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Metagenomic next-generation sequencing for the diagnosis of Pneumocystis jirovecii pneumonia after allogeneic hematopoietic stem cell transplantation

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China Medical Abstracts(Internal Medicine) 2024年第2期41卷 122-123页

作者：符蓉 dept hematol Nanfang HospSouth Med UnivClin Med Res CenterHematol DisGuangdong ProvGuangzhou 510515

Objective To investigate the value of metagenomic next-generation sequencing (mNGS) in the diagnosis of Pneumocystis jirovecii pneumonia (PJP) in patients undergoing allogeneic hematopoietic stem cell transplantation (allo-HSCT).Methods The data of 98patients with suspected pulmonary infection after alloHSCT who underwent pathogen detection from bronchoalveolar lavage fluid between June 2016 and August 2023 at Nanfang Hospital were analyzed.

关键词： diagnosis Pneumocystis pneumonia

Characteristics and impact factors of SARS-CoV-2 infection in adult patients with relapsed/refractory B-cell non-Hodgkin lymphoma receiving chimeric antigen receptor T-cell therapy

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China Medical Abstracts(Internal Medicine) 2024年第1期41卷 58-59页

作者：葛童 dept hematol Tongji HospTongji Med CollHuazhong Univ Sci&TechnolWuhan 430030

Objective To explore the clinical characteristics and treatment of COVID-19 infection in patients with relapsed/refractory B-cell non-Hodgkin lymphoma before and after receiving chimeric antigen receptor T-cell therap... 详细信息

关键词： patients infection lymphoma

A single-center retrospective analysis of autologous hematopoietic stem cell transplantation for the treatment of multiple myeloma in the elderly

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China Medical Abstracts(Internal Medicine) 2024年第1期41卷 55-55页

作者：王婧 dept hematol Soochow Hopes Hematol HospSuzhou 215128

Objective To evaluate the efficacy and safety of autologous hematopoietic stem cell transplantation (autoHSCT) for the treatment of multiple myeloma (MM) in elderly patients aged over 65 *** In this retrospective analysis,the efficacy and safety of autoHSCT for the treatment of MM was examined in 28patients aged> 65 years diagnosed and treated at Soochow Hopes hematology Hospital between March 1.

关键词： hematopoietic myeloma treatment

Brillouin expanded time-domain analysis based on dual optical frequency combs

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Light(Science & Applications) 2024年第8期13卷 1534-1544页

作者： Jae Hyeong Youn Kwang Yong Song Sonia Martin-Lopez Miguel Gonzalez-Herraez María R.Fernández-Ruiz dept.of Physics Chung-Ang UniversitySeoulKorea dept.of Electronics Universidad de AlcaláMadridSpain

Brillouin Optical Time-Domain Analysis(BOTDA)is a widely-used distributed optical fiber sensing technology employing pulse-modulated pump waves for local information retrieval of the Brillouin gain or loss *** spatial resolution of BOTDA systems is intrinsically linked to pulse duration,so high-resolution measurements demand high electronic bandwidths inversely proportional to the *** paper introduces Brillouin Expanded Time-Domain Analysis(BETDA)as a modified BOTDA system,simultaneously achieving high spatial resolution and low detection *** two optical frequency combs(OFCs)with different frequency intervals as pump and probe,local Brillouin gain spectra are recorded by their spectral beating traces in an expanded time domain.A 2-cm-long hotspot located in a 230m single-mode fiber is successfully measured in the time domain with a detection bandwidth of less than 100 kHz using dual OFCs with tailored spectral phase,line spacing,and bandwidth.

关键词： pump optical fiber

A Review on Soft Ionic Touch Point Sensors

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ENERGY & ENVIRONMENTAL MATERIALS 2024年第6期7卷 193-208页

作者： Lee, Gibeom Lee, Donghyun Im, Gwang-Bum Lee, Younghoon Gachon Univ Dept Mech Engn 1342 Seongnamdaero Seongnam 13120 South Korea Harvard Med Sch Dept Surg Boston MA 02115 USA

A touch sensor is an essential component in meeting the growing demand for human-machine interfaces. These sensors have been developed in wearable, attachable, and even implantable forms to acquire a wide range of information from humans. To be applied to the human body, sensors are required to be biocompatible and not restrict the natural movement of the body. Ionic materials are a promising candidate for soft touch sensors due to their outstanding properties, which include high stretchability, transparency, ionic conductivity, and biocompatibility. Here, this review discusses the unique features of soft ionic touch point sensors, focusing on the ionic material and its key role in the sensor. The touch sensing mechanisms include piezocapacitive, piezoresistive, surface capacitive, piezoelectric, and triboelectric and triboresistive sensing. This review analyzes the implementation hurdles and future research directions of the soft ionic touch sensors for their transformative potential. This paper introduces the increasing importance of touch sensors in human-machine interfaces and the role of soft ionic materials in enhancing the functionality of touch sensors. It provides detailed explanations of various touch sensor mechanisms, including piezocapacitive, piezoresistive, surface capacitive, piezoelectric, triboelectric, and triboresistive. It also discusses the challenges of minimizing humidity sensitivity, improving resilience, and suppressing unwanted electrochemical reactions, along with future directions for touch sensors. image

关键词： iontronics ionic materials soft materials touch sensors TRIBOELECTRIC NANOGENERATORS BRAIN-TISSUE TRANSPARENT HYDROGEL STRENGTH

Experimental validation of double-fed induction generator in oscillating water column using circulatory system-based optimization

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CLEAN ENERGY 2024年第2期8卷 127-143页

作者： Elnaghi, Basem E. Ismaiel, Ahmed M. Abdel-Kader, Fathy El Sayed Mohammed, Reham H. Abelwhab, M. N. Suez Canal Univ Elect Power & Machine Dept Ismailia Egypt Menoufia Univ Fac Engn Elect Machine & Power Dept Menoufia Egypt Suez Canal Univ Comp & Control Dept Ismailia Egypt

This paper validates the optimal operation for a grid-connected double-fed induction generator (DFIG) in an oscillating water column power plant (OWCPP). This study presents a novel optimization technique called the circulatory system-based optimization (CSBO) approach to develop six adaptive fuzzy logic controllers (AFLCs) with 30 parameters and compare them to chaotic-billiards optimization (C-BO) and genetic algorithm (GA). The proposed controller is also compared with a proportional-integral differential (PID) controller based on a self-adaptive global-best harmony search (SGHS). CSBO-based AFLCs are fully investigated under different scenarios and experimented with using a real-time interface DSP1104. The results of using CSBO-AFLCs revealed a fast time response, fast convergence, less overshoot and minimal error compared with those achieved with C-BO-AFLC, SGHS-PID and GA-AFLC during different case studies. The CSBO-based AFLCs ensure maximum power from the DFIG in an OWCPP and enhance dynamic response with very low errors. The results show that the CSBO shows better power tracking by 25% as compared with C-BO, by 45% when compared with the GA and by 56% when compared with PID. Moreover, the integral absolute errors of six controllers are investigated to demonstrate the feasibility of CSBO-AFLC. The root mean square of the errors of six controllers using CSBO is improved by 68.27% when compared with GA, by 22.57% when compared with C-BO and by 38.42% when compared with PID. These indicators demonstrate the feasibility of CSBO when compared with other algorithms with the same OWCPP. This paper validates the optimal operation of a grid-connected double-fed induction generator in an oscillating water column using a novel optimization technique called the circulatory system-based optimization approach. Experiments using a real-time simulator demonstrate the feasibility of the approach when compared with other algorithms. Graphical Abstract

关键词： circulatory system-based optimization approach adaptive fuzzy logic controller grid-tied oscillating water column power plant maximum power point tracking WAVE ENERGY-CONVERSION DESIGN OPTIMIZATION ALGORITHM CONTROLLER TURBINE

Efficacy of different regimens and prognostic factors in patients with first relapsed multiple myeloma treated after front-line bortezomib,cyclophosphamide,and dexamethasone

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China Medical Abstracts(Internal Medicine) 2024年第1期41卷 56-56页

作者：陈苗 dept hematol PUMC&CAMSBeijing 100730

Objective *** the efficacy of second-line regimens and prognostic factors in patients with firstrelapsed multiple myeloma (MM) treated with bortezomib,cyclophosphamide,and dexamethasone(BCD).Methods Clinical data were collected in firstrelapsed MM patients after BCD treatment from three tertiary hospitals in north China from July 2009 to October 2022.

关键词： regimen patients relapse

An experimental study on optimizing parameters for sand consolidation with organic-inorganic silicate solutions

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PETROLEUM 2024年第3期10卷 483-493页

作者： Mishra, Saurabh Chauhan, Geetanjali Ojha, Keka Ctr Adv Studies Dept Energy Sci & Technol Lucknow India Indian Inst Petr & Energy Dept Petr Engn & Earth Sci Visakhapatnam India Indian Inst Technol ISM Dept Petr Engn Dhanbad India

Sand production along with the oil/gas detrimentally affects the oil production rate, downhole & subsurface facilities. Mechanical equipment and various chemicals like epoxy resin, furan resin, phenolic resin, etc. are used in the industry to reduce or eliminate this problem. In the present study, a blend of organic and inorganic silicates are used to consolidate loose sand in the presence and absence of crude oil using a core flooding apparatus. The effects of chemical concentration, pH, curing temperature and time, and the presence of residual oil on the consolidation treatment results such as compressive strength and permeability retention, were investigated and optimized. FT-IR and FE-SEM characterization techniques were employed to investigate the interaction between the chemical molecules and the sand grains. The current binding agent exhibited a viscosity of less than 6 cP at room temperature, which facilitates efficient pumping of binding agent into the desired formation through the well bore. The developed mixture demonstrated consolidation properties across all pH conditions. Furthermore, during the experimental investigation, the curing time and temperature was carefully optimized at 12 h and 423.15K, respectively to achieve the highest compressive strength of 2021 psi while achieving the permeability retention of 64%. The current chemical system exhibited improved consolidation capacity and can be effectively utilized for sand consolidation treatment in high-temperature formations. (c) 2023 Southwest Petroleum University. Publishing services by Elsevier B.V. on behalf of KeAi Communications Co. Ltd. This is an open access article under the CC BY-NC-ND license (http:// ***/licenses/by-nc-nd/4.0/).

关键词： Chemical sand consolidation Rheology Compressive strength Permeability retention Silicate system Curing SPECTRA GEL SPECTROSCOPY

Evaluating transient behaviour of large-scale photovoltaic systems during lightning events using enhanced finite difference time domain method with variable cell size approach

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HIGH VOLTAGE 2024年第3期9卷 636-647页

作者： Hetita, Ibrahim Mansour, Diaa-Eldin A. Han, Yang Yang, Ping Wang, Congling Darwish, Mohamed M. F. Lehtonen, Matti Zalhaf, Amr S. Univ Elect Sci & Technol China UESTC Sch Mech & Elect Engn Chengdu Peoples R China Helwan Univ Fac Engn Elect Power & Machines Engn Dept Cairo Egypt Tanta Univ Fac Engn Elect Power & Machines Engn Dept Tanta Egypt Egypt Japan Univ Sci & Technol Fac Engn Dept Elect Power Engn Alexandria Egypt Benha Univ Fac Engn Shoubra Dept Elect Engn Cairo Egypt Aalto Univ Sch Elect Engn Dept Elect Engn & Automation Espoo Finland GMC Dept Med Srinagar Jammu And Kashm India

Photovoltaic (PV) arrays are usually installed in open areas; hence, they are vulnerable to lightning strikes that can result in cell degradation, complete damage, service disruption, and increased maintenance costs. As a result, it is imperative to develop an effective and efficient lightning protection system by evaluating the transient behaviour of PV arrays during lightning events. The aim is to evaluate the transient analysis of large-scale PV systems when subjected to lightning strikes using the finite difference time domain (FDTD) technique. Transient overvoltages are calculated at various points within the mounting system. To optimise the FDTD method's execution time and make it more suitable for less powerful hardware, a variable cell size approach is employed. Specifically, larger cell dimensions are used in the earthing system and smaller cell dimensions are used in the mounting system. The FDTD method is utilised to calculate the temporal variation of transient overvoltages for large-scale PV systems under different scenarios, including variations in the striking point, soil resistivity, and the presence of a metal frame. Simulation results indicate that the highest transient overvoltages occur at the striking point, and these values increase with the presence of a PV metal frame as well as with higher soil resistivity. Furthermore, a comparison is performed between the overvoltage results obtained from the FDTD approach and the partial element equivalent circuit (PEEC) method at the four corner points of the mounting systems to demonstrate the superior accuracy of the FDTD method. Besides, a laboratory experiment is conducted on a small-scale PV system to validate the simulation results. The calculated overvoltages obtained from the FDTD and PEEC methods are compared with the measured values, yielding a mean absolute error of 5% and 11% for the FDTD and PEEC methods, respectively, thereby confirming the accuracy of the FDTD simulation model.

关键词： FDTD METHOD MODEL