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Biodesign Research to Advance the Principles and Applications of Biosystems Design

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BioDesign Research 2019年第1期2019卷 1-4页

作者： Xiaohan Yang Lei S.Qi Alfonso Jaramillo Zong-Ming(Max)Cheng Biosciences division Oak Ridge National LaboratoryOak RidgeTN 37831USA The Center for Bioenergy Innovation Oak Ridge National LaboratoryOak RidgeTN 37831USA Department of bioengineering Stanford UniversityStanfordCA 94305USA Department of Chemical and Systems Biology Stanford UniversityStanfordCA 94305USA Stanford ChEM-H Stanford UniversityStanfordCA 94305USA Warwick Integrative Synthetic Biology Centre(WISB)and School of Life Sciences University of WarwickCV47AL CoventryUK ISSB CNRSUniv EvryCEAUniversitéParis-Saclay91025 EvryFrance Institute for Integrative Systems Biology(I2SysBio) University of Valencia-CSIC46980 PaternaSpain Department of Plant Sciences University of TennesseeKnoxvilleTN 37996USA Nanjing Agricultural University NanjingJiangsu ProvinceChina

Over the course of civilization,humans have increasingly expanded their freedom to live a better *** comparison with the primitive society,our modern society has many more choices of life-supporting resources,such as yearround food supply,permanent shelters,diverse energy sources,and effective preventive and curing ***,our society is currently still heavily relying on the resources provided by Mother Nature,which cannot meet the future global needs in terms of both quantity and quality under the pressure of population growth,natural resource reduction,and environmental *** example,the food sources originating from plants,animals,or microbes do not have the nutrition balance for optimal human health[1–3].Climate change and environmental deterioration threaten the food security[4–6].Increasingly,infectious diseases(e.g.,HIV/AIDS),genetic diseases(e.g.,cancer),and improper lifestyle-related disorders(e.g.,obesity)become more prevalent and remain challenging to be prevented,controlled,and *** medical technologies and modern medicine development are also meeting the ceiling.

关键词： expanded supporting deterioration

Wastewater sequencing reveals early cryptic SARS-CoV-2 variant transmission

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四川生理科学杂志 2022年第6期44卷 1118-1118页

作者： Smruthi Karthikeyan Department of Pediatrics University of California San Diego La Jolla CA USA Department of Biomedical Informatics University of California San Diego La Jolla California USA Department of Computer Science and Engineering University of California San Diego La Jolla CA USA Department of bioengineering University of California San Diego La Jolla CA USA Department of Immunology and Microbiology The Scripps Research Institute La Jolla CA USA Expedited COVID Identification Environment (EXCITE) Laboratory Department of Pediatrics University of California San Diego La Jolla CA USA Department of Obstetrics Gynecology and Reproductive Sciences University of California San Diego La Jolla CA USA COVID-19 Detection Investigation Surveillance Clinical and Outbreak Response California Department of Public Health Richmond CA USA Sanford Consortium of Regenerative Medicine University of California San Diego La Jolla CA USA Department of Cellular and Molecular Medicine University of California San Diego La Jolla CA USA Student Health and Well-Being University of California San Diego La Jolla CA USA Center for Computational Biology and Bioinformatics University of California San Diego La Jolla CA USA Institute for Genomic Medicine University of California San Diego La Jolla CA USA Operational Strategic Initiatives University of California San Diego La Jolla CA USA Return to Learn University of California San Diego La Jolla CA USA Student Affairs University of California San Diego La Jolla CA USA Academic Affairs University of California San Diego La Jolla CA USA Department of Pathology University of California San Diego La Jolla CA USA Scripps Health San Diego La Jolla CA USA Rady Children’s Institute for Genomic Medicine San Diego CA USA Sharp Healthcare San Diego CA USA Helix San Mateo CA USA County of San Diego Health and Human Services Agency San Diego CA USA Herbert Wertheim School of Public Health and Human Longevity Science Univers

As SARS-CoV-2 continues to spread and evolve,detecting emerging variants early is critical for public health *** lineage prevalence by clinical testing is infeasible at scale,especially in areas with limited resources,participation,or testing/sequencing capacity,which can also introduce ***-CoV-2 RNA concentration in wastewater successfully tracks regional infection dynamics and provides less biased abundance estimates than clinical testing4,*** virus genomic sequences in wastewater would improve community prevalence estimates and detect emerging variants.

关键词： wastewater Wastewater testing

Fungal diversity notes 1036-1150:taxonomic and phylogenetic contributions on genera and species of fungal taxa

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Fungal Diversity 2019年第3期96卷 1-242页

作者： Kevin D.Hyde Danushka S.Tennakoon Rajesh Jeewon DJayarama Bhat Sajeewa S.N.Maharachchikumbura Walter Rossi Marco Leonardi Hyang Burm Lee Hye Yeon Mun Jos Houbraken Thuong T.T.Nguyen Sun Jeong Jeon Jens Christian Frisvad Dhanushka N.Wanasinghe Robert Lucking Andre Aptroot Marcela E.S.Caceres Samantha C.Karunarathna Sinang Hongsanan Rungtiwa Phookamsak Nimali Ide Silva Kasun M.Thambugala Ruvishika S.Jayawardena Indunil C.Senanayake Saranyaphat Boonmee Jie Chen Zong-Long Luo Chayanard Phukhamsakda Olinto L.Pereira Vanessa P.Abreu Andre Wilson Campos Rosado Buyck Bart Emile Randrianjohany Vale rie Hofstetter Tatiana B.Gibertoni Adriene Mayrada Silva Soares Helio Longoni Plautz Jr Helen Maria Pontes Sotao William Kalhy Silva Xavier Jadson Diogo Pereira Bezerra Thays Gabrielle Linsde Oliveira Cristina Mariade Souza-Motta Oliane Maria Correia Magalhaes Digvijayini Bundhun Dulanjalee Harishchandra Ishara S.Manawasinghe Wei Dong Sheng-Nan Zhang Dan-Feng Bao Milan C.Samarakoon Dhandevi Pem Anuruddha Karunarathna Chuan-Gen Lin Jing Yang Rekhani H.Perera Vinit Kumar Shi-Ke Huang Monika C.Dayarathne Anusha H.Ekanayaka Subashini C.Jayasiri Yuanpin Xiao Sirinapa Konta Tuula Niskanen Kare Liimatainen Yu-Cheng Dai Xiao-Hong Ji Xue-Mei Tian Armin Mesic Sanjay K.Singh Kunthida Phutthacharoen Lei Cai Touny Sorvongxay Vinodhini Thiyagaraja Chada Norphanphoun Napalai Chaiwan Yong-Zhong Lu Hong-Bo Jiang Jin-Feng Zhang Pranami D.Abeywickrama Janith V.S.Aluthmuhandiram Rashika S.Brahmanage Ming Zeng Thilini Chethana Deping Wei Martina Reblova Jacques Fournier Jana Nekvindova Renan do Nascimento Barbosa Jose Ewerton Felintodos Santos Neiva Tintide Oliveira Guo-Jie Li Damien Ertz Qiu-Ju Shang Alan J.L.Phillips Chang-Hsin Kuo Erio Camporesi Timur S.Bulgakov Saisamorn Lumyong E.B.Gareth Jones Putarak Chomnunti Eleni Gentekaki Frank Bungartz Xiang-Yu Zeng Sally Fryar Zdenko Tkalcec Junmin Liang Guangshuo Li Ting-Chi Wen Paras Nath Singh Yusufjon Gafforov Itthayakorn Promputtha Erandi Yasanthika Ishani D.Goonasekara Rui-Lin Zhao Qi Zhao Paul M Key Laboratory for Plant Diversity and Biogeography of East Asia Kunming Institute of BotanyChinese Academy of ScienceKunming 650201YunnanPeople’s Republic of China School of Science Mae Fah Luang UniversityChiang Rai 57100Thailand Center of Excellence in Fungal Research Mae Fah Luang UniversityChiang Rai 57100Thailand East and Central Asia Regional Office World Agroforestry Centre(ICRAF)Kunming 650201YunnanPeople’s Republic of China Department of Biology Faculty of ScienceChiang Mai UniversityChiang Mai 50200Thailand Mushroom Research Foundation 128 M.3 Ban Pa Deng T.Pa PaeA.Mae TaengChiang Mai 50150Thailand Department of Plant Medicine National Chiayi University300 Syuefu RoadChiayi City 60004TaiwanPeople’s Republic of China Department of Health Sciences Faculty of ScienceUniversity of MauritiusReduitMauritius Formerly Department of Botany Goa UniversityGoaIndia No.128/1-J Azad Housing SocietyCurcaGoa Velha 403108India Department of Crop Sciences College of Agricultural and Marine SciencesSultan Qaboos UniversityPO Box 8123 Al KhoudOman Sect.Environmental Sciences Dept.MeSVAUniversity of L’Aquila67100 CoppitoAQItaly division of Food Technology Biotechnology&AgrochemistryCollege of Agriculture&Life SciencesChonnam National UniversityGwangju 61186Korea Fungal Resources Research division NNIBRSangju-si 37242Korea Westerdijk Fungal Biodiversity Institute Uppsalalaan 83584 CT UtrechtThe Netherlands Department of Biotechnology and Biomedicine DTUBioengineeringTechnical University of Denmark2800 Kongens LyngbyDenmark Botanischer Garten und Botanisches Museum Berlin Freie Universitat BerlinKonigin-Luise-StraßBe 6-814195 BerlinGermany Laboratorio de Botanica/Liquenologia Instituto de BiocienciasUniversidade Federal de Mato Grosso do SulAvenida Costa e Silva s/nBairro UniversitarioCampo GrandeMatto Grosso do Sul CEP 79070-900Brazil Departamento de Biociencias Universidade Federal de SergipeItabaianaSergipe CEP:49500-000Brazil Shenzhen Key Laboratory of Microbial

This article is the tenth series of the Fungal Diversity Notes,where 114 taxa distributed in three phyla,ten classes,30 orders and 53 families are described and *** described in the present study include one new family(*** in Dothideomycetes),five new genera(Caatingomyces,Cryptoschizotrema,Neoacladium,Paramassaria and Trochilispora)and 71 new species,(*** thailandica,Amniculicola aquatica,***,Angustimassarina sylvatica,Blackwellomyces lateris,Boubovia gelatinosa,Buellia viridula,Caatingomyces brasiliensis,Calophoma humuli,Camarosporidiella mori,Canalisporium dehongense,Cantharellus brunneopallidus,***,Castanediella meliponae,Coprinopsis psammophila,Cordyceps succavus,Cortinarius minusculus,***,Diaporthe italiana,***,Diatrypella delonicis,Dictyocheirospora aquadulcis,***,Digitodesmium chiangmaiense,Distoseptispora dehongensis,***,Dothiorella styphnolobii,Ellisembia aurea,Falciformispora aquatic,Fomitiporia carpinea,***,Grammothele aurantiaca,***,Hermatomyces bauhiniae,Jahnula queenslandica,Kamalomyces mangrovei,Lecidella yunnanensis,Micarea squamulosa,Muriphaeosphaeria angustifoliae,Neoacladium indicum,Neodidymelliopsis sambuci,Neosetophoma miscanthi,***,Nodulosphaeria aquilegiae,***,Paramassaria samaneae,Penicillium circulare,***,***-pumilae,***,***,Phaeoisaria siamensis,Phaeopoacea asparagicola,Phaeosphaeria penniseti,Plectocarpon galapagoense,Porina sorediata,Pseudoberkleasmium chiangmaiense,Pyrenochaetopsis sinensis,Rhizophydium koreanum,Russula prasina,Sporoschisma chiangraiense,Stigmatomyces chamaemyiae,***,***,***,***,Thysanorea uniseptata,Torula breviconidiophora,***,Trochilispora schefflerae and Vaginatispora palmae).Further,twelve new combinations(*** cryptotrema,Prolixandromyces australi,***,***,***,P.

关键词： 71 new taxa Ascomycota Basidiomycota Dothideomycetes Eurotiomycetes Lecanoromycetes Leotiomycetes Pezizomycetes Phylogeny Taxonomy

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地肤子抑菌活性成分筛选

化学与生物工程 2019年第2期36卷 28-31页

作者：闫梦茹张文博罗国平 Demetra Simion 王小宁陈程西安医学院药学院陕西西安710021 陕西科技大学陕西省轻化工助剂化学与技术协同创新中心陕西西安710021 陕西农产品加工技术研究院陕西西安710021 The Research Development National Institute for Textiles and Leather Division Leather and Footwear Research Institute

以最小抑菌浓度为指标,采用二倍稀释法分别测试地肤子乙醇提取物中的石油醚相、乙酸乙酯相、正丁醇相和水相萃取物对4株细菌和5株植物病原菌的抑制作用;再对抑菌活性较强的萃取物进行分离纯化,通过二倍稀释法测试所分离化合物的抑菌活性... 详细信息

以最小抑菌浓度为指标,采用二倍稀释法分别测试地肤子乙醇提取物中的石油醚相、乙酸乙酯相、正丁醇相和水相萃取物对4株细菌和5株植物病原菌的抑制作用;再对抑菌活性较强的萃取物进行分离纯化,通过二倍稀释法测试所分离化合物的抑菌活性,并对其结构进行表征。结果表明,正丁醇相萃取物的抑菌活性最强,从中分离得到3个化合物,其中化合物Ⅰ的抑菌活性较强,对大肠杆菌具有显著的抑制作用,其最小抑菌浓度为31.3μg·mL-1,经1 HNMR、IR及高分辨质谱等鉴定化合物Ⅰ为齐墩果酸。齐墩果酸有较强的抑菌活性,是地肤子抑菌活性的物质基础。

关键词：地肤子抑菌活性化学成分结构鉴定

Diel dynamics of multi-omics in elkhorn fern provide new insights into weak CAM photosynthesis

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Plant Communications 2023年第5期4卷 208-222页

作者： Cheng Li Wenjie Huang Xiaoxu Han Guohua Zhao Wenyang Zhang Weijun He Bao Nie Xufeng Chen Taijie Zhang Wenhui Bai Xiaopeng Zhang Jingjing He Cheng Zhao Alisdair RFernie Timothy JTschaplinski Xiaohan Yang Shijuan Yan Li Wang Shenzhen Branch Guangdong Laboratory for Lingnan Modern AgricultureGenome Analysis Laboratory of the Ministry of AgricultureAgricultural Genomics Institute at ShenzhenChinese Academy of Agricultural SciencesShenzhenChina Guangdong Key Laboratory for Crop Germplasm Resources Preservation and Utilization Agro-biological Gene Research CenterGuangdong Academy of Agricultural SciencesGuangzhouChina Biosciences division Oak Ridge National LaboratoryOak RidgeTN 37831USA The Center for Bioenergy Innovation Oak Ridge National LaboratoryOak RidgeTN 37831USA Max Planck Institute of Molecular Plant Physiology Am Muhlenberg 114476 Potsdam-GolmGermany Key Laboratory of Southern Subtropical Plant Diversity Fairy Lake Botanical GardenShenzhen&Chinese Academy of ScienceShenzhenChina Institute of Plant Protection Guangdong Academy of Agricultural SciencesKey Laboratory of Green Prevention and Control on Fruits and Vegetables in South ChinaMinistry of Agriculture and Rural AffairsGuangdong Provincial Key Laboratory of High Technology for Plant ProtectionGuangzhouChina Kunpeng Institute of Modern Agriculture at Foshan Chinese Academy of Agricultural SciencesFoshanChina

Crassulacean acid metabolism(CAM)has high water-use efficiency(WUE)and is widely recognized to have evolved from C3 *** plant lineages have convergently evolved CAM,but the molecular mechanism that underlies C3-to-CAM evolution remains to be *** bifurcatum(elkhorn fern)provides an opportunity to study the molecular changes underlying the transition from C3 to CAM photosynthesis because both modes of photosynthesis occur in this species,with sporotrophophyll leaves(SLs)and cover leaves(CLs)performing C3 and weak CAM photosynthesis,***,we report that the physiological and biochemical attributes of CAM in weak CAM-performing CLs differed from those in strong CAM *** investigated the diel dynamics of the metabolome,proteome,and transcriptome in these dimorphic leaves within the same genetic background and under identical environmental *** found that multi-omic diel dynamics in *** exhibit both tissue and diel *** analysis revealed temporal rewiring of biochemistry relevant to the energy-producing pathway(TCA cycle),CAM pathway,and stomatal movement in CLs compared with *** also confirmed that PHOSPHOENOLPYRUVATE CARBOXYLASE KINASE(PPCK)exhibits convergence in gene expression among highly divergent CAM *** regulatory network analysis identified candidate transcription factors regulating the CAM pathway and stomatal *** together,our results provide new insights into weak CAM photosynthesis and new avenues for CAM bioengineering.

关键词： Platycerium bifurcatum crassulacean acid metabolism multi-omics transcription factor PPCK convergent evolution