： cnki会议评论

在线全文

cnki会议

学校读者我要写书评

暂无评论

Feasible Method to Assess the Performance of a Lung Cancer CT Screening CAD System in Clinical Practice: Dependence on Nodule Size and Density

引用

International Journal of medical Physics, Clinical Engineering and radiation oncology 2014年第2期3卷 107-116页

作者： Janaka C. Marasinghe Masaki Ohkubo Hajime Kobayashi Kohei Murao Toru Matsumoto Shusuke Sone Shinichi Wada Fujitsu Ltd. Tokyo Japan Graduate School of Health sciences Niigata University Niigata Japan Graduate School of Health sciences Niigata University Niigata Japan Department of Radiography/Radiotherapy Faculty of Allied Health Sciences University of Peradeniya Peradeniya SriLanka Kensei Clinic Chiba Japan Nagano Health Promotion Corporation Nagano Japan

Detection of small pulmonary nodules is the goal of lung cancer screening. Computer-aided detection (CAD) systems are recommended to use in lung cancer computed tomography (CT) screening to increase the accuracy of nodule detection. Size and density of lung nodules are primary factors in determining the risk of malignancy. Therefore, purpose of this study is to apply computer-simulated virtual nodules based on the point spread function (PSF) measured in same scanner (maintaining spatial resolution condition) to assess the CAD system performance dependence on nodule size and density. Virtual nodules with density differences between lung background and nodule density (ΔCT) values (200, 300 and 400 HU) and different sizes (4 to 8 mm) were generated and fused on clinical images. CAD detection was performed and free-response receiver operating characteristic (FROC) curves were obtained. Results show that both density and size of virtual nodules can affect detection efficiency. Detailed results are possible to use for quantitative analysis of a CAD system performance. This study suggests that PSF-based virtual nodules could be effectively used to assess the lung cancer CT screening CAD system performance dependence on nodule size and density.

关键词： Computed Tomography (CT) Point Spread Function (PSF) Lung Cancer Screening Computer-Aided Detection (CAD) Virtual Nodule

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

脑海绵状血管畸形临床诊疗指南概要：血管瘤联盟科学咨询委员会临床专家组基于系统文献评价的共识推荐

引用

国际脑血管病杂志 2017年第7期25卷 577-591页

作者： Amy Akers Rustam Al-Shahi Salman Issam A. Awad Kristen Dahlem Kelly Flemming Blaine Hart Helen Kim Ignacio Jusue-Torres Douglas Kondziolka Cornelia Lee Leslie Morrison Daniele Rigamonti Tania Rebeiz Elisabeth Toumier-Lasserve Darrel Waggoner Kevin Whitehead 鄂同舟雷宇倪伟顾宇翔 Angioma Alliance Norfolk Virginia Centre for Clinical Brain sciences University of Edinburgh Edinburgh United Kingdom Neurovascular Surgery Program Section of Neurosurgery" University of Chicago Medicine" and Biological Sciences Chicago Illinois Department of Neurology Mayo Clinic Rochester Minnesota Department of Radiology University of New Mexico Albuquerque New Mexico Department of Anesthesia and Perioperative Care Department of Epidemiology and Biostatistics University of California San Francisco San Francisco California Department of Ncurosurgery Johns Hopkins Medicine Baltimore Maryland Departments of Neurosurgery and radiation oncology NYU Langone Medical Center New York City New York Departments of Neurology and Pediatrics University of New Mexico Albuquerque New Mexico Department of Genetics INSERM UMR 1161 Pads France Department of Human Genetics and Pediatrics University of Chicago Medicine and Biological Sciences Chicago Illinois Department of Cardiovascular Medicine University of Utah Salt Lake City Utah 复旦大学附属华山医院神经外科上海200040

背景尽管脑海绵状血管畸形（cerebral cavernous malformation, CCM）的相关研究文献已相当丰富，但在诊断和治疗策略方面仍存在着争议。目的制订CCM诊疗指南。方法作为代表CCM患者和研究的患者支持团体，血管瘤联盟（***）召集了一个包... 详细信息

背景尽管脑海绵状血管畸形（cerebral cavernous malformation, CCM）的相关研究文献已相当丰富，但在诊断和治疗策略方面仍存在着争议。目的制订CCM诊疗指南。方法作为代表CCM患者和研究的患者支持团体，血管瘤联盟（***）召集了一个包括CCM临床专家在内的多学科写作组来帮助总结现有的CCM临床诊疗相关文献，重点关注5个主题：（1）流行病学和自然病程；（2）遗传检测和咨询；（3）诊断标准和影像学标准；（4）神经外科注意事项；（5）神经内科注意事项。写作组根据预定方案进行了文献回顾和证据评价，最终制定推荐意见，并且确立了共识、争议和知识空白。结果根据方法学标准从1983年1月1日至2014年9月31日期间公开发表的1 270篇文献中筛选出98篇，并确定了另外38篇近期或相关的文献。各主题作者利用这些文献总结了现有知识并形成了23项共识诊疗推荐，同时根据美国心脏协会/美国卒中协会标准进行了推荐强度（效应量）和证据水平（确定性估计）评级。其中，尚无A级证据（因为缺乏随机对照试验），B级证据11项（48%），C级证据12项（52%）；Ⅰ级推荐8项（35%），Ⅱ级推荐10项（43%），Ⅲ级推荐5项（22%）。结论现有证据支持对CCM诊疗的推荐，但这些证据的级别和推荐强度普遍较低，因此需要进一步研究来帮助进行更好的临床实践并更新这些推荐。完整的推荐文档包括引用文献的纳入标准、关于各项推荐更详尽的评判标准以及各种争议和知识空白的总结，同样通过了同行评议并可在线获取（***/CCMGuidelines）。

关键词：海绵状血管瘤血管畸形指南推荐

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Pandemic adaptation in oncological management-a tertiary care radiation oncology center experience

引用

Cancer Advances 2022年第4期5卷 1-4页

作者： Dillip Kumar Parida Sandip Kumar Barik Adhar Amritt Minakshi Mishra Poornima Devi Saroj Kumar Das Majumdar Department of Radiotherapy All India Institute of Medical SciencesBhubaneswar 751019India.

The emergence of"Severe Acute Respiratory Syndrome Coronavirus 2(SARS-CoV-2)"caused by the novel coronavirus(COVID-19)had its origin in Wuhan,China,in November-December *** May 27,2021,the pandemic has affected over 220 countries,with 169,094,393 coronavirus cases and 23,512,509 deaths[1].India reported its first case of COVID-19 infection on January 30,2020[2].The rise of COVID-19 cases brought a barrage of many unforeseen problems for cancer patients and health care ***,a robust and systematic policy must be followed for the cancer facility's smooth ***,India has 273,67,935 cases with 3,15,263 deaths as on March 27,2021[3].The second wave in India started from March 2021 and continued till August 2021 with a peak patient peak load of approximately 4 lacks of new cases in early May *** Third wave started in late November 2021 and is still continuing and in weaning *** and Omicron variant were the majority strains during 2nd and 3rd wave respectively.

关键词： continued India deaths

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Quality Control of Dual Energy X-Ray Absorptiometry

引用

International Journal of medical Physics, Clinical Engineering and radiation oncology 2018年第3期7卷 323-329页

作者： M. A. Reza A. K. Paul H. R. Khan M. R. Rahman Physics Discipline Khulna University Khulna Bangladesh Institute of Nuclear Medicine & Allied sciences Khulna Bangladesh

Dual energy X-ray absorptiometry (DXA) is a dominant technique for the measurement of bone mineral density (BMD). Quality control (QC) of DXA is very important for the accuracy of results and correct interpretation made by the physician. We have performed the quality control procedures of Lunar DPX Pro bone densitometer according to the manufacturer’s recommendations and current clinical guidelines at the Institute of Nuclear Medicine & Allied sciences (INMAS), Khulna. The objective of this study is to maximize the performance of the technologist as well as the reliability of the equipment (Linearity, X-ray tube output, Half value layer, Kerma-area product, radiation field size, Fan angle, Spatial resolution, Room safety). The study result shows that the mean BMD reading is 1.004 g/cm2 with a standard deviation of 0.0035 and co-efficient of variation 0.34%. It also shows that the precision of the technologist is good and there is no malfunctioning in the DXA bone densitometer.

关键词： Nuclear Medicine DXA Bone Mineral Density Quality Control Bone Densitometer

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Quality Control of Gamma Camera with SPECT Systems

引用

International Journal of medical Physics, Clinical Engineering and radiation oncology 2017年第3期6卷 225-232页

作者： Md. Razibul Hasan Md. Harunor Rashid Khan Md. Rashedur Rahman Md. Shohel Parvez Md. Rakibul Islam Ashoke Kumar Paul Physics Discipline Khulna University Khulna Bangladesh Institute of Nuclear Medicine & Allied sciences Khulna Bangladesh

Quality control of Gamma Camera with SPECT System is highly valuable for assurance performance characteristic. We report the performance characteristic of gamma camera by intrinsic calibration and verification measurement. The study has been done using the data from Siemens Symbia S Series gamma camera by using a point source 99mTc at the Institute of Nuclear Medicine & Allied sciences (INMAS), Khulna, Bangladesh. From intrinsic calibration and verification flood series, the integral uniformity for the central field of view (CFOV) has been found in between 4.01% and 2.88% and for the useful field of view (UFOV) has been in between 4.77% and 4.30%. The differential uniformity for the CFOV has been in between 1.53% and 2.04% and for the UFOV has been in between 2.32% and 2.77%. According to Operating Instruction Symbia System S Series manual, uniformity can compensate for values exceeding 10%, however while integral uniformity exceed 7%, have to contract Siemens customer service representative. In conclusion, these results show that the intrinsic uniformity of the gamma camera under this condition is within an acceptable range;thus the gamma camera working in INMAS is performed well.

关键词： Gamma Camera SPECT Quality Control Intrinsic Uniformity

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

转录因子FoxM1在恶性肿瘤中的研究进展

引用

中国科学:生命科学 2023年第9期53卷 1239-1246页

作者：李炎宸耿瑞璇赵珂陈野野郑庆飞郑志博中国医学科学院北京协和医学院北京协和医院口腔科北京100730 中国医学科学院北京协和医院国际医疗部北京100730 中国医学科学院北京协和医院胸外科北京100730 Department of radiation oncology College of Medicine and Center for Cancer MetabolismJames Comprehensive Cancer CenterThe Ohio State UniversityColumbus Ohio 43210USA

叉头框转录因子(Forkhead box M1,FoxM1)是转录因子的一种,被认为是多种癌症中肿瘤发展、细胞周期进展、侵袭和转移的主要调节因子,与细胞增殖等过程密切相关.近些年,随着人们对FoxM1的关注,科研人员做出了大量有价值的研究,对FoxM1的... 详细信息

叉头框转录因子(Forkhead box M1,FoxM1)是转录因子的一种,被认为是多种癌症中肿瘤发展、细胞周期进展、侵袭和转移的主要调节因子,与细胞增殖等过程密切相关.近些年,随着人们对FoxM1的关注,科研人员做出了大量有价值的研究,对FoxM1的调控和功能的了解也逐步加深.许多学者以其为靶点,探索关于利用FoxM1的小分子抑制剂作为治疗癌症的新型药物.本文回顾了有关文献,系统阐述了FoxM1的基本结构、功能及在不同肿瘤中的作用,以期为诊断肿瘤性质、评估肿瘤恶性程度、选择新的治疗靶点提供参考.

关键词：转录因子 FoxM1 恶性肿瘤

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

蕈样肉芽肿和Sezary综合征分类和分期的修订方案——国际皮肤淋巴瘤学会和欧洲癌症研究治疗特别工作组的建议（待续）

引用

白血病．淋巴瘤 2008年第6期17卷 466-468页

作者： Elise Olsen Eric Vonderheld Nieola Pimpinelli Rein Willemze Youn Kim Robert Knobler Herschel Zackheim Madeleine Duvic Teresa Estraeh Stanford Lamberg Gary Wood Reinhard Dummer Annamari Ranki Gunter Burg Peter Heald Mark Pittelkow Maria-Grazia Bernengo Wolfram Sterry Liliane Laroche Franz Trautinger Sean Whittaker 张培红(译) 陈辉树(审校) Department of Medicine Divisions of Dermatology and Oncology Duke University Medical Center Durham NC Department of Dermatology Johns Hopkins University Baltimore MD Department of Dermatological sciences University of Florence Florence haly Department of Dermatology Leiden University Medical CenterLeiden The Netherlands Department of Dermatology Stanford University Medical Center Stanford CA Department of Dermatology University of Vienna Vienna Austria Department of Dermatology University of Californiaat San Francisco Department of Dermatology University of Texasat Houston Department of Dermatology University of Barcelona Barcelona Spain Department of Dermatology. University of Wisconsin Madison Department of Dermatology University Hospital Zurich Zurich Switzerland Department of Dermatology and Venereal Diseases Helsinki University Hospital Helsinki Finland Department of Dermatology Yale University New Haven CT Department of Dermatology Mayo CLinic Rochester MN Department of Dermatology University of Turin Turin Italy Department of Dermatology Charit e Humboldt University Berlin Germany Department of fmmuno-Dermatology Hospital Avicenne-University of Paris XIII Paris France St John's Institute of Dermatology Skin Tumour Unit St Thomas' Hospital London United Kingdom 不详

ISCL／EORTC推荐蕈样肉芽肿协作组使用皮肤T细胞淋巴瘤（Cutaneous T-cell lymphoma，CTCL）分类及分期修订方案。这个修订方案吸收了自1979年最初的指南发表以来的有关蕈样肉芽肿（Mycosis Fungoides，MF）和Sezary综合征（Sezary synd... 详细信息

ISCL／EORTC推荐蕈样肉芽肿协作组使用皮肤T细胞淋巴瘤（Cutaneous T-cell lymphoma，CTCL）分类及分期修订方案。这个修订方案吸收了自1979年最初的指南发表以来的有关蕈样肉芽肿（Mycosis Fungoides，MF）和Sezary综合征（Sezary syndrome，SS）肿瘤细胞生物学和诊断技术的进展，明确目前影响研究机构和调查者之间有效交流和（或）MF及SS标准化临床实验发展的某些指标，而且为追踪其他有潜在预后意义的指标提供了一个平台。此外，鉴于皮肤淋巴瘤中非MF／非SS亚型预后和临床特点的差异，本方案是特别针对MF和SS的。除了对本修订方案的评估和分期程序做出推荐外，该文还对修订方案的论据做了讨论。

关键词： Sezary综合征蕈样肉芽肿修订方案皮肤淋巴瘤分类工作组皮肤T细胞淋巴瘤 lymphoma

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：