检索结果-南通市图书馆

An Integrated Approach for Optimal Design of Micro Gas Turbine Combustors

在线全文

学校读者我要写书评

暂无评论

Journal of Thermal Science 2009年第2期18卷 173-184页

作者： Luca Fuligno diego Micheli Carlo Poloni EnginSoft s.p.a. dipartimento di ingegneria meccanica Universita degli Studi di Trieste dipartimento

The present work presents an approach for the optimized design of small gas turbine combustors, that integrates a0-D code, CFD analyses and an advanced game theory multi-objective optimization algorithm. The output of the0-D code is a baseline design of the combustor, given the required fuel characteristics, the basic geometry (tubularor annular) and the combustion concept (i.e. lean premixed primary zone or diffusive processes). For the optimizationof the baseline design a simplified parametric CAD/mesher model is then defined and submitted to a CFDcode. Free parameters of the optimization process are position and size of the liner hole arrays, their total area andthe shape of the exit duct, while different objectives are the minimization of NOx emissions, pressure losses andcombustor exit Pattern Factor. A 3D simulation of the optimized geometry completes the design procedure. As afirst demonstrative example, the integrated design process was applied to a tubular combustion chamber with alean premixed primary zone for a recuperative methane-fuelled small gas turbine of the 100 kW class.

关键词： micro gas turbine combustor optimized design

Small heat shock protein B8:from cell functions to its involvement in diseases and potential therapeutic applications

在线全文

学校读者我要写书评

暂无评论

Neural Regeneration Research 2025年第10期20卷 2872-2886页

作者： Marta Chierichetti Riccardo Cristofani Valeria Crippa Veronica Ferrari Marta Cozzi Elena Casarotto Paola Pramaggiore Laura Cornaggia Guglielmo Patelli Ali Mohamed Margherita Piccolella Mariarita Galbiati Paola Rusmini Barbara Tedesco Angelo Poletti Laboratory of Experimental Biology Dipartimento di Scienze Farmacologiche e Biomolecolari“Rodolfo Paoletti”(DiSFeB)Universitàdegli Studi di MilanoMilanItaly

Heat shock protein family B(small)member 8(HSPB8)is a 22 kDa ubiquitously expressed protein belonging to the family of small heat shock ***8 is involved in various cellular mechanisms mainly related to proteotoxic stress response and in other processes such as inflammation,cell division,and ***8 binds misfolded clients to prevent their aggregation by assisting protein refolding or degradation through chaperone-assisted selective *** line with this function,the pro-degradative activity of HSPB8 has been found protective in several neurodegenerative and neuromuscular diseases characterized by protein misfolding and *** cancer,HSPB8 has a dual role being capable of exerting either a pro-or an anti-tumoral activity depending on the pathways and factors expressed by the model of cancer under ***,HSPB8 exerts a protective function in different diseases by modulating the inflammatory response,which characterizes not only neurodegenerative diseases,but also other chronic or acute conditions affecting the nervous system,such as multiple sclerosis and intracerebellar *** note,HSPB8 modulation may represent a therapeutic approach in other neurological conditions that develop as a secondary consequence of other *** is the case of cognitive impairment related to diabetes mellitus,in which HSPB8 exerts a protective activity by assuring mitochondrial *** review aims to summarize the diverse and multiple functions of HSPB8 in different pathological conditions,focusing on the beneficial effects of its ***-based and alternative therapeutic approaches targeting HSPB8 and its regulated pathways will be discussed,emphasizing how new strategies for cell and tissue-specific delivery represent an avenue to advance in disease treatments.

关键词： aggregation autophagy cancer chaperone chaperone-assisted selective autophagy cognitive impairment HSPB8 neuroinflammation neuromuscular diseases therapy

Voltage controlled iontronic switches:a computational method to predict electrowetting in hydrophobically gated nanopores

在线全文

学校读者我要写书评

暂无评论

International Journal of Smart and Nano Materials 2024年第1期15卷 165-185页

作者： Goncalo Paulo Alberto Gubbiotti Giovanni di Muccio Alberto Giacomello dipartimento di ingegneria meccanica e Aerospaziale Sapienza Universita di RomaRomeItaly

Reliable and controllable switches are crucial in nanofluidics and *** channels found in nature serve as a rich source of inspiration due to their intricate mechanisms modulated by stimuli like pressure,temperature,chemical species,and *** artifi-cial replication of the properties of these channels is challenging due to their complex chemistry,limited stability range,and intricate moving parts,allosterically ***,we can harness some of the gating mechanisms of ion channels for nanofluidic and iontronic *** theoretical and computational study explores the use of electrowetting in simple hydrophobic nanopores to control their conductance using an external applied *** employ restrained molecular dynamics to calculate the free energy required for wetting a model nanopore under different *** a simple theory,we generate free energy profles across a wide voltage *** also computed transition rates between conductive and non-conductive states,showing their voltage depen-dence and how this behavior can impair memory to the system,resembling the memristor behavior voltage-gated channels in the *** proposed framework provides a promising avenue for designing and controlling hydrophobic nanopores via electrowet-ting,enabling potential applications in neuromorphic iontronics.

关键词： Electrowetting lontronics hydrophobic gating

Modeling of shear induced coarsening effects in semi-solid alloys

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Transactions of Nonferrous Metals Society of China 2010年第9期20卷 1696-1701页

作者： M.MOdiGEL L A.POLA AVT Chair of Mechanical Process EngineeringRWTH Aachen University dipartimento di ingegneria meccanica e Industriale Uni.degli Studi di Brescia

In long-term rheological shear experiments with semi-solid alloys, coarsening of the particles will falsify the interpretation of the experimental *** coarsening is intensified by the shear induced convection and the mean size of the particles is changed significantly during the experiments.A simple model has been set up which takes the influence of the convection into *** resulting growth law has been simplified for diffusion and convection dominated *** growth law was verified with shear experiments in a Searl-rheometer with A356 and tin-lead *** experiments demonstrated that under convection the growth follows a linear time law and that the rate constant depends on the root of the shear *** correction of experimental results to gain the true viscosity function is demonstrated for a shear jump experiment with A356.

关键词： microstructure coarsening Ostwald ripening flow function viscosity rheology semi-solid alloys

Improving the Hydromechanical Deep-Drawing Process Using Aluminum Tailored Heat Treated Blanks

在线全文

学校读者我要写书评

暂无评论

Acta Metallurgica Sinica(English Letters) 2015年第12期28卷 1482-1489页

作者： Antonio Piccininni Gabriella di Michele Gianfranco Palumbo Donato Sorgente Luigi Tricarico dipartimento di meccanica Matematica e Management Politecnico di Bari

The present work demonstrates the effectiveness of combining the hydromechanical deep-drawing process with the Tailored Heat Treated Blank（THTB） technique. In the hydromechanical deep-drawing process, the fluid pressure is used for postponing the fracture occurrence in the blank, while the THTB technique allows to create a material property gradient through a suitable artificial aging treatment carried out prior to the forming process. Since the number of process variables is large, in the present work the authors propose an optimization loop for the determination of the parameters controlling the extension of the blank regions to be subjected to the aging treatment and the temperature levels to be set during the heat treatment. The proposed methodology couples a simple finite element model（Abaqus） with a multiobjective optimization platform（mode FRONTIER）. A preliminary experimental campaign was carried out for determining the effect of the aging treatment on the mechanical（through tensile tests） and deformative（through formability tests）behavior of the AC170 PX aluminum alloy. Optimization results prove the effectiveness of the adopted methodology and put in evidence that the adoption of properly aged blanks in the hydromechanical deep drawing allows to increase the limit drawing ratio and to simplify the process since it is conducted at room temperature.

关键词： Aluminum alloy Aging Hydromechanical deep drawing Finite element analysis Mechanical characterization Formability

Semisolid lead-antimony alloys for cars batteries

在线全文

学校读者我要写书评

暂无评论

Transactions of Nonferrous Metals Society of China 2010年第9期20卷 1774-1779页

作者： A.POLA M.GELFI M.M OdiGELL R.ROBERTI dipartimento di ingegneria meccanica e Industriale Università degli Studi di Brescia Aachener Verfahrenstechnik Chair of Mechanical Unit OperationsRWTH Aachen University

The application of semisolid process was investigated on Pb-Sb alloys that are normally used for metallic parts in car batteries, in order to increase their mechanical properties and corrosion *** semisolid behaviour of a Pb-4%Sb alloy was analysed by means of rheological and calorimetry differential scanning *** alloy was melted, treated by ultrasound to obtain the semisolid state and then poured into permanent *** of these samples were also heated in semisolid temperature range and injected in thixo-casting *** poured and injected samples were characterized by metallographic analysis, mechanical test and electrochemical corrosion *** results show an improvement of mechanical and corrosion resistance with respect to samples obtained by conventional casting technique.

关键词： Pb-based alloys semisolid metal corrosion resistance viscosity

On “Over-Sized” High-Gain Practical Observers for Nonlinear Systems

在线全文

学校读者我要写书评

暂无评论

IEEE/CAA Journal of Automatica Sinica 2018年第3期5卷 691-698页

作者： Daniele Carnevale Corrado Possieri Antonio Tornambè dipartimento di ingegneria Civile e ingegneria Informatica Universita di Roma Tor Vergata

In this paper,it is shown that the performances of a class of high-gain practical observers can be improved by estimating the time derivatives of the output up to an order that is greater than the dimension of the system, which is assumed to be in observability form and, possibly, time-varying. Such an improvement is achieved without increasing the gain of the observers, thus allowing their use in a wide variety of control and identification applications.

关键词： Filtering properties nonlinear systems observability observer design

Nonlinear Damped Oscillators on Riemannian Manifolds:Fundamentals

在线全文

学校读者我要写书评

暂无评论

Journal of Systems Science & Complexity 2016年第1期29卷 22-40页

作者： FIORI Simone dipartimento di ingegneria dell'Informazione Facolta di IngegneriaUniversita Politecnica delle Marche

The classical theory of mass-spring-damper-type dynamical systems on the ordinary flat space R^3 may be generalized to higher-dimensional Riemannian manifolds by reformulating the basic underlying physical principles through differential *** dynamical systems have been studied in the scientific literature because they arise naturally from the modeling of complex physical structures and because such dynamical systems constitute the basis for several modern applications such as the secure transmission of *** flows of nonlinear dynamical systems may evolve over time in complex,non-repeating(although deterministic) *** focus of the present paper is on formulating the general equations that describe the dynamics of a point-wise particle sliding on a Riemannian manifold in a coordinate-free *** paper shows how the equations particularize in the case of some manifolds of interest in the scientific literature,such as the Stiefel manifold and the manifold of symmetric positive-definite matrices.

关键词： Nonlinear(active/passive) damping nonlinear oscillator Riemannian manifold

Correlation of powder flow properties to interparticle interactions at ambient and high temperatures

在线全文

学校读者我要写书评

暂无评论

Particuology 2014年第1期12卷 90-99页

作者： Igino Tomasetta diego Barletta Massimo Poletto dipartimento di ingegneria Industriale Università degli Studi di Salerno

A combination of a continuum approach and a particleparticle approach to describe the multiscale nature of the mechanical properties of bulk solids may be beneficial to scientific and engineering applica tions. In this paper, a procedure is proposed to estimate the interparticle forces beginning with the bulk flow properties as measured with standardized techniques. In particular, the relationship between inter particle forces and bulk solid tensile strength is adopted based on the microscale approaches of Rumpf （1970） and Molerus （1975）. The flow properties of fluid cracking catalyst （FCC）, corundum and glass bead powders were all characterized with a modified Schulze ring shear cell capable of operating at tempera tures up to 500 ~C. The powder test conditions were selected such that the van der Waals forces were the most significant particleparticle interactions. The model equations describe two cases, in which either elastic or plastic deformation of the contact points is assumed. The results indicate that the model pro vides the correct order of magnitude for the values of the tensile strength when proper values for the mean curvature radius at the contact points are taken into account. A sensitivity analysis for the main parameters in the model was performed. This analysis indicated that the assumption of plastic deforma tion at contact surfaces coupled with a decrease in porosity justified an increase of the tensile strength with consolidation stress. Furthermore, the effect of temperature on the measured flow behavior can be explained as a change in the strength of the material.

关键词： Shear testingYield locusvan der Waals forcelnterparticle interactionsPowder consolidationHigh temperature