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Extrapleural solitary fibrous tumor of the thyroid gland: A case report and review of literature

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World Journal of Clinical Cases 2020年第4期8卷 782-789页

作者： Yong Joon Suh Jung Ho Park Jae Hyeon Jeon Sanchir-Erdene Bilegsaikhan Department of Breast and endocrine surgery Hallym University Sacred Heart HospitalGyeonggi-do 14068South Korea Department of Biomedical Science Hallym UniversityChuncheon 24252South Korea

BACKGROUND Solitary fibrous tumor(SFT)is an uncommon mesenchymal neoplasm that arises from the pleura.A few SFTs have also been described in extrapleural ***,SFT of the thyroid gland is ***,we report a case of extrapleural SFT on the thyroid gland,in addition to a literature *** SUMMARY A 59-year-old man visited our hospital in July 2017 complaining of a large mass in his *** thyroid function test results,including antibody levels,were within the normal *** showed a 4.7 cm×4.0 cm×3.2 cm solitary mass of intermediate suspicion in the left thyroid lobe.A fine-needle aspiration biopsy was subsequently *** pathologist reported a benign follicular ***,the size of this nodule increased to 5.5 cm×5.0 cm×3.4 cm by April *** a multidisciplinary discussion,a left lobectomy was performed in May *** specimen showed a well-demarcated,partly encapsulated,soft nodule of whitish and tan/brown color on the cut *** microscopy revealed high cellularity with moderate cytologic *** mitotic count was 5/10 high-power *** was no tumor necrosis or lymphovascular *** tumor was CD34-positive and signal transducer and activator of transcription *** thyroid transcription factor-1 nor cytokeratin expression was *** Ki-67 showed intermediate proliferative *** final diagnosis was extrapleural SFT of the thyroid gland with a clear resection *** patient was discharged without complication three days after the *** In the literature,extrapleural SFT of the thyroid gland has been reported to behave indolently with the capacity for recurrence and rare metastasis,although surgical resection is the treatment of *** this disease entity is important for accurate diagnosis and proper management.

关键词： Solitary fibrous tumor Mesenchymal neoplasm Thyroid gland surgery Case report Review

Bilateral chylothorax following left supraclavicular lymph node dissection for breast cancer: one case report and literature review

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Chinese Journal of Cancer 2014年第6期33卷 317-320页

作者： De-Juan Yang Guo-Sheng Ren Xiao-Yi Wang Department of Breast and endocrine surgery The First Affiliated Hospital of Chongqing Medical University

Chylothorax is a rare complication of neck dissection, and bilateral chylothorax is even rarer. However, both are potentially serious and sometimes life-threatening, especially those that are associated with left neck dissection for head and neck neoplasms. We report one case of bilateral chylothorax following left supraclavicular dissection for breast cancer. This case was treated successfully with a new conservative management approach.

关键词：乳腺癌淋巴结乳糜锁骨复习文献头颈部肿瘤并发症

Can we talk about “futile surgery” for the upfront treatment of the perihilar cholangiocarcinoma?

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Hepatobiliary surgery and Nutrition 2024年第4期13卷 672-674页

作者： Maria Conticchio David Fuks Stylianos Tzedakis Unit of Hepatobiliairy and Pancreatic surgery Ente Ecclesiastico F.MiulliAcquaviva delle FontiBariItaly Unit of Hepatobiliary Digestive and Endocrine SurgeryCochin HospitalUniversitéParis CitéParisFrance

In this work(1),Ratti et *** to identify a subgroup of patients with perihilar cholangiocarcinoma(PHC)for whom the benefit of surgery could be compromised by morbidity,mortality and the risk of early tumor *** for this study come from a multi-institutional database that includes consecutive patients undergoing elective surgery for PHC in 27 Western centers(with experience of more than 15 major liver resections per year)starting in January *** from 2,271 patients were analyzed *** there is neither international consensus on preoperative management nor standardization of surgical technique,the indications for resection were validated at a local multidisciplinary consultation *** optimization was standardized with endoscopic or percutaneous biliary drainage to treat jaundice and the performance of portal embolization was proposed in the event of insufficient volume of the future remaining liver.

关键词： Perihilar cholangiocarcinoma(PHC) upfront surgery predictive risk score

Hepatocellular carcinoma presenting as an extrahepatic mass:A case report and review of literature

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World Journal of Gastrointestinal Oncology 2024年第5期16卷 2241-2252页

作者： Wei Kelly Wu Krutika Patel Chandrasekhar Padmanabhan Kamran Idrees Department of surgery Vanderbilt University Medical CenterNashvilleTN 37232United States Department of Pathology Microbiology and ImmunologyVanderbilt University Medical CenterNashvilleTN 37232United States Division of Surgical Oncology and endocrine surgery Department of SurgeryVanderbilt University Medical CenterNashvilleTN 37232United States

BACKGROUND Hepatocellular carcinoma(HCC)is a primary liver tumor generally diagnosed based on radiographic *** disease is typically associated with increased tumor diameter,multifocality,and vascular *** report a case of a patient who presented with extrahepatic HCC metastasis to a portocaval lymph node with occult hepatic primary on computed tomography(CT).We review the literature for cases of extrahepatic HCC presentation without known hepatic lesions and discuss strategies to differentiate between metastatic and ectopic *** SUMMARY A 67-year-old male with remotely treated hepatis C was referred for evaluation of an enlarging portocaval,mixed cystic-solid *** CT evaluations demonstrated steatosis,but no cirrhosis or liver *** ultrasound demonstrated a normal-appearing pancreas,biliary tree,and *** needle aspiration yielded atypical *** differential diagnosis included duodenal or pancreatic cyst,lymphoproliferative cyst,stromal or mesenchymal lesions,nodal involvement from gastrointestinal or hematologic malignancy,or duodenal gastrointestinal stromal *** review by a multidisciplinary tumor board,the patient underwent open surgical resection of a 5.2 cm×5.5 cm retroperitoneal mass with pathology consistent with moderately-differentiated *** resonance imaging(MRI)subsequently demonstrated a 1.2 cm segment VIII hepatic lesion with late arterial enhancement,fatty sparing,and intrinsic T1 *** fetoprotein was 23.3 ng/*** patient was diagnosed with HCC with portocaval nodal ***:We surveyed the literature for HCC presenting as extrahepatic masses without history of concurrent or prior intrahepatic *** identified 18 cases of extrahepatic HCC ultimately found to represent metastatic lesions,and 30 cases of extrahepatic HCC found to be primary,ectopic *** Hepatocellular carcinoma can seldomly present with extrahepatic metastasis in the setting of

关键词： Extrahepatic Metastasis Portocaval Lymph node Case report

Electrophysiological neuromonitoring of the laryngeal nerves in thyroid and parathyroid surgery: A review

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World Journal of Experimental Medicine 2015年第2期5卷 120-123页

作者： Ahmed Deniwar Parisha Bhatia Emad Kandil Division of endocrine and Oncologic surgery Department of SurgeryTulane University School of Medicine

Recurrent laryngeal nerve(RLN) injury is one of the most common complications of thyroid surgery. Injury to the external branch of the superior laryngeal nerve is less obvious and affects the voice variably; however, it can be of great significance to professional voice users. Recent literature has led to an increase in the use of neuromonitoring as an adjunct to visual nerve identification during thyroid surgery. In our review of the literature, we discuss the application, efficacy and safety of neuromonitoring in thyroid surgery. Although intraoperative neuromonitoring(IONM) contributes to the prevention of laryngeal nerves injury, there was no significant difference in the incidence of RLN injury in thyroid surgery when IONM was used compared with visual identification alone. IONM use is recommended in high risk patients; however, there are no clear identification criteria for what constitutes "high risk". There is no clear evidence that IONM decreases the risk of laryngeal nerve injury in thyroid surgery. However, continuous IONM provides a promising tool that can prevent imminent nerve traction injury by detecting decreased amplitude combined with increased latency.

关键词： Neuromonitoring Superior laryngeal nerve Recurrent laryngeal nerve Thyroid surgery

Roux-en-Y augmented gastric advancement: An alternative technique for concurrent esophageal and pyloric stenosis secondary to corrosive intake

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World Journal of Gastrointestinal surgery 2016年第12期8卷 766-769页

作者： Talat Waseem Asad Azim Muhammad Hasham Ashraf Khawaja M Azim Division of Surgical Oncology and endocrine surgery Department of Surgery Shalamar Medical and Dental College

Select group of patients with concurrent esophagealand gastric stricturing secondary to corrosive intake requires colonic or free jejunal transfer. These technically demanding reconstructions are associated with significant complications and have up to 18% ischemic conduit necrosis. Following corrosive intake, up to 30% of such patients have stricturing at the pyloro-duodenal canal area only and rest of the stomach is available for rather less complex and better perfused gastrointestinal reconstruction. Here we describe an alternative technique where we utilize stomach following distal gastric resection along with Roux-en-Y reconstruction instead of colonic or jejunal interposition. This neo-conduit is potentially superior in terms of perfusion, lower risk of gastro-esophageal anastomotic leakage and technical ease as opposed to colonic and jejunal counterparts. We have utilized the said technique in three patients with acceptable postoperative outcome. In addition this technique offers a feasible reconstruction plan in patients where colon is not available for reconstruction due to concomitant pathology. Utility of this technique may also merit consideration for gastroesophageal junction tumors.

关键词： Corrosive strictures Roux-en-Y augmented gastric advancement Colonic interposition

The role of exosomal microRNAs;focus on clinical applications in breast cancer

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Cancer Drug Resistance 2019年第3期2卷 847-861页

作者： Aiko Sueta Yutaka Yamamoto Hirotaka Iwase Department of Breast and endocrine surgery Kumamoto University Graduate School of Medical Sciences1-1-1HonjoChuo-kuKumamoto 860-8556Japan

Despite several advances in targeted therapies for breast cancer,breast-cancer-associated death remains high in *** is partially due to the lack of reliable markers predicting metastatic disease or recurrence after initial *** research into the clinical validity of circulating cancer-specific biomarkers as a“liquid biopsy”is of growing *** these,exosomal microRNAs(miRNAs)are promising candidate biomarkers for clinical use in breast *** addition to their diagnostic value,exosomal miRNAs play an important role in predicting clinical outcome or treatment *** this review,it is focused on the findings concerning exosomal miRNAs in relation to disease detection,prognostic impact and therapeutic effect in breast cancer,and discuss their clinical utility.

关键词： Exosomal miRNA breast cancer liquid biopsy

A Double-Blinded Prospective Randomised Controlled Trial to Assess the Efficacy of Glubran-2 in Reducing Seroma Formation after a Mastectomy with or without Axillary Dissection

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Advances in Breast Cancer Research 2017年第4期6卷 117-128页

作者： Zackariah Clement Peter Shin Clive Hoffmann Michael Eaton William McLeay Breast and endocrine surgery Unit Flinders Medical Centre Adelaide Australia

Background and Purpose: Seroma formation is a common complication following a mastectomy and axillary surgery. Decreasing the dead space is believed to decrease seroma formation. The aim of this study is to compare the incidence of seroma formation with the use of Glubran-2 versus normal saline during the wound closure in participants undergoing mastectomy with or without axillary dissection. Methods: This multicentre, prospective, double-blinded, randomised controlled trial, enrolled women 18 years of age or older with breast cancer, who were underwent total or partial mastectomy, with or without axillary dissection. Participants were randomised to Glubran-2 or Saline arm. The primary outcome was the volume and duration of wound seroma. Secondary outcome was post-operative wound infection. Results: A total of 76 women were randomised and there was no loss to follow-up or mortality. The total seroma volume was higher in the Glubran-2 arm. The duration of seroma was higher in the mastectomy and axillary dissection group in the Glubran-2 arm (P = 0.69). Elderly and participants with higher BMI had a higher volume of seroma. Post-operative infection rate was higher in the Glubran-2 arm (13.2% vs. 5.6%;P = 0.26). There was no statistically significant difference between the groups. Conclusion: Our study did not show any benefit with the use of Glubran-2 in mastectomy and axillary surgery in reducing the risk of seroma formation. In elderly and obese participants the use of Glubran-2 showed an increase in seroma formation and post-operative wound infection.

关键词： Breast Cancer Mastectomy Axillary Dissection Seroma Glubran Cyanoacrylate Glue

Interpatient heterogeneity in hepatic microvascular blood flow during vascular inflow occlusion (Pringle manoeuvre)

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Hepatobiliary surgery and Nutrition 2021年第3期10卷 413-415页

作者： Eric Felli Edoardo Maria Muttillo Emanuele Felli Hepatology Department of Biomedical ResearchInselspitalUniversity of BernBernSwitzerland Department of General surgery Sant’Andrea HospitalSapienza University of RomeRomeItaly Digestive and endocrine surgery Nouvel Hopital CivilUniversity of StrasbourgStrasbourgFrance IHU Strasbourg Institute of Image-Guided SurgeryStrasbourgFrance

Hepatic inflow occlusion(Pringle manoeuvre),is a widely used technique,consisting in temporary intermittent or continuous clamping of the hepatic *** technique was described in 1908 by Pringle to minimize blood loss during emergency surgery for liver ***,in hepatobiliary surgery,the Pringle manoeuvre assumes a primary role especially in complex liver resections where an intraoperative blood loss could be ***.

关键词： Pringle hepatic occlusion