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LncRNA SNHG11 promotes malignant progression of colorectal cancer cells through the PI3K/Akt/mTOR signaling pathway

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China med.cal Abstracts(Internal med.cine) 2024年第2期41卷 104-105页

作者：陶绍能 dept.Nucl med 1st Affil HospWannan Med CollWuhu 241000

Objective To investigate the effects of lncRNA SNHG11 on proliferation,migration,invasion and apoptosis of colorectal cancer cancer cells and possible *** qRT-PCR was performed.to detect the expression level of lncRNA... 详细信息

关键词： invasion colorectal cancer

Prognostic stratification of baseline PET metabolic parameters combined with Bcl-2/c-Myc dual expression in patients with primary gastrointestinal diffuse large B-cell lymphoma

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China med.cal Abstracts(Internal med.cine) 2024年第1期41卷 45-46页

作者：蒋冲 dept.Nucl med Nanjing Drum Tower HospNanjing Univ Med SchNanjing 210008

Objective To explore whether baseline PET metabolic parameters combined with B-cell lymphoma-2(Bcl-2)/cellular-myelocytomatosis viral oncogene (cMyc) dual expression (DE) can improve the prognostic stratification of p... 详细信息

关键词： lymphoma patients gastrointestinal

Prediction models for respiratory event types in OSA patients based on hypoxic parameters

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China med.cal Abstracts(Internal med.cine) 2024年第1期41卷 41-42页

作者：彭程 dept.Respir&Critical Care med Tianjin Med Univ General HospTianjin 300052

Objective To analyze the hypoxic parameters in patients with obstructive sleep apnea (OSA),to explore the difference and association between different types of respiratory events and to construct predictive models for respiratory event *** Fifty patients [including41 males and 9 females with age 18-74 (45.72±13.39) years] with OSA diagnosed by polysomnography(PSG) were selected for retrospective analysis.

关键词： patients respiratory hypoxic

Hemodynamic changes with serial balloon pulmonary angioplasty in chronic thromboembolic pulmonary hypertension

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China med.cal Abstracts(Internal med.cine) 2024年第2期41卷 99-100页

作者：汪薇 dept.Respir&Critical Care med Beijing Chaoyang HospCapital Med UnivBeijing Instit Respir MedBeijing 100020

Objective To monitor hemodynamic changes during serial balloon pulmonary angioplasty (BPA) for chronic thromboembolic pulmonary hypertension (CTEPH).Methods General clinical data of CTEPH patients diagnosed from October 2017 to January 2022 in Beijing Chaoyang Hospital were collected,and 83 patients who underwent at least 1 BPA treatment were included to analyze their 6 min walking distance,WHO functional class,N-terminal B-type natriuretic peptide precursor(NT-proBNP),troponin I (cTnI) and haemodynamic indices.

关键词： balloon hypertension angioplasty

Clinical features analysis of B-cell acute lymphoblastic leukemia with KMT2A::AFF1 gene expression

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China med.cal Abstracts(Internal med.cine) 2024年第1期41卷 60-61页

作者：张春玲 dept.Lab med Shanghai General HospShanghai 200080

Objective To analyze the correlation between clinical features and prognosis or prognostic risk factors in patients with KMT2A::AFF1 gene positive *** Retrospective cohort study was conducted.167cases of B-ALL admitted to the Shanghai General Hospital and the Naval med.cal University Affiliated First Hospital from April 1,2011 to July 31.

关键词： admitted prognosis clinical

Study on mechanism of Shenqu Zhuyu decoction in improving varicocele rats spermatogenesis based on PINK1/Parkin med.ated mitophagy and apoptosis

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China med.cal Abstracts(Internal med.cine) 2024年第2期41卷 75-76页

作者：张芳 dept.Centr Lab 5th Clin Med CollShanxi Med UnivTaiyuan 030012

Objective To observe the effect of the Shenqu Zhuyu Decoction(SZD)on varicocele(VC)rats mitophagy and apoptosis in left testis based on PTENinduced putative kinase 1(PINK1)/E3 ubiquitin protein ligase(Parkin)signaling pathway,and to explore its *** Totally 36 male SD rats were randomly divided into sham operation group,model group and SZD group,12 rats in each *** rats model was established by partial ligation of the left renal vein in model group and SZD *** 48th day after successful molding,the rats in SZD group were treated with SZD(0.7 g/100 g)by gavage,and rats in sham operation group and model group were given the equal volume of normal saline by gavage,twice a day for 60 days.

关键词： PINK1 Parkin apoptosis

Overexpression of tuftelin and KLF-5 and its clinicopathological features in hepatitis B virusrelated hepatocellular carcinoma

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China med.cal Abstracts(Internal med.cine) 2024年第2期41卷 86-87页

作者：杨君伶 Clin med.Res Center Affil Hosp&Dept ImmunolMed SchNantong UnivNantong 226001

Objective To analyze and evaluate the expressions and clinical value of tuftelin (TUFT1) and Krüppel-like factor 5 (KLF5) in hepatitis B virus (HBV)-related hepatocellular carcinoma(HCC) *** KLF5mRNA and TUFT1 mRNA transcriptional status in cancer and non-cancer groups were compared according to the Cancer Genome Atlas(TCGA) *** differences and prognostic value between the groups were analyzed.

关键词： clinic hepatocellular pathological

Clinical heterogeneity and cluster analysis of multiple system atrophy

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China med.cal Abstracts(Internal med.cine) 2024年第2期41卷 124-125页

作者：王雪梅 dept.Neurol Beijing Luhe HospCapital Med UnivBeijing 101149

Objective To examine the clinical subtypes of patients with multisystem atrophy(MSA)that may indicate the prognosis of ***,we aim to compare the ability to perform daily activities among patients of each subtype using cluster *** The retrospective analysis included demographic data,clinical symptoms and signs,scale scores,and ancillary examinations of 94 patients diagnosed with multisystem atrophyatXuanwu Hospital of Capital med.cal *** study aimed.to analyze the clinical characteristicssofeachhsubtype obtained through ***,acomparison was'made between patients with traditional motor subtypes and those with new subtypes in terms of activities of daily *** study consisted of 94 MSA patients,with an average age of 61 years and a female representation of 51.1%.Using the data collected on the continuum,a full linkage hierarchical cluster analysis was performed.to classify MSA patients into four clinical subtypes:gait disorder(17 cases,18.1%),malignant tonic hyperkinetic with premature haircut(25 cases,26.6%),intermed.ate(43 cases,45.7%)。

关键词： atrophy cluster analysis

Metagenomic next-generation sequencing for the diagnosis of Pneumocystis jirovecii pneumonia after allogeneic hematopoietic stem cell transplantation

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China med.cal Abstracts(Internal med.cine) 2024年第2期41卷 122-123页

作者：符蓉 dept.Hematol Nanfang HospSouth Med UnivClin Med Res CenterHematol DisGuangdong ProvGuangzhou 510515

Objective To investigate the value of metagenomic next-generation sequencing (mNGS) in the diagnosis of Pneumocystis jirovecii pneumonia (PJP) in patients undergoing allogeneic hematopoietic stem cell transplantation (allo-HSCT).Methods The data of 98patients with suspected pulmonary infection after alloHSCT who underwent pathogen detection from bronchoalveolar lavage fluid between June 2016 and August 2023 at Nanfang Hospital were analyzed.

关键词： diagnosis Pneumocystis pneumonia