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Semen Quality in Infertile Men with a History of Unilateral Cryptorchidism

Journal of Reproduction and Contraception 2004年第3期15卷 139-143页

作者： P. Tzvetkova Wei-Jie ZHU D. Tzvetkov department of lmmunoneuroendocrinology Institute of Biology and Reproductive hnmunology Bulgarian Academy of Science Sofia Bulgaria Center for Reproductive hnmunology Research dinan University Guangzhou 510632 China department of Urology Medical University Sofia Bulgaria

Objective To evaluate semen quality in infertile men with a history of unilateral cryptorchidism Methods Semen samples were obtained from 47 infertile men with a history of unilateral cryptorchidism. Semen analysis and membrane integrity including both eosin Y stain and hyo-osmotic swelling tests were performed using standard procedures. All men were divided into three groups according to their age at surgery of orchidopexy as follows： group A, 2-7 years （n=23）, group B, 8-13 years （n=14） and group C, 14-17years （n=10）. Results There was wide range for sperm count and motility for all the subjects studied. Majority of men had high percentage of abnormal sperm morphology. Among the three groups of men, group A and B had significantly higher sperm count, motility and membrane integrity than that of group C. Group C also had the highest frequency of oligoasthenoteraozoospermia （50%） than group A （17%） and group B （35%）. Conclusion Semen quality of men with a history of unilateral cryptorchidism appears to be related to their age of performing orchidopexy. Surgery at early age of childhood may improve spermatogenesis which results in better semen quality in adulthood.

关键词： cryptorchidism sperm infertility orchidopexy

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