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Gadoxetic acid magnetic-enhanced resonance imaging in the diagnosis of cholangiocarcinoma

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World Journal of Gastroenterology 2020年第29期26卷 4261-4271页

作者： Riccardo Inchingolo Cesare Maino Marco Gatti Eleonora Tricarico Michele Nardella Luigi Grazioli SandroSironi Davide Ippolito Riccardo Faletti Division of Interventional radiology Department of RadiologyMadonna delle Grazie HospitalMatera 75100Italy Department of diagnostic radiology School of MedicineUniversity of Milano-BicoccaMonza 20900Italy Department of Surgical Sciences Radiology UnitUniversity of TurinTurin 10126Italy Department of radiology Spedali CiviliUniversity of BresciaBrescia 25123Italy Department of radiology Papa Giovanni XXIII HospitalUniversity Milano-BicoccaBergamo 20110Italy

The use of liver magnetic resonance imaging is increasing thanks to itsmultiparametric sequences that allow a better tissue characterization, and the useof hepatobiliary contrast agents. This review aims to evaluate gadoxetic acidenhanced magnetic resonance imaging in the diagnosis and staging ofcholangiocarcinoma and its different clinical and radiological classificationsproposed in the literature. We also analyze the epidemiology, risk factors incorrelation with clinical findings and laboratory data.

关键词： Hepatobiliary contrast materials Gadoxetic acid Cholangiocarcinoma Magnetic resonance imaging Liver Cirrhosis

Endovascular management of carotid-cavernous fistulas

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介入放射学杂志 2007年第1期16卷 4-9页

作者： GAO Bu-lang LI Ming-hua LI Yong-dong FANG Chun WANG Jue DU Zhuo-ying Department of diagnostic andInterventional radiology Shanghai Sixth People＇s Hospital ShanghaiJiaotong University School of Medicine200233

Objective To investigate endovascular treatment of traumatic direct carotid-cavernous fistulas (CCF) and their complications such as pseudoaneurysms. Methods: Over a five-year period, 22 patients with traumatic direct CCFs were treated endovascularly in our institution. Thirteen patients were treated once with the result of CCF occluded, 8 twice and 1 three times. Treatment modalities included balloon occlusion of the CCF, sacrifice of the ipsilateral internal carotid artery with detachable balloon, coil embolization of the cavernous sinus and secondary pseudoaneurysms, and covered-stent management of the pseudoaneurysms. Results All the direct CCFs were successfully managed endovascularly. Four patients developed a pseudoaneurysm after the occlusion of the CCF with an incidence of pseudoaneurysm formation of 18.2% (4/22). A total number of 8 patients experienced permanent occlusion of the ICA with a rate of ICA occlusion reaching 36.4% (8/22). Followed up through telephone consultation from 6 months to 5 years, all did well with no recurrence of CCF symptoms and signs. Conclusion Traumatic direct CCFs can be successfully managed with endovascular means. The pseudoaneurysms secondary to the occlusion of the CCFs can be occluded with stent-assisted coiling and implantation of covered stents.

关键词： Carotid-cavernous fistula Trauma Endovascular managemeat

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Developments in diagnosis and management of post-liver transplantation biliary complications:the radiologist’s perspective

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Hepatobiliary Surgery and Nutrition 2022年第3期11卷 457-461页

作者： Paolo Marra Pietro Andrea Bonaffini Davide Ippolito Sandro Sironi Department of radiology Papa Giovanni XXIII HospitalBergamoItaly School of Medicine University of Milano-BicoccaMilanItaly Department of diagnostic radiology San Gerardo HospitalMonzaItaly

Biliary complications are the most common source of morbidity after liver transplantation as they may occur in up to 45%of patients(1).The review by Magro et al.(2)provides comprehensive insights on this topic and offers a cue for in-depth remarks form a radiological perspective regarding both diagnostic and interventional ***(US)-based techniques,including B-mode and color-Doppler,are the milestone of post-transplant *** assessment of graft vascularization is crucial since many biliary complications are supposed to be induced by arterial *** this regard,however,it must be emphasized that US imaging is hampered by a limited panoramic view,especially in difficult abdomens,therefore it is not possible to rely exclusively on this technique.

关键词： diagnosis complications graft

Computed tomography radiogenomics:A potential tool for prediction of molecular subtypes in gastric stromal tumor

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World Journal of Gastrointestinal Oncology 2024年第4期16卷 1296-1308页

作者： Xiao-Nan Yin Zi-Hao Wang Li Zou Cai-Wei Yang Chao-Yong Shen Bai-Ke Liu Yuan Yin Xi-Jiao Liu Bo Zhang Gastric Cancer Research Center West China HospitalSichuan UniversityChengdu 610041Sichuan ProvinceChina Department of Paediatric Surgery West China Hospital of Sichuan UniversityChengdu 610041Sichuan ProvinceChina Department of radiology West China HospitalSichuan UniversityChengdu 610041Sichuan ProvinceChina Department of Gastrointestinal Surgery Sichuan University West China HospitalChengdu 610041Sichuan ProvinceChina

BACKGROUND Preoperative knowledge of mutational status of gastrointestinal stromal tumors(GISTs)is essential to guide the individualized precision *** To develop a combined model that integrates clinical and contrast-enhanced computed tomography(CE-CT)features to predict gastric GISTs with specific genetic mutations,namely KIT exon 11 mutations or KIT exon 11 codons 557-558 *** A total of 231 GIST patients with definitive genetic phenotypes were divided into a training dataset and a validation dataset in a 7:3 *** models were constructed using selected clinical features,conventional CT features,and radiomics features extracted from abdominal CE-CT *** models were developed:ModelCT sign,modelCT sign+rad,and model CTsign+rad+*** diagnostic performance of these models was evaluated using receiver operating characteristic(ROC)curve analysis and the Delong *** The ROC analyses revealed that in the training cohort,the area under the curve(AUC)values for model_(CT sign),model_(CT sign+rad),and modelCT_(sign+rad+clinic)for predicting KIT exon 11 mutation were 0.743,0.818,and 0.915,*** the validation cohort,the AUC values for the same models were 0.670,0.781,and 0.811,*** predicting KIT exon 11 codons 557-558 deletions,the AUC values in the training cohort were 0.667,0.842,and 0.720 for model_(CT sign),model_(CT sign+rad),and modelCT_(sign+rad+clinic),*** the validation cohort,the AUC values for the same models were 0.610,0.782,and 0.795,*** on the decision curve analysis,it was determined that the model_(CT sign+rad+clinic)had clinical significance and *** Our findings demonstrate that the combined modelCT_(sign+rad+clinic)effectively distinguishes GISTs with KIT exon 11 mutation and KIT exon 11 codons 557-558 *** combined model has the potential to be valuable in assessing the genotype of GISTs.

关键词： Gastrointestinal stromal tumor Radiomics Gene mutation Computed tomography Model

Fulminant isolated cardiac sarcoidosis with pericardial effusion and acute heart failure: Challenging aspects of diagnosis and treatment

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World Journal of Clinical Cases 2016年第3期4卷 76-80页

作者： Nina Fluschnik Gunnar Lund Peter Moritz Becher Stefan Blankenberg Kai Muellerleile Department of General and Interventional Cardiology University Heart Center Department of diagnostic and Interventional radiology University Medical Center Hamburg Eppendorf

This case report illustrates challenging aspects of diagnosis and treatment of isolated sarcoid heart disease(SHD) and the role of cardiovascular magnetic resonance(CMR) imaging. Here, we present a previously healthy 45-year-old man, who was admitted with pericardial effusion and symptoms of acute heart failure. CMR followed by targeted left ventricular endomyocardial biopsy(EMB) revealed the diagnosis of isolated SHD. The combined use of CMR and EMB was crucial in diagnosing SHD. Furthermore, this case report demonstrates the value of CMR for monitoring response to therapy and lesion healing.

关键词： Heart failure Cardiac sarcoidosis Cardiovascular magnetic resonance imaging Endomyocardial biopsy Internal cardiac defibrillator

Image features of two rare mediastinal tumors: schwannoma of intrathoracic phrenic nerve and clear cell chondrosarcoma of the rib

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中华医学杂志(英文版) 2005年第17期 87-90页

作者： Ting-Kai Leung,Chien-Jui Cheng,Chi-Ming Lee,Hung-Jung Wang,Ya-Yen Chen diagnostic radiology Department of Taipei Medical University Hospital Taipei Medical University Taipei China Pathology Department of Taipei Medical University Hospital TaipeiMedical University Taipei China diagnostic radiology Department of Taipei Medical University Hospital Taipei Medical University Taipei China diagnostic radiology Department of Taipei Medical University Hospital Taipei Medical University Taipei China diagnostic radiology Department of Taipei Medical University Hospital Taipei Medical University Taipei China

Comparison of RECIST version 1.0 and 1.1 in assessment of tumor response by computed tomography in advanced gastric cancer

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Chinese Journal of Cancer Research 2013年第6期25卷 689-694页

作者： Gil-Su Jang Min-Jeong Kim Hong-Il Ha Jung Han Kim Hyeong Su Kim Sung Bae Ju Dae Young Zang Department of Internal Medicine Hallym University Sacred Heart Hospital Department of diagnostic radiology Hallym University Sacred Heart Hospital Department of Internal Medicine Kangnam Sacred Heart Hospital

Objective： Response Evaluation Criteria in Solid Tumors （RECIST） guideline version 1.0 （RECIST 1.0） was proposed as a new guideline for evaluating tumor response and has been widely accepted as a standardized measure. With a number of issues being raised on RECIST 1.0, however, a revised RECIST guideline version 1.1 （RECIST 1.1） was proposed by the RECIST Working Group in 2009. This study was conducted to compare CT tumor response based on RECIST 1.1 vs. RECIST 1.0 in patients with advanced gastric cancer （AGC）. Methods： We reviewed 61 AGC patients with measurable diseases by RECIST 1.0 who were enrolled in other clinical trials between 2008 and 2010. These patients were retrospectively re-analyzed to determine the concordance between the two response criteria using the κ statistic. Results： The number and sum of tumor diameters of the target lesions by RECIST 1.1 were significantly lower than those by RECIST 1.0 （P〈0.0001）. However, there was excellent agreement in tumor response between RECIST 1.1 and RECIST 1.0 0（κ=0.844）. The overall response rates （ORRs） according to RECIST 1.0 and RECIST 1.1 were 32.7% （20/61） and 34.5% （20/58）, respectively. One patient with partial response （PR） based on RECIST 1.0 was reclassified as stable disease （SD） by RECIST 1.1. Of two patients with SD by RECIST 1.0, one was downgraded to progressive disease and the other was upgraded to PR by RECIST 1.1. Conclusions： RECIST 1.1 provided almost perfect agreement with RECIST 1.0 in the CT assessment of tumor response of AGC.

关键词： Response Evaluation Criteria in Solid Tumors guideline version 1.0 (RECIST 1.0) ResponseEvaluation Criteria in Solid Tumors guideline version 1.1 (RECIST 1.1) gastric cancer tumor response

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Diffusion-weighted MRI in abdominal oncology:Clinical applications

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World Journal of Gastroenterology 2010年第7期16卷 832-836页

作者： Reiji Sugita Kei Ito Naotaka Fujita Shoki Takahashi Department of radiology Sendai City Medical CenterSendai 983-0824Japan Department of Gastroenterology Sendai City Medical CenterSendai 983-0824Japan Department of diagnostic radiology Graduate School of MedicineTohoku UniversitySendai 980-8574Japan

Diffusion-weighted magnetic resonance imaging(DWI) provides image contrast that is different from that obtained by conventional magnetic resonance *** previously,DWI has been used to evaluate various diseases of the central nervous system,several technical advances have expanded the clinical applications of DWI beyond the central nervous *** a result,many reports have been published on the use of DWI in abdominal ***,abdominal DWI has now being focused on evaluation of patients with abdominal *** can be used for pretreatment tumor detection,characterization including predicting tumor response to therapy,monitoring tumor response during therapy,and follow-up study after treatment to detect possible tumor recurrence.

关键词： Diffusion weighted magnetic resonance imaging Abdominal neoplasms

An unusual cause of acute anemia in an immunosuppressed patient

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Gastroenterology Report 2016年第3期4卷 254-256,I0003页

作者： Jamak Modaresi Esfeh Whitney Jackson Kianoush Ansari-Gilani Brian Putka Department of Gastroenterology&Hepatology Cleveland ClinicClevelandOHUSA Department of diagnostic radiology Washington UniversitySt.LouisMOUSA

Gastrointestinal mucormycosis is an uncommon,invasive,opportunistic fungal infection with a high mortality rate,seen more commonly in immunocompromised *** lethal infection has a wide range of presentations,from colonization of peptic ulcers to infiltrative disease and eventually vascular *** we present a case of upper gastrointestinal bleeding in an immunocompromised patient,which was proved to be secondary to gastric involvement by mucormycosis.

关键词： gastrointestinal bleeding gastric mucormycosis