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Modified magnetic resonance angiography of the liver using sensitivity encoding in comparison with digital subtraction angiography and CT arterial portography

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Hepatobiliary & Pancreatic Diseases International 2005年第2期4卷 185-191页

作者： Masahiko Fujii Hideaki Kawamitsu Kazuro Sugimura First Affiliated Hospital Zhejiang University School of Medicine Hangzhou 310003 China division of ra diology kobe graduate school of medicine Hyogo 6500017 Japan

BACKGROUND: Over 355 patients have received ortho- topic liver transplantation ( OLT) at this hospital since 1993. Preoperative imaging studies of both hepatic vessels and parenchyma in these recipients bettered surgical plan- ning or even precluded the necessity of surgery. Here we report our preliminary results of modified magnetic reso- nance angiography ( Mra ) using sensitivity encoding ( SENSE) through comparative study with conventional digital subtraction angiography (DSA) and CT arterial por- tography (CTAP). METHODS: Sixteen patients with suspected liver diseases were included in the study. All of them received both dy- namic MRI of the liver using SENSE and digital DSA with CTAP within a two-week interval. The four-phase Mra was reconstructed from source images of the coronal dy- namic study. The arterial phase of the modified Mra was compared with DSA in the evaluation of hepatic arteries and the portal phase compared with CT portography recon- structed from source images of CTAP. In dynamic study of the liver, a fixed dose (20 ml) of contrast medium and scan timing were used. RESULTS: The main branches and variations of the hepatic arterial system were well shown on the modified Mra, al- though the marginal branches of hepatic arteries were of poor quality. The figures of portal veins on Mra were as clear as or superior to those of CTAP. In addition, the su- prarenal inferior vena cava (IVC) was well demonstrated on Mra and/or non contrast-enhanced coronal balanced fast-field echo (b-FFE) scan sequence in most cases. MRI detected most parenchymal lesions of the liver and hemo- dynamics of these lesions could be evaluated on source ima- ges of the modified Mra. MRI/Mra also serendipitously revealed several extrahepatic disease entities or variations that were not found on DSA/CTAP. CONCLUSIONS: The modified Mra using SENSE is a cost-effective modality of examination for the demonstra- tion of the whole hepatic vascular system. Combined with MRI, it has t

关键词： orthotopic liver transplantation magnetic resonance imaging magnetic resonance angiography digital subtraction angiography

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Findings of <sup>18</sup>F-Fluorodeoxyglucose Positron-Emission Tomography in Methotrexate-Related Lymphoproliferative Disorder

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Open Journal of radiology 2014年第4期4卷 293-300页

作者： Atsushi K. Kono Kazuhiro Kitajima Hiroshi Mmatsuoka Kyoko Otani Tomoo Itoh Kazuro Sugimura Department of radiology Kobe University Hospital Kobe Japan Department of radiology Kobe University Graduate School of Medicine Kobe Japan division of Medical Oncology/Hematology Department of Medicine Kobe University Graduate School of Medicine Kobe Japan Department of Diagnostic Pathology Kobe University Hospital Kobe Japan

Introduction: The use of methotrexate (MTX) for rheumatoid arthritis (ra) is increasing. However, the immune suppression state leads to the occurrence of lymphoproliferative disorder (MTX-LPD). The purpose of this study was to describe the findings of 18F-fluorodeoxyglucose (FDG) positron emission tomography (PET) in MTX-LPD patients, and compare it with non-MTX-related malignant lymphoma (ML). Materials and Methods: We retrospectively reviewed 11 MTX-LPD patients (9 female, mean age 68.3 years) and 21 ML patients (7 female, mean age 60.6 years) with a histopathological diagnosis. FDG-PET imaging was performed using a standard oncology procedure. We assessed the disease distribution based on FDG-PET images and measured the maximum standardized up take values (SUVmax) for each region. Results: Mean values of SUVmax in MTX-LPD and ML were 14.6 and 17.2, respectively (p = 0.49). In MTX-LPD, 55 lesions met the Cotswold classification, consisting of 37 nodal and 18 extranodal lesions. In ML, 82 lesions were found, consisting of 68 nodal and 14 extranodal lesions. MTX-LPD showed a higher incident of the involvement in extranodal lesions throughout the whole body (p < 0.001). Conclusion: Because this disease occurs widely throughout the whole body, we need to pay attention to the less frequent sites as well when performing PET imaging in patients with MTX-LPD.

关键词： Fluorodeoxyglucose (FDG) F 18 Lymphoma Methotrexate Positron-Emission Tomography (PET) Rheumatoid Arthritis

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