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Acute Leukemia in Niger: Epidemiological, Diagnostic and Therapeutic Aspects

Open Journal of Blood Diseases 2024年第3期14卷 81-90页

作者： Amadou Djibrilla-Almoustapha Badé Malam-Abdou Abdourahamane Yacouba Moussa Souley Moustapha Maman Brah Moustapha Elhadji-Chefou Boubacar Marou-Soumana Samaila Aboubacar Ousseini Fanta Maman Rabiou Badé Oumarou Adamou-Chaibou Department of Hematology-Oncology National Hospital of Niamey Niamey Niger Faculty of Health Sciences University of Abdou Moumouni Niamey Niger Department of Medicine Zinder Hospital Regional Niger departtment of biology Amirou Boubacar Diallo National Hospital Niamey Niger Faculty of Health Sciences University of Dan Dicko Dankouloudo of Maradi Maradi Niger Laboratory of biology National Hospital of Niamey Niamey Niger

Objective: Improve the care of patients followed for acute leukemia in the Oncohematology department of the National Hospital of Niamey. Methods: This was a prospective study, over a period of 2 years from January 1, 2018 to December 31, 2019, in patients with acute leukemia in the Oncohematology department of the National Hospital of Niamey (HNN), whose diagnosis was made on a blood smear associated with a myelogram and immunophenotyping and who were consenting. Results: We collected 25 cases of acute leukemia confirmed by myelogram and immunophenotyping. The mean age of the patients was 31.32 years, with a predominance of women, a sex ratio of 0.92. Pupils and students were in the majority with 40% and most came from the Niamey region, i.e. 68%. Anemic syndrome was the most common clinical sign in 96%. ALL predominated in 64% of cases. On the blood count, the hyperleukocytosis was more marked in AML (mean white count: 197256.6 elts/mm3) than in ALL (137891.6 elts/mm3), it was the same for thrombocytopenia which is more marked in AML (75588.89/mm3) than in ALL (52156.25/mm3). Therapeutically, 52% of patients received chemotherapy. The mean overall survival was 16.223 ± 3.191 months, including a mean survival for AML of 6.853 ± 1200 months compared to 21.720 ± 5.920 months for ALL. Conclusion: Acute leukemia still remains a major problem in our context, due to the precariousness of limited financial, diagnostic and therapeutic resources. Thus reflecting in our results, the increasing number of cases, the diagnostic delay and the guarded prognosis. This is the reality in several other countries in the sub-region and even in certain developed countries.

关键词： Acute Leukemia ALL AML Hematology-Niamey National Hospital (HNN) Niger

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Modeling and Control of Active Suspensions for MDOF Vehicle

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Tsinghua Science and Technology 2003年第2期8卷 224-230页

作者：李克强郑四发杨殿阁连小珉永井正夫 State Key Laboratory of Automotive Safety and Energy Departtment of Automative EngineeringTsinghua UniversityBeijing 100084China State Key Laboratory of Automotive Safety and Energy Department of Automative EngineeringTsinghua UniversityBeijing 100084China Tokyo University of Agriculture and Technology 2-24-16NakachoKoganeishi Tokyo 184-8588Japan

An MDOF model was developed including the influence of factors such as the engine, the seats, and the passengers to describe vehicle motion using a reduced order model of the controller designed by using the H∞ control method. The control system performance has been investigated by comparing the H∞ controller with a linear quadratic (LQ) controller.

关键词： Control equipment Control systems Degrees of freedom (mechanics)

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