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China Medical Abstracts(Internal Medicine) 2024年第1期41卷 2-3页

作者：钟文新 dept radiol Huazhong Univ Sci&Technol Union Shenzhen HospShenzhen 518052

Objective To establish and verify a nomogram model based on MRI liver imaging reporting and data system (LI-RADS) features for predicting microvascular invasion (MVI) in hepatocellular carcinoma (HCC)following the Milan criteria.Methods A retrospective analysis was conducted on data from 118 HCC patients(121 lesions) confirmed by pathology from June 2016 to June 2022 at the Third Affiliated Hospital of Soochow University.

关键词： invasion hepatocellular microvascular

The value of high-resolution CT visual scoring and quantitative analysis for the assessment of pulmonary Langerhans cell histiocytosis in adults

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China Medical Abstracts(Internal Medicine) 2024年第1期41卷 1-1页

作者：王金华 dept radiol PUMC&CAMSBeijing 100730

Objective To explore the value of high-resolution CT (HRCT) visual scores and quantitative analysis in assessing pulmonary Langerhans cell histiocytosis(PLCH) in adults.Methods In total 51 adult patients with PLCH confirmed by pathology in Peking Union Medical College Hospital from August 2014 to December2021 were retrospectively analyzed.All patients underwent HRCT and pulmonary function tests (PFT).

关键词： Langerhans histiocytosis pathology

CT volume measurement for prognostic evaluation of unresectable hepatocellular carcinoma after TACE

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World Journal of Gastroenterology 2010年第16期16卷 2038-2045页

作者： Zhang, Jia-Wen Feng, Xiao-Yuan Liu, Han-Qiu Yao, Zhen-Wei Yang, Yan-Mei Liu, Bin Yu, Yong-Qiang Fudan Univ Huashan Hosp Dept Radiol Shanghai 200040 Peoples R China Anhui Med Univ Affiliated Hosp 1 Dept Radiol Hefei 200040 Anhui Peoples R China

AIM:To analyze the value of computed tomography(CT) volume measurements for evaluation of the survival rate of unresectable hepatocellular carcinoma(HCC) patients after transcatheter arterial chemoembolization(TACE).METHODS:One hundred and sixty-six unresectable HCC patients after TACE were involved in this retrospective study.Hepatic CT scan was performed for all patients before and 4 wk to 2 mo after TACE to def ine the morphologic features of HCC including its largest diameter,volume,product of the greatest axial dimension,tumor to liver volume ratio(TTLVR),and tumor shrinkage ratio.Clinical variables used in the study included gender,age,pattern of tumor growth,number of lesions,Child-Pugh classif ication of liver function,repeated TACE times,pre-or post-treatment α-fetoprotein(AFP) level,portal vein cancerous thrombus,tumor metastasis,degree of lipiodol retention within the tumor,and percutaneous ethanol injection.The correlation between survival time and clinical variables of patients or lesions was analyzed by combining morphologic features with the corresponding clinical and general data as input.A Cox proportional hazard model was used to analyze prognostic factors.The Kaplan-Meier method was used to calculate the cumulative survival time.In? uence of the parameters on prognosis was analyzed by the log-rank test.RESULTS:The overall 6,12,24,36 and 60 mo cumulative survival rates were 78.92%,49.85%,23.82%,15.60% and 8.92%,respectively.The median survival time was 12 mo.Univariate and multivariate analysis showed that only 4 parameters were the independent prognostic factors including TTLVR(χ2 = 14.328,P < 0.001),portal vein cancerous thrombus(χ2 = 5.643,P = 0.018),repeated TACE times(χ2 = 8.746,P = 0.003),and post-treatment serum AFP level(χ2 = 5.416,P = 0.020).When the TTLVR value was less than 70%,the survival time was inversely correlated with the TTLVR value.CONCLUSION:CT volume measurement technique can predict the prognosis of unresectable HCC patients after TACE.

关键词： Hepatocellular carcinoma Chemoembolization Tumor volume Computed tomography Prognosis

radiological diagnosis of duodenocaval fistula:A case report and literature review

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World Journal of Gastroenterology 2010年第18期16卷 2314-2316页

作者： Guo, Yong Zhang, Yan-Qun Lin, Wei Gen Navy Hosp Dept Radiol Beijing 100048 Peoples R China

Duodenocaval fistula(DCF) is an uncommon but lethal clinical entity.The high mortality has been attributed to the difficulty of diagnosis before attempts at definitive therapy.In this case report,we describe a patient with a series of computed tomography(CT) examinations over a 2-mo period in hospital.A low-density air bubble appeared in the inferior vena cava(IVC) on the second day in hospital and became clear on day 19,and gradually enlarged.Magnetic resonance imaging(MRI) also clearly demonstrated a high-signal enteric contrast medium or thrombus and signal-void air bubbles in the IVC.However,cavography did not show the filling defect.We suggest that noninvasive CT and MRI should be chosen as a first-line investigation,and IVC,including the surrounding structures,should be carefully reviewed on images if DCF is clinically considered.

关键词： Duodenocaval fi stula Computed tomography Magnetic resonance imaging

Multi-slice spiral CT angiography in evaluating donors of living-related liver transplantation

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Hepatobiliary & Pancreatic Diseases International 2007年第4期6卷 364-369页

作者： Chen, Wen-Hua Xin, Wei Wang, Jie Huang, Qing-Juan Sun, Yi-Fang Xu, Qing Yu, Sheng-Nan Suzhou Univ Affiliated Hosp 3 Dept Radiol Changzhou 213003 Peoples R China Nanjing Med Univ Affiliated Hosp 1 Dept Radiol Nanjing 210029 Peoples R China

BACKGROUND: During the past years, the number of liver transplantation has increased greatly, but the number of available organs has not increased. In view of the critical shortage of organs, the indications for living-related liver transplantation (LRLT) have broadened since experience with the procedure has been achieved. This study was undertaken to assess the value of multi-slice spiral CT (MSCT) angiography in evaluating the hepatic arterial and veinous anatomy of potential donors for LRLT. METHODS: MSCT was performed after intravenous injection of contrast material at 3 ml/s. The total dose was calculated as 2 ml/kg. Twenty LRLT donors (2 men and 18 women) were subjected to MSCT angiography of hepatic blood vessels. These were generated by volume rendering and maximum intensity projection, while curved planar reformation was added in 5 patients. RESULTS: We identified 10 important hepatic vascular variants in 9 of the 20 donors (4 arterial, 4 venous, and 2 portal venous variants). In hepatic arterial variants, two had a replaced right hepatic artery arising from the superior mesenteric artery, an accessory right hepatic artery from the superior mesenteric artery and a replaced left hepatic artery arising from the left gastric artery. In hepatic venous variants, three had an accessory inferior right hepatic vein and one had two accessory inferior right hepatic veins. In hepatic portal venous variants, two had trifurcation of the main portal vein. CONCLUSIONS: As a non-invasive and reliable method, MSCT angiography is of value in the clinical evaluation of LRLT donors. MSCT angiography should be recommended as a routine preoperative examination for potential LRLT donors.

关键词： multi-slice spiral CT living-related liver transplantation donor angiography

Detection and characterization of hepatocellular carcinoma in rats with liver cirrhosis:diagnostic value of combined use of MR positive and negative contrast agents

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Hepatobiliary & Pancreatic Diseases International 2009年第1期8卷 65-70页

作者： Guo, Dong-Mei Qiu, Tian-Shuang Bian, Jie Liu, Shu-Feng Wang, Chang-Zheng Dalian Univ Technol Dept Elect Engn Dalian 116024 Peoples R China Dalian Med Univ Affiliated Hosp 2 Dept Radiol Dalian 116027 Peoples R China People Hosp Lvshun Dist Dept Radiol Dalian 116041 Peoples R China

BACKGROUND: Gadolinium-enhanced multi-phase dynamic imaging has improved the accuracy of the diagnosis of hypervascular hepatocellular carcinoma (HCC), but using gadolinium-enhanced dynamic imaging alone is problematic in evaluating hypovascular HCC. This work aimed at evaluating the combined use of superparamagnetic iron oxide (SPIO)-enhanced and gadolinium set in distinguishing HCCs from regenerative nodules (RNs) in a rat model induced by diethylnitrosamine (DEN). METHODS: DEN-induced HCC model rats (n=40) and control rats (n=10) were studied. From weeks 16 to 19 after DEN administration, 4 animals were scanned every week. The hepatic changes were tested with a 1.5 Tesla magnet, and MR images of SPIO-enhanced and gadolinium set were obtained. According to the pathologic changes, the tumorigenesis was divided into HCC and RN (diameter of nodules >= 3 mm). Diagnostic accuracy of the combined SPIO-enhanced and gadolinium set and the gadolinium set alone was evaluated using receiver-operating characteristic curves. Sensitivity and specificity of the combined SPIO-enhanced and gadolinium set and the gadolinium set alone were calculated. RESULTS: The listed tests were completed in 29 rats (21 treated and 8 controls). One hundred and six nodules (82 HCCs, 24 RNs) were analyzed. The Az value and sensitivity with the combined SPIO-enhanced and gadolinium set (Az 0.94, sensitivity 0.96) were higher than those with the gadolinium set alone (Az 0.92, sensitivity 0.89). Using the combined SPIO-enhanced and gadolinium set led to detection of 6 nodules which were negative in the gadolinium set alone and 3 nodules were correctly characterized. CONCLUSION: Using the combined SPIO-enhanced and gadolinium set improved the detectability of HCCs and the SPIO-enhanced imaging compensated for the gadolinium set in differentiating HCCs from RNs in a rat model.

关键词： iron oxides gadolinium magnetic resonance imaging hepatocellular carcinoma animal model

Magnetic resonance imaging-guided percutaneous cryoablation of hepatocellular carcinoma in special regions

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Hepatobiliary & Pancreatic Diseases International 2010年第4期9卷 384-392页

作者： Wu, Bin Xiao, Yue-Yong Zhang, Xiao Zhang, Ai-Lian Li, Hong-Jun Gao, Deng-Fa Chinese Peoples Liberat Army Gen Hosp Dept Radiol Beijing 100853 Peoples R China

BACKGROUND: Local cryoablation guided by CT or ultrasound has been widely applied in the treatment of hepatocellular carcinoma. However, it is still difficult to apply this technique in certain regions such as the diaphragm dome, the first hepatic hilum, and regions adjacent to the gallbladder. This study aimed to evaluate the safety and efficacy of using magnetic resonance imaging (MRI)-guided percutaneous cryoablation as well as the effect of using an open MRI system in guiding and monitoring the treatment of hepatocellular carcinoma in these regions. METHODS: Cryoablation, guided by an open 0.35T MRI scanner and with the assistance of an MRI-compatible optical navigation system, was performed on 32 patients with hepatocellular carcinoma at the diaphragm dome, the first hepatic hilum, and regions adjacent to the gallbladder. Each patient had one or two tumors. The total number of tumors treated was 36. The tumor diameters ranged from 2.5 to 10.0 cm (mean 4.7+/-1.8 cm). The cryosurgical system was MRI-compatible and equipped with cryoprobes 1.47 mm in outside diameter. Under the guidance of MRI in combination with the optical navigation system, the cryoprobes were introduced percutaneously into a tumor at the planned targeting points while critical organs or tissues were avoided. Each cryoablation procedure included two freezing-thawing cycles, and MRI images were acquired dynamically to monitor the ablation of the tumor from time to time during the operation. In order to investigate the therapeutic effects of a cryoablation procedure, AFP measurements and liver-enhanced MRI or CT-enhanced scans were performed at regular times. RESULTS: MRI and optical navigation system-guided cryoablation procedures were successfully performed on all 32 patients (36 tumor sites) and no serious complications occurred. The follow-up period ranged from 5 to 12 months. The 6- and 12-month overall survival rates were 96.8% and 90.6%, respectively. According to the diagnosis of liver-enhanced MRI scans, 10 patients (31.3%) had comple

关键词： magnetic resonance imaging interventional cryosurgery carcinoma, hepatocellular

Pleomorphic xanthoastrocytoma in the lateral ventricle with extensive subarachnoid dissemination： report of a case and review of the literature

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Chinese Medical Journal 2012年第2期125卷 396-399页

作者： Yang Wan-qun Huang Biao Liang Chang-hong Guangdong Acad Med Sci Guangdong Gen Hosp Dept Radiol Guangzhou 510080 Guangdong Peoples R China

Pleomorphic xanthoastrocytoma （PXA） is a rare benign tumor that is usually located in the superficial cerebral hemisphere.Most reports of PXAs have included only a single case or small series.Therefore,the data with respect to the natural history of this tumor are fragmentary.We report a case of a PXA in the unusual location of the right lateral ventricle with extensive subarachnoid dissemination.To our knowledge,this is a rare case of PXA in the lateral ventricle.In addition,extensive subarachnoid space dissemination of this distinctly benign type of glioma is exceedingly rare.In our case,there was meningeal dissemination and metastases to the bilateral trigeminal nerves and oculomotor nerves.The neuroradiographic features,tumor location,and dissemination were reviewed.

关键词： pleomorphic xanthoastrocytoma brain neoplasms lateral ventricles metastasis

Three-dimensional dynamic contrast-enhanced MR angiography for evaluating recipient vessels in orthotopic liver transplantation

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Hepatobiliary & Pancreatic Diseases International 2008年第5期7卷 476-480页

作者： Bian, Jie Sha, Lin Yang, Chao Sun, Chuan-Shu Dalian Med Univ Affiliated Hosp 2 Dept Radiol Dalian 116027 Peoples R China

BACKGROUND: With the improvement of MR technology, three-dimensional dynamic contrast-enhanced MR angiography (3D-DCE-MRA) may be the optimal vascular imaging method for preoperative evaluation of liver transplantation candidates. This study was undertaken to determine the value of 3D-DCE-MRA in the assessment of recipient vessels in orthotopic liver transplantation (OLT). METHODS: The surgical and pathological records were taken as the 'gold standards'. Eighteen cases of OLT were retrospectively analyzed to assess the image quality of MRA, including the signal-to-noise ratio (SNR) in arteries and veins, depiction of vascular variation and vessel disease, and the accuracy of vascular diameter measurement. RESULTS: 3D-DCE-MRA of 34 cases was carried out before OLT. The rates (excellent and good) showing hepatic arteries and portal vein for 3D-DCE-MRA were 94.1% (32/34) and 88.2% (30/34), respectively. The SNRs of the celiac axis and portal vein measurements from 3D-DCE-MRA were 20.58 +/- 3.74 and 13.43 +/- 4.12, and the mean diameters were 3.4 +/- 0.3 rum and 13.1 +/- 3.2 mm, respectively. There were 5 cases of vessel variation according to the Michel's classification. Of the 34 patients, 18 were compared radiologically and pathologically. The accuracy of depiction of the hepatic artery and portal vein with 3D-DCE-MRA was 100% for both; 3D-DCE-MRA precisely assessed 4 cases of more than moderate stenosis in hepatic arteries, 2 cases of small-caliber hepatic artery, 3 cases of venous stenosis at the second porta hepatis, 6 cases of collateral vasculature, I case of portal vein thrombosis and I case of portal vein aneurysm; all were confirmed pathologically. CONCLUSION: 3D-DCE-MRA may be the first choice for recipient vascular assessment before OLT.

关键词： magnetic resonance angiography liver transplantation

Efficiency of spectral CT iodine concentration value related parameters in the diagnosis of regional lymph node metastasis of gastric adenocarcinoma

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China Medical Abstracts (Internal Medicine) 2023年第1期 1-2页

作者：贾萍 dept radiol Shengjing HospChina Med Univ

Objective To analyze the efficacy of quantitative parameters related to spectral CT iodine concentration(IC) values in evaluating regional lymph node metastasis in patients with gastric adenocarcinoma.Methods The clinical data and CT images of 55 patients with gastric adenocarcinoma diagnosed by pathology from June 2021to June 2022 were collected retrospectively at ShengjingHospital of China Medical University.

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