检索结果-南通市图书馆

An in vitro demonstration of a passive,acoustic metamaterial as a temperature sensor with mK resolution for implantable applications

引用

Microsystems & Nanoengineering 2024年第1期10卷 41-54页

作者： Lucrezia Maini Vicente Genovés Roman Furrer Nikola Cesarovic Christofer Hierold Cosmin Roman Micro-and Nanosystems Department of Mechanical and Process EngineeringETH ZurichTannenstrasse 38092 ZurichSwitzerland. Translational Cardiovascular Technology Department of Health Science and TechnologyETH ZurichLeopold-Ruzicka-Weg 48093 ZurichSwitzerland. Transport at Nanoscale Interfaces Swiss Federal Laboratories for Materials Science and TechnologyEMPAÜberlandstrasse 1298600 DübendorfSwitzerland Department of Cardiothoracic and Vascular Surgery Deutsches Herzzentrum der Charite(DHZC)13353 BerlinGermany

Wireless medical sensors typically utilize electromagnetic coupling or ultrasound for energy transfer and sensor *** transfer and management is a complex aspect that often limits the applicability of implantable sensor *** this work,we report a new passive temperature sensing scheme based on an acoustic metamaterial made of silicon embedded in a polydimethylsiloxane *** to other approaches,this concept is implemented without additional electrical components in situ or the need for a customized receiving unit.A standard ultrasonic transducer is used for this demonstration to directly excite and collect the reflected *** metamaterial resonates at a frequency close to a typical medical value(5 MHz)and exhibits a high-quality *** the design features of the metamaterial with the high-temperature sensitivity of the polydimethylsiloxane matrix,we achieve a temperature resolution of 30 *** value is below the current standard resolution required in infrared thermometry for monitoring postoperative complications(0.1 K).We fabricated,simulated,in vitro tested,and compared three acoustic sensor designs in the 29-43℃(~302-316 K)temperature *** this concept,we demonstrate how our passive metamaterial sensor can open the way toward new zero-power smart medical implant concepts based on acoustic interrogation.

关键词： passive resolution utilize

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Age-dependent impact of the SYNTAX-score on longer-term mortality after percutaneous coronary intervention in an all-comer population

引用

Journal of Geriatric Cardiology 2018年第9期15卷 559-566页

作者： Madeleine Eickhoff Stefanie Schupke Alexander Khandoga Julia Fabian Moritz Baquet David Jochheim David Grundmann Manuela Thienel Axel Bauer Hans Theiss Stefan Brunner Jorg Hausleiter Steffen Massberg Julinda Mehilli Department of Cardiology Munich University Clinic Ludwig-Maximilians University Munich Germany German Centre for Cardiovascular Research (DZHK) Partner Site Munich Heart Alliance Germany deutsches herzzentrum miinchen Klinik fiir Herz- und Kreislauferkrankungen ISAResearch Center Munich Germany

Background The Synergy between Percutaneous Coronary Intervention with TAXUS and Cardiac Surgery （SYNTAX）-score is a validated tool for risk stratification and revascularization strategy selection in patients with complex coronary artery disease. The aim of this study was to analyse its age-related prognostic value. Methods SYNTAX-score was calculated in 1331 all-comer patients undergoing percutaneous coronary intervention （PCI）： 463 patients ≥ 75 years and 868 patients 〈 75 years. Outcomes of interest were all-cause mortality at one and two years. Results A significant interaction of age and SYNTAX-score for mortality was observed at two-year （Pinteraction= 0.019） but not at one-year follow-up （Pinteraction= 0.594）. In multivariable analysis, SYNTAX-score independently predicted 1-year mortality in both age groups （〈 75 years, hazard ratio （HR）： 1.43, 95% confidence intervals （CI）： 1.03-2.00, P = 0.034; and 〉 75 years, HR： 1.37, 95% CI： 1.01-1.85, P = 0.042）, but only two-year mortality among younger patients （〈 75 years, HR： 1.33, 95% CI： 1.01-1.76, P = 0.041; and ≥ 75 years, HR： 1.11, 95% CI： 0.87-1.41, P = 0.394）. SYNTAX-score tertiles were useful to stratify 1-year mortality in both, patients 〈 75 years （SYNTAX-score 〈 9, 3.8%; 9-20, 5.3%; 〉 20, 10.3%; P = 0.004） and 〉 75 years （SYNTAX-score 〈 11, 5.7%; 11-22.5, 16.1%; 〉 22.5, 18.7%; P = 0.003）, but two-year mortality only among patients 〈 75 years （SYNTAX-score 〈 9, 6.5%; 9-20, 7.6%; ≥ 20, 15%; P 〈 0.001） and not among ≥ 75 years old patients （SYNTAX-score 〈 11, 19.4%; 11-22.5, 26.3%; _〉 22.5, 27.9%; P = 0.138）. Conclusions Age modi- fies the impact of the SYNTAX-score on longer-term mortality after PCI. Among patients 〈 75 years, the SYNTAX-score independently predicts the risk of death at one and two years after PCI, while among patients 〉 75 years its predictive role is limited to the first year after PCI. Further studies are needed to evaluate the value of SYNTAX-score for selecting the most appropriate re

关键词： Age Mortality Percutaneous coronary intervention Syntax-score The elderly

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Cardiac Lymphoma： After the Hurricane

引用

Chinese Medical Journal 2017年第19期130卷 2391-2392页

作者： Marijana Tadic Sabine HaSleld Burket Pieske Martin Genger Department of Cardiology Charite-University-Medicine Berlin 13353 Germany deutsches Zentrum for Herz-Kreislauf-Forschung Berlin 13353 Germany Department of Cardiology Deutsches Herzzentrum Berlin Berlin 13353 Germany

A71-year-old male patient with symptoms and signs of right heart failure was presented. Echocardiographic examination revealed a large tumor mass infiltrating predominantly the right atrium （RA）, tricuspid valve, an... 详细信息

关键词： CELL LYMPHOMA BLOCK

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Transcatheter aortic valve implantation for Chinese patients with bicuspid aortic valve

引用

Journal of Zhejiang University-Science B(Biomedicine & Biotechnology) 2015年第4期16卷 327-328页

作者： Yu-guo WENG deutsches herzzentrum Berlin Augustenburger Platz 113353 BerlinGermany

The recent paper by the corresponding author Jian-an WANG and his team entitled"Evaluation of the safety and efficacy of transcatheter aortic valve implantation in patients with a severe stenotic bicuspid aortic valve in a Chinese population"(Liu et al.,2015),published in the Journal of Zhejiang UniversitySCIENCE B(Biomedicine&Biotechnology),is very *** evaluated the safety and efficacy of transcatheter aortic valve implantation(TAVI)

关键词：主动脉患者中国植入导管浙江大学生物医药安全性

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Artificial sweetener sucralose: a possible modulator of autoimmune diseases

引用

Signal Transduction and Targeted Therapy 2023年第11期8卷 5123-5125页

作者： Nicolle Kränkel Ursula Rauch-Kroehnert deutsches herzzentrum der Charité Klinik für KardiologieAngiologie und IntensivmedizinCampus Benjamin-Franklin(CBF)12203BerlinGermany DZHK(German Centre for Cardiovascular Research) Partner site BerlinBerlinGermany Friede Springer—Centre of Cardiovascular Prevention@Charité Charité—University Medicine BerlinBerlinGermany

In their research article in Nature in March 2023,Fabio Zani and colleagues reported that high concentrations of the zero-calorie artificial sweetener sucralose affected the proliferation and differentiation of T cells toward interferon-γ-producing subsets,with no effect observed for B cells and myeloid cells.1 The publication has raised high hopes in the lay press on a widely available cure for patients suffering from autoimmune diseases.

关键词： autoimmune interferon diseases

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Replacement of degenerated prosthetic valve post apico-aortic conduit with extra corporeal membrane oxygenation

引用

Chinese Medical Journal 2012年第24期125卷 4528-4529页

作者： LONG Xiao-mao Knosalla Christoph Department of Thoracic and Cardiovascular Surgery Guangxi Pepole's Hospital Nanning Guangxi 530021 China Department of Cardiothoracic and Vascular Surgery Deutsches Herzzentrum Berlin Germany

Use of an apico-aortic conduit （AAC） serves as an alternative method to treat severe aortic stenosis inelder patients, especially in those with a heavily calcified ascending aorta or prior cardiac surgery. The results of long-term follow-up of AAC are very rare. We reported a case about a successful replacement of late degenerated prosthetic valve following AAC procedure, assisted with extra corporeal membrane oxygenation （ECMO）.

关键词： apico-aortic conduit extra corporeal membrane oxygenation prosthetic valve structure failure

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

阿昔单抗与冠状动脉支架置入术后血管造影显示再狭窄的关系:来自ISAR-REACT试验(一项安慰剂对照的随机双盲试验,旨在评估在给予高负荷剂量氯吡格雷后行择期经皮冠状动脉介入的患者使用阿昔单抗的作用)血管造影亚研究的分析

引用

世界核心医学期刊文摘（心脏病学分册） 2006年第11期2卷 13-14页

作者： Schühlen H. Kastrati A. Mehilli J. 尹涛 deutsches herzzentrum Munich Germany Dr.

Background: ISAR-REACT was a trial designed to evaluate whether the glycoprotein IIb/IIIa inhibitor abciximab is beneficial in patients undergoing elective percutaneous coronary intervention(PCI) with stent placement after pretreatment with a 600 mg loading dose of clopidogrel. Objective for the angiographic substudy was to determine the impact of abciximab on angiographic restenosis after coronary stent placement. Previous analyses have suggested a reduction in the incidence of restenosis after the administration of abciximab. Methods: The angiographic substudy comprises 1885 of 2159 patients enrolled in ISAR-REACT: 994 patients were randomly assigned to abciximab and 941 patients to placebo. All patients were scheduled for a routine angiographic follow-up after 6 months(performed in 80%of eligible patients). End points for the angiographic substudy were the rates of angiographic restenosis(≥50%diameter stenosis) and target lesion revascularization. Results: The incidence of angiographic restenosis was 27%in the abciximab group and 29%in the placebo group(relative risk 0.92, 95%CI 0.79-1.06, P=.27). Late angiographic lumen loss was 0.95±0.68 and 0.99±0.70 mm, respectively(P=.25). Similar results were obtained in a subgroup analysis focusing on high-risk subsets. The rate of target lesion revascularization procedures was 22%in the abciximab group and 23%in the placebo group(relative risk 0.94, 95%CI 0.79-1.12, P=.52). Conclusions: In low-to intermediate-risk patients who undergo elective PCI after pretreatment with a high loading dose of clopidogrel >2 hours before PCI, the additional administration of the glycoprotein IIb/IIIa inhibitor abciximab is not associated with a significant reduction in angiographic restenosis.

关键词：阿昔单抗 ISAR-REACT 负荷剂量再狭窄血管造影随机双盲靶病变血运重建安慰剂对照造

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

药物洗脱支架与细杆裸金属支架降低再狭窄的比较:一项前瞻性随机研究

引用

世界核心医学期刊文摘(心脏病学分册) 2006年第3期 46-47页

作者： Pache J. Dibra A. Mehilli J. A. Kastrati 刘宇 deutsches herzzentrum Lazarettstrasse 36 80636 Munich Germany

Aim: Drug-eluting stents have considerably reduced restenosis. Their relative merits have been assessed on the basis of comparisons made with control bare stents with thick struts. However, increased strut thickness negatively affects restenosis. No direct comparisons between drug-eluting stents and bare stents with thin struts have been performed. The aim of this study was to evaluate the relative efficacy of sirolimus-eluting stents(CypherTM) as compared with that of bare stents with thin struts(BeStentTM 2). Methods and results: A total of 500 patients with coronary artery disease were randomly assigned to receive a Cypher stent or BeStent. The primary endpoint was angiographic restenosis defined as a stenosis diameter ≥ 50% at 6-month angiographic follow-up. The secondary endpoint was the need for target vessel revascularization(TVR) during the year following the procedure. Follow-up angiography was performed in 81.8% of the patients. Patients treated with Cypher stents had a lower angiographic restenosis rate 8.3 vs. 25.5% , relative risk, 0.33(95% confidence interval, 0.19-0.56), P< 0.001 and a lower incidence of TVR 7.2 vs. 18.8% , relative risk, 0.38(0.22-0.66), P< 0.001 . For smaller vessels(< 2.8 mm), the angiographic restenosis rates were 7.0% with the Cypher stent and 34.2% with the BeStent(P< 0.001). For larger vessels(≥ 2.8 mm), angiographic restenosis rates were 10.0% with the Cypher stent and 13.1% with the BeStent(P=0.52). Conclusion: The drug-eluting stent, Cypher, is associated with a significantly lower risk of restenosis compared with the bare thin-strut BeStent. The advantage of the Cypher stent is vastly reduced in large vessels.

关键词：药物洗脱支架再狭窄金属支架矿山支架

来源：

同方期刊数据库评论

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

接受经皮冠状动脉介入的急性冠状动脉综合征患者中性别与阿昔单抗作用的关系:ISAR-REACT2试验的结果

引用

世界核心医学期刊文摘（心脏病学分册） 2007年第10期3卷 20-21页

作者： Mehilli J. Ndrepepa G. Kastrati A. 黄欣 deutsches herzzentrum Technische Universit t MunichGermany Dr.

背景:接受经皮冠状动脉介入(PCI)的急性冠状动脉综合征(ACS)患者中,阿昔单抗的临床作用是否存在性别差异尚不清楚。

关键词：阿昔单抗急性冠状动脉综合征经皮冠状动脉介入患者

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

关于急性心肌梗死患者中粒细胞集落刺激因子诱导干细胞动员的随机对照研究

引用

世界核心医学期刊文摘（心脏病学分册） 2006年第8期2卷 2-3页

作者： Zohlnhfer D. Ott I. Mehilli J. A. Schmig 任付先 deutsches herzzentrum Lazarettstrasse 36 80636 Munich GermanyDr.

Context: Experimental studies and early phase clinical trials suggest that transplantation of blood-derived or bone marrow-derived stem cells may improve cardiac regeneration and neovascularization after acute myocardial infarction. Granulocyte colony-stimulating factor(G-CSF) induces mobilization of bone marrow stem cells. Objective: To assess the value of stem cell mobilization by G-CSF therapy in patients with acute myocardial infarction. Design, Setting, and Patients: Randomized, double-blind, placebo-controlled trial of patients diagnosed with ST-segment elevation acute myocardial infarction who had successful reperfusion by percutaneous coronary intervention within 12 hours after onset of symptoms in Germany between February 24, 2004, and February 2, 2005. Interventions: Patients were randomly assigned to receive subcutaneously either a daily dose of 10 μ g/kg of G-CSF or placebo for 5 days. Main Outcome Measures: The primary end point was reduction of left ventricular infarct size according to technetium Tc 99m sestamibi scintigraphy performed at baseline and at 4 to 6 months after randomization. Secondary end points included improvement of left ventricular ejection fraction measured by magnetic resonance imaging and the incidence of angiographic restenosis. Results: Of the 114 patients, 56 were assigned to receive treatment with G-CSF and 58 were assigned to receive placebo. Treatment with G-CSF produced a significant mobilization of stem cells. Between baseline and follow-up, left ventricular infarct size according to scintigraphy was reduced by a mean(SD) of 6.2% (9.1% ) in the G-CSF group and 4.9% (8.9% ) in the placebo group(P=.56) and left ventricular ejection fraction was improved by 0.5% (3.8% ) in the G-CSF group and 2.0% (4.9% ) in the placebo group(P=.14). Angiographic restenosis occurred in 19(35.2% ) of 54 patients in the G-CSF group and in 17(30.9% ) of 55 patients in the placebo group(P=.79). The most common adverse event among patients assigne

关键词：粒细胞集落刺激因子急性心肌梗死后骨髓干细胞动员心肌梗死患者随机对照研究经皮冠状动脉介入治疗骨髓源性干细胞移植新生血管形成 ST段抬高型临床试验

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：