检索结果-南通市图书馆

Comprehensive study of protein phosphorylation， acetylation， ubiquitination and S-nitrosylation profiles in pre- and post-rigor meat

在线全文

学校读者我要写书评

暂无评论

food science and Human Wellness 2024年

作者： Chi Ren Yuqiang Bai Yejun Zhang Chengli Hou Li Chen James D.Morton Xin Li Zhenyu Wang Dequan Zhang Institute of food science and technology， Chinese Academy of Agricultural sciences/Key Laboratory of Agro-products Quality & Safety in harvest， Storage， Transportation， Management and Control， Ministry of Agriculture and Rural Affairs Faculty of Agriculture and Life sciences， Lincoln University Lincoln 7647， New Zealand

This study investigated the integrated atlas of protein phosphorylation， acetylation， ubiquitination and S-nitrosylation in pre-rigor (0.5 h) and post-rigor (5 d) lamb to interpret the roles of protein post-translational modifications (PTMs) during meat aging. The results showed that the most common PTMs in postmortem meat were phosphorylated proteins. PTMs regulation during the postmortem period altered proteins involved in metabolic pathways and muscle contraction. The phosphorylation and ubiquitination of proteins located in mitochondria and nuclear changed significantly between 0.5 h and 5 d postmortem. Gene set enrichment analysis (GSEA) revealed possible roles of total PTMs proteins， with a general downregulation of phosphorylation， acetylation and ubiquitination. There was a weak correlation in the lysine PTM of acetylation and ubiquitination at the same site in postmortem meat. Multiple PTMs of proteins in glycolysis， TCA cycle， muscle contraction and the calcium signaling pathway cooperatively regulate meat quality development from pre-rigor to post-rigor.

关键词：

Weight gain after 35 years of age is associated with increased breast cancer risk: findings from a large prospective cohort study

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Cancer Biology & Medicine 2024年第8期21卷 651-655页

作者： Katherine De la Torre Woo-Kyoung Shin Hwi-Won Lee Dan Huang Sukhong Min Aesun Shin Wonshik Han Daehee Kang Department of Preventive Medicine Seoul National University College of Medicine Department of Biomedical sciences Seoul National University Graduate School division of food and Pharmaceutical technology Mokwon University Integrated Major in Innovative Medical science Seoul National University Graduate School Cancer Research Institute Seoul National University Department of Surgery Seoul National University College of Medicine Biomedical Research Institute Seoul National University Hospital

Adiposity affects lifetime estrogen exposure, which is a key factor in breast carcinogenesis. However, adiposity effects,often assessed as the body mass index （BMI）, on pre-and post-menopausal breast cancer risk are paradoxical. Body weight gain may reflect body fat mass accumulation during adulthood better than the BMI, potentially representing age-related metabolic changes1.

关键词： ADULTHOOD

Soaking Induced Changes in Chemical Composition, Glycemic Index and Starch Characteristics of Basmati Rice

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Rice science 2015年第5期22卷 227-236页

作者： S.J.KALE S.K.JHA G.K.JHA J.P.SINHA S.B.LAL division of food science and post harvest technology Indian Agricultural Research Institute division of Agricultural Economics Indian Agricultural Research Institute division of Agricultural Engineering Indian Agricultural Research Institute division of Computer Applications Indian Agricultural Research Institute

An attempt was made to determine the qualitative changes in basmati rice （Pusa Basmati 1121, PBl121） during soaking at 40 ℃ to 80 ℃. Soaking temperature had significant effect （a = 0.01） on chemical composition, glycemic index and starch characteristics of rice. Starch content, apparent amylose content, crude protein content and crude fat content in un-soaked rice were found to be 73.24%, 27.26%, 8.79% and 2.56%, respectively, but differences in these traits were observed after soaking. Amylose to amylopectin ratio （Am/Ap） decreased from 0.59 to 0.52 （soaked at 80 ℃）. Crude fibre and crude ash contents increased after soaking. The mineral composition （K, P, S, Ca, Mg, Mn, Fe, Cu and Zn） in soaked rice was found to be 16.46% higher than un-soaked rice at the same degree of polishing. Glycemic index of un-soaked rice was found to be 58.41, but decreased to 54.31 after soaking at 80 ℃. Pasting properties, scanning electron microscope images, and X-ray diffractograms suggested partial gelatinization of starch in the temperature range of 60 ℃ to 80 ℃. Based on qualitative changes in rice （apparent amylose content, Am/Ap ratio and crystallinity rate）, it was concluded that intermediate soakincl temperatures （60 ℃ to 70 ℃） would be useful for soaking of PB1121.

关键词： basmati rice soaking glycemic index starch characteristic temperature chemicalcomposition crystallinity

Pericarp and seed of litchi and longan fruits:constituent, extraction, bioactive activity, and potential utilization

在线全文

学校读者我要写书评

暂无评论

Journal of Zhejiang University-science B(Biomedicine & Biotechnology) 2019年第6期20卷 503-512页

作者： Xiang-rong ZHU Hui WANG Jian SUN Bao YANG Xue-wu DUAN Yue-ming JIANG Key Laboratory of Plant Resource Conservation and Sustainable Utilization Key Laboratory of Post-Harvest Handling of FruitsMinistry of AgricultureSouth China Botanical GardenChinese Academy of Sciences Institute of post-harvest technology of Agricultural Products College of Food ScienceFujian Agriculture and Forestry University Agro-food science and technology Research Institute Guangxi Academy of Agricultural Sciences

Litchi(Litchi chinensis Sonn.)and longan(Dimocarpus longan Lour.)fruits have a succulent and white aril with a brown seed and are becoming popular *** two fruits have been used in traditional Chinese medicine as popular herbs in the treatment of neural pain,swelling,and cardiovascular *** pericarp and seed portions as the by-products of litchi and longan fruits are estimated to be approximately 30%of the dry weight of the whole fruit and are rich in bioactive *** the recent years,many biological activities,such as tyrosinase inhibitory,antioxidant,anti-inflammatory,immunomodulatory,anti-glycated,and anti-cancer activities,as well as memory-increasing effects,have been reported for the litchi and longan pericarp and seed extracts,indicating a potentially significant contribution to human *** the increasing production of litchi and longan fruits,enhanced utilization of the two fruit by-products for their inherent bioactive constituents in relation to pharmacological effects is urgently *** paper reviews the current advances in the extraction,processing,identification,and biological and pharmacological activities of constituents from litchi and longan *** utilization of litchi and longan pericarps and seeds in relation to further research is also discussed.

关键词： Bioactive compound Extraction Litchi Longan Pharmacological activity Utilization

Recent advances in chemical protein synthesis:method developments and biological applications

在线全文

学校读者我要写书评

暂无评论

science China Chemistry 2024年第4期67卷 1060-1096页

作者： Suwei Dong Ji-Shen Zheng Yiming Li Huan Wang Gong Chen Yongxiang Chen Gemin Fang Jun Guo Chunmao He Honggang Hu Xuechen Li Yanmei Li Zigang Li Man Pan Shan Tang Changlin Tian Ping Wang Bian Wu Chuanliu Wu Junfeng Zhao Lei Liu State Key Laboratory of Natural and Biomimetic Drugs and School of Pharmaceutical SciencesPeking UniversityBeijing 100191China division of Life sciences and Medicine University of Science and Technology of ChinaHefei 230027China School of food and Biological Engineering Engineering Research Center of Bio-processMinistry of EducationHefei University of TechnologyHefei 230009China School of Chemistry and Chemical Engineering Nanjing UniversityNanjing 210023China State Key Laboratory of Elemento-Organic Chemistry Nankai UniversityTianjin 300071China Department of Chemistry Tsinghua UniversityBeijing 100084China Institute of Health sciences Anhui UniversityHefei 230601China College of Chemistry Central China Normal UniversityWuhan 430079China School of Chemistry and Chemical Engineering South China University of TechnologyGuangzhou 510640China School of Medicine or Institute of Translational Medicine Shanghai UniversityShanghai 200444China Department of Chemistry The University of Hong KongHong Kong 999077China Shenzhen Graduate School Peking UniversityShenzhen 518055China School of Chemistry and Chemical Engineering Shanghai Jiao Tong UniversityShanghai 200240China School of Life sciences University of Science and Technology of ChinaHefei 230026China Department of Chemical Biology Shanghai Jiao Tong UniversityShanghai 200240China Institute of Microbiology Chinese Academy of SciencesBeijing 100101China Department of Chemistry Xiamen UniversityXiamen 361005China School of Pharmaceutical science Guangzhou Medical UniversityGuangzhou 511436China

The central dogma of modern biology underscores the pivotal roles proteins play in diverse biological processes,the study of which necessitates advanced methods to produce proteins with precision and *** protein synthesis,a powerful approach utilizing chemical reactions for the de novo construction of structurally accurate proteins,has emerged as a transformative tool for studying proteins and generating protein derivatives/mimics inaccessible by natural biological machinery,including post-translationally modified proteins,proteins comprised of unnatural amino acids,as well as mirror-image *** review summarizes recent strides in synthetic method developments for chemical protein synthesis,including innovative techniques in solid-phase peptide synthesis,the challenges presented by difficult sequences in either synthesis or folding and the exploration of novel ligation reactions using both chemical and enzymatic ***,the review also delves into newly developed protocols for site-selective protein modifications and the generation of stapled or macrocyclized peptides/miniproteins,highlighting the power of chemical methods to make structurally diverse *** applications of synthetic proteins in investigating post-translational modifications(phosphorylation,lipidation,glycosylation,ubiquitination,etc.),mirror-image biological processes and drug development are further ***,these topics provide a comprehensive overview of the current landscape of chemical protein synthesis.

关键词： chemical protein synthesis solid-phase peptide synthesis ligation reactions post-translational modifications mirror-image proteins peptide drugs

Cellulosomal hemicellulases:Indispensable players for ensuring effective lignocellulose bioconversion

在线全文

学校读者我要写书评

暂无评论

Green Carbon 2024年第1期2卷 57-69页

作者： Min Xiao Ya-Jun Liu Edward A.Bayer Akihiko Kosugi Qiu Cui Yingang Feng CAS Key Laboratory of Biofuels Qingdao Institute of Bioenergy and Bioprocess TechnologyChinese Academy of SciencesQingdao 266101China Shandong Provincial Key Laboratory of Synthetic Biology Qingdao Institute of Bioenergy and Bioprocess TechnologyChinese Academy of SciencesQingdao 266101China Shandong Engineering Laboratory of Single Cell Oil Qingdao Institute of Bioenergy and Bioprocess TechnologyChinese Academy of SciencesQingdao 266101China Shandong Energy Institute Qingdao 266101China Qingdao New Energy Shandong Laboratory Qingdao 266101China University of Chinese Academy of sciences Beijing 100049China Department of Biomolecular sciences The Weizmann Institute of ScienceRehovot 7610001Israel Department of Life sciences and the National Institute for Biotechnology in the Negev Ben-Gurion University of the NegevBeer-Sheva 8499000Israel Biological Resources and post-harvest division Japan International Research Center for Agricultural Sciences(JIRCAS)1-1 OhwashiTsukubaIbaraki 305-8686Japan

The bioconversion of lignocellulose has attracted global attention,due to the significant potential of agricultural and forestry wastes as renewable zero-carbon resources and the urgent need for substituting fossil *** cellulosome system is a multi-enzyme complex produced by anaerobic bacteria,which comprises cellulases,hemicellulases,and associated enzymatic and non-enzymatic components that promote biomass *** enhance their efficiency in degrading recalcitrant lignocellulosic matrices,cellulosomes have been employed to construct biocatalysts for lignocellulose bioconversion,such as consolidated bioprocessing and consolidated ***,the second most abundant polysaccharides in plant cell walls,hold valuable application potential but can also induce inhibitory effects on cellulose hydrolysis,thus highlighting the indispensable roles of hemicellulases within the cellulosome *** review evaluated current research on cellulosomal hemicellulases,comparing their types,abundance,and regulation,primarily focusing on eight known cellulosome-producing species of different *** also reviewed their growth conditions,their hemicellulose-degrading capabilities,and the inhibitory effects of hemicellulose on cellulosome-based lignocellulose ***,we proposed strategies for targeted enhancement of hemicellulase in cellulosomes to improve lignocellulose bioconversion in future studies.

关键词： Cellulosome Lignocellulose Hemicellulase Saccharification Biocatalyst

Recent advances in extraction of antioxidants from plant by-products processing industries

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

food Quality and Safety 2017年第1期1卷 61-81页

作者： M.Selvamuthukumaran John Shi Department of food science and post harvest technology Institute of TechnologyHaramaya UniversityPO Box 138Dire DawaEthiopia Guelph Research and Development Center Agriculture and Agri-Food Canada93 Stone Road WestGuelphOntario N1G 5C9Canada

The by-products obtained from plant processing industries are the cheap source of bioactive compounds especially *** of bioactive compounds can be obtained by using conventional and non-conventional *** efficiency of any conventional method mainly depends on the choice of *** major challenges of conventional extraction are longer extraction time,requirement of costly and high purity solvent,evaporation of the huge amount of solvent,low extraction selectivity,and thermal decomposition of thermolabile *** overcome these limitations of conventional extraction methods,new and promising extraction techniques are *** techniques are referred as non-conventional extraction ***,in this review,some of the most promising techniques such as ultrasoundassisted extraction,pulsed electric field extraction,enzyme-assisted extraction,microwave-assisted extraction,pressurized liquid extraction,supercritical fluid extraction,pressurized low-polarity water extraction,and molecular distillation were *** process systems along with industrial applications for non-conventional method of antioxidants extraction were discussed,and the comparative efficacies of different extraction methods were *** conventional technologies by non-conventional ones for the extraction of valuable compounds from plant by-products processing industries has several advantages,which includes reduction of the processing time,energy consumption,and the uses of harmful and expensive solvents and increase in the extraction *** and development of hybrid methods should be investigated,while considering plant material characteristics and choice of compounds in *** choice of standard methods also influences the measurement of extraction *** increasing economic significance of bioactive compounds and commodities rich in these bioactive compounds may lead to find out more sophi

关键词： Antioxidants Extraction Non-conventional methods Plant by-products Pulsed electric field extraction Ultrasoundassisted extraction

Ellagic acid in strawberry(Fragaria spp.):Biological,technological,stability,and human health aspects

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

food Quality and Safety 2017年第4期1卷 227-252页

作者： Selva Muthukumaran Carole Tranchant John Shi Xingqian Ye Sophia Jun Xue Department of food science and post-harvest technology Institute of TechnologyHaramaya UniversityPost Box 138Dire DawaEthiopia School of food science Nutrition and Family StudiesFaculty of Health Sciences and Community ServicesUniversitéde MonctonMonctonNew Brunswick E1A 3E9Canada***Guelph Research and Development CenterAgriculture and Agri-Food Canada93 Stone Road WestGuelphOntario N1G 5C9Canada School of Biosystems Engineering and food science Zhejiang UniversityHangzhouChina

Ellagic acid(EA)is one of the plant phenolics associated with human health *** derives from ellagitannins found in some nuts,seeds,and fruits,especially *** are considered a functional food and nutraceutical source,mainly because of their high concentration of EA and its *** review presents the current state of knowledge regarding EA,focusing on its content in strawberry plants,stability during processing and storage of strawberry-based foods,production methods,and relevance to human *** alternatives to acid-solvent extraction,fermentation-enzymatic bioprocesses hold great promises for more eco-efficient production of EA from plant *** fruits are generally rich in EA,with large variations depending on cultivar,growth conditions and maturity at *** EA contents are also reported in strawberry achenes and leaves,and in wild *** postharvest storage,processing and subsequent storage can influence EA *** low concentration in strawberry juice and wine can be increased by incorporating pre-treated *** recognition of strawberries as functional foods is substantiated by evidence of EA biological effects,including antioxidant,antiinflammatory,antidiabetic,cardioprotective,neuroprotective,and prebiotic *** health benefits attributed to EA-rich foods are thought to involve various protective mechanisms at the cellular *** EA is converted by the intestinal microbiota to urolithins,which are better absorbed than EA and may contribute significantly to the health effects attributed to EA-rich *** on the evidence available,strawberry EA shows strong promises for functional,nutraceutical,and pharmaceutical *** research should be directed at quantifying EA in different parts of the strawberry plant and in their byproducts;optimizing EA production from byproducts;understanding the biological actions of EA-derived metabolites in vivo,inc

关键词： Strawberry plant Ellagic acid Processing Metabolism Bioacti

Antimicrobial Activity of Acidified Sodium Chlorite and Cell Free Culture Supernatent of Lactic Acid Bacteria against <i>Salmonella</i>Typhimurium

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Biosciences and Medicines 2015年第11期3卷 128-135页

作者： Sangeeta Singh Ajit Singh Yadav Priyanka Bharti Applied science Department Indian Institute of Information Technology Allahabad India food Microbiology Lab Post Harvest Technology Division Central Avian Research Institute Bareilly India

Most methods used by food industries to decontaminate eggs involve washing of egg surface with various chemicals. In this study, the effectiveness of two organic decontaminants viz., acidified sodium chlorite (ASC) and cell free culture supernatant (CFCS) of two lactic acid bacteria (Lactobacillus plantarum and Pediococcus cerevisiae) was evaluated for the decontamination of spiked Salmonella Typhimurium on chicken egg shell surface. Acidified sodium chlorite at 100 μl/L concentration with the contact time of 20 min completely inhibited S. Typhimurium on egg shell surface while at 50 μl/L concentration 1 - 2 log10 units reduction was observed in counts of S. Typhimurium as compared to control group. Likewise, CFCS of P. cerevisiae completely inhibited the growth of S. Typhimurium on 30 min contact, whereas L. plantarum and combination of both were revealed significant reduction in the counts of S. Typhimurium counts.

关键词： Acidified Sodium Chlorite Eggs Lactobacillus plantarum and Pediococcus cerevisiae and Salmonella Typhimurium